65% buyers of institutions opening or closing positions this quarter
8 more new buyers than exits, ownership rose 137.26 percentage points vs the prior quarter, and 1 well-known fund manager in the top 25.
65% buyers of institutions opening or closing positions this quarter
193.7% institutional ownership
StepStone Group LP portfolio allocation
Institutional ownership vs Biotechnology peers
No Form 4 insider transactions on file
Latest positioning in OKUR across 13F flow, ownership shift, marquee holders, and holder-count growth.
Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in OKUR held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | RA CAPITAL MANAGEMENT, L.P. | 4.0M | $16.6M | β | 29.241% | 0.18% |
| 2 | ACORN CAPITAL ADVISORS, LLC | 2.8M | $11.8M | 0.0% | 20.768% | 3.34% |
| 3 | StepStone Group LP | 2.7M | $11.0M | +440.8% | 19.458% | 5.31% |
| 4 | ADAR1 Capital Management, LLC | 2.4M | $10.1M | +140.1% | 17.808% | 0.59% |
| 5 | Prosight Management, LP | 2.2M | $8.9M | +163.7% | 15.756% | 1.46% |
| 6 | BVF INC/IL | 2.0M | $8.2M | β | 14.473% | 0.26% |
| 7 | Vivo Capital, LLC | 1.9M | $8.0M | β | 14.098% | 0.67% |
| 8 | Vestal Point Capital, LP | 1.8M | $7.6M | +189.7% | 13.455% | 0.21% |
| 9 | Foresite Capital Management VI LLC | 1.4M | $6.0M | β | 10.573% | 1.30% |
| 10 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 1.2M | $5.0M | β | 8.811% | 0.01% |
| 11 | Sio Capital Management, LLC | 1.1M | $4.5M | β | 7.891% | 0.64% |
| 12 | VANGUARD CAPITAL MANAGEMENT LLC | 582K | $2.4M | β | 4.260% | 0.00% |
| 13 | NEA Management Company, LLC | 479K | $2.0M | 0.0% | 3.500% | 0.11% |
| 14 | Rosalind Advisors, Inc. | 444K | $1.8M | -39.3% | 3.245% | 0.74% |
| 15 | RENAISSANCE TECHNOLOGIES LLC | 377K | $1.6M | +52.5% | 2.759% | 0.00% |
| 16 | Carlyle Group Inc. | 270K | $1.1M | 0.0% | 1.974% | 0.01% |
| 17 | Affinity Asset Advisors, LLC | 241K | $998K | β | 1.762% | 0.05% |
| 18 | Sofinnova Investments, Inc. | 142K | $587K | β | 1.036% | 0.02% |
| 19 | Stonepine Capital Management, LLC | 133K | $549K | β | 0.970% | 0.22% |
| 20 | Shay Capital LLC | 132K | $547K | -83.1% | 0.967% | 0.05% |
| 21 | CANTOR FITZGERALD, L. P. | 100K | $414K | -77.5% | 0.731% | 0.01% |
| 22 | GEODE CAPITAL MANAGEMENT, LLC | 99K | $409K | +27.5% | 0.722% | 0.00% |
| 23 | Rangeley Capital, LLC | 95K | $393K | -34.5% | 0.695% | 0.38% |
| 24 | Aisling Capital Management LP | 89K | $367K | 0.0% | 0.648% | 0.08% |
| 25 | BlackRock, Inc. | 50K | $205K | -5.9% | 0.363% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in OKUR β a direct measure of their conviction.
Filings activity in OKUR during Q1 2026, grouped by how each filer changed its position.
7 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 49 | +20% | 193.68% | +137.26 pp | $113M | +254% |
| Q4 2025 | 41 | 2.4% | 56.42% | +6.82 pp | $32M | +14% |
| Q3 2025 | 42 | 16% | 49.60% | +3.97 pp | $28M | +8.7% |
| Q2 2025 | 50 | +4.2% | 45.63% | 33.27 pp | $26M | 44% |
| Q1 2025 | 48 | 5.9% | 78.90% | 97.09 pp | $46M | 54% |
| Q4 2024 | 51 | +5000% | 175.99% | +175.98 pp | $99M | +1822408% |
| Q3 2024 | 1 | β | 0.01% | β | $0M | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
No recent Form 4 insider transactions on file for OKUR.
Quick answers to the most common questions about buying OKUR stock.
Based on Q1 2026 13F filings, institutional ownership of OnKure Therapeutics, Inc. stands at 193.7%, held across 49 reporting institutions.
RA CAPITAL MANAGEMENT, L.P. is the largest reported institutional holder of OKUR, with approximately 3,998,333 shares worth $0.02B as of Q1 2026.
Yes β 1 widely-followed marquee investor appear among the top 25 institutional holders of OKUR, including RENAISSANCE TECHNOLOGIES LLC.
Our composite Smart Money Score for OKUR is 64 out of 100 (Bullish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
17 institutions opened new positions in OKUR during Q1 2026, while 9 fully exited. 23 added to existing positions and 8 trimmed.
OKUR institutional ownership rose by 137.26 percentage points quarter-over-quarter, with a net change of +8 holders.
The top 10 institutions account for 82.7% of all reported 13F value in OKUR, and the top 25 account for 98.6%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.