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AEMD vs DBVT vs ADMA vs AGEN vs ALKS
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
Biotechnology
AEMD vs DBVT vs ADMA vs AGEN vs ALKS — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Medical - Devices | Biotechnology | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $351K | $1690.08T | $1.89B | $135M | $5.83B |
| Revenue (TTM) | $0.00 | $0.00 | $510M | $114M | $1.56B |
| Net Income (TTM) | $-2.03B | $-168M | $165M | $115K | $153M |
| Gross Margin | — | — | 61.3% | 35.7% | 65.4% |
| Operating Margin | — | — | 42.1% | -17.7% | 12.3% |
| Forward P/E | — | — | 9.7x | 2.9x | 24.5x |
| Total Debt | $650K | $22M | $80M | $10M | $70M |
| Cash & Equiv. | $6M | $194M | $88M | $3M | $1.12B |
AEMD vs DBVT vs ADMA vs AGEN vs ALKS — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Aethlon Medical, In… (AEMD) | 100 | 0.2 | -99.8% |
| DBV Technologies S.… (DBVT) | 100 | 40.7 | -59.3% |
| ADMA Biologics, Inc. (ADMA) | 100 | 248.3 | +148.3% |
| Agenus Inc. (AGEN) | 100 | 5.1 | -94.9% |
| Alkermes plc (ALKS) | 100 | 213.9 | +113.9% |
Price return only. Dividends and distributions are not included.
Quick Verdict: AEMD vs DBVT vs ADMA vs AGEN vs ALKS
Each card shows where this stock fits in a portfolio — not just who wins on paper.
Among these 5 stocks, AEMD doesn't own a clear edge in any measured category.
DBVT is the #2 pick in this set and the best alternative if momentum is your priority.
- +100.5% vs AEMD's -92.4%
ADMA carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- Dividend streak 1 yrs, beta 1.25
- Rev growth 19.6%, EPS growth -25.9%, 3Y rev CAGR 49.0%
- 34.8% 10Y total return vs ALKS's -12.0%
- Beta 1.25, current ratio 6.71x
AGEN ranks third and is worth considering specifically for value.
- Lower P/E (2.9x vs 9.7x)
ALKS is the clearest fit if your priority is sleep-well-at-night.
- Lower volatility, beta 1.00, Low D/E 3.8%, current ratio 3.55x
- Beta 1.00 vs AGEN's 2.58
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 19.6% revenue growth vs AEMD's -177.7% | |
| Value | Lower P/E (2.9x vs 9.7x) | |
| Quality / Margins | 32.4% margin vs AGEN's 0.1% | |
| Stability / Safety | Beta 1.00 vs AGEN's 2.58 | |
| Dividends | Tie | None of these 5 stocks pay a meaningful dividend |
| Momentum (1Y) | +100.5% vs AEMD's -92.4% | |
| Efficiency (ROA) | 27.4% ROA vs DBVT's -89.0% |
AEMD vs DBVT vs ADMA vs AGEN vs ALKS — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
AEMD vs DBVT vs ADMA vs AGEN vs ALKS — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
ALKS leads in 2 of 6 categories
ADMA leads 2 • AGEN leads 1 • AEMD leads 0 • DBVT leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
ALKS leads this category, winning 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
ALKS and DBVT operate at a comparable scale, with $1.6B and $0 in trailing revenue. ADMA is the more profitable business, keeping 32.4% of every revenue dollar as net income compared to AGEN's 0.1%. On growth, ALKS holds the edge at +28.2% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $0 | $510M | $114M | $1.6B |
| EBITDAEarnings before interest/tax | -$5M | -$112M | $221M | -$10M | $212M |
| Net IncomeAfter-tax profit | -$2.0B | -$168M | $165M | $115,000 | $153M |
| Free Cash FlowCash after capex | -$5.3B | -$151M | $108M | -$159M | $392M |
| Gross MarginGross profit ÷ Revenue | — | — | +61.3% | +35.7% | +65.4% |
| Operating MarginEBIT ÷ Revenue | — | — | +42.1% | -17.7% | +12.3% |
| Net MarginNet income ÷ Revenue | — | — | +32.4% | +0.1% | +9.8% |
| FCF MarginFCF ÷ Revenue | — | — | +21.2% | -139.1% | +25.1% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | — | -0.3% | +27.5% | +28.2% |
| EPS Growth (YoY)Latest quarter vs prior year | +71.5% | +91.5% | +72.7% | +85.3% | -4.1% |
Valuation Metrics
AGEN leads this category, winning 3 of 6 comparable metrics.
