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SKYE logoSkye Bioscience, Inc.(SKYE)Earnings, Financials & Key Ratios

SKYE•NASDAQ
Price updated Jun 19, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryOphthalmology Therapies and Delivery
AboutSkye Bioscience, Inc., a biopharmaceutical company, discovers, develops, and commercializes cannabinoid-based molecules for the treatment of infectious diseases. The company's lead product candidate is SBI-100, which is in Phase I trials for the treatment of glaucoma and ocular hypertension. It is also developing SBI-200 that is in preclinical trials to treat and manage various eye diseases, including uveitis, dry eye syndrome, macular degeneration and diabetic retinopathy. The company was formerly known as Emerald Bioscience, Inc. and changed its name to Skye Bioscience, Inc. in January 2021. Skye Bioscience, Inc. was founded in 2012 and is headquartered in San Diego, California.Show more
  • Revenue$0
  • EBITDA-$57M-92.1%
  • Net Income-$56M-110.5%
  • EPS (Diluted)-1.41-93.2%
  • ROE-126.85%-57.6%

SKYE Key Insights

Skye Bioscience, Inc. (SKYE) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Company is almost debt free
  • ✓Trading at only 1.4x book value

✗Weaknesses

  • ✗Profits declining 53.5% over 5 years
  • ✗Weak Piotroski F-Score: 1/9
  • ✗Weak momentum: RS Rating 20 (bottom 20%)
  • ✗Trading more than 30% below 52-week high
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

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SKYE Price & Volume

Skye Bioscience, Inc. (SKYE) stock price & volume — 10-year historical chart

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SKYE Growth Metrics

Skye Bioscience, Inc. (SKYE) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-75.59%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-75.61%

Return on Capital

10 Years-652.22%
5 Years-758.77%
3 Years-781.81%
Last Year-131.39%

SKYE Recent Earnings

Skye Bioscience, Inc. (SKYE) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 4/12 qtrs (40%)
Q2 2026Latest
May 12, 2026
Metric
Actual
Est
EPS
$0.32-10.3%
$0.29
Rev
—
—
Q2 2026
Mar 10, 2026
Metric
Actual
Est
EPS
$0.36-21.2%
$0.30
Rev
—
—
Q4 2025
Nov 10, 2025
Metric
Actual
Est
EPS
$0.32+3.0%
$0.33
Rev
—
—
Q3 2025
Aug 7, 2025
Metric
Actual
Est
EPS
$0.44-29.4%
$0.34
Rev
—
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 12, 2026
$0.32vs $0.29-10.3%
—
Q2 2026Mar 10, 2026
$0.36vs $0.30-21.2%
—
Q4 2025Nov 10, 2025
$0.32vs $0.33+3.0%
—
Q3 2025Aug 7, 2025
$0.44vs $0.34-29.4%
—
Based on last 12 quarters of dataView full earnings history →

SKYE Peer Comparison

Skye Bioscience, Inc. (SKYE) competitors in Ophthalmology Therapies and Delivery — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
Institutional Holdings
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
ATAI logoATAIAtai Beckley N.VDirect Competitor1.49B4.06-1.4012.28%-190.19%-366.21%0.01
CMPS logoCMPSCOMPASS Pathways plcDirect Competitor1.2B12.53-4.07-151.02%
MNMD logoMNMDMind Medicine (MindMed) Inc.Direct Competitor2.04B20.69-10.04-102.48%
SNDL logoSNDLSNDL Inc.Direct Competitor368.06M1.42-33.382.82%-1.17%-1%0.15
CRBP logoCRBPCorbus Pharmaceuticals Holdings, Inc.Direct Competitor103.54M8.26-1.40-70.89%0.01
YCBD logoYCBDcbdMD, Inc.Product Competitor7.56M0.72-0.66-1.5%-13.29%-33.59%107.70
NRXP logoNRXPNRx Pharmaceuticals, Inc.Product Competitor68.62M3.97-2.96-10.7%
JAZZ logoJAZZJazz Pharmaceuticals plcSupply Chain14.09B224.66-38.474.88%0.66%0.71%1.26

Compare SKYE vs Peers

Skye Bioscience, Inc. (SKYE) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs ATAI

Most directly comparable listed peer for SKYE.

