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ACON vs XTNT vs GKOS vs NVCR vs ZBH

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
ACON
Aclarion, Inc.

Medical - Healthcare Information Services

HealthcareNASDAQ • US
Market Cap$3M
5Y Perf.-100.0%
XTNT
Xtant Medical Holdings, Inc.

Medical - Devices

HealthcareAMEX • US
Market Cap$73M
5Y Perf.-19.9%
GKOS
Glaukos Corporation

Medical - Devices

HealthcareNYSE • US
Market Cap$7.81B
5Y Perf.+182.3%
NVCR
NovoCure Limited

Medical - Instruments & Supplies

HealthcareNASDAQ • JE
Market Cap$2.04B
5Y Perf.-76.6%
ZBH
Zimmer Biomet Holdings, Inc.

Medical - Devices

HealthcareNYSE • US
Market Cap$16.12B
5Y Perf.-31.8%

ACON vs XTNT vs GKOS vs NVCR vs ZBH — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
ACON logoACON
XTNT logoXTNT
GKOS logoGKOS
NVCR logoNVCR
ZBH logoZBH
IndustryMedical - Healthcare Information ServicesMedical - DevicesMedical - DevicesMedical - Instruments & SuppliesMedical - Devices
Market Cap$3M$73M$7.81B$2.04B$16.12B
Revenue (TTM)$75.73B$133M$551M$674M$8.41B
Net Income (TTM)$-7.23T$2M$-189M$-173M$761M
Gross Margin9.0%62.0%78.1%75.2%70.0%
Operating Margin-93.1%4.8%-15.6%-27.2%15.6%
Forward P/E9.7x
Total Debt$0.00$35M$140M$290M$7.52B
Cash & Equiv.$12.02T$6M$91M$103M$592M

ACON vs XTNT vs GKOS vs NVCR vs ZBHLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

ACON
XTNT
GKOS
NVCR
ZBH
StockApr 22May 26Return
Aclarion, Inc. (ACON)1000.0-100.0%
Xtant Medical Holdi… (XTNT)10080.1-19.9%
Glaukos Corporation (GKOS)100282.3+182.3%
NovoCure Limited (NVCR)10023.4-76.6%
Zimmer Biomet Holdi… (ZBH)10068.2-31.8%

Price return only. Dividends and distributions are not included.

Quick Verdict: ACON vs XTNT vs GKOS vs NVCR vs ZBH

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: ZBH leads in 3 of 6 categories (5-stock set), making it the strongest pick for profitability and margin quality and capital preservation and lower volatility. Aclarion, Inc. is the stronger pick specifically for growth and revenue expansion and dividend income and shareholder returns. GKOS also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
ACON
Aclarion, Inc.
The Income Pick

ACON is the #2 pick in this set and the best alternative if income & stability and growth exposure is your priority.

  • Dividend streak 1 yrs, beta 1.04, yield 100.0%
  • Rev growth 1000K%, EPS growth 99.8%, 3Y rev CAGR 106.8%
  • Beta 1.04, yield 100.0%, current ratio 14.81x
  • 1000K% revenue growth vs ZBH's 7.2%
Best for: income & stability and growth exposure
XTNT
Xtant Medical Holdings, Inc.
The Lower-Volatility Pick

XTNT lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
GKOS
Glaukos Corporation
The Long-Run Compounder

GKOS ranks third and is worth considering specifically for long-term compounding.

  • 454.5% 10Y total return vs ZBH's -18.8%
  • +47.5% vs ACON's -53.5%
Best for: long-term compounding
NVCR
NovoCure Limited
The Healthcare Pick

Among these 5 stocks, NVCR doesn't own a clear edge in any measured category.

Best for: healthcare exposure
ZBH
Zimmer Biomet Holdings, Inc.
The Defensive Pick

ZBH carries the broadest edge in this set and is the clearest fit for sleep-well-at-night.

  • Lower volatility, beta 0.60, Low D/E 59.2%, current ratio 1.98x
  • 9.1% margin vs ACON's -95.5%
  • Beta 0.60 vs NVCR's 2.15, lower leverage
  • 3.3% ROA vs ACON's -211.6%, ROIC 5.4% vs -12.9%
Best for: sleep-well-at-night
See the full category breakdown
CategoryWinnerWhy
GrowthACON logoACON1000K% revenue growth vs ZBH's 7.2%
Quality / MarginsZBH logoZBH9.1% margin vs ACON's -95.5%
Stability / SafetyZBH logoZBHBeta 0.60 vs NVCR's 2.15, lower leverage
DividendsACON logoACON100.0% yield, 1-year raise streak, vs ZBH's 1.2%, (3 stocks pay no dividend)
Momentum (1Y)GKOS logoGKOS+47.5% vs ACON's -53.5%
Efficiency (ROA)ZBH logoZBH3.3% ROA vs ACON's -211.6%, ROIC 5.4% vs -12.9%

ACON vs XTNT vs GKOS vs NVCR vs ZBH — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

ACONAclarion, Inc.

