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Stock Comparison

ADVM vs OCGN vs EDIT

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
ADVM
Adverum Biotechnologies, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$96M
5Y Perf.-97.9%
OCGN
Ocugen, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$487M
5Y Perf.+300.0%
EDIT
Editas Medicine, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$297M
5Y Perf.-91.1%

ADVM vs OCGN vs EDIT — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
ADVM logoADVM
OCGN logoOCGN
EDIT logoEDIT
IndustryBiotechnologyBiotechnologyBiotechnology
Market Cap$96M$487M$297M
Revenue (TTM)$0.00$4M$0.00
Net Income (TTM)$-204M$-68M$-160M
Gross Margin100.0%100.0%
Operating Margin-139.2%-14.3%
Total Debt$92M$33M$18M
Cash & Equiv.$61M$19M$147M

ADVM vs OCGN vs EDITLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

ADVM
OCGN
EDIT
StockMay 20Dec 25Return
Adverum Biotechnolo… (ADVM)1002.1-97.9%
Ocugen, Inc. (OCGN)100400.0+300.0%
Editas Medicine, In… (EDIT)1008.9-91.1%

Price return only. Dividends and distributions are not included.

Quick Verdict: ADVM vs OCGN vs EDIT

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: OCGN and EDIT are tied at the top with 2 categories each — the right choice depends on your priorities. Editas Medicine, Inc. is the stronger pick specifically for recent price momentum and sentiment and operational efficiency and capital deployment. As sector peers, any of these can serve as alternatives in the same allocation.
ADVM
Adverum Biotechnologies, Inc.
The Income Pick

ADVM is the clearest fit if your priority is income & stability and long-term compounding.

  • beta 1.09
  • -89.2% 10Y total return vs OCGN's -98.5%
  • Lower volatility, beta 1.09, current ratio 5.73x
Best for: income & stability and long-term compounding
OCGN
Ocugen, Inc.
The Growth Play

OCGN has the current edge in this matchup, primarily because of its strength in growth exposure.

  • Rev growth 8.8%, EPS growth -15.0%, 3Y rev CAGR 21.0%
  • 8.8% revenue growth vs EDIT's -100.0%
  • -15.4% margin vs ADVM's -130.9%
Best for: growth exposure
EDIT
Editas Medicine, Inc.
The Momentum Pick

EDIT is the clearest fit if your priority is momentum and efficiency.

  • +127.8% vs ADVM's +45.3%
  • -74.2% ROA vs ADVM's -282.3%
Best for: momentum and efficiency
See the full category breakdown
CategoryWinnerWhy
GrowthOCGN logoOCGN8.8% revenue growth vs EDIT's -100.0%
Quality / MarginsOCGN logoOCGN-15.4% margin vs ADVM's -130.9%
Stability / SafetyADVM logoADVMBeta 1.09 vs EDIT's 2.52
DividendsTieNone of these 3 stocks pay a meaningful dividend
Momentum (1Y)EDIT logoEDIT+127.8% vs ADVM's +45.3%
Efficiency (ROA)EDIT logoEDIT-74.2% ROA vs ADVM's -282.3%

ADVM vs OCGN vs EDIT — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

ADVMAdverum Biotechnologies, Inc.
FY 2024
Reportable Segment
100.0%$1M
OCGNOcugen, Inc.

Segment breakdown not available.

EDITEditas Medicine, Inc.
FY 2025
Reportable Segment
100.0%$41M

ADVM vs OCGN vs EDIT — Financial Metrics

Side-by-side numbers across 3 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLADVMLAGGINGEDIT

Income & Cash Flow (Last 12 Months)

OCGN leads this category, winning 3 of 5 comparable metrics.

OCGN and EDIT operate at a comparable scale, with $4M and $0 in trailing revenue. OCGN is the more profitable business, keeping -15.4% of every revenue dollar as net income compared to ADVM's -130.9%. On growth, ADVM holds the edge at -100.0% YoY revenue growth, suggesting stronger near-term business momentum.

