Biotechnology
Compare Stocks
3 / 10Stock Comparison
ADVM vs OCGN vs EDIT
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
ADVM vs OCGN vs EDIT — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||
|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $96M | $487M | $297M |
| Revenue (TTM) | $0.00 | $4M | $0.00 |
| Net Income (TTM) | $-204M | $-68M | $-160M |
| Gross Margin | 100.0% | 100.0% | — |
| Operating Margin | -139.2% | -14.3% | — |
| Total Debt | $92M | $33M | $18M |
| Cash & Equiv. | $61M | $19M | $147M |
ADVM vs OCGN vs EDIT — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | Dec 25 | Return |
|---|---|---|---|
| Adverum Biotechnolo… (ADVM) | 100 | 2.1 | -97.9% |
| Ocugen, Inc. (OCGN) | 100 | 400.0 | +300.0% |
| Editas Medicine, In… (EDIT) | 100 | 8.9 | -91.1% |
Price return only. Dividends and distributions are not included.
Quick Verdict: ADVM vs OCGN vs EDIT
Each card shows where this stock fits in a portfolio — not just who wins on paper.
ADVM is the clearest fit if your priority is income & stability and long-term compounding.
- beta 1.09
- -89.2% 10Y total return vs OCGN's -98.5%
- Lower volatility, beta 1.09, current ratio 5.73x
OCGN has the current edge in this matchup, primarily because of its strength in growth exposure.
- Rev growth 8.8%, EPS growth -15.0%, 3Y rev CAGR 21.0%
- 8.8% revenue growth vs EDIT's -100.0%
- -15.4% margin vs ADVM's -130.9%
EDIT is the clearest fit if your priority is momentum and efficiency.
- +127.8% vs ADVM's +45.3%
- -74.2% ROA vs ADVM's -282.3%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 8.8% revenue growth vs EDIT's -100.0% | |
| Quality / Margins | -15.4% margin vs ADVM's -130.9% | |
| Stability / Safety | Beta 1.09 vs EDIT's 2.52 | |
| Dividends | Tie | None of these 3 stocks pay a meaningful dividend |
| Momentum (1Y) | +127.8% vs ADVM's +45.3% | |
| Efficiency (ROA) | -74.2% ROA vs ADVM's -282.3% |
ADVM vs OCGN vs EDIT — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
ADVM vs OCGN vs EDIT — Financial Metrics
Side-by-side numbers across 3 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
OCGN leads in 2 of 6 categories
ADVM leads 2 • EDIT leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
OCGN leads this category, winning 3 of 5 comparable metrics.
Income & Cash Flow (Last 12 Months)
OCGN and EDIT operate at a comparable scale, with $4M and $0 in trailing revenue. OCGN is the more profitable business, keeping -15.4% of every revenue dollar as net income compared to ADVM's -130.9%. On growth, ADVM holds the edge at -100.0% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||
|---|---|---|---|
| RevenueTrailing 12 months | $0 | $4M | $0 |
| EBITDAEarnings before interest/tax | -$205M | -$61M | $0 |
| Net IncomeAfter-tax profit | -$204M | -$68M | -$160M |
| Free Cash FlowCash after capex | -$138M | -$57M | -$166M |
| Gross MarginGross profit ÷ Revenue | +100.0% | +100.0% | — |
| Operating MarginEBIT ÷ Revenue | -139.2% | -14.3% | — |
| Net MarginNet income ÷ Revenue | -130.9% | -15.4% | — |
| FCF MarginFCF ÷ Revenue | -92.8% | -13.0% | — |
| Rev. Growth (YoY)Latest quarter vs prior year | -100.0% | -125.3% | -151.6% |
| EPS Growth (YoY)Latest quarter vs prior year | -56.2% | -18.9% | +105.5% |
Valuation Metrics
ADVM leads this category, winning 2 of 3 comparable metrics.
Valuation Metrics
| Metric | |||
|---|---|---|---|
| Market CapShares × price | $96M | $487M | $297M |
| Enterprise ValueMkt cap + debt − cash | $127M | $502M | $168M |
| Trailing P/EPrice ÷ TTM EPS | -0.66x | -6.26x | -1.68x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — |
| Price / SalesMarket cap ÷ Revenue | 96.26x | 110.46x | — |
| Price / BookPrice ÷ Book value/share | 1.22x | — | 9.85x |
| Price / FCFMarket cap ÷ FCF | — | — | — |
Profitability & Efficiency
Evenly matched — ADVM and EDIT each lead in 4 of 8 comparable metrics.
Profitability & Efficiency
ADVM delivers a -189.8% return on equity — every $100 of shareholder capital generates $-190 in annual profit, vs $-26 for OCGN. EDIT carries lower financial leverage with a 0.66x debt-to-equity ratio, signaling a more conservative balance sheet compared to ADVM's 1.30x. On the Piotroski fundamental quality scale (0–9), ADVM scores 3/9 vs EDIT's 1/9, reflecting mixed financial health.