Segment breakdown not available.

XTNTXtant Medical Holdings, Inc.
FY 2024
Orthobiologics
56.6%$66M
Spinal Implant
42.1%$49M
License Revenue
1.3%$2M
GKOSGlaukos Corporation
FY 2019
Glaucoma
97.5%$231M
Corneal Health
2.5%$6M
NVCRNovoCure Limited

Segment breakdown not available.

ZBHZimmer Biomet Holdings, Inc.
FY 2025
Knees
43.9%$3.3B
S E T
28.4%$2.2B
Hips
27.7%$2.1B

ACON vs XTNT vs GKOS vs NVCR vs ZBH — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLACONLAGGINGNVCR

Income & Cash Flow (Last 12 Months)

ZBH leads this category, winning 3 of 6 comparable metrics.

ACON is the larger business by revenue, generating $75.7B annually — 569.0x XTNT's $133M. ZBH is the more profitable business, keeping 9.1% of every revenue dollar as net income compared to ACON's -95.5%. On growth, ACON holds the edge at +999999.0% YoY revenue growth, suggesting stronger near-term business momentum.

MetricACON logoACONAclarion, Inc.XTNT logoXTNTXtant Medical Hol…GKOS logoGKOSGlaukos Corporati…NVCR logoNVCRNovoCure LimitedZBH logoZBHZimmer Biomet Hol…
RevenueTrailing 12 months$75.7B$133M$551M$674M$8.4B
EBITDAEarnings before interest/tax-$7.05T$11M-$40M-$165M$2.3B
Net IncomeAfter-tax profit-$7.23T$2M-$189M-$173M$761M
Free Cash FlowCash after capex-$7.16T$5M-$18M-$48M$1.8B
Gross MarginGross profit ÷ Revenue+9.0%+62.0%+78.1%+75.2%+70.0%
Operating MarginEBIT ÷ Revenue-93.1%+4.8%-15.6%-27.2%+15.6%
Net MarginNet income ÷ Revenue-95.5%+1.3%-34.3%-25.7%+9.1%
FCF MarginFCF ÷ Revenue-94.6%+3.9%-3.4%-7.1%+21.8%
Rev. Growth (YoY)Latest quarter vs prior year+999999.0%+19.0%+41.2%+12.3%+9.3%
EPS Growth (YoY)Latest quarter vs prior year+99.9%+123.7%-6.3%-100.0%+34.1%
ZBH leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

ACON leads this category, winning 2 of 3 comparable metrics.
MetricACON logoACONAclarion, Inc.XTNT logoXTNTXtant Medical Hol…GKOS logoGKOSGlaukos Corporati…NVCR logoNVCRNovoCure LimitedZBH logoZBHZimmer Biomet Hol…
Market CapShares × price$3M$73M$7.8B$2.0B$16.1B
Enterprise ValueMkt cap + debt − cash-$12.02T$102M$7.9B$2.2B$23.0B
Trailing P/EPrice ÷ TTM EPS-0.23x-4.33x-40.71x-14.66x23.19x
Forward P/EPrice ÷ next-FY EPS est.9.71x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple9.38x
Price / SalesMarket cap ÷ Revenue0.00x0.62x15.40x3.11x1.96x
Price / BookPrice ÷ Book value/share0.00x1.62x11.64x5.86x1.29x
Price / FCFMarket cap ÷ FCF10.95x
ACON leads this category, winning 2 of 3 comparable metrics.

Profitability & Efficiency

ZBH leads this category, winning 6 of 9 comparable metrics.

ZBH delivers a 5.8% return on equity — every $100 of shareholder capital generates $6 in annual profit, vs $-2 for ACON. GKOS carries lower financial leverage with a 0.21x debt-to-equity ratio, signaling a more conservative balance sheet compared to NVCR's 0.85x. On the Piotroski fundamental quality scale (0–9), NVCR scores 5/9 vs XTNT's 2/9, reflecting solid financial health.

