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ADVM logoAdverum Biotechnologies, Inc.(ADVM)Earnings, Financials & Key Ratios

ADVM•NASDAQ
$4.36
$96M mkt cap·Price updated Apr 24, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryCell and Gene Therapy Developers
AboutAdverum Biotechnologies, Inc., a clinical-stage gene therapy company, develops gene therapy product candidates to treat ocular and rare diseases. Its lead product candidate is ADVM-022, a single intravitreal injection gene therapy candidate used for the treatment of patients with chronic retinal, including wet age-related macular degeneration and diabetic macular edema. Adverum Biotechnologies, Inc. has license and collaboration agreements with University of California; Cornell University; GenSight; Lexeo; and Virovek. The company was formerly known as Avalanche Biotechnologies, Inc. and changed its name to Adverum Biotechnologies, Inc. in May 2016. Adverum Biotechnologies, Inc. was incorporated in 2006 and is headquartered in Redwood City, California.Show more
  • Revenue$1M-72.2%
  • EBITDA-$136M-9.9%
  • Net Income-$131M-7.2%
  • EPS (Diluted)-6.62-227.7%
  • Gross Margin100%
  • EBITDA Margin-13550.6%-295.6%
  • Operating Margin-13915.9%-288.5%
  • Net Margin-13092.7%-286.0%
  • ROE-189.84%-93.3%
  • ROIC-124.23%-83.8%
  • Debt/Equity1.30+17.7%
Technical→

ADVM Key Insights

Adverum Biotechnologies, Inc. (ADVM) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Momentum leader: RS Rating 80 (top 20%)
  • ✓Strong 5Y sales CAGR of 32.0%
  • ✓Share count reduced 65.9% through buybacks
  • ✓Trading at only 1.2x book value

✗Weaknesses

  • ✗Weak Piotroski F-Score: 3/9
  • ✗Negative free cash flow
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

ADVM Price & Volume

Adverum Biotechnologies, Inc. (ADVM) stock price & volume — 10-year historical chart

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ADVM Growth Metrics

Adverum Biotechnologies, Inc. (ADVM) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years5.75%
5 Years31.95%
3 Years-48.91%
TTM-100%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-88.39%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-109.27%

Return on Capital

10 Years-44.42%
5 Years-54.32%
3 Years-67.64%
Last Year-95.08%

ADVM Peer Comparison

Adverum Biotechnologies, Inc. (ADVM) competitors in Cell and Gene Therapy Developers — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
OCGN logoOCGNOcugen, Inc.Direct Competitor492.54M1.46-6.338.83%-15.37%-26.26%
EDIT logoEDITEditas Medicine, Inc.Direct Competitor310.73M3.18-1.76-100%-5.23%0.66
KRYS logoKRYSKrystal Biotech, Inc.Direct Competitor8.52B288.9042.2433.94%53.92%19.25%0.01
RARE logoRAREUltragenyx Pharmaceutical Inc.Product Competitor2.55B25.93-4.4520.13%-91.03%-6.08%
BMRN logoBMRNBioMarin Pharmaceutical Inc.Product Competitor10.5B54.6030.3312.87%8.29%4.41%0.11
SRPT logoSRPTSarepta Therapeutics, Inc.Product Competitor2.42B23.03-3.2315.58%2.98%4.89%0.91
FOLD logoFOLDAmicus Therapeutics, Inc.Product Competitor4.47B14.49-80.5032.29%-2.35%-6.1%2.29
RCKT logoRCKTRocket Pharmaceuticals, Inc.Product Competitor418.11M3.86-1.92-80.49%0.09

Compare ADVM vs Peers

Adverum Biotechnologies, Inc. (ADVM) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs OCGN

Most directly comparable listed peer for ADVM.

Scale Benchmark

vs REGN

Larger-name benchmark to compare ADVM against a more recognizable public peer.

