Phio Pharmaceuticals Corp. (PHIO) fundamental analysis — strengths, weaknesses & financial health based on data analysis
* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.
Phio Pharmaceuticals Corp. (PHIO) stock price & volume — 10-year historical chart
Phio Pharmaceuticals Corp. (PHIO) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR
Phio Pharmaceuticals Corp. (PHIO) competitors in RNA and Genome Editing Developers — business model, growth, and fundamentals comparison
Phio Pharmaceuticals Corp. (PHIO) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.
Phio Pharmaceuticals Corp. (PHIO) annual income statement — 10-year revenue, gross profit & net income history
| Line item | Dec'17 | Dec'18 | Dec'19 | Dec'20 | Dec'21 | Dec'22 | Dec'23 | Dec'24 | Dec'25 | TTM |
|---|---|---|---|---|---|---|---|---|---|---|
| Sales/Revenue | 15K | 138K | 21K | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Revenue Growth % | -21.05% | 820% | -84.78% | -100% | - | - | - | - | - | - |
| Cost of Goods Sold | 5.37M | 4.33M | 0 | 3.72M | 8.89M | 7.01M | 6.33M | 3.64M | 0 | 1.08M |
| COGS % of Revenue | 35800% | 3134.78% | - | - | - | - | - | - | - | - |
| Gross Profit | -5.36M▲ 0% | -4.19M▲ 21.8% | 21K▲ 100.5% | -3.72M▼ 17795.2% | -8.89M▼ 139.1% | -7.01M▲ 21.1% | -6.33M▲ 9.7% | -3.64M▲ 42.5% | 0▲ 100.0% | -1.08M▲ 0% |
| Gross Margin % | -35700% | -3034.78% | 100% | - | - | - | - | - | - | - |
| Gross Profit Growth % | 0.76% | 21.79% | 100.5% | -17795.24% | -139.13% | 21.09% | 9.7% | 42.47% | 100% | - |
| Operating Expenses | 9.38M | 7.5M | 9.01M | 5.08M | 4.63M | 4.45M | 4.49M | 3.74M | 9.22M | 7.28M |
| OpEx % of Revenue | 62540% | 5436.23% | 42895.24% | - | - | - | - | - | - | - |
| Selling, General & Admin | 4.01M | 3.18M | 4.71M | 5.08M | 4.63M | 4.45M | 4.29M | 3.74M | 4.6M | 4.23M |
| SG&A % of Revenue | 26740% | 2301.45% | 22419.05% | - | - | - | - | - | - | - |
| Research & Development | 5.37M | 4.33M | 4.3M | 3.72M | 8.89M | 7.01M | 6.33M | 3.64M | 4.62M | 4.13M |
| R&D % of Revenue | 35800% | 3134.78% | 20476.19% | - | - | - | - | - | - | - |
| Other Operating Expenses | 4.7M | 4K | 0 | -3.72M | -8.89M | -7.01M | -6.13M | -3.64M | 0 | -1000K |
| Operating Income | -14.06M▲ 0% | -7.36M▲ 47.6% | -8.99M▼ 22.0% | -8.79M▲ 2.2% | -13.51M▼ 53.7% | -11.46M▲ 15.2% | -10.82M▲ 5.6% | -7.39M▲ 31.8% | 0▲ 100.0% | -8.36M▲ 0% |
| Operating Margin % | -93746.67% | -5336.23% | -42795.24% | - | - | - | - | - | - | - |
| Operating Income Growth % | -55.98% | 47.63% | -22.04% | 2.16% | -53.66% | 15.17% | 5.57% | 31.75% | 100% | - |
| EBITDA | -13.99M | -7.28M | -8.92M | -8.72M | -13.44M | -11.39M | -10.64M | -7.38M | 0 | -8.21M |
| EBITDA Margin % | -93280% | -5277.54% | -42476.19% | - | - | - | - | - | - | - |
| EBITDA Growth % | -56.13% | 47.95% | -22.48% | 2.23% | -54.06% | 15.22% | 6.59% | 30.59% | 100% | -10.78% |
| D&A (Non-Cash Add-back) | 70K | 81K | 67K | 72K | 75K | 71K | 184K | 2K | 0 | 2.5K |
