Lyell Immunopharma, Inc. (LYEL) Stock Price History
Historical prices from 2021 to 2026
- 1M
- -22.8%
- 3M
- -36.5%
- YTD
- -56.0%
- 1Y
- +33.0%
- 3Y
- -40.3%
- 5Y
- -47.6%
Loading 10-year price history...
LYEL Historical Performance
LYEL Annual Returns
Year-by-year price performance · 2021–2026
- 2021 annual price return
- -54.2%
- 2022 annual price return
- -54.9%
- 2023 annual price return
- -42.3%
- 2024 annual price return
- -69.7%
- 2025 annual price return
- +138.6%
- 2026 annual price return
- -17.2%
LYEL Stock Price Trajectory (2021–2026)
As of June 23, 2026, Lyell Immunopharma, Inc. (LYEL) trades at $11.97, representing a +33.0% return over the past year. The stock has delivered a -96.1% total return over five years (-47.6% CAGR), reflecting challenging market conditions.
The stock reached its all-time high of $396.80 on September 7, 2021. From this peak, LYEL has corrected -97.0%, currently trading 42% below its 200-day moving average, suggesting potential weakness.
When compared to Healthcare sector peers FATE (+72.7% 1Y), ADCT (-64.0% 1Y), and CABA (+64.2% 1Y), LYEL has underperformed the peer group average. Compare LYEL vs FATE →
LYEL Historical Price Data · from 2021
Rows 1–50 of 1,259| Date | Open | High | Low | Close | Volume | Change % |
|---|---|---|---|---|---|---|
| 2026-06-22 | 13.06 | 13.06 | 11.67 | 11.97 | 175K | -6.04% |
| 2026-06-18 | 12.73 | 13.22 | 12.24 | 12.74 | 358K | +1.76% |
| 2026-06-17 | 12.48 | 13.02 | 12.35 | 12.52 | 162K | +0.64% |
| 2026-06-16 | 13.36 | 13.49 | 12.03 | 12.44 | 194K | -8.19% |
| 2026-06-15 | 13.78 | 13.96 | 13.27 | 13.55 | 82K | +0.37% |
| 2026-06-12 | 13.67 | 13.80 | 13.08 | 13.50 | 93K | -1.60% |
| 2026-06-11 | 13.22 | 14.14 | 12.83 | 13.72 | 142K | +3.78% |
| 2026-06-10 | 12.64 | 13.46 | 12.64 | 13.22 | 142K | +4.09% |
| 2026-06-09 | 12.50 | 13.03 | 12.17 | 12.70 | 99K | +3.17% |
| 2026-06-08 | 12.20 | 12.47 | 11.85 | 12.31 | 122K | +2.84% |
| 2026-06-05 | 12.99 | 12.99 | 11.70 | 11.97 | 96K | -8.28% |
| 2026-06-04 | 12.59 | 13.13 | 11.95 | 13.05 | 126K | +3.82% |
| 2026-06-03 | 14.86 | 14.87 | 12.37 | 12.57 | 408K | -15.58% |
| 2026-06-02 | 17.15 | 17.16 | 14.71 | 14.89 | 116K | -13.18% |
| 2026-06-01 | 17.23 | 17.65 | 16.74 | 17.15 | 81K | -1.04% |
| 2026-05-29 | 16.55 | 17.41 | 16.55 | 17.33 | 65K | +2.97% |
| 2026-05-28 | 16.77 | 17.08 | 16.41 | 16.83 | 57K | +0.60% |
| 2026-05-27 | 16.43 | 17.21 | 16.02 | 16.73 | 84K | +2.20% |
| 2026-05-26 | 17.46 | 17.65 | 16.09 | 16.37 | 130K | -6.24% |
| 2026-05-22 | 17.19 | 17.69 | 17.19 | 17.46 | 53K | +0.92% |
| 2026-05-21 | 16.59 | 17.54 | 16.21 | 17.30 | 70K | +0.46% |
| 2026-05-20 | 16.26 | 17.30 | 16.00 | 17.22 | 80K | +6.76% |