Peer Set

Compare Top 5

vs OCGN, EDIT, KRYS, RARE

ADVM Income Statement

Adverum Biotechnologies, Inc. (ADVM) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
Line itemDec'16Dec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24TTM
Sales/Revenue1.46M1.85M1.61M250K07.5M03.6M1M0
Revenue Growth %-37.26%27.08%-12.82%-84.49%-100%--100%--72.22%-100%
Cost of Goods Sold00004.16M0000465K
COGS % of Revenue----------
Gross Profit
0▲ 0%
0▲ 0%
0▲ 0%
0▲ 0%
-4.16M▲ 0%
7.5M▲ 280.4%
0▼ 100.0%
3.6M▲ 0%
1M▼ 72.2%
-465K▲ 0%
Gross Margin %-----100%-100%100%-
Gross Profit Growth %-100%----280.38%-100%--72.22%-
Operating Expenses116.74M60.7M79.69M68.8M113.79M153.62M157.13M132.54M140.16M206.85M
OpEx % of Revenue8023.3%3282.64%4943.73%27518%-2048.29%-3681.72%14015.9%-
Selling, General & Admin24.36M20.86M24.56M28.38M44.64M64.44M57.86M55.06M63.12M79.44M
SG&A % of Revenue1673.88%1128.02%1523.57%11350.4%-859.21%-1529.33%6311.8%-
Research & Development31.67M39.84M50.13M40.42M73.31M89.18M99.28M77.49M77.04M128.88M
R&D % of Revenue2176.63%2154.62%3109.99%16167.6%-1189.08%-2152.39%7704.1%-
Other Operating Expenses60.71M05M0-4.16M0000-1000K
Operating Income
-115.28M▲ 0%
-58.85M▲ 49.0%
-78.08M▼ 32.7%
-68.55M▲ 12.2%
-117.95M▼ 72.1%
-146.12M▼ 23.9%
-157.13M▼ 7.5%
-128.94M▲ 17.9%
-139.16M▼ 7.9%
-207.32M▲ 0%
Operating Margin %-7923.3%-3182.64%-4843.73%-27418%--1948.29%--3581.72%-13915.9%-
Operating Income Growth %-141.06%48.95%-32.68%12.21%-72.08%-23.88%-7.54%17.94%-7.92%-
EBITDA-113.68M-56.75M-76.33M-66.97M-113.79M-141.48M-150.61M-123.3M-135.51M-204.82M
EBITDA Margin %-7813.13%-3069.28%-4735.17%-26788.8%--1886.36%--3424.94%-13550.6%-
EBITDA Growth %-141.82%50.08%-34.5%12.26%-69.91%-24.33%-6.45%18.13%-9.9%-80.25%
D&A (Non-Cash Add-back)1.6M2.1M1.75M1.57M4.16M4.64M6.53M5.64M3.65M2.49M
EBIT-54.57M-58.85M-73.08M-68.55M-116.39M-146.12M-157.13M-128.94M-139.16M-207.94M
Net Interest Income0000000000
Interest Income0000000000
Interest Expense0000000000
Other Income/Expense762K2.7M4.2M4.06M1.56M582K2.67M5.75M8.23M2.92M
Pretax Income
-114.52M▲ 0%
-56.15M▲ 51.0%
-73.88M▼ 31.6%
-64.49M▲ 12.7%
-116.39M▼ 80.5%
-145.54M▼ 25.0%
-154.46M▼ 6.1%
-123.19M▲ 20.2%
-130.93M▼ 6.3%
-204.39M▲ 0%
Pretax Margin %-7870.93%-3036.61%-4582.94%-25794.4%--1940.53%--3422.06%-13092.7%-
Income Tax-775K0-1.25M01.11M074K-1.08M00
Effective Tax Rate %0.68%0%1.69%0%-0.96%0%-0.05%0.88%0%0%
Net Income
-113.75M▲ 0%
-56.15M▲ 50.6%
-72.63M▼ 29.4%
-64.49M▲ 11.2%
-117.51M▼ 82.2%
-145.54M▼ 23.9%
-154.54M▼ 6.2%
-122.12M▲ 21.0%
-130.93M▼ 7.2%
-204.39M▲ 0%
Net Margin %-7817.66%-3036.61%-4505.4%-25794.4%--1940.53%--3392.11%-13092.7%-
Net Income Growth %-139.7%50.64%-29.35%11.21%-82.22%-23.86%-6.18%20.98%-7.22%-88.39%
Net Income (Continuing)-113.75M-56.15M-72.63M-64.49M-117.51M-145.54M-154.54M-122.12M-130.93M-204.39M
Discontinued Operations0000000000
Minority Interest0000000000
EPS (Diluted)
-3.14▲ 0%
-1.29▲ 58.9%
-1.18▲ 8.5%
-0.87▲ 26.3%
-1.26▼ 44.8%
-1.48▼ 17.5%
-2.67▼ 80.4%
-2.02▲ 24.3%
-6.62▼ 227.7%
-8.70▲ 0%
EPS Growth %-70.65%58.92%8.53%26.27%-44.83%-17.46%-80.41%24.34%-227.72%-109.27%
EPS (Basic)-3.14-1.29-1.18-0.87-1.26-1.48-2.67-2.02-6.62-
Diluted Shares Outstanding36.25M43.66M61.38M73.8M93.31M98.36M57.98M57.98M19.78M23.49M
Basic Shares Outstanding36.25M43.66M61.38M73.8M93.23M98.36M57.98M57.98M19.78M23.49M
Dividend Payout Ratio----------

