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PACBPacific Biosciences of California, Inc.
$1.47$457M
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PACB logo

Pacific Biosciences of California, Inc.

PACB
NASDAQ · Medical Devices
$1.47
At close - Sep 22, 4:00 PM EDT - USD
Market Cap$457M
P/E-0.8x
52W High$2.73
Volume7.84M
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q2

Negative Equity and Persistent Cash Burn Threaten Viability

Pacific Biosciences faces a critical financial crossroads, with its balance sheet deteriorating into negative equity of -$33.2M and a cash position of only $61.0M against $706.1M in total debt as of 2026Q2. While gross margins have recovered from a trough to 3...

GrowthContracting
ProfitabilityWeak
ValuationReview
TechnicalsWeak
Explore valuation models
MARKET ACTION

PACB price & volume

Price trend, volume and key moving averages

Launch Terminal
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Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

5/12 Beats

EPS beat 5 of last 12 quarters

02

Valuation risk

-102% Peers

P/E is 102% below peer median

03

Market leadership

RS 46 · Lag

Laggard (Underperforming 54% of market)

04

Weak Trend

Below 200DMA

Price < 200DMA

Next CatalystEstimated earnings · Nov 3

Market performance

Price History →

Trailing total returns as of 9/23/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
PACB-20.11%
S&P 500 (^GSPC)+13.20%
1-Year Return
PACB+13.95%
S&P 500 (^GSPC)+15.98%
3-Year Return
PACB-83.56%
S&P 500 (^GSPC)+86.51%
5-Year Return
PACB-94.61%
S&P 500 (^GSPC)+83.94%

Growth & profitability

Annual revenue & EPS trend
Revenue
$160M+3.9% YoY
Net income
-$546M-76.3% YoY
Free cash flow
-$114M+46.3% YoY
Operating margin
-348.5%-40.5 pts YoY
ROIC (TTM)-45.8%
Avg ROIC 5Y-
ROE (TTM)-213.5%
Piotroski Score3 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate5/12 (42%)
Revenue Beat Rate4/12 (33%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q3 2026Latest
Aug 3, 2026
-$0.14-9.4%
vs -$0.13
$39M-9.1%
vs $43M
Q2 2026
May 7, 2026
-$0.03+82.4%
vs -$0.17
$37M-6.9%
vs $40M
Q1 2026
Feb 12, 2026
-$0.12+36.8%
vs -$0.19
$45M+3.7%
vs $43M
Q4 2025
Nov 5, 2025
-$0.12+25.0%
vs -$0.16
$38M-13.8%
vs $45M
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

5 Stories
Zacks Investment Research·Sep 10, 2026
Pacific Biosciences of California (PACB) Dips More Than Broader Market: What You Should Know

Pacific Biosciences of California (PACB) closed at $1.27 in the latest trading session, marking a -1.55% move from the prior day.

Zacks Investment Research·Sep 4, 2026
Pacific Biosciences (PACB) Up 11.6% Since Last Earnings Report: Can It Continue?

Pacific Biosciences (PACB) reported earnings 30 days ago. What's next for the stock?

GlobeNewsWire·Sep 3, 2026
PacBio to Participate in the Morgan Stanley 24ᵗʰ Annual Global Healthcare Conference

MENLO PARK, Calif., Sept. 03, 2026 (GLOBE NEWSWIRE) -- PacBio (NASDAQ: PACB), a leading developer of high-quality, highly accurate sequencing solutions, announced today that management will participate in a fireside chat at the Morgan Stanley 24th Annual Global Healthcare Conference on Tuesday, September 15, 2026, at 4:50 PM ET in New York, New York.

Zacks Investment Research·Sep 2, 2026
PACB Cuts 2026 Outlook as Clinical Adoption Faces Its Crucial Test

PacBio cut its 2026 revenue outlook as weaker instrument demand and a slower SPRQ-Nx transition raised the stakes for clinical adoption.

Filtered for Pacific Biosciences of California, Inc.More Headlines
04

Compare before deciding

Benchmark PACB against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Pacific Biosciences of California, Inc. (PACB)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
PACB logoPACBPacific Biosciences of California, Inc.Current
$1.47$456.58M-0.813.89%-341.47%-213.45%—
ILMN logoILMNIllumina, Inc.
$247.46$37.44B45.41-0.78%18.36%31.08%—
BFLY logoBFLYButterfly Network, Inc.
$9.93$2.64B-32.0318.96%-66.74%-38.36%—
CDNA logoCDNACareDx, Inc
$56.49$2.92B-141.2313.79%24.23%32.81%—
TMO logoTMOThermo Fisher Scientific Inc.
$658.52$244.72B37.123.91%15.06%13.33%—
DHR logoDHRDanaher Corporation
$221.12$155.44B43.872.9%15.95%7.66%—

Compare PACB vs Peers

Pacific Biosciences of California, Inc. (PACB) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs ILMN

Most directly comparable listed peer for PACB.

Scale Benchmark

vs TMO

Larger-name benchmark to compare PACB against a more recognizable public peer.

Peer Set

Compare Top 5

vs ILMN, BFLY, CDNA, TMO

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

PACB SEC Filings & Documents

Pacific Biosciences of California, Inc. (PACB) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Aug 5, 2026·SEC

Material company update

Jul 9, 2026·SEC

Material company update

Jun 4, 2026·SEC

10-K Annual Reports

3
FY 2026

Feb 25, 2026·SEC

FY 2025

Mar 17, 2025·SEC

FY 2024

Feb 28, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

Aug 6, 2026·SEC

FY 2026

May 8, 2026·SEC

FY 2025

Nov 6, 2025·SEC

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PACB Frequently Asked Questions

Pacific Biosciences of California, Inc. (PACB) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Pacific Biosciences of California, Inc.'s revenue?

Pacific Biosciences of California, Inc. (PACB) reported $159.3M in revenue for fiscal year 2025. This represents a 17577% increase from $0.9M in 2008.

How fast is Pacific Biosciences of California, Inc. growing?

Pacific Biosciences of California, Inc. (PACB) grew revenue by 3.9% over the past year. Growth has been modest.

Is PACB profitable?

Pacific Biosciences of California, Inc. (PACB) reported a net loss of $131.4M for fiscal year 2025.

Dividend & Returns
What is PACB's return on equity?

Pacific Biosciences of California, Inc. (PACB) has a return on equity (ROE) of -213.5%. Negative ROE indicates the company is unprofitable.

What is Pacific Biosciences of California, Inc.'s free cash flow?

Pacific Biosciences of California, Inc. (PACB) had negative free cash flow of $171.2M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in PACB back in 2008?

Total return calculator · dividends reinvested · 18+ years of data

See returns →