Biotechnology
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GRCE vs FOLD
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
GRCE vs FOLD — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||
|---|---|---|
| Industry | Biotechnology | Biotechnology |
| Market Cap | $37M | $4.47B |
| Revenue (TTM) | $0.00 | $599M |
| Net Income (TTM) | $-6M | $-14M |
| Gross Margin | — | 89.5% |
| Operating Margin | — | 5.5% |
| Forward P/E | — | 40.6x |
| Total Debt | $0.00 | $444M |
| Cash & Equiv. | $22M | $214M |
GRCE vs FOLD — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Oct 24 | May 26 | Return |
|---|---|---|---|
| Grace Therapeutics,… (GRCE) | 100 | 74.1 | -25.9% |
| Amicus Therapeutics… (FOLD) | 100 | 126.6 | +26.6% |
Price return only. Dividends and distributions are not included.
Quick Verdict: GRCE vs FOLD
Each card shows where this stock fits in a portfolio — not just who wins on paper.
GRCE is the clearest fit if your priority is growth and quality.
- 55.3% revenue growth vs FOLD's 32.3%
- 1.0% margin vs FOLD's -2.3%
FOLD carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- beta 0.63
- Rev growth 32.3%, EPS growth 64.7%, 3Y rev CAGR 20.0%
- 125.0% 10Y total return vs GRCE's -21.3%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 55.3% revenue growth vs FOLD's 32.3% | |
| Quality / Margins | 1.0% margin vs FOLD's -2.3% | |
| Stability / Safety | Beta 0.63 vs GRCE's 0.87 | |
| Dividends | Tie | Neither stock pays a meaningful dividend |
| Momentum (1Y) | +134.1% vs GRCE's -19.7% | |
| Efficiency (ROA) | -1.6% ROA vs GRCE's -8.7%, ROIC 4.8% vs -30.1% |
GRCE vs FOLD — Financial Metrics
Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.
Income & Cash Flow (Last 12 Months)
FOLD leads this category, winning 1 of 1 comparable metric.
Income & Cash Flow (Last 12 Months)
FOLD and GRCE operate at a comparable scale, with $599M and $0 in trailing revenue.
| Metric | ||
|---|---|---|
| RevenueTrailing 12 months | $0 | $599M |
| EBITDAEarnings before interest/tax | -$9M | $40M |
| Net IncomeAfter-tax profit | -$6M | -$14M |
| Free Cash FlowCash after capex | -$10M | $10M |
| Gross MarginGross profit ÷ Revenue | — | +89.5% |
| Operating MarginEBIT ÷ Revenue | — | +5.5% |
| Net MarginNet income ÷ Revenue | — | -2.3% |
| FCF MarginFCF ÷ Revenue | — | +1.6% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | +19.5% |
| EPS Growth (YoY)Latest quarter vs prior year | +61.1% | +3.8% |
Valuation Metrics
Evenly matched — GRCE and FOLD each lead in 1 of 2 comparable metrics.
Valuation Metrics
| Metric | ||
|---|---|---|
| Market CapShares × price | $37M | $4.5B |
| Enterprise ValueMkt cap + debt − cash | $15M | $4.7B |
| Trailing P/EPrice ÷ TTM EPS | -3.00x | -80.50x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 40.62x |
| PEG RatioP/E ÷ EPS growth rate | — | — |
| EV / EBITDAEnterprise value multiple | — | 140.62x |
| Price / SalesMarket cap ÷ Revenue | — | 8.46x |
| Price / BookPrice ÷ Book value/share | 0.43x | 22.73x |
| Price / FCFMarket cap ÷ FCF | — | — |
Profitability & Efficiency
FOLD leads this category, winning 5 of 7 comparable metrics.