MetricACON logoACONAclarion, Inc.XTNT logoXTNTXtant Medical Hol…GKOS logoGKOSGlaukos Corporati…NVCR logoNVCRNovoCure LimitedZBH logoZBHZimmer Biomet Hol…
ROE (TTM)Return on equity-2.3%+3.8%-26.5%-50.8%+5.8%
ROA (TTM)Return on assets-2.1%+1.8%-20.1%-16.5%+3.3%
ROICReturn on invested capital-12.9%-12.8%-9.2%-16.4%+5.4%
ROCEReturn on capital employed-109.9%-17.9%-10.3%-28.9%+6.9%
Piotroski ScoreFundamental quality 0–942355
Debt / EquityFinancial leverage0.82x0.21x0.85x0.59x
Net DebtTotal debt minus cash-$12.02T$29M$49M$187M$6.9B
Cash & Equiv.Liquid assets$12.02T$6M$91M$103M$592M
Total DebtShort + long-term debt$0$35M$140M$290M$7.5B
Interest CoverageEBIT ÷ Interest expense1.55x-18.69x-96.80x4.08x
ZBH leads this category, winning 6 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

GKOS leads this category, winning 5 of 6 comparable metrics.

A $10,000 investment in GKOS five years ago would be worth $17,474 today (with dividends reinvested), compared to $0 for ACON. Over the past 12 months, GKOS leads with a +47.5% total return vs ACON's -53.5%. The 3-year compound annual growth rate (CAGR) favors GKOS at 31.5% vs ACON's -96.9% — a key indicator of consistent wealth creation.

MetricACON logoACONAclarion, Inc.XTNT logoXTNTXtant Medical Hol…GKOS logoGKOSGlaukos Corporati…NVCR logoNVCRNovoCure LimitedZBH logoZBHZimmer Biomet Hol…
YTD ReturnYear-to-date-36.0%-30.7%+20.6%+36.4%-8.3%
1-Year ReturnPast 12 months-53.5%-3.2%+47.5%+2.6%-12.4%
3-Year ReturnCumulative with dividends-100.0%-20.0%+127.6%-74.2%-38.0%
5-Year ReturnCumulative with dividends-100.0%-68.9%+74.7%-90.2%-47.8%
10-Year ReturnCumulative with dividends-100.0%-98.0%+454.5%+38.5%-18.8%
CAGR (3Y)Annualised 3-year return-96.9%-7.2%+31.5%-36.4%-14.7%
GKOS leads this category, winning 5 of 6 comparable metrics.

Risk & Volatility

Evenly matched — GKOS and ZBH each lead in 1 of 2 comparable metrics.

ZBH is the less volatile stock with a 0.60 beta — it tends to amplify market swings less than NVCR's 2.15 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. GKOS currently trades 91.0% from its 52-week high vs ACON's 26.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricACON logoACONAclarion, Inc.XTNT logoXTNTXtant Medical Hol…GKOS logoGKOSGlaukos Corporati…NVCR logoNVCRNovoCure LimitedZBH logoZBHZimmer Biomet Hol…
Beta (5Y)Sensitivity to S&P 5001.04x0.67x1.16x2.15x0.60x
52-Week HighHighest price in past year$12.03$0.95$146.75$20.06$108.29
52-Week LowLowest price in past year$2.34$0.44$73.16$9.82$79.83
% of 52W HighCurrent price vs 52-week peak+26.5%+54.7%+91.0%+89.2%+76.0%
RSI (14)Momentum oscillator 0–10044.558.661.570.936.2
Avg Volume (50D)Average daily shares traded102K147K674K1.4M2.2M
Evenly matched — GKOS and ZBH each lead in 1 of 2 comparable metrics.

Analyst Outlook

ACON leads this category, winning 2 of 2 comparable metrics.

Analyst consensus: GKOS as "Buy", NVCR as "Buy", ZBH as "Hold". Consensus price targets imply 87.3% upside for NVCR (target: $34) vs 9.8% for GKOS (target: $147). For income investors, ACON offers the higher dividend yield at 100.00% vs ZBH's 1.16%.

MetricACON logoACONAclarion, Inc.XTNT logoXTNTXtant Medical Hol…GKOS logoGKOSGlaukos Corporati…NVCR logoNVCRNovoCure LimitedZBH logoZBHZimmer Biomet Hol…
Analyst RatingConsensus buy/hold/sellBuyBuyHold
Price TargetConsensus 12-month target$146.67$33.50$96.33
# AnalystsCovering analysts241542
Dividend YieldAnnual dividend ÷ price+100.0%+1.2%
Dividend StreakConsecutive years of raises10
Dividend / ShareAnnual DPS$10196.68$0.96
Buyback YieldShare repurchases ÷ mkt cap+44.6%0.0%0.0%0.0%+3.0%
ACON leads this category, winning 2 of 2 comparable metrics.
Key Takeaway

ZBH leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). ACON leads in 2 (Valuation Metrics, Analyst Outlook). 1 tied.