Valuation Metrics
At 13.6x trailing earnings, ADMA trades at a 44% valuation discount to ALKS's 24.5x P/E. On an enterprise value basis, ADMA's 9.5x EV/EBITDA is more attractive than ALKS's 17.0x.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $351,189 | $1690.08T | $1.9B | $135M | $5.8B |
| Enterprise ValueMkt cap + debt − cash | -$5M | $1690.08T | $1.9B | $142M | $4.8B |
| Trailing P/EPrice ÷ TTM EPS | -0.03x | -0.75x | 13.62x | -1123.53x | 24.47x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | 9.69x | 2.94x | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | 9.45x | — | 17.01x |
| Price / SalesMarket cap ÷ Revenue | — | — | 3.71x | 1.18x | 3.95x |
| Price / BookPrice ÷ Book value/share | 0.07x | 0.65x | 4.19x | — | 3.25x |
| Price / FCFMarket cap ÷ FCF | — | — | 68.06x | — | 12.14x |
Profitability & Efficiency
ADMA leads this category, winning 5 of 9 comparable metrics.
Profitability & Efficiency
ADMA delivers a 39.0% return on equity — every $100 of shareholder capital generates $39 in annual profit, vs $-130 for DBVT. ALKS carries lower financial leverage with a 0.04x debt-to-equity ratio, signaling a more conservative balance sheet compared to ADMA's 0.17x. On the Piotroski fundamental quality scale (0–9), ALKS scores 7/9 vs AEMD's 3/9, reflecting strong financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -30.2% | -130.2% | +39.0% | — | +8.8% |
| ROA (TTM)Return on assets | -25.2% | -89.0% | +27.4% | +0.1% | +5.4% |
| ROICReturn on invested capital | -9.1% | — | +36.0% | — | +18.9% |
| ROCEReturn on capital employed | -157.3% | -145.7% | +38.8% | — | +14.2% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 4 | 5 | 6 | 7 |
| Debt / EquityFinancial leverage | 0.13x | 0.13x | 0.17x | — | 0.04x |
| Net DebtTotal debt minus cash | -$5M | -$172M | -$8M | $7M | -$1.0B |
| Cash & Equiv.Liquid assets | $6M | $194M | $88M | $3M | $1.1B |
| Total DebtShort + long-term debt | $649,751 | $22M | $80M | $10M | $70M |
| Interest CoverageEBIT ÷ Interest expense | -939.14x | -189.82x | 50.85x | 1.11x | 32.30x |
Total Returns (Dividends Reinvested)
ADMA leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ADMA five years ago would be worth $48,922 today (with dividends reinvested), compared to $17 for AEMD. Over the past 12 months, DBVT leads with a +100.5% total return vs AEMD's -92.4%. The 3-year compound annual growth rate (CAGR) favors ADMA at 32.7% vs AEMD's -80.0% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -20.2% | +3.6% | -54.3% | +18.3% | +23.8% |
| 1-Year ReturnPast 12 months | -92.4% | +100.5% | -61.5% | +25.7% | +15.2% |
| 3-Year ReturnCumulative with dividends | -99.2% | +18.1% | +133.4% | -88.0% | +13.2% |
| 5-Year ReturnCumulative with dividends | -99.8% | -68.3% | +389.2% | -93.7% | +61.7% |
| 10-Year ReturnCumulative with dividends | -100.0% | -87.1% | +34.8% | -94.2% | -12.0% |
| CAGR (3Y)Annualised 3-year return | -80.0% | +5.7% | +32.7% | -50.7% | +4.2% |
Risk & Volatility
ALKS leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
ALKS is the less volatile stock with a 1.00 beta — it tends to amplify market swings less than AGEN's 2.58 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ALKS currently trades 95.6% from its 52-week high vs AEMD's 6.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.41x | 1.26x | 1.25x | 2.58x | 1.00x |
| 52-Week HighHighest price in past year | $35.20 | $26.18 | $22.73 | $7.34 | $36.60 |
| 52-Week LowLowest price in past year | $1.36 | $7.53 | $7.21 | $2.71 | $25.17 |
| % of 52W HighCurrent price vs 52-week peak | +6.4% | +75.3% | +35.9% | +52.0% | +95.6% |
| RSI (14)Momentum oscillator 0–100 | 54.2 | 47.4 | 26.0 | 46.1 | 60.5 |
| Avg Volume (50D)Average daily shares traded | 47K | 252K | 7.4M | 822K | 2.2M |
Analyst Outlook
Evenly matched — ADMA and AGEN each lead in 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: DBVT as "Buy", ADMA as "Buy", AGEN as "Buy", ALKS as "Buy". Consensus price targets imply 157.0% upside for ADMA (target: $21) vs 31.5% for ALKS (target: $46).
