OnKure Therapeutics, Inc. (OKUR) delivered a return of 47.37% over the past year. Since OKUR does not currently pay dividends, the total return equals the price-only return.

A $10,000 investment in OnKure Therapeutics, Inc. one year ago would be worth $14,737 today, representing a gain of $4,737.

OnKure Therapeutics, Inc. (OKUR) does not currently pay dividends. Many growth-focused companies reinvest profits back into the business rather than distributing them as dividends. For OKUR, the total return equals the price-only return.

Yes, OnKure Therapeutics, Inc. (OKUR) outperformed the S&P 500 by 24.51 percentage points over the past year. OKUR delivered a total return of 47.37%, compared to the S&P 500's 22.86%. This 24.51pp alpha means investors in OKUR earned more than a passive S&P 500 index fund.

OnKure Therapeutics, Inc. (OKUR) experienced a maximum drawdown of -41.56% over the past year, declining from its peak on 2026-04-30 to its trough on 2026-05-18. The stock has not yet fully recovered to its prior peak. Maximum drawdown measures the worst peak-to-trough decline and is an important risk metric for investors.

Here are OnKure Therapeutics, Inc. (OKUR)'s long-term returns with dividends reinvested. Over 10 years, the total return is -97.2% (-30.1% CAGR) — $10,000 would have grown to $280. Over 20 years: -97.2% total return (-16.4% CAGR) — $10,000 → $280. Over 30 years: -97.2% total return (-11.2% CAGR) — $10,000 → $280. Long-term investors benefit from compounding: dividends buy additional shares, which generate their own dividends, creating an exponential growth effect.

OnKure Therapeutics, Inc.'s best calendar year was 2023 with a total return of -34.7%. Its worst year was 2022 with a total return of -73.7%. This range shows the volatility investors should expect — the difference between the best and worst year is 39.0 percentage points.