| Metric | |||
|---|---|---|---|
| ROE (TTM)Return on equity | -189.8% | -26.3% | -5.2% |
| ROA (TTM)Return on assets | -2.8% | -123.4% | -74.2% |
| ROICReturn on invested capital | -124.2% | -15.7% | — |
| ROCEReturn on capital employed | -95.1% | -154.7% | — |
| Piotroski ScoreFundamental quality 0–9 | 3 | 2 | 1 |
| Debt / EquityFinancial leverage | 1.30x | — | 0.66x |
| Net DebtTotal debt minus cash | $31M | $15M | -$129M |
| Cash & Equiv.Liquid assets | $61M | $19M | $147M |
| Total DebtShort + long-term debt | $92M | $33M | $18M |
| Interest CoverageEBIT ÷ Interest expense | — | -13.63x | — |
Total Returns (Dividends Reinvested)
OCGN leads this category, winning 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in OCGN five years ago would be worth $1,567 today (with dividends reinvested), compared to $888 for EDIT. Over the past 12 months, EDIT leads with a +127.8% total return vs ADVM's +45.3%. The 3-year compound annual growth rate (CAGR) favors OCGN at 26.1% vs EDIT's -32.0% — a key indicator of consistent wealth creation.
| Metric | |||
|---|---|---|---|
| YTD ReturnYear-to-date | — | +4.3% | +47.8% |
| 1-Year ReturnPast 12 months | +45.3% | +117.5% | +127.8% |
| 3-Year ReturnCumulative with dividends | -46.5% | +100.6% | -68.5% |
| 5-Year ReturnCumulative with dividends | -88.5% | -84.3% | -91.1% |
| 10-Year ReturnCumulative with dividends | -89.2% | -98.5% | -90.0% |
| CAGR (3Y)Annualised 3-year return | -18.8% | +26.1% | -32.0% |
Risk & Volatility
ADVM leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
ADVM is the less volatile stock with a 1.09 beta — it tends to amplify market swings less than EDIT's 2.52 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ADVM currently trades 75.8% from its 52-week high vs OCGN's 52.8% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||
|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.09x | 1.63x | 2.52x |
| 52-Week HighHighest price in past year | $5.75 | $2.73 | $4.54 |
| 52-Week LowLowest price in past year | $1.78 | $0.64 | $1.29 |
| % of 52W HighCurrent price vs 52-week peak | +75.8% | +52.8% | +66.7% |
| RSI (14)Momentum oscillator 0–100 | 58.2 | 35.3 | 57.5 |
| Avg Volume (50D)Average daily shares traded | 0 | 9.4M | 1.6M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: OCGN as "Buy", EDIT as "Buy". Consensus price targets imply 247.2% upside for OCGN (target: $5) vs 98.0% for EDIT (target: $6).
| Metric | |||
|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | Buy |
| Price TargetConsensus 12-month target | — | $5.00 | $6.00 |
| # AnalystsCovering analysts | — | 5 | 25 |
| Dividend YieldAnnual dividend ÷ price | — | — | — |
| Dividend StreakConsecutive years of raises | — | — | — |
| Dividend / ShareAnnual DPS | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% |
OCGN leads in 2 of 6 categories (Income & Cash Flow, Total Returns). ADVM leads in 2 (Valuation Metrics, Risk & Volatility). 1 tied.
ADVM vs OCGN vs EDIT: Key Questions Answered
8 questions · data-driven answers · updated daily
01Is ADVM or OCGN or EDIT a better buy right now?
For growth investors, Ocugen, Inc.
(OCGN) is the stronger pick with 8. 8% revenue growth year-over-year, versus -100. 0% for Editas Medicine, Inc. (EDIT). Analysts rate Ocugen, Inc. (OCGN) a "Buy" — based on 5 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — ADVM or OCGN or EDIT?
Over the past 5 years, Ocugen, Inc.
(OCGN) delivered a total return of -84. 3%, compared to -91. 1% for Editas Medicine, Inc. (EDIT). Over 10 years, the gap is even starker: ADVM returned -89. 2% versus OCGN's -98. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — ADVM or OCGN or EDIT?
By beta (market sensitivity over 5 years), Adverum Biotechnologies, Inc.
(ADVM) is the lower-risk stock at 1. 09β versus Editas Medicine, Inc. 's 2. 52β — meaning EDIT is approximately 131% more volatile than ADVM relative to the S&P 500. On balance sheet safety, Editas Medicine, Inc. (EDIT) carries a lower debt/equity ratio of 66% versus 130% for Adverum Biotechnologies, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — ADVM or OCGN or EDIT?
By revenue growth (latest reported year), Ocugen, Inc.
(OCGN) is pulling ahead at 8. 8% versus -100. 0% for Editas Medicine, Inc. (EDIT). On earnings-per-share growth, the picture is similar: Editas Medicine, Inc. grew EPS 37. 5% year-over-year, compared to -227. 7% for Adverum Biotechnologies, Inc.. Over a 3-year CAGR, OCGN leads at 21. 0% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — ADVM or OCGN or EDIT?
Editas Medicine, Inc.
(EDIT) is the more profitable company, earning 0. 0% net margin versus -130. 9% for Adverum Biotechnologies, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: EDIT leads at 0. 0% versus -139. 2% for ADVM. At the gross margin level — before operating expenses — ADVM leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — ADVM or OCGN or EDIT?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is ADVM or OCGN or EDIT better for a retirement portfolio?
For long-horizon retirement investors, Adverum Biotechnologies, Inc.
(ADVM) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 09)). Editas Medicine, Inc. (EDIT) carries a higher beta of 2. 52 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ADVM: -89. 2%, EDIT: -90. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between ADVM and OCGN and EDIT?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
Find Stocks Like These
Explore pre-built screens for each stock's profile, or build a custom screen to find stocks that outperform all of them.
You Might Also Compare
Based on how these companies actually compete and overlap — not just which sector they're filed under.