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ACLX vs DBVT vs SANA vs IMVT
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
ACLX vs DBVT vs SANA vs IMVT — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $6.73B | $1712.35T | $918M | $5.53B |
| Revenue (TTM) | $22M | $0.00 | $0.00 | $0.00 |
| Net Income (TTM) | $-229M | $-168M | $-234M | $-464M |
| Gross Margin | -64.8% | — | — | — |
| Operating Margin | -11.4% | — | — | — |
| Total Debt | $96M | $22M | $94M | $98K |
| Cash & Equiv. | $80M | $194M | $128M | $714M |
ACLX vs DBVT vs SANA vs IMVT — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Feb 22 | Apr 26 | Return |
|---|---|---|---|
| Arcellx, Inc. (ACLX) | 100 | 601.2 | +501.2% |
| DBV Technologies S.… (DBVT) | 100 | 155.9 | +55.9% |
| Sana Biotechnology,… (SANA) | 100 | 44.6 | -55.4% |
| Immunovant, Inc. (IMVT) | 100 | 445.2 | +345.2% |
Price return only. Dividends and distributions are not included.
Quick Verdict: ACLX vs DBVT vs SANA vs IMVT
Each card shows where this stock fits in a portfolio — not just who wins on paper.
ACLX carries the broadest edge in this set and is the clearest fit for growth exposure and long-term compounding.
- Rev growth -79.4%, EPS growth -103.5%
- 5.8% 10Y total return vs IMVT's 173.6%
- +117.4% vs IMVT's +96.1%
- -36.2% ROA vs DBVT's -89.0%
DBVT is the #2 pick in this set and the best alternative if income & stability is your priority.
- Dividend streak 0 yrs, beta 1.26
- Beta 1.26 vs SANA's 2.69, lower leverage
SANA is the clearest fit if your priority is growth.
- 22.6% revenue growth vs DBVT's -100.0%
IMVT is the clearest fit if your priority is sleep-well-at-night and defensive.
- Lower volatility, beta 1.37, Low D/E 0.0%, current ratio 11.16x
- Beta 1.37, current ratio 11.16x
- 3.2% margin vs ACLX's -10.3%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 22.6% revenue growth vs DBVT's -100.0% | |
| Quality / Margins | 3.2% margin vs ACLX's -10.3% | |
| Stability / Safety | Beta 1.26 vs SANA's 2.69, lower leverage | |
| Dividends | Tie | None of these 4 stocks pay a meaningful dividend |
| Momentum (1Y) | +117.4% vs IMVT's +96.1% | |
| Efficiency (ROA) | -36.2% ROA vs DBVT's -89.0% |
ACLX vs DBVT vs SANA vs IMVT — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
ACLX leads in 2 of 6 categories
DBVT leads 1 • SANA leads 0 • IMVT leads 0 • 2 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
DBVT leads this category, winning 1 of 1 comparable metric.
Income & Cash Flow (Last 12 Months)
ACLX and IMVT operate at a comparable scale, with $22M and $0 in trailing revenue.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $22M | $0 | $0 | $0 |
| EBITDAEarnings before interest/tax | -$246M | -$112M | -$225M | -$487M |
| Net IncomeAfter-tax profit | -$229M | -$168M | -$234M | -$464M |
| Free Cash FlowCash after capex | -$213M | -$151M | -$159M | -$423M |
| Gross MarginGross profit ÷ Revenue | -64.8% | — | — | — |
| Operating MarginEBIT ÷ Revenue | -11.4% | — | — | — |
| Net MarginNet income ÷ Revenue | -10.3% | — | — | — |
| FCF MarginFCF ÷ Revenue | -9.5% | — | — | — |
| Rev. Growth (YoY)Latest quarter vs prior year | -89.2% | — | — | — |
| EPS Growth (YoY)Latest quarter vs prior year | -13.6% | +91.5% | +36.0% | +19.7% |
Valuation Metrics
Evenly matched — ACLX and DBVT each lead in 1 of 2 comparable metrics.
Valuation Metrics
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $6.7B | $1712.35T | $918M | $5.5B |
| Enterprise ValueMkt cap + debt − cash | $6.7B | $1712.35T | $885M | $4.8B |
| Trailing P/EPrice ÷ TTM EPS | -28.27x | -0.76x | -3.02x | -9.97x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | — |
| Price / SalesMarket cap ÷ Revenue | 302.09x | — | — | — |
| Price / BookPrice ÷ Book value/share | 16.10x | 0.66x | 3.23x | 5.83x |
| Price / FCFMarket cap ÷ FCF | — | — | — | — |
Profitability & Efficiency
Evenly matched — ACLX and IMVT each lead in 4 of 9 comparable metrics.
