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Stock Comparison

YDES vs ZLAB

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
YDES
YD Bio Limited Ordinary Shares

Biotechnology

HealthcareNASDAQ • TW
Market Cap$22M
5Y Perf.-15.2%
ZLAB
Zai Lab Limited

Biotechnology

HealthcareNASDAQ • CN
Market Cap$2.19B
5Y Perf.-34.0%

YDES vs ZLAB — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
YDES logoYDES
ZLAB logoZLAB
IndustryBiotechnologyBiotechnology
Market Cap$22M$2.19B
Revenue (TTM)$0.00$460M
Net Income (TTM)$-3M$-176M
Gross Margin30.4%58.5%
Operating Margin-286.5%-49.9%
Total Debt$23K$224M
Cash & Equiv.$3M$680M

Quick Verdict: YDES vs ZLAB

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: ZLAB leads in 3 of 6 categories, making it the strongest pick for profitability and margin quality and recent price momentum and sentiment. YD Bio Limited Ordinary Shares is the stronger pick specifically for growth and revenue expansion and capital preservation and lower volatility. As sector peers, any of these can serve as alternatives in the same allocation.
YDES
YD Bio Limited Ordinary Shares
The Income Pick

YDES is the clearest fit if your priority is income & stability and growth exposure.

  • beta 0.81
  • Rev growth 45.8%
  • Lower volatility, beta 0.81, Low D/E 0.3%, current ratio 13.18x
Best for: income & stability and growth exposure
ZLAB
Zai Lab Limited
The Long-Run Compounder

ZLAB carries the broadest edge in this set and is the clearest fit for long-term compounding.

  • -29.2% 10Y total return vs YDES's -56.1%
  • -38.1% margin vs YDES's -276.6%
  • -30.3% vs YDES's -56.1%
Best for: long-term compounding
See the full category breakdown
CategoryWinnerWhy
GrowthYDES logoYDES45.8% revenue growth vs ZLAB's 15.3%
Quality / MarginsZLAB logoZLAB-38.1% margin vs YDES's -276.6%
Stability / SafetyYDES logoYDESBeta 0.81 vs ZLAB's 1.21, lower leverage
DividendsTieNeither stock pays a meaningful dividend
Momentum (1Y)ZLAB logoZLAB-30.3% vs YDES's -56.1%
Efficiency (ROA)ZLAB logoZLAB-15.0% ROA vs YDES's -100.8%, ROIC -42.8% vs -63.3%

YDES vs ZLAB — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

YDESYD Bio Limited Ordinary Shares

Segment breakdown not available.

ZLABZai Lab Limited
FY 2025
Zejula
56.5%$189M
Nuzyra
18.2%$61M
Optune
14.4%$48M
Qinlock
10.6%$36M
Product and Service, Other
0.2%$717,000

YDES vs ZLAB — Financial Metrics

Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLZLABLAGGINGYDES

Income & Cash Flow (Last 12 Months)

ZLAB leads this category, winning 5 of 5 comparable metrics.

ZLAB and YDES operate at a comparable scale, with $460M and $0 in trailing revenue. Profitability is closely matched — net margins range from -38.1% (ZLAB) to -2.8% (YDES).

MetricYDES logoYDESYD Bio Limited Or…ZLAB logoZLABZai Lab Limited
RevenueTrailing 12 months$0$460M
EBITDAEarnings before interest/tax-$3M-$214M
Net IncomeAfter-tax profit-$3M-$176M
Free Cash FlowCash after capex-$1M-$159M
Gross MarginGross profit ÷ Revenue+30.4%+58.5%
Operating MarginEBIT ÷ Revenue-2.9%-49.9%
Net MarginNet income ÷ Revenue-2.8%-38.1%
FCF MarginFCF ÷ Revenue-9.3%-34.5%
Rev. Growth (YoY)Latest quarter vs prior year+17.0%
EPS Growth (YoY)Latest quarter vs prior year-116.0%+42.5%
ZLAB leads this category, winning 5 of 5 comparable metrics.

Valuation Metrics

ZLAB leads this category, winning 3 of 3 comparable metrics.
MetricYDES logoYDESYD Bio Limited Or…ZLAB logoZLABZai Lab Limited
Market CapShares × price$22M$2.2B
Enterprise ValueMkt cap + debt − cash$19M$1.7B
Trailing P/EPrice ÷ TTM EPS-9.45x-12.35x
Forward P/EPrice ÷ next-FY EPS est.
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple
Price / SalesMarket cap ÷ Revenue42.99x4.75x
Price / BookPrice ÷ Book value/share3.33x3.03x
Price / FCFMarket cap ÷ FCF
ZLAB leads this category, winning 3 of 3 comparable metrics.

Profitability & Efficiency

ZLAB leads this category, winning 6 of 8 comparable metrics.

ZLAB delivers a -22.8% return on equity — every $100 of shareholder capital generates $-23 in annual profit, vs $-43 for YDES. YDES carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to ZLAB's 0.31x.