Best OverallAclarion, Inc. (ACON)Leads 2 of 6 categories
Loading custom metrics...

ACON vs XTNT vs GKOS vs NVCR vs ZBH: Key Questions Answered

9 questions · data-driven answers · updated daily

01

Is ACON or XTNT or GKOS or NVCR or ZBH a better buy right now?

For growth investors, Aclarion, Inc.

(ACON) is the stronger pick with 999999% revenue growth year-over-year, versus 7. 2% for Zimmer Biomet Holdings, Inc. (ZBH). Zimmer Biomet Holdings, Inc. (ZBH) offers the better valuation at 23. 2x trailing P/E (9. 7x forward), making it the more compelling value choice. Analysts rate Glaukos Corporation (GKOS) a "Buy" — based on 24 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — ACON or XTNT or GKOS or NVCR or ZBH?

Over the past 5 years, Glaukos Corporation (GKOS) delivered a total return of +74.

7%, compared to -100. 0% for Aclarion, Inc. (ACON). Over 10 years, the gap is even starker: GKOS returned +454. 5% versus ACON's -100. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — ACON or XTNT or GKOS or NVCR or ZBH?

By beta (market sensitivity over 5 years), Zimmer Biomet Holdings, Inc.

(ZBH) is the lower-risk stock at 0. 60β versus NovoCure Limited's 2. 15β — meaning NVCR is approximately 260% more volatile than ZBH relative to the S&P 500. On balance sheet safety, Glaukos Corporation (GKOS) carries a lower debt/equity ratio of 21% versus 85% for NovoCure Limited — giving it more financial flexibility in a downturn.

04

Which is growing faster — ACON or XTNT or GKOS or NVCR or ZBH?

By revenue growth (latest reported year), Aclarion, Inc.

(ACON) is pulling ahead at 999999% versus 7. 2% for Zimmer Biomet Holdings, Inc. (ZBH). On earnings-per-share growth, the picture is similar: Aclarion, Inc. grew EPS 99. 8% year-over-year, compared to -19. 9% for Zimmer Biomet Holdings, Inc.. Over a 3-year CAGR, ACON leads at 106. 8% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — ACON or XTNT or GKOS or NVCR or ZBH?

Zimmer Biomet Holdings, Inc.

(ZBH) is the more profitable company, earning 8. 6% net margin versus -95. 5% for Aclarion, Inc. — meaning it keeps 8. 6% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ZBH leads at 16. 5% versus -93. 1% for ACON. At the gross margin level — before operating expenses — GKOS leads at 77. 5%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is ACON or XTNT or GKOS or NVCR or ZBH more undervalued right now?

Analyst consensus price targets imply the most upside for NVCR: 87.

3% to $33. 50.

07

Which pays a better dividend — ACON or XTNT or GKOS or NVCR or ZBH?

In this comparison, ACON (100.

0% yield), ZBH (1. 2% yield) pay a dividend. XTNT, GKOS, NVCR do not pay a meaningful dividend and should not be held primarily for income.

08

Is ACON or XTNT or GKOS or NVCR or ZBH better for a retirement portfolio?

For long-horizon retirement investors, Zimmer Biomet Holdings, Inc.

(ZBH) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 60), 1. 2% yield). NovoCure Limited (NVCR) carries a higher beta of 2. 15 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ZBH: -18. 8%, NVCR: +38. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between ACON and XTNT and GKOS and NVCR and ZBH?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: ACON is a small-cap high-growth stock; XTNT is a small-cap high-growth stock; GKOS is a small-cap high-growth stock; NVCR is a small-cap quality compounder stock; ZBH is a mid-cap quality compounder stock. ACON, ZBH pay a dividend while XTNT, GKOS, NVCR do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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ACON

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  • Revenue Growth > 49999950%
  • Dividend Yield > 40.0%
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XTNT

High-Growth Disruptor

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 9%
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GKOS

High-Growth Disruptor

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 20%
  • Gross Margin > 46%
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NVCR

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  • Sector: Healthcare
  • Market Cap > $100B
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ZBH

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  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 5%
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