Profitability & Efficiency
IMVT delivers a -47.1% return on equity — every $100 of shareholder capital generates $-47 in annual profit, vs $-130 for DBVT. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to SANA's 0.38x. On the Piotroski fundamental quality scale (0–9), DBVT scores 4/9 vs ACLX's 1/9, reflecting mixed financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -55.4% | -130.2% | -120.0% | -47.1% |
| ROA (TTM)Return on assets | -36.2% | -89.0% | -53.8% | -44.1% |
| ROICReturn on invested capital | -46.2% | — | -86.1% | — |
| ROCEReturn on capital employed | -46.6% | -145.7% | -57.0% | -66.1% |
| Piotroski ScoreFundamental quality 0–9 | 1 | 4 | 2 | 2 |
| Debt / EquityFinancial leverage | 0.24x | 0.13x | 0.38x | 0.00x |
| Net DebtTotal debt minus cash | $16M | -$172M | -$33M | -$714M |
| Cash & Equiv.Liquid assets | $80M | $194M | $128M | $714M |
| Total DebtShort + long-term debt | $96M | $22M | $94M | $98,000 |
| Interest CoverageEBIT ÷ Interest expense | -8.45x | -189.82x | — | — |
Total Returns (Dividends Reinvested)
ACLX leads this category, winning 6 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ACLX five years ago would be worth $68,494 today (with dividends reinvested), compared to $1,926 for SANA. Over the past 12 months, ACLX leads with a +117.4% total return vs IMVT's +96.1%. The 3-year compound annual growth rate (CAGR) favors ACLX at 38.6% vs SANA's -14.2% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | +81.7% | +4.9% | -16.5% | +5.1% |
| 1-Year ReturnPast 12 months | +117.4% | +110.4% | +105.9% | +96.1% |
| 3-Year ReturnCumulative with dividends | +166.2% | +19.7% | -36.8% | +40.9% |
| 5-Year ReturnCumulative with dividends | +584.9% | -69.1% | -80.7% | +62.4% |
| 10-Year ReturnCumulative with dividends | +584.9% | -87.0% | -90.0% | +173.6% |
| CAGR (3Y)Annualised 3-year return | +38.6% | +6.2% | -14.2% | +12.1% |
Risk & Volatility
ACLX leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
ACLX is the less volatile stock with a -0.34 beta — it tends to amplify market swings less than SANA's 2.69 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ACLX currently trades 99.9% from its 52-week high vs SANA's 53.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | -0.34x | 1.26x | 2.69x | 1.37x |
| 52-Week HighHighest price in past year | $115.13 | $26.18 | $6.55 | $30.09 |
| 52-Week LowLowest price in past year | $47.86 | $7.53 | $1.60 | $13.36 |
| % of 52W HighCurrent price vs 52-week peak | +99.9% | +76.3% | +53.4% | +90.5% |
| RSI (14)Momentum oscillator 0–100 | 79.9 | 48.1 | 59.0 | 60.2 |
| Avg Volume (50D)Average daily shares traded | 1.6M | 252K | 3.1M | 1.4M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: ACLX as "Hold", DBVT as "Buy", SANA as "Buy", IMVT as "Buy". Consensus price targets imply 147.7% upside for SANA (target: $9) vs -2.3% for ACLX (target: $112).
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Hold | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $112.45 | $46.33 | $8.67 | $45.50 |
| # AnalystsCovering analysts | 18 | 15 | 11 | 23 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | 0 | — | — |
| Dividend / ShareAnnual DPS | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | 0.0% |
ACLX leads in 2 of 6 categories (Total Returns, Risk & Volatility). DBVT leads in 1 (Income & Cash Flow). 2 tied.
ACLX vs DBVT vs SANA vs IMVT: Key Questions Answered
8 questions · data-driven answers · updated daily
01Is ACLX or DBVT or SANA or IMVT a better buy right now?
Analysts rate DBV Technologies S.
A. (DBVT) a "Buy" — based on 15 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — ACLX or DBVT or SANA or IMVT?
Over the past 5 years, Arcellx, Inc.
(ACLX) delivered a total return of +584. 9%, compared to -80. 7% for Sana Biotechnology, Inc. (SANA). Over 10 years, the gap is even starker: ACLX returned +584. 9% versus SANA's -90. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — ACLX or DBVT or SANA or IMVT?
By beta (market sensitivity over 5 years), Arcellx, Inc.
(ACLX) is the lower-risk stock at -0. 34β versus Sana Biotechnology, Inc. 's 2. 69β — meaning SANA is approximately -894% more volatile than ACLX relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 38% for Sana Biotechnology, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — ACLX or DBVT or SANA or IMVT?
On earnings-per-share growth, the picture is similar: Sana Biotechnology, Inc.
grew EPS 20. 5% year-over-year, compared to -347. 5% for DBV Technologies S. A.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — ACLX or DBVT or SANA or IMVT?
DBV Technologies S.
A. (DBVT) is the more profitable company, earning 0. 0% net margin versus -1027. 3% for Arcellx, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: DBVT leads at 0. 0% versus -1135. 6% for ACLX. At the gross margin level — before operating expenses — ACLX leads at 70. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — ACLX or DBVT or SANA or IMVT?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is ACLX or DBVT or SANA or IMVT better for a retirement portfolio?
For long-horizon retirement investors, Arcellx, Inc.
(ACLX) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β -0. 34), +584. 9% 10Y return). Sana Biotechnology, Inc. (SANA) carries a higher beta of 2. 69 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ACLX: +584. 9%, SANA: -90. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between ACLX and DBVT and SANA and IMVT?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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