ADVM Balance Sheet

Adverum Biotechnologies, Inc. (ADVM) balance sheet — assets, liabilities & shareholders' equity

Line itemDec'16Dec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24TTM
Total Current Assets225.27M193.74M208.75M175.87M434.44M317.14M190.59M102.77M131.3M28.91M
Cash & Short-Term Investments222.17M190.49M205.08M166.03M429.73M305.19M185.59M96.53M125.69M26.06M
Cash Only222.17M70.52M154.95M65.9M62.42M34.2M68.43M75M60.65M26.06M
Short-Term Investments0119.97M50.13M100.14M367.31M270.99M117.16M21.53M65.04M0
Accounts Receivable886K00005.71M0000
Days Sales Outstanding222.26----277.84----
Inventory0000000000
Days Inventory Outstanding----------
Other Current Assets03.26M3.67M9.84M06.25M5.01M6.25M5.61M2.85M
Total Non-Current Assets9.31M8.16M4.74M46.86M48.13M122.58M117.78M52.99M48.54M43.49M
Property, Plant & Equipment4.17M3.02M3.59M45.85M47.1M119.06M113.86M49.79M45.22M39.49M
Fixed Asset Turnover0.35x0.61x0.45x0.01x-0.06x-0.07x0.02x0.00x
Goodwill0000000000
Intangible Assets5M5M00000000
Long-Term Investments00999K999K03.27M2.5M001.98M
Other Non-Current Assets140K140K156K11K1.03M250K1.41M3.21M3.32M12.26M
Total Assets
234.58M▲ 0%
201.91M▼ 13.9%
213.5M▲ 5.7%
222.73M▲ 4.3%
482.57M▲ 116.7%
439.73M▼ 8.9%
308.37M▼ 29.9%
155.77M▼ 49.5%
179.84M▲ 15.5%
72.4M▲ 0%
Asset Turnover0.01x0.01x0.01x0.00x-0.02x-0.02x0.01x0.00x
Asset Growth %-11.25%-13.93%5.74%4.32%116.66%-8.88%-29.87%-49.49%15.45%-164.36%
Total Current Liabilities9.9M10.67M10.72M19.41M20.87M21.32M32.25M19.98M22.9M44.75M
Accounts Payable1.47M1.73M1.71M4.1M2.81M1.39M2.24M1.92M1.61M12.46M
Days Payables Outstanding----246.67----4.05K
Short-Term Debt0004.13M01.89M0005.81M
Deferred Revenue (Current)1.85M1.85M-100K0000000
Other Current Liabilities4M4.83M6.07M7.12M9.63M7.52M9.13M8.77M5.96M16.66M
Current Ratio22.76x18.15x19.48x9.06x20.82x14.88x5.91x5.14x5.73x5.73x
Quick Ratio22.76x18.15x19.48x9.06x20.82x14.88x5.91x5.14x5.73x5.73x
Cash Conversion Cycle----------
Total Non-Current Liabilities9.09M7.2M1.61M28.36M27.35M102.22M94.61M68.56M86.23M83.31M
Long-Term Debt000100K000000
Capital Lease Obligations00028.21M26.23M101.11M93.56M68.56M86.04M339.97M
Deferred Tax Liabilities1.25M1.25M00000000
Other Non-Current Liabilities738K703K1.41M48K1.11M1.11M1.05M0192K744K
Total Liabilities18.98M17.88M12.33M47.77M48.22M123.54M126.85M88.55M109.13M128.05M
Total Debt0400K300K32.45M30.71M102.99M106.8M74.04M91.7M88.94M
Net Debt-222.17M-70.12M-154.65M-33.45M-31.72M68.8M38.37M-959K31.05M62.88M
Debt / Equity-0.00x0.00x0.19x0.07x0.33x0.59x1.10x1.30x1.30x
Debt / EBITDA----------0.43x
Net Debt / EBITDA----------0.31x
Interest Coverage----------
Total Equity
215.6M▲ 0%
184.03M▼ 14.6%
201.17M▲ 9.3%
174.96M▼ 13.0%
434.35M▲ 148.3%
316.19M▼ 27.2%
181.52M▼ 42.6%
67.22M▼ 63.0%
70.71M▲ 5.2%
-55.65M▲ 0%
Equity Growth %-14.64%-14.64%9.31%-13.03%148.26%-27.2%-42.59%-62.97%5.19%-330.96%
Book Value per Share5.954.213.282.374.653.213.131.163.57-2.37
Total Shareholders' Equity215.6M184.03M201.17M174.96M434.35M316.19M181.52M67.22M70.71M-55.65M
Common Stock4K5K6K7K10K10K10K1K2K2K
Retained Earnings-197.91M-254.06M-320.54M-385.03M-502.54M-648.08M-802.61M-936.02M-1.07B-1.21B
Treasury Stock0000000000
Accumulated OCI-7K-963K-799K-725K-261K-714K-1.53M-473K-407K-440K
Minority Interest0000000000