MetricADVM logoADVMAdverum Biotechno…OCGN logoOCGNOcugen, Inc.EDIT logoEDITEditas Medicine, …
RevenueTrailing 12 months$0$4M$0
EBITDAEarnings before interest/tax-$205M-$61M$0
Net IncomeAfter-tax profit-$204M-$68M-$160M
Free Cash FlowCash after capex-$138M-$57M-$166M
Gross MarginGross profit ÷ Revenue+100.0%+100.0%
Operating MarginEBIT ÷ Revenue-139.2%-14.3%
Net MarginNet income ÷ Revenue-130.9%-15.4%
FCF MarginFCF ÷ Revenue-92.8%-13.0%
Rev. Growth (YoY)Latest quarter vs prior year-100.0%-125.3%-151.6%
EPS Growth (YoY)Latest quarter vs prior year-56.2%-18.9%+105.5%
OCGN leads this category, winning 3 of 5 comparable metrics.

Valuation Metrics

ADVM leads this category, winning 2 of 3 comparable metrics.
MetricADVM logoADVMAdverum Biotechno…OCGN logoOCGNOcugen, Inc.EDIT logoEDITEditas Medicine, …
Market CapShares × price$96M$487M$297M
Enterprise ValueMkt cap + debt − cash$127M$502M$168M
Trailing P/EPrice ÷ TTM EPS-0.66x-6.26x-1.68x
Forward P/EPrice ÷ next-FY EPS est.
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple
Price / SalesMarket cap ÷ Revenue96.26x110.46x
Price / BookPrice ÷ Book value/share1.22x9.85x
Price / FCFMarket cap ÷ FCF
ADVM leads this category, winning 2 of 3 comparable metrics.

Profitability & Efficiency

Evenly matched — ADVM and EDIT each lead in 4 of 8 comparable metrics.

ADVM delivers a -189.8% return on equity — every $100 of shareholder capital generates $-190 in annual profit, vs $-26 for OCGN. EDIT carries lower financial leverage with a 0.66x debt-to-equity ratio, signaling a more conservative balance sheet compared to ADVM's 1.30x. On the Piotroski fundamental quality scale (0–9), ADVM scores 3/9 vs EDIT's 1/9, reflecting mixed financial health.

MetricADVM logoADVMAdverum Biotechno…OCGN logoOCGNOcugen, Inc.EDIT logoEDITEditas Medicine, …
ROE (TTM)Return on equity-189.8%-26.3%-5.2%
ROA (TTM)Return on assets-2.8%-123.4%-74.2%
ROICReturn on invested capital-124.2%-15.7%
ROCEReturn on capital employed-95.1%-154.7%
Piotroski ScoreFundamental quality 0–9321
Debt / EquityFinancial leverage1.30x0.66x
Net DebtTotal debt minus cash$31M$15M-$129M
Cash & Equiv.Liquid assets$61M$19M$147M
Total DebtShort + long-term debt$92M$33M$18M
Interest CoverageEBIT ÷ Interest expense-13.63x
Evenly matched — ADVM and EDIT each lead in 4 of 8 comparable metrics.

Total Returns (Dividends Reinvested)

OCGN leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in OCGN five years ago would be worth $1,567 today (with dividends reinvested), compared to $888 for EDIT. Over the past 12 months, EDIT leads with a +127.8% total return vs ADVM's +45.3%. The 3-year compound annual growth rate (CAGR) favors OCGN at 26.1% vs EDIT's -32.0% — a key indicator of consistent wealth creation.

MetricADVM logoADVMAdverum Biotechno…OCGN logoOCGNOcugen, Inc.EDIT logoEDITEditas Medicine, …
YTD ReturnYear-to-date+4.3%+47.8%
1-Year ReturnPast 12 months+45.3%+117.5%+127.8%
3-Year ReturnCumulative with dividends-46.5%+100.6%-68.5%
5-Year ReturnCumulative with dividends-88.5%-84.3%-91.1%
10-Year ReturnCumulative with dividends-89.2%-98.5%-90.0%
CAGR (3Y)Annualised 3-year return-18.8%+26.1%-32.0%
OCGN leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

ADVM leads this category, winning 2 of 2 comparable metrics.