Scale Benchmark

vs ABBV

Larger-name benchmark to compare SKYE against a more recognizable public peer.

Peer Set

Compare Top 5

vs ATAI, CMPS, MNMD, SNDL

SKYE Income Statement

Skye Bioscience, Inc. (SKYE) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Sales/Revenue
0000000000
Revenue Growth %
----------
Cost of Goods Sold
8.04K1.54K1.46K1.87K0000723.35K172.89K
COGS % of Revenue
----------
Gross Profit
-8.04K▲ 0%
-1.54K▲ 80.8%
-1.46K▲ 5.3%
-1.87K▼ 28.0%
0▲ 100.0%
0▲ 0%
0▲ 0%
0▲ 0%
-723.35K▲ 0%
-172.89K▲ 0%
Gross Margin %
----------
Gross Profit Growth %
46.11%80.79%5.31%-28.04%100%-----
Operating Expenses
3.86M4.69M6.63M6.29M7.85M18.31M34.74M30.19M57.44M58.91M
OpEx % of Revenue
----------
Selling, General & Admin
3.55M4.36M4.39M4.34M4.92M6.09M7.85M17.73M15.8M15.98M
SG&A % of Revenue
----------
Research & Development
311.3K329.97K2.24M1.94M2.93M6.01M5.82M18.7M42.36M42.93M
R&D % of Revenue
----------
Other Operating Expenses
002K006.21M21.06M-6.23M-723.35K0
Operating Income
-3.86M▲ 0%
-4.69M▼ 21.6%
-6.63M▼ 41.3%
-6.29M▲ 5.2%
-7.85M▼ 24.8%
-18.31M▼ 133.3%
-34.74M▼ 89.7%
-30.19M▲ 13.1%
-58.16M▼ 92.6%
-59.08M▲ 0%
Operating Margin %
----------
Operating Income Growth %
13.69%-21.61%-41.34%5.19%-24.78%-133.34%-89.69%13.08%-92.64%-
EBITDA
-4.62M-4.69M-6.63M-6.29M-7.81M-18.2M-34.61M-29.89M-57.44M-58.36M
EBITDA Margin %
----------
EBITDA Growth %
-3.63%-1.59%-41.35%5.19%-24.28%-132.89%-90.2%13.63%-92.15%-65.08%
D&A (Non-Cash Add-back)
-759K1.54K1.46K1.87K34.13K115K124.25K298.64K723.35K718.86K
EBIT
-3.09M-19.1M2.04M-5.85M-7.75M-18.81M-36.74M-25.59M-58.16M-57.49M
Net Interest Income
0-94.68K-1M-706.36K-767.51K-644.76K-806.3K2.3M1.88M974.6K
Interest Income
0842629319.01K99.97K3.26M1.88M976.8K
Interest Expense
66794.76K1M706.38K767.51K663.77K906.27K967.6K02.2K
Other Income/Expense
766.53K-14.5M7.69M-270K-672.37K-1.16M-2.91M3.64M2.24M1.75M
Pretax Income
-3.09M▲ 0%
-19.19M▼ 520.5%
1.05M▲ 105.5%
-6.56M▼ 722.9%
-8.52M▼ 29.9%
-19.47M▼ 128.6%
-37.64M▼ 93.3%
-26.56M▲ 29.4%
-55.92M▼ 110.6%
-57.33M▲ 0%
Pretax Margin %
----------
Income Tax
1.6K1.64K1.6K1.6K2.1K6.74K3.6K10.07K5.4K3.4K
Effective Tax Rate %
-0.05%-0.01%0.15%-0.02%-0.02%-0.03%-0.01%-0.04%-0.01%-0.01%
Net Income
-3.09M▲ 0%
-19.19M▼ 520.4%
1.05M▲ 105.5%
-6.56M▼ 723.7%
-8.52M▼ 29.9%
-19.48M▼ 128.6%
-37.64M▼ 93.2%
-26.57M▲ 29.4%
-55.92M▼ 110.5%
-57.33M▲ 0%
Net Margin %
----------
Net Income Growth %
2.64%-520.36%105.48%-723.67%-29.89%-128.6%-93.23%29.43%-110.5%-75.59%
Net Income (Continuing)
-3.09M-19.19M1.05M-6.56M-8.52M-19.48M-37.64M-26.57M-55.92M-57.33M
Discontinued Operations
0000000000
Minority Interest
0000000000
EPS (Diluted)
-25.62▲ 0%
-36.51▼ 42.5%
1.98▲ 105.4%
-7.46▼ 476.8%
-5.00▲ 33.0%
-8.77▼ 75.4%
-5.37▲ 38.8%
-0.73▲ 86.4%
-1.41▼ 93.2%
-1.44▲ 0%
EPS Growth %
35.79%-42.51%105.42%-476.77%32.98%-75.4%38.77%86.41%-93.15%-75.61%
EPS (Basic)
-25.62-36.511.98-7.11-5.00-8.77-5.37-0.73-1.41-
Diluted Shares Outstanding
120.77K525.78K532.01K925.68K1.63M2.22M7.01M36.49M39.66M39.68M
Basic Shares Outstanding
120.77K525.78K532.01K922.99K1.63M2.22M7.01M36.49M39.66M39.68M
Dividend Payout Ratio
----------

