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PHIO
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PHIOPhio Pharmaceuticals Corp.
$0.80$9M
Overview & Tools
OverviewChart Terminal ↗Visualize
Valuation & Forecasts
Valuation ModelsEstimatesDCF Model
Price & Analyst Data
Analyst TargetsPrice History
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P/E HistoryRevenue HistoryEarnings HistoryDividend HistoryTotal Return
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PHIO logo

Phio Pharmaceuticals Corp.

PHIO
NASDAQ · Cell & Gene Therapy
$0.80
At close - Nov 6, 4:00 PM EST - USD
Market Cap$9M
P/E-0.6x
52W High$1.88
Volume75.62K
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q1

Persistent Clinical Burn Outpaces Capital Reserves

Phio Pharmaceuticals remains a pre-commercial biotechnology entity characterized by a total absence of revenue and an escalating R&D burn rate that reached $2.8 million in 2026Q1.

GrowthContracting
ProfitabilityNegative
ValuationReview
TechnicalsWeak
Explore valuation models
MARKET ACTION

PHIO price & volume

Price trend, volume and key moving averages

Launch Terminal
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Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

6/12 Beats

EPS beat 6 of last 12 quarters

02

Valuation risk

-102% Peers

P/E is 102% below peer median

03

Market leadership

RS 27 · Lag

Laggard (Underperforming 73% of market)

04

Weak Trend

Below 200DMA

Price < 200DMA

Next CatalystEstimated earnings · Feb 5

Market performance

Price History →

Trailing total returns as of 11/8/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
PHIO-26.49%
S&P 500 (^GSPC)+7.63%
1-Year Return
PHIO-45.86%
S&P 500 (^GSPC)+9.69%
3-Year Return
PHIO-92.70%
S&P 500 (^GSPC)+68.86%
5-Year Return
PHIO-99.56%
S&P 500 (^GSPC)+56.88%

Growth & profitability

Annual revenue & EPS trend
Revenue FY25
-
Net income FY25
-$9M-21.7% YoY
Free cash flow FY25
-$8M-12.3% YoY
Operating margin FY25
-
ROIC (FY25)-
Avg ROIC 5Y-
ROE (TTM)-101.5%
Piotroski Score3 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate6/12 (60%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q4 2026Latest
Nov 5, 2026
-$0.36+0.0%
vs -$0.36
—
vs —
Q3 2026
Aug 6, 2026
-$0.36+0.0%
vs -$0.36
—
vs —
Q2 2026
May 7, 2026
-$0.34-41.7%
vs -$0.24
—
vs —
Q2 2026
Mar 5, 2026
-$0.15+55.9%
vs -$0.34
—
vs —
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

4 Stories
Newsfile Corp·Oct 19, 2026
Phio Pharmaceuticals Announces Participation in the Renmark Financial Communications Live Virtual Non-Deal Roadshow Series

Live Presentation and Q&A: Tuesday, October 20, 2026 12 PM EDT King of Prussia, Pennsylvania--(Newsfile Corp. - October 19, 2026) - Phio Pharmaceuticals Corp. (NASDAQ: PHIO) is a clinical-stage siRNA biopharmaceutical company developing therapeutics using its proprietary INTASYL® gene silencing technology to eliminate cancer. Phio Pharmaceuticals announced today that Robert Bitterman, CEO and Chairman of the Board, will present an overview of the Company's INTASYL® siRNA therapeutic platform, including its lead clinical candidate PH-762 for the treatment of cutaneous carcinomas.

Newsfile Corp·Oct 13, 2026
Phio Pharmaceuticals Announces Successful Completion of First Commercial-Scale cGMP Batch of PH-762 Drug Substance

King of Prussia, Pennsylvania--(Newsfile Corp. - October 13, 2026) - Phio Pharmaceuticals Corp. (NASDAQ: PHIO), a clinical-stage biotechnology company developing

Defense World·Oct 11, 2026
Phio Pharmaceuticals Highlights 85% Response Rate as PH-762 Nears Phase 2b

Phio Pharmaceuticals (NASDAQ: PHIO) is advancing its lead immuno-oncology candidate, PH-762, as a potential neoadjuvant treatment for cutaneous squamous cell carcinoma, President and Chief Executive Officer Robert Bitterman said during a Virtual Investor Conferences presentation. The company's approach centers on INTASYL, a self-delivering short interfering RNA platform designed to silence specific genes. PH-762 targets PD-1, a

Newsfile Corp·Oct 6, 2026
Phio Pharmaceuticals to Present at The Global Markets Virtual Forum October 8, 2026

Phio invites individual and institutional investors as well as advisors and analysts, to attend online at www.VirtualInvestorConference.comKing of Prussia, Pennsylvania--(Newsfile

Filtered for Phio Pharmaceuticals Corp.More Headlines
04

Compare before deciding

Benchmark PHIO against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Phio Pharmaceuticals Corp. (PHIO)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
PHIO logoPHIOPhio Pharmaceuticals Corp.Current
$0.80$9.31M-0.64——-101.48%—
SRPT logoSRPTSarepta Therapeutics, Inc.
$17.82$1.88B127.9315.58%0.75%1.04%—
ARWR logoARWRArrowhead Pharmaceuticals, Inc.
$58.16$8.19B-26.0623258.15%-47.79%-60.05%—
ALNY logoALNYAlnylam Pharmaceuticals, Inc.
$155.94$20.82B7.9065.19%54.34%159.72%—
NTLA logoNTLAIntellia Therapeutics, Inc.
$11.35$1.27B-3.7316.92%-805.75%-64.73%—
BEAM logoBEAMBeam Therapeutics Inc.
$26.41$2.72B-25.82120.01%-73.04%-9.69%—

Compare PHIO vs Peers

Phio Pharmaceuticals Corp. (PHIO) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs SRPT

Most directly comparable listed peer for PHIO.

Scale Benchmark

vs TMO

Larger-name benchmark to compare PHIO against a more recognizable public peer.

Peer Set

Compare Top 5

vs SRPT, ARWR, ALNY, NTLA

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

PHIO SEC Filings & Documents

Phio Pharmaceuticals Corp. (PHIO) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Aug 6, 2026·SEC

Material company update

Jul 21, 2026·SEC

Material company update

May 7, 2026·SEC

10-K Annual Reports

2
FY 2026

Mar 5, 2026·SEC

FY 2025

Mar 31, 2025·SEC

10-Q Quarterly Reports

6
FY 2026

Aug 6, 2026·SEC

FY 2026

May 7, 2026·SEC

FY 2025

Nov 13, 2025·SEC

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PHIO Frequently Asked Questions

Phio Pharmaceuticals Corp. (PHIO) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
Is PHIO profitable?

No. Phio Pharmaceuticals Corp. (PHIO) reported a net loss of $14.7M over the trailing twelve months.

Dividend & Returns
What is PHIO's return on equity?

Phio Pharmaceuticals Corp. (PHIO) had a return on equity (ROE) of -101.5% over the trailing twelve months. A negative ROE means the company lost money over the period.

What is Phio Pharmaceuticals Corp.'s free cash flow?

Phio Pharmaceuticals Corp. (PHIO) had negative free cash flow of $12.4M over the trailing twelve months.

What if you invested $1,000 in PHIO back in 2011?

Total return calculator · dividends reinvested · 15+ years of data

See returns →