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | — | $46.33 | $21.00 | $7.33 | $46.00 |
| # AnalystsCovering analysts | — | 15 | 10 | 11 | 28 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | 0 | 1 | 1 | 0 |
| Dividend / ShareAnnual DPS | — | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | +1.7% | +0.1% | +0.5% |
ALKS leads in 2 of 6 categories (Income & Cash Flow, Risk & Volatility). ADMA leads in 2 (Profitability & Efficiency, Total Returns). 1 tied.
AEMD vs DBVT vs ADMA vs AGEN vs ALKS: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is AEMD or DBVT or ADMA or AGEN or ALKS a better buy right now?
For growth investors, ADMA Biologics, Inc.
(ADMA) is the stronger pick with 19. 6% revenue growth year-over-year, versus -5. 2% for Alkermes plc (ALKS). ADMA Biologics, Inc. (ADMA) offers the better valuation at 13. 6x trailing P/E (9. 7x forward), making it the more compelling value choice. Analysts rate DBV Technologies S. A. (DBVT) a "Buy" — based on 15 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — AEMD or DBVT or ADMA or AGEN or ALKS?
On trailing P/E, ADMA Biologics, Inc.
(ADMA) is the cheapest at 13. 6x versus Alkermes plc at 24. 5x. On forward P/E, Agenus Inc. is actually cheaper at 2. 9x — notably different from the trailing picture, reflecting expected earnings growth.
03Which is the better long-term investment — AEMD or DBVT or ADMA or AGEN or ALKS?
Over the past 5 years, ADMA Biologics, Inc.
(ADMA) delivered a total return of +389. 2%, compared to -99. 8% for Aethlon Medical, Inc. (AEMD). Over 10 years, the gap is even starker: ADMA returned +34. 8% versus AEMD's -100. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — AEMD or DBVT or ADMA or AGEN or ALKS?
By beta (market sensitivity over 5 years), Alkermes plc (ALKS) is the lower-risk stock at 1.
00β versus Agenus Inc. 's 2. 58β — meaning AGEN is approximately 159% more volatile than ALKS relative to the S&P 500. On balance sheet safety, Alkermes plc (ALKS) carries a lower debt/equity ratio of 4% versus 17% for ADMA Biologics, Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — AEMD or DBVT or ADMA or AGEN or ALKS?
By revenue growth (latest reported year), ADMA Biologics, Inc.
(ADMA) is pulling ahead at 19. 6% versus -5. 2% for Alkermes plc (ALKS). On earnings-per-share growth, the picture is similar: Agenus Inc. grew EPS 100. 0% year-over-year, compared to -347. 5% for DBV Technologies S. A.. Over a 3-year CAGR, ADMA leads at 49. 0% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — AEMD or DBVT or ADMA or AGEN or ALKS?
ADMA Biologics, Inc.
(ADMA) is the more profitable company, earning 28. 8% net margin versus 0. 0% for DBV Technologies S. A. — meaning it keeps 28. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ADMA leads at 37. 5% versus -18. 0% for AGEN. At the gross margin level — before operating expenses — AGEN leads at 90. 3%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is AEMD or DBVT or ADMA or AGEN or ALKS more undervalued right now?
On forward earnings alone, Agenus Inc.
(AGEN) trades at 2. 9x forward P/E versus 9. 7x for ADMA Biologics, Inc. — 6. 7x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for ADMA: 157. 0% to $21. 00.
08Which pays a better dividend — AEMD or DBVT or ADMA or AGEN or ALKS?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
09Is AEMD or DBVT or ADMA or AGEN or ALKS better for a retirement portfolio?
For long-horizon retirement investors, Alkermes plc (ALKS) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1.
00)). Agenus Inc. (AGEN) carries a higher beta of 2. 58 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ALKS: -12. 0%, AGEN: -94. 2%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between AEMD and DBVT and ADMA and AGEN and ALKS?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: AEMD is a small-cap quality compounder stock; DBVT is a mega-cap quality compounder stock; ADMA is a small-cap high-growth stock; AGEN is a small-cap quality compounder stock; ALKS is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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