SKYE Balance Sheet

Skye Bioscience, Inc. (SKYE) balance sheet — assets, liabilities & shareholders' equity

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Total Current Assets
555.81K1.95M1.99M2.66M9.61M8.94M11.65M70.83M27.09M18.57M
Cash & Short-Term Investments
259.95K1.85M1.83M2.47M8.98M1.24M1.26M68.42M25.74M17.11M
Cash Only
259.95K1.85M1.83M2.47M8.98M1.24M1.26M68.42M5.88M8.15M
Short-Term Investments
0000000019.85M8.96M
Accounts Receivable
0000074.12K158.24K5.07K10.47K0
Days Sales Outstanding
----------
Inventory
0000000000
Days Inventory Outstanding
----------
Other Current Assets
4.43K7.12K12.09K4.84K61.44K6.74M9.64M207.21K1.35M1.46M
Total Non-Current Assets
1.41K3.44K1.98K7.34K242.99K167.35K289.57K1.94M1.22M849.77K
Property, Plant & Equipment
1.41K3.44K1.98K7.34K234.68K159.04K281.26K1.88M1.17M813.86K
Fixed Asset Turnover
---------0.00x
Goodwill
0000000000
Intangible Assets
0000000000
Long-Term Investments
0000000000
Other Non-Current Assets
00008.31K8.31K8.31K53.91K53.91K35.91K
Total Assets
557.22K▲ 0%
1.96M▲ 251.2%
2M▲ 2.0%
2.67M▲ 33.8%
9.86M▲ 268.9%
9.11M▼ 7.5%
11.94M▲ 31.1%
72.76M▲ 509.4%
28.31M▼ 61.1%
19.42M▲ 0%
Asset Turnover
---------0.00x
Asset Growth %
72.32%251.23%2.02%33.8%268.87%-7.55%31.05%509.39%-61.09%-220.66%
Total Current Liabilities
805.97K15.94M970.82K787.2K3.91M12.12M13.9M4.34M8.21M10.4M
Accounts Payable
100.92K15.6K139.81K381.37K900.01K1.79M956.75K569.25K2.03M3.94M
Days Payables Outstanding
4.58K3.69K34.9K74.36K----1.03K6.34K
Short-Term Debt
235K0064.06K1.97M1.9M4.37M0189.65K60.98K
Deferred Revenue (Current)
0000000000
Other Current Liabilities
271.71K15.74M410.6K38.57K435.57K7.48M969.62K549.15K5.98M6.41M
Current Ratio
0.69x0.12x2.05x3.38x2.46x0.74x0.84x16.32x3.30x1.78x
Quick Ratio
0.69x0.12x2.05x3.38x2.46x0.74x0.84x16.32x3.30x1.78x
Cash Conversion Cycle
----------
Total Non-Current Liabilities
551.32K1.58M477.87K1.43M78.7K0171.23K273.16K84K0
Long-Term Debt
01.36M387.07K1.43M000084K0
Capital Lease Obligations
000078.7K0171.23K273.16K0172.49K
Deferred Tax Liabilities
0000000000
Other Non-Current Liabilities
551.32K219.45K90.8K0000000
Total Liabilities
1.36M17.52M1.45M2.22M3.99M12.12M14.07M4.61M8.29M10.4M
Total Debt
235K1.36M387.07K1.5M2.14M1.98M4.62M455.59K273.65K60.98K
Net Debt
-24.95K-492.41K-1.44M-971.61K-6.85M738K3.36M-67.96M-5.61M-8.09M
Debt / Equity
--0.71x3.32x0.36x--0.01x0.01x0.01x
Debt / EBITDA
----------0.00x
Net Debt / EBITDA
---------0.14x
Interest Coverage
-4635.68x-201.53x2.04x-8.29x-10.10x-28.34x-40.54x-26.45x--26144.82x
Total Equity
-800.08K▲ 0%
-15.56M▼ 1845.1%
548.06K▲ 103.5%
450.79K▼ 17.7%
5.86M▲ 1200.9%
-3.01M▼ 151.3%
-2.13M▲ 29.1%
68.15M▲ 3296.9%
20.02M▼ 70.6%
9.01M▲ 0%
Equity Growth %
44.86%-1845.09%103.52%-17.75%1200.88%-151.3%29.13%3296.88%-70.62%-252.1%
Book Value per Share
-6.63-29.601.030.493.61-1.35-0.301.870.500.23
Total Shareholders' Equity
-800.08K-15.56M548.06K450.79K5.86M-3.01M-2.13M68.15M20.02M9.01M
Common Stock
33.62K133.91K182.9K288.07K476.11K3.65K12.35K30.98K33.38K35.13K
Retained Earnings
-14.03M-33.23M-32.17M-38.73M-47.26M-66.74M-104.38M-130.95M-186.87M-199.38M
Treasury Stock
0000000000
Accumulated OCI
0000000000
Minority Interest
0000000000

SKYE Cash Flow Statement

Skye Bioscience, Inc. (SKYE) cash flow — operating, investing & free cash flow history