| EBIT | -14.07M | -7.36M | -8.99M | -8.79M | -13.51M | -11.46M | -10.83M | -7.39M | 0 | -8.1M |
| Net Interest Income | -1K | 0 | 0 | 0 | 0 | 0 | 0 | 231K | 0 | 588K |
| Interest Income | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 231K | 0 | 588K |
| Interest Expense | 1K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Income/Expense | -11K | 4K | 79K | -1K | 224K | -18K | -2K | 237K | 0 | 407K |
| Pretax Income | -14.07M▲ 0% | -7.36M▲ 47.7% | -8.91M▼ 21.0% | -8.79M▲ 1.3% | -13.29M▼ 51.1% | -11.48M▲ 13.6% | -10.83M▲ 5.7% | -7.15M▲ 34.0% | -8.7M▼ 21.7% | -7.95M▲ 0% |
| Pretax Margin % | -93820% | -5333.33% | -42419.05% | - | - | - | - | - | - | - |
| Income Tax | -1.62M | 4K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Effective Tax Rate % | 11.52% | -0.05% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% |
| Net Income | -12.45M▲ 0% | -7.36M▲ 40.9% | -8.91M▼ 21.0% | -8.79M▲ 1.3% | -13.29M▼ 51.1% | -11.48M▲ 13.6% | -10.83M▲ 5.7% | -7.15M▲ 34.0% | -8.7M▼ 21.7% | -7.95M▲ 0% |
| Net Margin % | -83013.33% | -5333.33% | -42419.05% | - | - | - | - | - | - | - |
| Net Income Growth % | -38.45% | 40.89% | -21.03% | 1.28% | -51.09% | 13.6% | 5.7% | 33.96% | -21.65% | -7.2% |
| Net Income (Continuing) | -12.45M | -7.36M | -8.91M | -8.79M | -13.29M | -11.48M | -10.83M | -7.15M | -8.7M | -7.95M |
| Discontinued Operations | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| EPS (Diluted) | -32801.22▲ 0% | -6218.35▲ 81.0% | -2074.18▲ 66.6% | -207.25▲ 90.0% | -111.32▲ 46.3% | -89.61▲ 19.5% | -46.76▲ 47.8% | -0.91▲ 98.1% | -1.45▼ 59.3% | -1.45▲ 0% |
| EPS Growth % | 58.63% | 81.04% | 66.64% | 90.01% | 46.29% | 19.5% | 47.82% | 98.05% | -59.34% | -294107.81% |
| EPS (Basic) | -32801.22 | -6218.35 | -2074.18 | -207.25 | -111.32 | -89.61 | -46.87 | -0.91 | -1.45 | - |
| Diluted Shares Outstanding | 380 | 1.18K | 4.26K | 42.43K | 118.68K | 126.16K | 231.51K | 787.47K | 5.98M | 5.47M |
| Basic Shares Outstanding | 380 | 1.18K | 4.26K | 42.43K | 118.68K | 126.16K | 231K | 787.47K | 5.98M | 5.47M |
| Dividend Payout Ratio | - | - | - | - | - | - | - | - | - | - |
Phio Pharmaceuticals Corp. (PHIO) balance sheet — assets, liabilities & shareholders' equity
| Line item | Dec'17 | Dec'18 | Dec'19 | Dec'20 | Dec'21 | Dec'22 | Dec'23 | Dec'24 | Dec'25 | TTM |
|---|---|---|---|---|---|---|---|---|---|---|
| Total Current Assets | 3.83M | 15.15M | 7.3M | 15.16M | 24.73M | 12.45M | 9.32M | 5.74M | 21.48M | 11.49M |
| Cash & Short-Term Investments | 3.58M | 14.88M | 6.93M | 14.24M | 24.06M | 11.78M | 8.49M | 5.38M | 21.03M | 10.71M |
| Cash Only | 3.58M | 14.88M | 6.93M | 14.24M | 24.06M | 11.78M | 8.49M | 5.38M | 21.03M | 10.71M |
| Short-Term Investments | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Accounts Receivable | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Days Sales Outstanding | - | - | - | - | - | - | - | - | - | - |