ADVM is the less volatile stock with a 1.09 beta — it tends to amplify market swings less than EDIT's 2.52 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ADVM currently trades 75.8% from its 52-week high vs OCGN's 52.8% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricADVM logoADVMAdverum Biotechno…OCGN logoOCGNOcugen, Inc.EDIT logoEDITEditas Medicine, …
Beta (5Y)Sensitivity to S&P 5001.09x1.63x2.52x
52-Week HighHighest price in past year$5.75$2.73$4.54
52-Week LowLowest price in past year$1.78$0.64$1.29
% of 52W HighCurrent price vs 52-week peak+75.8%+52.8%+66.7%
RSI (14)Momentum oscillator 0–10058.235.357.5
Avg Volume (50D)Average daily shares traded09.4M1.6M
ADVM leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: OCGN as "Buy", EDIT as "Buy". Consensus price targets imply 247.2% upside for OCGN (target: $5) vs 98.0% for EDIT (target: $6).

MetricADVM logoADVMAdverum Biotechno…OCGN logoOCGNOcugen, Inc.EDIT logoEDITEditas Medicine, …
Analyst RatingConsensus buy/hold/sellBuyBuy
Price TargetConsensus 12-month target$5.00$6.00
# AnalystsCovering analysts525
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

OCGN leads in 2 of 6 categories (Income & Cash Flow, Total Returns). ADVM leads in 2 (Valuation Metrics, Risk & Volatility). 1 tied.

Best OverallAdverum Biotechnologies, In… (ADVM)Leads 2 of 6 categories
Loading custom metrics...

ADVM vs OCGN vs EDIT: Key Questions Answered

8 questions · data-driven answers · updated daily

01

Is ADVM or OCGN or EDIT a better buy right now?

For growth investors, Ocugen, Inc.

(OCGN) is the stronger pick with 8. 8% revenue growth year-over-year, versus -100. 0% for Editas Medicine, Inc. (EDIT). Analysts rate Ocugen, Inc. (OCGN) a "Buy" — based on 5 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — ADVM or OCGN or EDIT?

Over the past 5 years, Ocugen, Inc.

(OCGN) delivered a total return of -84. 3%, compared to -91. 1% for Editas Medicine, Inc. (EDIT). Over 10 years, the gap is even starker: ADVM returned -89. 2% versus OCGN's -98. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — ADVM or OCGN or EDIT?

By beta (market sensitivity over 5 years), Adverum Biotechnologies, Inc.

(ADVM) is the lower-risk stock at 1. 09β versus Editas Medicine, Inc. 's 2. 52β — meaning EDIT is approximately 131% more volatile than ADVM relative to the S&P 500. On balance sheet safety, Editas Medicine, Inc. (EDIT) carries a lower debt/equity ratio of 66% versus 130% for Adverum Biotechnologies, Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — ADVM or OCGN or EDIT?

By revenue growth (latest reported year), Ocugen, Inc.

(OCGN) is pulling ahead at 8. 8% versus -100. 0% for Editas Medicine, Inc. (EDIT). On earnings-per-share growth, the picture is similar: Editas Medicine, Inc. grew EPS 37. 5% year-over-year, compared to -227. 7% for Adverum Biotechnologies, Inc.. Over a 3-year CAGR, OCGN leads at 21. 0% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — ADVM or OCGN or EDIT?

Editas Medicine, Inc.

(EDIT) is the more profitable company, earning 0. 0% net margin versus -130. 9% for Adverum Biotechnologies, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: EDIT leads at 0. 0% versus -139. 2% for ADVM. At the gross margin level — before operating expenses — ADVM leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Which pays a better dividend — ADVM or OCGN or EDIT?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

07

Is ADVM or OCGN or EDIT better for a retirement portfolio?

For long-horizon retirement investors, Adverum Biotechnologies, Inc.

(ADVM) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 09)). Editas Medicine, Inc. (EDIT) carries a higher beta of 2. 52 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ADVM: -89. 2%, EDIT: -90. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

08

What are the main differences between ADVM and OCGN and EDIT?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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  • Market Cap > $100B
  • Gross Margin > 60%
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  • Gross Margin > 60%
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(ADVM: -100.0% · OCGN: -125.3%)

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