ADVM Cash Flow Statement

Adverum Biotechnologies, Inc. (ADVM) cash flow — operating, investing & free cash flow history

Line itemDec'16Dec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24TTM
Cash from Operations-38.37M-45.42M-53.96M-49.17M-79.29M-107.83M-108.09M-90.9M-92.46M-92.46M
Operating CF Margin %-2636.84%-2456.52%-3347.64%-19668%--1437.75%--2525.06%-9246.2%-
Operating CF Growth %-8.57%-18.39%-18.81%8.88%-61.26%-35.99%-0.24%15.9%-1.72%-244.43%
Net Income-113.75M-56.15M-72.63M-64.49M-117.51M-145.54M-154.54M-122.12M-130.93M-204.39M
Depreciation & Amortization1.6M2.1M1.75M1.57M4.16M4.64M6.53M5.64M3.65M2.49M
Stock-Based Compensation11.42M8.72M13.43M9.9M20.39M25.19M20.08M17.57M14.35M7.55M
Deferred Taxes60.71M593K-1.25M-1.27M863K3.83M0000
Other Non-Cash Items8K70K6.35M58K75K-25K-51K16.51M19.55M3.56M
Working Capital Changes1.64M-756K-1.62M5.06M12.73M4.06M19.89M-8.51M911K33.28M
Change in Receivables-437K886K00000000
Change in Inventory-1.11M-29K00000000
Change in Payables-111K333K-67K-650K1.58M-1.61M845K-369K-262K10.39M
Cash from Investing38.77M-122.2M69.44M-68.07M-280.17M78.71M141.72M96.88M-41.89M60.85M
Capital Expenditures-2.41M-1.02M-809K-19.25M-11.84M-15.12M-11.82M-808K-388K-543K
CapEx % of Revenue165.77%54.95%50.19%7698.8%-201.64%-22.44%38.8%-
Acquisitions3.45M000000000
Investments----------
Other Investing38.77M000000000
Cash from Financing556K16.75M69.95M28.19M355.99M2.4M607K69K120M10.26M
Debt Issued (Net)00-175K-112K-61K-240K0000
Equity Issued (Net)01000K1000K1000K1000K1000K607K489K1000K1.36M
Dividends Paid0000000000
Share Repurchases0000000000
Other Financing556K229K-63K2.41M11.74M952K0-420K642K0
Net Change in Cash
822K▲ 0%
-151.65M▼ 18549.0%
85.43M▲ 156.3%
-89.05M▼ 204.2%
-3.47M▲ 96.1%
-26.73M▼ 669.5%
34.24M▲ 228.1%
6.04M▼ 82.4%
-14.35M▼ 337.5%
-66.79M▲ 0%
Free Cash Flow
-40.78M▲ 0%
-46.44M▼ 13.9%
-54.77M▼ 18.0%
-68.42M▼ 24.9%
-91.14M▼ 33.2%
-122.95M▼ 34.9%
-119.91M▲ 2.5%
-91.71M▲ 23.5%
-92.85M▼ 1.2%
-138.44M▲ 0%
FCF Margin %-2802.61%-2511.47%-3397.83%-27366.8%--1639.39%--2547.5%-9285%-
FCF Growth %-6.39%-13.88%-17.95%-24.91%-33.21%-34.91%2.48%23.52%-1.24%-60.73%
FCF per Share-1.13-1.06-0.89-0.93-0.98-1.25-2.07-1.58-4.69-4.69
FCF Conversion (FCF/Net Income)0.34x0.81x0.74x0.76x0.67x0.74x0.70x0.74x0.71x0.68x
Interest Paid0000000000
Taxes Paid0000000000