| Inventory | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Days Inventory Outstanding | - | - | - | - | - | - | - | - | - | - |
| Other Current Assets | 50K | 50K | 50K | 50K | 50K | 50K | 832K | 354K | 445K | 788K |
| Total Non-Current Assets | 266K | 172K | 739K | 575K | 443K | 368K | 42K | 2K | 11K | 12K |
| Property, Plant & Equipment | 248K | 172K | 721K | 557K | 416K | 344K | 39K | 2K | 11K | 12K |
| Fixed Asset Turnover | 0.06x | 0.80x | 0.03x | - | - | - | - | - | - | 0.00x |
| Goodwill | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Intangible Assets | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Long-Term Investments | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Current Assets | 18K | 0 | 18K | 18K | 27K | 24K | 3K | 0 | 0 | 0 |
| Total Assets | 4.1M▲ 0% | 15.32M▲ 273.9% | 8.04M▼ 47.5% | 15.74M▲ 95.8% | 25.17M▲ 59.9% | 12.81M▼ 49.1% | 9.36M▼ 26.9% | 5.74M▼ 38.7% | 21.49M▲ 274.5% | 11.51M▲ 0% |
| Asset Turnover | 0.00x | 0.01x | 0.00x | - | - | - | - | - | - | 0.00x |
| Asset Growth % | -69.41% | 273.89% | -47.53% | 95.78% | 59.92% | -49.09% | -26.92% | -38.72% | 274.47% | 266.95% |
| Total Current Liabilities | 2.27M | 1.74M | 1.88M | 2.2M | 3.07M | 1.94M | 1.63M | 1.01M | 435K | 516K |
| Accounts Payable | 511K | 550K | 809K | 728K | 283K | 779K | 657K | 253K | 435K | 516K |
| Days Payables Outstanding | 34.73 | 46.41 | - | 71.51 | 11.62 | 40.55 | 37.87 | 25.35 | - | 121.36 |
| Short-Term Debt | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Deferred Revenue (Current) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Current Liabilities | 0 | 0 | 551K | 722K | 0 | 19K | 720K | 731K | 435K | -732K |
| Current Ratio | 1.69x | 8.69x | 3.88x | 6.91x | 8.06x | 6.42x | 5.71x | 5.65x | 49.37x | 49.37x |
| Quick Ratio | 1.69x | 8.69x | 3.88x | 6.91x | 8.06x | 6.42x | 5.71x | 5.65x | 49.37x | 49.37x |
| Cash Conversion Cycle | - | - | - | - | - | - | - | - | - | - |
| Total Non-Current Liabilities | 0 | 0 | 411K | 526K | 170K | 35K | 0 | 0 | 905K | 1.15M |
| Long-Term Debt | 0 | 0 | 0 | 231K | 0 | 0 | 0 | 0 | 0 | 0 |
| Capital Lease Obligations | 0 | 0 | 411K | 295K | 170K | 35K | 0 | 0 | 0 | 0 |
| Deferred Tax Liabilities | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Current Liabilities | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 905K | 1.15M |
| Total Liabilities | 2.27M | 1.74M | 2.29M | 2.72M | 3.24M | 1.97M | 1.63M | 1.01M | 1.34M | 1.67M |
| Total Debt | 0 | 0 | 518K | 642K | 295K | 170K | 35K | 0 | 0 | 0 |
| Net Debt | -3.58M | -14.88M | -6.42M | -13.6M | -23.76M | -11.61M | -8.46M | -5.38M | -21.03M | -10.71M |
| Debt / Equity | - | - | 0.09x | 0.05x | 0.01x | 0.02x | 0.00x | - | - | 0.00x |
| Debt / EBITDA | - | - | - | - | - | - | - | - | - | -0.00x |
| Net Debt / EBITDA | - | - | - | - | - | - | - | - | - | 1.30x |
| Interest Coverage | -14062.00x | - | - | - | - | - | - | - | - | - |
