Biotechnology
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YDES vs ZLAB
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
YDES vs ZLAB — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||
|---|---|---|
| Industry | Biotechnology | Biotechnology |
| Market Cap | $22M | $2.19B |
| Revenue (TTM) | $0.00 | $460M |
| Net Income (TTM) | $-3M | $-176M |
| Gross Margin | 30.4% | 58.5% |
| Operating Margin | -286.5% | -49.9% |
| Total Debt | $23K | $224M |
| Cash & Equiv. | $3M | $680M |
Quick Verdict: YDES vs ZLAB
Each card shows where this stock fits in a portfolio — not just who wins on paper.
YDES is the clearest fit if your priority is income & stability and growth exposure.
- beta 0.81
- Rev growth 45.8%
- Lower volatility, beta 0.81, Low D/E 0.3%, current ratio 13.18x
ZLAB carries the broadest edge in this set and is the clearest fit for long-term compounding.
- -29.2% 10Y total return vs YDES's -56.1%
- -38.1% margin vs YDES's -276.6%
- -30.3% vs YDES's -56.1%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 45.8% revenue growth vs ZLAB's 15.3% | |
| Quality / Margins | -38.1% margin vs YDES's -276.6% | |
| Stability / Safety | Beta 0.81 vs ZLAB's 1.21, lower leverage | |
| Dividends | Tie | Neither stock pays a meaningful dividend |
| Momentum (1Y) | -30.3% vs YDES's -56.1% | |
| Efficiency (ROA) | -15.0% ROA vs YDES's -100.8%, ROIC -42.8% vs -63.3% |
YDES vs ZLAB — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
YDES vs ZLAB — Financial Metrics
Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.
Income & Cash Flow (Last 12 Months)
ZLAB leads this category, winning 5 of 5 comparable metrics.
Income & Cash Flow (Last 12 Months)
ZLAB and YDES operate at a comparable scale, with $460M and $0 in trailing revenue. Profitability is closely matched — net margins range from -38.1% (ZLAB) to -2.8% (YDES).
| Metric | ||
|---|---|---|
| RevenueTrailing 12 months | $0 | $460M |
| EBITDAEarnings before interest/tax | -$3M | -$214M |
| Net IncomeAfter-tax profit | -$3M | -$176M |
| Free Cash FlowCash after capex | -$1M | -$159M |
| Gross MarginGross profit ÷ Revenue | +30.4% | +58.5% |
| Operating MarginEBIT ÷ Revenue | -2.9% | -49.9% |
| Net MarginNet income ÷ Revenue | -2.8% | -38.1% |
| FCF MarginFCF ÷ Revenue | -9.3% | -34.5% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | +17.0% |
| EPS Growth (YoY)Latest quarter vs prior year | -116.0% | +42.5% |
Valuation Metrics
ZLAB leads this category, winning 3 of 3 comparable metrics.
Valuation Metrics
| Metric | ||
|---|---|---|
| Market CapShares × price | $22M | $2.2B |
| Enterprise ValueMkt cap + debt − cash | $19M | $1.7B |
| Trailing P/EPrice ÷ TTM EPS | -9.45x | -12.35x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — |
| EV / EBITDAEnterprise value multiple | — | — |
| Price / SalesMarket cap ÷ Revenue | 42.99x | 4.75x |
| Price / BookPrice ÷ Book value/share | 3.33x | 3.03x |
| Price / FCFMarket cap ÷ FCF | — | — |
Profitability & Efficiency
ZLAB leads this category, winning 6 of 8 comparable metrics.
Profitability & Efficiency
ZLAB delivers a -22.8% return on equity — every $100 of shareholder capital generates $-23 in annual profit, vs $-43 for YDES. YDES carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to ZLAB's 0.31x.
| Metric | ||
|---|---|---|
| ROE (TTM)Return on equity | -42.7% | -22.8% |
| ROA (TTM)Return on assets | -100.8% | -15.0% |
| ROICReturn on invested capital | -63.3% | -42.8% |
| ROCEReturn on capital employed | -44.1% | -27.9% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 3 |
| Debt / EquityFinancial leverage | 0.00x | 0.31x |
| Net DebtTotal debt minus cash | -$3M | -$455M |
| Cash & Equiv.Liquid assets | $3M | $680M |
| Total DebtShort + long-term debt | $22,555 | $224M |
| Interest CoverageEBIT ÷ Interest expense | -1893.69x | -33.25x |
Total Returns (Dividends Reinvested)
ZLAB leads this category, winning 5 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in YDES five years ago would be worth $4,395 today (with dividends reinvested), compared to $1,250 for ZLAB. Over the past 12 months, ZLAB leads with a -30.3% total return vs YDES's -56.1%. The 3-year compound annual growth rate (CAGR) favors ZLAB at -18.9% vs YDES's -24.0% — a key indicator of consistent wealth creation.
