Last 22 quarters of trend data · Healthcare · Biotechnology
Quarterly valuation ratios — annualised for comparability. YoY Δ shows same-quarter-prior-year change.
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P/E Ratio → | -2.04 | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| P/S Ratio | 9.56 | 37.73 | 78.26 | 26.59 | 41.15 | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| P/B Ratio | 0.59 | 1.16 | 1.75 | 6.86 | 3.99 | 3.69 | 3.89 | 3.00 | 2.30 | 0.53 | — | — | 0.45 |
| — | -68.4% | -55.0% | +128.8% | +73.8% | +593.3% | — | — | +415.5% | +58.6% | — | — | +48.6% | |
| P/FCF | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBITDA | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBIT | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — |
Quarterly margins and returns. Watch for margin compression across consecutive quarters.
LENZ Therapeutics, Inc.'s operating margin was -2321.7% in Q1 2026, up 100.4 pp QoQ. The trailing four-quarter average of -1308.0% exceeds the current quarter, suggesting the latest result may reflect seasonal weakness or a one-off headwind.
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | 96.3% | 37.6% | 66.9% | 99.0% | 99.6% | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| Operating Margin | -477.5% | -2321.7% | -2422.1% | -151.1% | -337.1% | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| Net Margin | -430.3% | -2182.4% | -2260.5% | -133.6% | -298.2% | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — |
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | -33.6% | -15.6% | -15.0% | -8.3% | -7.5% | -7.4% | -6.0% | -5.0% | -5.2% | -31.6% | — | -24.4% | -5.9% |
| — | -111.8% | -148.8% | -66.7% | -42.8% | +76.6% | — | +79.5% | +10.9% | -214.1% | — | -224.1% | +22.8% | |
| ROA | -31.5% | -14.3% | -13.9% | -7.8% | -7.1% | -7.0% | -5.8% | -4.8% | -4.9% | -11.6% | -29.2% | -10.0% | -4.9% |
| — | -104.4% | -141.3% | -63.0% | -45.9% | +39.4% | +80.2% | +51.9% | +1.0% | -63.0% | -490.2% | -38.9% | +32.2% | |
| ROIC | -30.7% | -13.8% | -13.5% | -8.4% | -7.4% | -7.1% | -6.3% | -6.8% | -19.8% | — | — | -80.3% | -6.2% |
| — | -92.5% | -112.9% | -23.3% | +62.3% | — | — | +91.6% | -217.0% | — | — | -1001.8% | +29.0% |
Quarterly solvency trend — watch for debt spikes or covenant pressure.
The current ratio has weakened 55.0% YoY to 10.40x, tightening the short-term liquidity position.
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | 0.00 | 0.00 | 0.00 | 0.00 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.00 | — | — | 0.24 |
| — | -84.4% | -81.8% | -67.6% | -42.2% | +107.1% | — | — | -96.3% | -81.9% | — | — | +887.4% | |
| Debt / EBITDA | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| Current Ratio | 13.80 | 10.40 | 13.80 | 12.69 | 20.54 | 23.09 | 20.36 | 28.63 | 23.23 | 11.47 | 3.63 | 5.34 | 20.47 |
| — | -55.0% | -32.2% | -55.7% | -11.6% | +101.3% | +460.7% | +436.5% | +13.5% | -39.1% | -26.0% | -75.8% | -24.4% | |
| Quick Ratio | 13.80 | 10.26 | 13.80 | 12.63 | 20.54 | 23.09 | 20.36 | 28.63 | 23.23 | 11.47 | 3.63 | 5.34 | 20.47 |
| — | -55.5% | -32.2% | -55.9% | -11.6% | +101.3% | +460.7% | +436.5% | +13.5% | -39.1% | -26.0% | -75.8% | -24.4% | |
| Interest Coverage | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — |
Includes 30+ ratios · 22 years · Updated daily
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Quick answers to the most common questions about buying LENZ stock.
LENZ Therapeutics, Inc.'s current P/E is -2.0x. Quarterly P/E ratios can vary due to seasonal revenue patterns and one-time charges.
LENZ Therapeutics, Inc.'s current operating margin is -477.5%. Margins have been compressing over recent quarters. Quarterly margins are particularly useful for identifying trend inflections that annual data smooths over.
Quarterly financial ratios reveal short-term trend shifts — margin compression, debt spikes, or valuation re-ratings — that annual figures smooth over. They're essential for active investors tracking LENZ Therapeutics, Inc.'s business trajectory between earnings reports.