| 2026-05-19 | 16.00 | 16.43 | 15.49 | 16.13 | 117K | -2.30% |
| 2026-05-18 | 18.12 | 18.12 | 16.41 | 16.51 | 96K | -7.87% |
| 2026-05-15 | 18.56 | 18.73 | 17.43 | 17.92 | 107K | -5.78% |
| 2026-05-14 | 19.25 | 19.49 | 18.84 | 19.02 | 37K | -1.14% |
| 2026-05-13 | 19.10 | 19.41 | 18.64 | 19.24 | 39K | -0.05% |
| 2026-05-12 | 19.07 | 19.55 | 18.68 | 19.25 | 53K | +0.26% |
| 2026-05-11 | 18.91 | 20.70 | 18.55 | 19.20 | 97K | -0.67% |
| 2026-05-08 | 19.93 | 20.38 | 19.14 | 19.33 | 61K | -3.64% |
| 2026-05-07 | 20.94 | 21.23 | 19.53 | 20.06 | 52K | -3.79% |
| 2026-05-06 | 20.67 | 21.28 | 20.20 | 20.85 | 36K | +1.12% |
| 2026-05-05 | 21.45 | 21.45 | 20.32 | 20.62 | 52K | -0.48% |
| 2026-05-04 | 20.57 | 21.48 | 20.57 | 20.72 | 50K | -0.53% |
| 2026-05-01 | 20.11 | 21.20 | 19.93 | 20.83 | 48K | +5.58% |
| 2026-04-30 | 20.64 | 21.55 | 19.59 | 19.73 | 47K | -4.22% |
| 2026-04-29 | 21.48 | 21.48 | 20.29 | 20.60 | 56K | -4.14% |
| 2026-04-28 | 22.52 | 23.68 | 21.32 | 21.49 | 63K | -5.00% |
| 2026-04-27 | 22.26 | 23.23 | 21.89 | 22.62 | 60K | +0.94% |
| 2026-04-24 | 23.14 | 23.67 | 22.25 | 22.41 | 53K | -5.04% |
| 2026-04-23 | 24.76 | 24.80 | 23.12 | 23.60 | 79K | -4.76% |
| 2026-04-22 | 24.40 | 24.78 | 23.65 | 24.78 | 72K | +3.66% |
| 2026-04-21 | 24.80 | 24.99 | 23.33 | 23.91 | 76K | -3.96% |
| 2026-04-20 | 23.87 | 25.03 | 23.38 | 24.89 | 124K | +3.67% |
| 2026-04-17 | 24.15 | 24.64 | 23.75 | 24.01 | 94K | +1.31% |
| 2026-04-16 | 24.60 | 24.60 | 23.30 | 23.70 | 58K | -0.59% |
| 2026-04-15 | 23.02 | 24.26 | 23.02 | 23.84 | 86K | +2.01% |
| 2026-04-14 | 24.90 | 24.90 | 23.18 | 23.37 | 129K | -5.77% |
| 2026-04-13 | 24.02 | 25.00 | 22.48 | 24.80 | 168K | +10.76% |
| 2026-04-10 | 24.00 | 24.23 | 22.39 | 22.39 | 108K | -6.12% |
Intrinsic Valuation
DCF models, multiple analysis, and analyst estimates.
Historical Returns
10-year return with dividends reinvested.
DCA Calculator
See how regular investing compounds over time.
Peer Comparison
Compare growth, multiples, and margins vs sector.
LYEL — Frequently Asked Questions
Quick answers to the most common questions about buying LYEL stock.
How has LYEL stock performed recently?
LYEL returned +33.0% over the past year, beating its 5-year annualized CAGR of -47.6%. The stock trades below its 200-day moving average, confirming the uptrend.
What is LYEL's all-time high price?
Lyell Immunopharma, Inc. reached $396.80 on 2021-09-07. The 52-week high is $45.00. Current 1-year return of +33.0% places the stock closer to historical peaks.
Where can I download LYEL historical price data?
This page provides LYEL daily OHLCV data with 50-day MA, 200-day MA, and RSI indicators. Data spans 2021-2026, downloadable in CSV format.