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Cash from Operations
-3.3M-3.94M-6.03M-6.05M-6.47M-12.74M-13.95M-25.24M-43.06M-42.43M
Operating CF Margin %
----------
Operating CF Growth %
7.17%-19.55%-52.88%-0.43%-6.95%-96.82%-9.48%-80.89%-70.63%-125.03%
Net Income
-3.09M-19.19M1.05M-6.56M-8.52M-19.48M-37.64M-26.57M-55.92M-57.33M
Depreciation & Amortization
8.04K1.54K1.46K1.87K34.13K115K124.25K298.64K723.35K-176.48M
Stock-Based Compensation
608.68K674.96K680.46K302.74K869.21K629.03K987.51K8.32M7.77M-2.19B
Deferred Taxes
00-8.69M0000000
Other Non-Cash Items
-496.78K14.47M629.29K107.76K497.01K6.76M23.05M-4.66M-360.75K-8.71B
Working Capital Changes
-323.85K100.19K295.71K94.19K646.94K-761.9K-469.31K-2.63M4.73M7.47M
Change in Receivables
0000000000
Change in Inventory
0000000000
Change in Payables
-173.73K-85.32K134.21K241.56K518.64K799.74K-701.28K-586.53K1.4M2.08M
Cash from Investing
-19.65K-4.38K0-7.23K-90.87K5.21M6.6M-245.62K-19.5M4.2M
Capital Expenditures
-19.65K-4.38K0-7.23K-90.87K-28.06K-12.55K-1.6M-6.31K0
CapEx % of Revenue
----------
Acquisitions
000005.31M000270.98K
Investments
----------
Other Investing
00000-66.46K6.61M0090.62K
Cash from Financing
3.51M5.54M6M6.7M13.08M-208.79K16.44M83.56M29.57K-41.95K
Debt Issued (Net)
500K2.35M5.2K566.7K0-210.76K4.71M00-71.53K
Equity Issued (Net)
3.01M3.1M1.92M6.09M6.06M1.97K11.73M83.56M29.57K29.57K
Dividends Paid
0000000000
Share Repurchases
0000000000
Other Financing
098.7K4.08M48.53K7.02M0-6.03K5.62K00
Net Change in Cash
195.13K▲ 0%
1.59M▲ 716.6%
-23.37K▼ 101.5%
639.46K▲ 2836.2%
6.51M▲ 918.6%
-7.74M▼ 218.8%
9.09M▲ 217.4%
58.08M▲ 539.1%
-62.53M▼ 207.7%
-38.27M▲ 0%
Free Cash Flow
-3.32M▲ 0%
-3.95M▼ 19.0%
-6.03M▼ 52.7%
-6.06M▼ 0.6%
-6.57M▼ 8.3%
-12.77M▼ 94.5%
-13.96M▼ 9.3%
-26.84M▼ 92.2%
-43.07M▼ 60.5%
-42.43M▲ 0%
FCF Margin %
----------
FCF Growth %
6.91%-18.97%-52.71%-0.55%-8.32%-94.53%-9.34%-92.21%-60.46%99.54%
FCF per Share