ADVM Key Ratios

Adverum Biotechnologies, Inc. (ADVM) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric201620172018201920202021202220232024TTM
Return on Equity (ROE)-48.59%-28.1%-37.71%-34.29%-38.57%-38.78%-62.1%-98.19%-189.84%-3844.85%
Return on Invested Capital (ROIC)--82.24%-73.01%-54.68%-32.51%-27.83%-38.97%-67.59%-124.23%-124.23%
Gross Margin-----100%-100%100%-
Net Margin-7817.66%-3036.61%-4505.4%-25794.4%--1940.53%--3392.11%-13092.7%-
Debt / Equity-0.00x0.00x0.19x0.07x0.33x0.59x1.10x1.30x1.30x
FCF Conversion0.34x0.81x0.74x0.76x0.67x0.74x0.70x0.74x0.71x0.68x
Revenue Growth-37.26%27.08%-12.82%-84.49%-100%--100%--72.22%-100%

ADVM Frequently Asked Questions

Adverum Biotechnologies, Inc. (ADVM) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Adverum Biotechnologies, Inc. (ADVM) reported $1.0M in revenue for fiscal year 2024. This represents a 3233% increase from $0.0M in 2012.

Adverum Biotechnologies, Inc. (ADVM) saw revenue decline by 72.2% over the past year.

Adverum Biotechnologies, Inc. (ADVM) reported a net loss of $204.4M for fiscal year 2024.

Dividend & Returns

Adverum Biotechnologies, Inc. (ADVM) has a return on equity (ROE) of -189.8%. Negative ROE indicates the company is unprofitable.

Adverum Biotechnologies, Inc. (ADVM) had negative free cash flow of $138.4M in fiscal year 2024, likely due to heavy capital investments.

Explore More ADVM

Adverum Biotechnologies, Inc. (ADVM) financial analysis — history, returns, DCA and operating performance tools

Total Return Calculator

Historical returns with dividends reinvested

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Dividend History

Yield, growth, payout safety & DRIP

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Earnings History

EPS trends, net income & profitability

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Price History

Long-term charts & historical price data

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Revenue History

Sales growth patterns & revenue breakdown

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Financial Ratios

30 years of market, efficiency and balance-sheet ratios

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Valuation

DCF intrinsic value, peer multiples & estimates

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