MetricYDES logoYDESYD Bio Limited Or…ZLAB logoZLABZai Lab Limited
ROE (TTM)Return on equity-42.7%-22.8%
ROA (TTM)Return on assets-100.8%-15.0%
ROICReturn on invested capital-63.3%-42.8%
ROCEReturn on capital employed-44.1%-27.9%
Piotroski ScoreFundamental quality 0–933
Debt / EquityFinancial leverage0.00x0.31x
Net DebtTotal debt minus cash-$3M-$455M
Cash & Equiv.Liquid assets$3M$680M
Total DebtShort + long-term debt$22,555$224M
Interest CoverageEBIT ÷ Interest expense-1893.69x-33.25x
ZLAB leads this category, winning 6 of 8 comparable metrics.

Total Returns (Dividends Reinvested)

ZLAB leads this category, winning 5 of 6 comparable metrics.

A $10,000 investment in YDES five years ago would be worth $4,395 today (with dividends reinvested), compared to $1,250 for ZLAB. Over the past 12 months, ZLAB leads with a -30.3% total return vs YDES's -56.1%. The 3-year compound annual growth rate (CAGR) favors ZLAB at -18.9% vs YDES's -24.0% — a key indicator of consistent wealth creation.

MetricYDES logoYDESYD Bio Limited Or…ZLAB logoZLABZai Lab Limited
YTD ReturnYear-to-date-55.9%+14.1%
1-Year ReturnPast 12 months-56.1%-30.3%
3-Year ReturnCumulative with dividends-56.1%-46.6%
5-Year ReturnCumulative with dividends-56.1%-87.5%
10-Year ReturnCumulative with dividends-56.1%-29.2%
CAGR (3Y)Annualised 3-year return-24.0%-18.9%
ZLAB leads this category, winning 5 of 6 comparable metrics.

Risk & Volatility

Evenly matched — YDES and ZLAB each lead in 1 of 2 comparable metrics.

YDES is the less volatile stock with a 0.81 beta — it tends to amplify market swings less than ZLAB's 1.21 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ZLAB currently trades 44.6% from its 52-week high vs YDES's 21.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricYDES logoYDESYD Bio Limited Or…ZLAB logoZLABZai Lab Limited
Beta (5Y)Sensitivity to S&P 5000.81x1.21x
52-Week HighHighest price in past year$25.00$44.34
52-Week LowLowest price in past year$4.73$15.96
% of 52W HighCurrent price vs 52-week peak+21.2%+44.6%
RSI (14)Momentum oscillator 0–10039.647.7
Avg Volume (50D)Average daily shares traded20K729K
Evenly matched — YDES and ZLAB each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.
MetricYDES logoYDESYD Bio Limited Or…ZLAB logoZLABZai Lab Limited
Analyst RatingConsensus buy/hold/sellBuy
Price TargetConsensus 12-month target$35.00
# AnalystsCovering analysts11
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

ZLAB leads in 4 of 6 categories — strongest in Income & Cash Flow and Valuation Metrics. 1 category is tied.

Best OverallZai Lab Limited (ZLAB)Leads 4 of 6 categories
Loading custom metrics...

YDES vs ZLAB: Frequently Asked Questions

8 questions · data-driven answers · updated daily

01

Is YDES or ZLAB a better buy right now?

For growth investors, YD Bio Limited Ordinary Shares (YDES) is the stronger pick with 45.

8% revenue growth year-over-year, versus 15. 3% for Zai Lab Limited (ZLAB). Analysts rate Zai Lab Limited (ZLAB) a "Buy" — based on 11 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — YDES or ZLAB?

Over the past 5 years, YD Bio Limited Ordinary Shares (YDES) delivered a total return of -56.

1%, compared to -87. 5% for Zai Lab Limited (ZLAB). Over 10 years, the gap is even starker: ZLAB returned -29. 2% versus YDES's -56. 1%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — YDES or ZLAB?

By beta (market sensitivity over 5 years), YD Bio Limited Ordinary Shares (YDES) is the lower-risk stock at 0.

81β versus Zai Lab Limited's 1. 21β — meaning ZLAB is approximately 49% more volatile than YDES relative to the S&P 500. On balance sheet safety, YD Bio Limited Ordinary Shares (YDES) carries a lower debt/equity ratio of 0% versus 31% for Zai Lab Limited — giving it more financial flexibility in a downturn.

04

Which is growing faster — YDES or ZLAB?

By revenue growth (latest reported year), YD Bio Limited Ordinary Shares (YDES) is pulling ahead at 45.

8% versus 15. 3% for Zai Lab Limited (ZLAB). Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — YDES or ZLAB?

Zai Lab Limited (ZLAB) is the more profitable company, earning -38.

1% net margin versus -276. 6% for YD Bio Limited Ordinary Shares — meaning it keeps -38. 1% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ZLAB leads at -49. 9% versus -286. 5% for YDES. At the gross margin level — before operating expenses — ZLAB leads at 58. 6%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Which pays a better dividend — YDES or ZLAB?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

07

Is YDES or ZLAB better for a retirement portfolio?

For long-horizon retirement investors, YD Bio Limited Ordinary Shares (YDES) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

81)). Both have compounded well over 10 years (YDES: -56. 1%, ZLAB: -29. 2%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

08

What are the main differences between YDES and ZLAB?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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YDES

High-Growth Disruptor

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 22%
  • Gross Margin > 18%
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High-Growth Disruptor

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 8%
  • Gross Margin > 35%
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