| Total Equity | 1.83M▲ 0% | 13.58M▲ 640.8% | 5.75M▼ 57.7% | 13.02M▲ 126.5% | 21.93M▲ 68.5% | 10.84M▼ 50.6% | 7.73M▼ 28.7% | 4.72M▼ 38.9% | 20.15M▲ 326.6% | 9.84M▲ 0% |
| Equity Growth % | -83.11% | 640.75% | -57.67% | 126.46% | 68.49% | -50.57% | -28.69% | -38.9% | 326.57% | 344.75% |
| Book Value per Share | 4828.51 | 11471.85 | 1348.54 | 306.77 | 184.79 | 85.92 | 33.39 | 6.00 | 3.37 | 1.80 |
| Total Shareholders' Equity | 1.83M | 13.58M | 5.75M | 13.02M | 21.93M | 10.84M | 7.73M | 4.72M | 20.15M | 9.84M |
| Common Stock | 0 | 2K | 1K | 1K | 0 | 0 | 0 | 0 | 1K | 1K |
| Retained Earnings | -78.55M | -85.91M | -94.82M | -103.61M | -116.9M | -128.38M | -139.21M | -146.36M | -155.05M | -152.68M |
| Treasury Stock | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Accumulated OCI | -900K | -981K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Phio Pharmaceuticals Corp. (PHIO) cash flow — operating, investing & free cash flow history
| Line item | Dec'17 | Dec'18 | Dec'19 | Dec'20 | Dec'21 | Dec'22 | Dec'23 | Dec'24 | Dec'25 | TTM |
|---|---|---|---|---|---|---|---|---|---|---|
| Cash from Operations | -9.51M | -7.52M | -8.64M | -8.8M | -11.86M | -12.13M | -10.75M | -7.11M | -8.7M | -8.7M |
| Operating CF Margin % | -63426.67% | -5449.28% | -41166.67% | - | - | - | - | - | - | - |
| Operating CF Growth % | -22.6% | 20.96% | -14.96% | -1.82% | -34.72% | -2.29% | 11.38% | 33.84% | -22.3% | 29.05% |
| Net Income | -12.45M | -7.36M | -8.91M | -8.79M | -13.29M | -11.48M | -10.83M | -7.15M | 0 | -7.95M |
| Depreciation & Amortization | 70K | 81K | 67K | 72K | 75K | 193K | 184K | 35K | 3K | 44K |
| Stock-Based Compensation | 314K | 282K | 300K | 136K | 480K | 414K | 303K | 147K | 481K | 255K |
| Deferred Taxes | -1.62M | 0 | 0 | 0 | -233K | 0 | 0 | 0 | 0 | 0 |
| Other Non-Cash Items | 4.71M | 405K | 109K | 111K | 117K | 0 | 126K | -6K | -9.18M | -51K |
| Working Capital Changes | -530K | -523K | -213K | -327K | 990K | -1.26M | -536K | -138K | 0 | 434K |
| Change in Receivables | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Change in Inventory | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Change in Payables | -608K | 39K | 259K | -81K | -445K | 496K | -122K | -404K | 183K | 332K |
| Cash from Investing | -103K | -5K | -72K | -19K | -51K | -121K | -5K | 8K | -12K | -4K |
| Capital Expenditures | -203K | -5K | -72K | -19K | -51K | -121K | -5K | -1K | -12K | -13K |
| CapEx % of Revenue | 1353.33% | 3.62% | 342.86% | - | - | - | - | - | - | - |
| Acquisitions | 100K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Investments | - | - | - | - | - | - | - | - | - | - |
| Other Investing | 100K | 0 | 0 | 0 | 0 | 0 | 0 | 9K | 0 | 9K |
| Cash from Financing | 292K | 18.82M | 772K | 16.13M | 21.72M | -26K | 7.41M | 4M | 23.64M | 12.59M |
| Debt Issued (Net) | 0 | 0 | -6K | 204K | 0 | 0 | 0 | 0 | 0 | 0 |
| Equity Issued (Net) | 292K | 1000K | 709K | 1000K | 1000K | 2K | 1000K | 1000K | 0 | 3.04M |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | 0 | 0 | 0 | -15K | 0 | 0 | -11K | -1K | 0 | 0 |