| Metric | ||
|---|---|---|
| YTD ReturnYear-to-date | -55.9% | +14.1% |
| 1-Year ReturnPast 12 months | -56.1% | -30.3% |
| 3-Year ReturnCumulative with dividends | -56.1% | -46.6% |
| 5-Year ReturnCumulative with dividends | -56.1% | -87.5% |
| 10-Year ReturnCumulative with dividends | -56.1% | -29.2% |
| CAGR (3Y)Annualised 3-year return | -24.0% | -18.9% |
Risk & Volatility
Evenly matched — YDES and ZLAB each lead in 1 of 2 comparable metrics.
Risk & Volatility
YDES is the less volatile stock with a 0.81 beta — it tends to amplify market swings less than ZLAB's 1.21 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ZLAB currently trades 44.6% from its 52-week high vs YDES's 21.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.81x | 1.21x |
| 52-Week HighHighest price in past year | $25.00 | $44.34 |
| 52-Week LowLowest price in past year | $4.73 | $15.96 |
| % of 52W HighCurrent price vs 52-week peak | +21.2% | +44.6% |
| RSI (14)Momentum oscillator 0–100 | 39.6 | 47.7 |
| Avg Volume (50D)Average daily shares traded | 20K | 729K |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
| Metric | ||
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy |
| Price TargetConsensus 12-month target | — | $35.00 |
| # AnalystsCovering analysts | — | 11 |
| Dividend YieldAnnual dividend ÷ price | — | — |
| Dividend StreakConsecutive years of raises | — | — |
| Dividend / ShareAnnual DPS | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% |
ZLAB leads in 4 of 6 categories — strongest in Income & Cash Flow and Valuation Metrics. 1 category is tied.
YDES vs ZLAB: Frequently Asked Questions
8 questions · data-driven answers · updated daily
01Is YDES or ZLAB a better buy right now?
For growth investors, YD Bio Limited Ordinary Shares (YDES) is the stronger pick with 45.
8% revenue growth year-over-year, versus 15. 3% for Zai Lab Limited (ZLAB). Analysts rate Zai Lab Limited (ZLAB) a "Buy" — based on 11 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — YDES or ZLAB?
Over the past 5 years, YD Bio Limited Ordinary Shares (YDES) delivered a total return of -56.
1%, compared to -87. 5% for Zai Lab Limited (ZLAB). Over 10 years, the gap is even starker: ZLAB returned -29. 2% versus YDES's -56. 1%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — YDES or ZLAB?
By beta (market sensitivity over 5 years), YD Bio Limited Ordinary Shares (YDES) is the lower-risk stock at 0.
81β versus Zai Lab Limited's 1. 21β — meaning ZLAB is approximately 49% more volatile than YDES relative to the S&P 500. On balance sheet safety, YD Bio Limited Ordinary Shares (YDES) carries a lower debt/equity ratio of 0% versus 31% for Zai Lab Limited — giving it more financial flexibility in a downturn.
04Which is growing faster — YDES or ZLAB?
By revenue growth (latest reported year), YD Bio Limited Ordinary Shares (YDES) is pulling ahead at 45.
8% versus 15. 3% for Zai Lab Limited (ZLAB). Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — YDES or ZLAB?
Zai Lab Limited (ZLAB) is the more profitable company, earning -38.
1% net margin versus -276. 6% for YD Bio Limited Ordinary Shares — meaning it keeps -38. 1% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ZLAB leads at -49. 9% versus -286. 5% for YDES. At the gross margin level — before operating expenses — ZLAB leads at 58. 6%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — YDES or ZLAB?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is YDES or ZLAB better for a retirement portfolio?
For long-horizon retirement investors, YD Bio Limited Ordinary Shares (YDES) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.
81)). Both have compounded well over 10 years (YDES: -56. 1%, ZLAB: -29. 2%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between YDES and ZLAB?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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