Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in EYPT held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | SUVRETTA CAPITAL MANAGEMENT, LLC | 8.3M | $106.9M | +6.0% | 9.901% | 2.90% |
| 2 | Cormorant Asset Management, LP | 8.3M | $106.5M | 0.0% | 9.863% | 5.35% |
| 3 | BlackRock, Inc. | 7.2M | $92.5M | +5.7% | 8.565% | 0.00% |
| 4 | FEDERATED HERMES, INC. | 5.7M | $73.1M | -5.8% | 6.766% | 0.12% |
| 5 | FRANKLIN RESOURCES INC | 5.0M | $65.1M | +1.4% | 6.025% | 0.02% |
| 6 | JANUS HENDERSON GROUP PLC | 3.6M | $46.4M | +22.6% | 4.298% | 0.02% |
| 7 | VANGUARD CAPITAL MANAGEMENT LLC | 3.6M | $45.9M | — | 4.248% | 0.00% |
| 8 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 3.3M | $42.5M | -29.8% | 3.938% | 0.07% |
| 9 | Paradigm Biocapital Advisors LP | 3.1M | $40.5M | -14.9% | 3.750% | 0.83% |
| 10 | COMMODORE CAPITAL LP | 2.8M | $36.4M | — | 3.371% | 2.11% |
| 11 | STATE STREET CORP | 2.1M | $27.0M | +14.3% | 2.503% | 0.00% |
| 12 | CITADEL ADVISORS LLC | 2.0M | $25.8M | — | 2.393% | 0.01% |
| 13 | GEODE CAPITAL MANAGEMENT, LLC | 2.0M | $25.6M | +4.4% | 2.367% | 0.00% |
| 14 | abrdn plc | 1.7M | $22.4M | +8.2% | 2.075% | 0.04% |
| 15 | BALYASNY ASSET MANAGEMENT LLC | 1.4M | $18.5M | +141.7% | 1.717% | 0.06% |
| 16 | Parkman Healthcare Partners LLC | 1.4M | $17.5M | +24.5% | 1.617% | 1.81% |
| 17 | EVENTIDE ASSET MANAGEMENT, LLC | 1.2M | $16.1M | — | 1.486% | 0.27% |
| 18 | MORGAN STANLEY | 1.1M | $14.1M | +390.0% | 1.308% | 0.00% |
| 19 | Essex Woodlands Management, Inc. | 1.1M | $14.0M | 0.0% | 1.295% | 5.58% |
| 20 | ORBIMED ADVISORS LLC | 1.1M | $13.8M | -56.7% | 1.276% | 0.29% |
| 21 | 5AM Venture Management, LLC | 1.1M | $13.5M | 0.0% | 1.253% | 3.76% |
| 22 | Rosalind Advisors, Inc. | 1.0M | $13.4M | +50.2% | 1.237% | 5.48% |
| 23 | Blue Owl Capital Holdings LP | 913K | $11.8M | +132.4% | 1.089% | 3.16% |
| 24 | HSBC HOLDINGS PLC | 833K | $10.7M | — | 0.995% | 0.01% |
| 25 | STEMPOINT CAPITAL LP | 811K | $10.5M | +129.1% | 0.968% | 2.76% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in EYPT — a direct measure of their conviction.
Filings activity in EYPT during Q1 2026, grouped by how each filer changed its position.
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 181 | +14% | 105.10% | 33.62 pp | $1.15B | 24% |
| Q4 2025 | 159 | +9.7% | 138.72% | +48.21 pp | $1.51B | +53% |
| Q3 2025 | 145 | +2.8% | 90.51% | +30.86 pp | $988M | +52% |
| Q2 2025 | 141 | 6.6% | 59.65% | +24.73 pp | $651M | +71% |
| Q1 2025 | 151 | +5.6% | 34.92% | 12.23 pp | $381M | 26% |
| Q4 2024 | 143 | +6.7% | 47.15% | +7.66 pp | $515M | +19% |
| Q3 2024 | 134 | 10% | 39.49% | 2.28 pp | $431M | 5.5% |
| Q2 2024 | 149 | — | 41.77% | — | $456M | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying EYPT stock.
Based on Q1 2026 13F filings, institutional ownership of EyePoint Pharmaceuticals, Inc. stands at 105.1%, held across 181 reporting institutions.
SUVRETTA CAPITAL MANAGEMENT, LLC is the largest reported institutional holder of EYPT, with approximately 8,296,375 shares worth $0.11B as of Q1 2026.
Yes — 1 widely-followed marquee investor appear among the top 25 institutional holders of EYPT, including CITADEL ADVISORS LLC.
Our composite Smart Money Score for EYPT is 43 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
48 institutions opened new positions in EYPT during Q1 2026, while 26 fully exited. 33 added to existing positions and 99 trimmed.
EYPT institutional ownership fell by 33.62 percentage points quarter-over-quarter, with a net change of +22 holders.
The top 10 institutions account for 57.2% of all reported 13F value in EYPT, and the top 25 account for 79.3%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.