-27.47-7.51-11.33-6.55-4.04-5.75-1.99-0.74-1.09-1.07
FCF Conversion (FCF/Net Income)
1.07x0.21x-5.73x0.92x0.76x0.65x0.37x0.95x0.77x0.74x
Interest Paid
023.33K371.42K117.46K44.09K333.55K198.35K433.34K00
Taxes Paid
1.63K1.64K1.6K1.6K1.6K6.74K3.6K5.2K00

SKYE Key Ratios

Skye Bioscience, Inc. (SKYE) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric201720182019202020212022202320242025TTM
Return on Equity (ROE)
--191.95%-1313.72%-269.9%-1364.2%--80.48%-126.85%-217.27%
Return on Invested Capital (ROIC)
-------2123.19%-3192.59%-597.29%-352.62%
Debt / Equity
--0.71x3.32x0.36x--0.01x0.01x0.01x
Interest Coverage
-4635.68x-201.53x2.04x-8.29x-10.10x-28.34x-40.54x-26.45x--26144.82x
FCF Conversion
1.07x0.21x-5.73x0.92x0.76x0.65x0.37x0.95x0.77x0.74x
Related:SKYE Dividend History·SKYE Revenue History·SKYE Price History·SKYE P/E History·SKYE Financial Ratios·SKYE Institutional Holders

SKYE SEC Filings & Documents

Skye Bioscience, Inc. (SKYE) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 15, 2026·SEC

Material company update

Apr 3, 2026·SEC

Material company update

Mar 19, 2026·SEC

10-K Annual Reports

3
FY 2026

Mar 10, 2026·SEC

FY 2025

Mar 20, 2025·SEC

FY 2024

Mar 22, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 11, 2026·SEC

FY 2025

Nov 10, 2025·SEC

FY 2025

Aug 7, 2025·SEC

SKYE Frequently Asked Questions

Skye Bioscience, Inc. (SKYE) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Skye Bioscience, Inc. (SKYE) grew revenue by 0.0% over the past year. Growth has been modest.

Skye Bioscience, Inc. (SKYE) reported a net loss of $57.3M for fiscal year 2025.

Dividend & Returns

Skye Bioscience, Inc. (SKYE) has a return on equity (ROE) of -126.8%. Negative ROE indicates the company is unprofitable.

Skye Bioscience, Inc. (SKYE) had negative free cash flow of $42.4M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in SKYE back in 2012?

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