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HRTX logoHeron Therapeutics, Inc. (HRTX) P/E Ratio History

Historical price-to-earnings valuation from 1997 to 2006

Current P/E
-10.1
Undervalued
5Y Avg P/E
60.9
-117% vs avg
PE Percentile
0%
Low
PEG Ratio
N/A
N/A
TTM EPS$-0.12
Price$1.21
5Y PE Range1.0 - 495.6
Earnings YieldN/A

Loading P/E history...

HRTX Valuation Context

How does the current P/E compare to historical and market benchmarks?

vs. 5Y Average
-10.1vs60.9
-117%
Cheap vs History
vs. Healthcare
-10.1vs22.2
-145%
Below Sector
vs. S&P 500
-10.1vs24.9
-140%
Below Market
PEG Analysis
N/A
P/E ÷ EPS Growth
Based on -35% EPS growth (1Y)
Export Data

P/E Ratio Analysis

As of May 8, 2026, Heron Therapeutics, Inc. (HRTX) trades at a price-to-earnings ratio of -10.1x, with a stock price of $1.21 and trailing twelve-month earnings per share of $-0.12.

The current P/E is 117% below its 5-year average of 60.9x. Over the past five years, HRTX's P/E has ranged from a low of 1.0x to a high of 495.6x, placing the current valuation at the 0th percentile of its historical range.

Compared to the Healthcare sector median P/E of 22.2x, HRTX trades at a 145% discount to its sector peers. The sector includes 241 companies with P/E ratios ranging from 0.0x to 176.0x.

Relative to the broader market, HRTX trades at a notable discount to the S&P 500 median P/E of 24.9x. Investors should consider the company's growth prospects, competitive position, and earnings quality when evaluating whether the current valuation is justified.

For a comprehensive intrinsic value estimate using discounted cash flow analysis, see our HRTX DCF Valuation Calculator →

Note: P/E ratio is just one valuation metric. It does not account for balance sheet strength, cash flow quality, or growth sustainability. Always conduct comprehensive due diligence before making investment decisions.

HRTX P/E vs Peers

P/E ratio compared to closely matched public peers

CompanyMarket CapP/E RatioPEG RatioEPS Growth (1Y)
PCRX logoPCRXPacira BioSciences, Inc.
$911M144.7-+107%
INVA logoINVAInnoviva, Inc.
$2B6.9Lowest0.67Best+817%Best
HRMY logoHRMYHarmony Biosciences Holdings, Inc.
$2B11.4-+8%
MCK logoMCKMcKesson Corporation
$90B28.60.73+15%

Peers sorted by market capitalization. P/E below peers may indicate undervaluation or lower growth expectations. Consider PEG ratio for growth-adjusted comparison.

HRTX Historical P/E Data (1997–2006)

Quarterly P/E ratios calculated from closing price and TTM EPS

QuarterDatePriceTTM EPSP/E Ratiovs Avg
FY2006 Q2Fri Jun 30 2006 00:00:00 GM$140.00$32.534.3x-93%
FY2006 Q1Fri Mar 31 2006 00:00:00 GM$160.00$38.944.1x-93%
FY2001 Q2Sat Jun 30 2001 00:00:00 GM$240.00$150.941.6x-97%
FY2001 Q1Sat Mar 31 2001 00:00:00 GM$165.00$153.151.1x-98%
FY2000 Q4Sun Dec 31 2000 00:00:00 GM$190.00$160.791.2x-98%
FY2000 Q3Sat Sep 30 2000 00:00:00 GM$170.00$172.651.0x-98%
FY2000 Q2Fri Jun 30 2000 00:00:00 GM$302.50$15.8519.1x-69%
FY2000 Q1Fri Mar 31 2000 00:00:00 GM$400.00$20.2719.7x-68%
FY1999 Q4Fri Dec 31 1999 00:00:00 GM$275.00$23.4711.7x-81%
FY1999 Q3$330.00$22.2914.8x-76%
FY1999 Q2Wed Jun 30 1999 00:00:00 GM$560.00$22.2925.1x-59%
FY1999 Q1Wed Mar 31 1999 00:00:00 GM$350.00$23.5814.8x-76%

Average P/E for displayed period: 60.9x

See HRTX's True Return

Price is only half the story. See total return with reinvested dividends.

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Is HRTX Undervalued?

DCF intrinsic value, peer multiples, and analyst estimates — see what the stock is really worth.

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Compare HRTX vs DBVT

Side-by-side business, growth, and profitability comparison vs DBV Technologies S.A..

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HRTX — Frequently Asked Questions

Quick answers to the most common questions about buying HRTX stock.

Is HRTX stock overvalued or undervalued?

HRTX trades at -10.1x P/E, below its 5-year average of 60.9x. At the N/A percentile of historical range, the stock is priced at a discount to its own history.

How does HRTX's valuation compare to peers?

Heron Therapeutics, Inc. P/E of -10.1x compares to sector median of 22.2x. The discount suggests lower growth expectations or higher risk.

What is HRTX's PEG ratio?

HRTX PEG ratio is N/A. Above 2.0 indicates premium valuation relative to growth rate. Historical P/E data spans 1997-2006.

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HRTX P/E Ratio History (1997–2006)

P/E ratio calculated as closing price divided by trailing 12-month diluted EPS at each quarter end.