| Other Financing | 0 | 0 | 69K | 3.85M | 2.15M | -28K | -26K | -5K | 23.64M | -31K |
| Net Change in Cash | -9.32M▲ 0% | 11.3M▲ 221.2% | -7.95M▼ 170.3% | 7.31M▲ 192.0% | 9.81M▲ 34.2% | -12.28M▼ 225.1% | -3.34M▲ 72.8% | -3.11M▲ 7.0% | 15.65M▲ 603.5% | 5.32M▲ 0% |
| Free Cash Flow | -9.72M▲ 0% | -7.53M▲ 22.6% | -8.72M▼ 15.8% | -8.82M▼ 1.2% | -11.91M▼ 35.0% | -12.25M▼ 2.9% | -10.75M▲ 12.2% | -7.11M▲ 33.9% | -8.71M▼ 22.5% | -7.28M▲ 0% |
| FCF Margin % | -64780% | -5452.9% | -41509.52% | - | - | - | - | - | - | - |
| FCF Growth % | -25.15% | 22.56% | -15.84% | -1.19% | -35.01% | -2.86% | 12.21% | 33.86% | -22.45% | 10.2% |
| FCF per Share | -25596.65 | -6357.76 | -2045.09 | -207.89 | -100.34 | -97.10 | -46.45 | -9.03 | -1.46 | -1.46 |
| FCF Conversion (FCF/Net Income) | 0.76x | 1.02x | 0.97x | 1.00x | 0.89x | 1.06x | 0.99x | 0.99x | 1.00x | 0.92x |
| Interest Paid | 0 | 0 | 0 | 0 | 0 | 0 | 11K | 0 | 0 | 0 |
| Taxes Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Phio Pharmaceuticals Corp. (PHIO) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios
| Metric | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | TTM |
|---|---|---|---|---|---|---|---|---|---|---|
| Return on Equity (ROE) | -196.28% | -95.52% | -92.19% | -93.73% | -76.04% | -70.06% | -116.6% | -114.83% | -69.95% | -86.38% |
| Return on Invested Capital (ROIC) | - | - | - | - | - | - | - | - | - | 757.02% |
| Gross Margin | -35700% | -3034.78% | 100% | - | - | - | - | - | - | - |
| Net Margin | -83013.33% | -5333.33% | -42419.05% | - | - | - | - | - | - | - |
| Debt / Equity | - | - | 0.09x | 0.05x | 0.01x | 0.02x | 0.00x | - | - | 0.00x |
| Interest Coverage | -14062.00x | - | - | - | - | - | - | - | - | - |
| FCF Conversion | 0.76x | 1.02x | 0.97x | 1.00x | 0.89x | 1.06x | 0.99x | 0.99x | 1.00x | 0.92x |
| Revenue Growth | -21.05% | 820% | -84.78% | -100% | - | - | - | - | - | - |
Phio Pharmaceuticals Corp. (PHIO) stock FAQ — growth, dividends, profitability & financials explained
Phio Pharmaceuticals Corp. (PHIO) grew revenue by 0.0% over the past year. Growth has been modest.
Phio Pharmaceuticals Corp. (PHIO) reported a net loss of $8.0M for fiscal year 2025.
Phio Pharmaceuticals Corp. (PHIO) has a return on equity (ROE) of -69.9%. Negative ROE indicates the company is unprofitable.
Phio Pharmaceuticals Corp. (PHIO) had negative free cash flow of $7.3M in fiscal year 2025, likely due to heavy capital investments.
Phio Pharmaceuticals Corp. (PHIO) financial analysis — history, returns, DCA and operating performance tools
Historical returns with dividends reinvested
Dollar cost averaging vs lump sum
Yield, growth, payout safety & DRIP
EPS trends, net income & profitability
Long-term charts & historical price data
Sales growth patterns & revenue breakdown
30 years of market, efficiency and balance-sheet ratios
DCF intrinsic value, peer multiples & estimates