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PACBPacific Biosciences of California, Inc.
$2.26$702M
Overview & Tools
OverviewChart Terminal ↗Visualize
Valuation & Forecasts
Valuation ModelsEstimatesDCF Model
Price & Analyst Data
Analyst TargetsPrice History
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PACB logo

Pacific Biosciences of California, Inc.

PACB
NASDAQ · Life Science Tools
$2.26
At close - Nov 6, 4:00 PM EST - USD
Market Cap$702M
P/E-5.4x
52W High$3.44
Volume9.53M
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q2

Negative Equity and Persistent Cash Burn Threaten Viability

Pacific Biosciences faces a critical financial crossroads, with its balance sheet deteriorating into negative equity of -$33.2M and a cash position of only $61.0M against $706.1M in total debt as of 2026Q2.

GrowthContracting
ProfitabilityWeak
ValuationReview
TechnicalsStrong
Explore valuation models
MARKET ACTION

PACB price & volume

Price trend, volume and key moving averages

Launch Terminal
Loading chart...
Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

5/12 Beats

EPS beat 5 of last 12 quarters

02

Valuation risk

-116% Peers

P/E is 116% below peer median

03

Market leadership

RS 95 · Leader

High momentum (Outperforming 95% of market)

04

Strong Uptrend

Strong Trend

Price > 20DMA > 50DMA > 200DMA

Next CatalystEstimated earnings · Feb 4

Market performance

Price History →

Trailing total returns as of 11/8/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
PACB+22.55%
S&P 500 (^GSPC)+7.63%
1-Year Return
PACB+26.69%
S&P 500 (^GSPC)+9.69%
3-Year Return
PACB-66.84%
S&P 500 (^GSPC)+61.45%
5-Year Return
PACB-92.35%
S&P 500 (^GSPC)+50.45%

Growth & profitability

Annual revenue & EPS trend
Revenue FY25
$160M+3.9% YoY
Net income FY25
-$546M-76.3% YoY
Free cash flow FY25
-$114M+46.3% YoY
Operating margin FY25
-348.5%-40.5 pts YoY
ROIC (FY25)-45.8%
Avg ROIC 5Y-26.2%
ROE (TTM)-2618.5%
Piotroski Score3 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate5/12 (42%)
Revenue Beat Rate4/12 (33%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q4 2026Latest
Nov 4, 2026
-$0.11+18.2%
vs -$0.13
$41M+3.2%
vs $39M
Q3 2026
Aug 5, 2026
-$0.14+0.0%
vs -$0.14
$39M-2.3%
vs $40M
Q2 2026
May 7, 2026
-$0.03+82.4%
vs -$0.17
$37M-6.9%
vs $40M
Q1 2026
Feb 12, 2026
-$0.12+36.8%
vs -$0.19
$45M+3.7%
vs $43M
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

4 Stories
GlobeNewsWire·Oct 27, 2026
PacBio to Participate in Upcoming Investor Conferences

MENLO PARK, Calif., Oct. 27, 2026 (GLOBE NEWSWIRE) -- PacBio (NASDAQ: PACB), a leading developer of high-quality, highly accurate sequencing solutions, announced today that management will be participating in the following upcoming investor conferences:

Zacks Investment Research·Oct 27, 2026
Here's Why You Should Hold PacBio Stock in Your Portfolio for Now

PACB's growing clinical adoption, advanced sequencing technologies and rising consumables sales support growth, but funding headwinds and margin pressures persist.

Zacks Investment Research·Oct 22, 2026
Pacific Biosciences of California (PACB) Declines More Than Market: Some Information for Investors

The latest trading day saw Pacific Biosciences of California (PACB) settling at $2.06, representing a -3.74% change from its previous close.

GlobeNewsWire·Oct 19, 2026
PacBio and Verily Health Announce Multi-Year Strategic Collaboration to Scale Long-Read Genomics for Biomedical AI

Verily Pre will connect PacBio HiFi Sequencing with governed cloud analysis, multimodal health data and AI-ready research workflows Verily Pre will connect PacBio HiFi Sequencing with governed cloud analysis, multimodal health data and AI-ready research workflows

Filtered for Pacific Biosciences of California, Inc.More Headlines
04

Compare before deciding

Benchmark PACB against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Pacific Biosciences of California, Inc. (PACB)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
PACB logoPACBPacific Biosciences of California, Inc.Current
$2.26$701.96M-5.363.89%-81.31%-2618.51%—
ILMN logoILMNIllumina, Inc.
$213.13$32.25B36.67-0.78%19.72%31.45%—
BFLY logoBFLYButterfly Network, Inc.
$6.37$1.7B-31.6118.96%-43.56%-28.22%—
CDNA logoCDNACareDx, Inc
$78.56$4.06B33.5813.79%25.86%34.08%—
TMO logoTMOThermo Fisher Scientific Inc.
$694.76$258.19B36.393.91%14.96%13.3%0.24%
DHR logoDHRDanaher Corporation
$230.25$161.86B37.582.9%16.91%8.18%0.54%

Compare PACB vs Peers

Pacific Biosciences of California, Inc. (PACB) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs ILMN

Most directly comparable listed peer for PACB.

Scale Benchmark

vs TMO

Larger-name benchmark to compare PACB against a more recognizable public peer.

Peer Set

Compare Top 5

vs ILMN, BFLY, CDNA, TMO

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

PACB SEC Filings & Documents

Pacific Biosciences of California, Inc. (PACB) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Aug 5, 2026·SEC

Material company update

Jul 9, 2026·SEC

Material company update

Jun 4, 2026·SEC

10-K Annual Reports

3
FY 2026

Feb 25, 2026·SEC

FY 2025

Mar 17, 2025·SEC

FY 2024

Feb 28, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

Aug 6, 2026·SEC

FY 2026

May 8, 2026·SEC

FY 2025

Nov 6, 2025·SEC

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PACB Frequently Asked Questions

Pacific Biosciences of California, Inc. (PACB) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Pacific Biosciences of California, Inc.'s revenue?

Pacific Biosciences of California, Inc. (PACB) reported $161.4M in revenue over the trailing twelve months. Revenue was $160.0M in fiscal year 2025. That is 17659% more than the $0.9M of fiscal year 2008.

How fast is Pacific Biosciences of California, Inc. growing?

Pacific Biosciences of California, Inc. (PACB) grew revenue by 4.4% over the trailing twelve months, compared with the twelve months before.

Is PACB profitable?

No. Pacific Biosciences of California, Inc. (PACB) reported a net loss of $131.2M over the trailing twelve months.

Dividend & Returns
What is PACB's return on equity?

Pacific Biosciences of California, Inc. (PACB) had a return on equity (ROE) of -2618.5% over the trailing twelve months. A negative ROE means the company lost money over the period.

What is Pacific Biosciences of California, Inc.'s free cash flow?

Pacific Biosciences of California, Inc. (PACB) had negative free cash flow of $143.4M over the trailing twelve months.

What if you invested $1,000 in PACB back in 2008?

Total return calculator · dividends reinvested · 18+ years of data

See returns →