Profitability & Efficiency
FOLD delivers a -6.1% return on equity — every $100 of shareholder capital generates $-6 in annual profit, vs $-9 for GRCE. On the Piotroski fundamental quality scale (0–9), FOLD scores 5/9 vs GRCE's 1/9, reflecting solid financial health.
| Metric | ||
|---|---|---|
| ROE (TTM)Return on equity | -9.2% | -6.1% |
| ROA (TTM)Return on assets | -8.7% | -1.6% |
| ROICReturn on invested capital | -30.1% | +4.8% |
| ROCEReturn on capital employed | -23.5% | +4.0% |
| Piotroski ScoreFundamental quality 0–9 | 1 | 5 |
| Debt / EquityFinancial leverage | — | 2.29x |
| Net DebtTotal debt minus cash | -$22M | $230M |
| Cash & Equiv.Liquid assets | $22M | $214M |
| Total DebtShort + long-term debt | $0 | $444M |
| Interest CoverageEBIT ÷ Interest expense | — | 1.11x |
Total Returns (Dividends Reinvested)
FOLD leads this category, winning 6 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in FOLD five years ago would be worth $15,094 today (with dividends reinvested), compared to $7,874 for GRCE. Over the past 12 months, FOLD leads with a +134.1% total return vs GRCE's -19.7%. The 3-year compound annual growth rate (CAGR) favors FOLD at 6.0% vs GRCE's -7.7% — a key indicator of consistent wealth creation.
| Metric | ||
|---|---|---|
| YTD ReturnYear-to-date | -35.2% | +1.5% |
| 1-Year ReturnPast 12 months | -19.7% | +134.1% |
| 3-Year ReturnCumulative with dividends | -21.3% | +19.0% |
| 5-Year ReturnCumulative with dividends | -21.3% | +50.9% |
| 10-Year ReturnCumulative with dividends | -21.3% | +125.0% |
| CAGR (3Y)Annualised 3-year return | -7.7% | +6.0% |
Risk & Volatility
FOLD leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
FOLD is the less volatile stock with a 0.63 beta — it tends to amplify market swings less than GRCE's 0.87 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. FOLD currently trades 99.9% from its 52-week high vs GRCE's 45.8% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.87x | 0.63x |
| 52-Week HighHighest price in past year | $5.18 | $14.50 |
| 52-Week LowLowest price in past year | $1.79 | $5.51 |
| % of 52W HighCurrent price vs 52-week peak | +45.8% | +99.9% |
| RSI (14)Momentum oscillator 0–100 | 32.2 | 72.2 |
| Avg Volume (50D)Average daily shares traded | 881K | 3.0M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
| Metric | ||
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy |
| Price TargetConsensus 12-month target | — | $14.50 |
| # AnalystsCovering analysts | — | 24 |
| Dividend YieldAnnual dividend ÷ price | — | — |
| Dividend StreakConsecutive years of raises | — | — |
| Dividend / ShareAnnual DPS | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% |
FOLD leads in 4 of 6 categories — strongest in Income & Cash Flow and Profitability & Efficiency. 1 category is tied.
GRCE vs FOLD: Frequently Asked Questions
8 questions · data-driven answers · updated daily
01Is GRCE or FOLD a better buy right now?
Analysts rate Amicus Therapeutics, Inc.
(FOLD) a "Buy" — based on 24 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — GRCE or FOLD?
Over the past 5 years, Amicus Therapeutics, Inc.
(FOLD) delivered a total return of +50. 9%, compared to -21. 3% for Grace Therapeutics, Inc. (GRCE). Over 10 years, the gap is even starker: FOLD returned +125. 0% versus GRCE's -21. 3%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — GRCE or FOLD?
By beta (market sensitivity over 5 years), Amicus Therapeutics, Inc.
(FOLD) is the lower-risk stock at 0. 63β versus Grace Therapeutics, Inc. 's 0. 87β — meaning GRCE is approximately 37% more volatile than FOLD relative to the S&P 500.
04Which is growing faster — GRCE or FOLD?
On earnings-per-share growth, the picture is similar: Amicus Therapeutics, Inc.
grew EPS 64. 7% year-over-year, compared to 54. 3% for Grace Therapeutics, Inc.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — GRCE or FOLD?
Grace Therapeutics, Inc.
(GRCE) is the more profitable company, earning 0. 0% net margin versus -10. 6% for Amicus Therapeutics, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: FOLD leads at 4. 7% versus 0. 0% for GRCE. At the gross margin level — before operating expenses — FOLD leads at 90. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — GRCE or FOLD?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is GRCE or FOLD better for a retirement portfolio?
For long-horizon retirement investors, Amicus Therapeutics, Inc.
(FOLD) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 63), +125. 0% 10Y return). Both have compounded well over 10 years (FOLD: +125. 0%, GRCE: -21. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between GRCE and FOLD?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: GRCE is a small-cap quality compounder stock; FOLD is a small-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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