Agenus Inc. (AGEN) Revenue History
Annual and quarterly revenue from 1999 to present
AGEN Revenue Over Time (1999–2025)
AGEN Revenue Growth History
15 of 26 years with positive growth- FY1999 revenue growth
- N/A
- FY2000 revenue growth
- +342.6%
- FY2001 revenue growth
- +929.1%
- FY2002 revenue growth
- -25.1%
- FY2003 revenue growth
- +30.4%
- FY2004 revenue growth
- -84.1%
- FY2005 revenue growth
- -10.9%
- FY2006 revenue growth
- +9.9%
- FY2007 revenue growth
- +702.2%
- FY2008 revenue growth
- -52.3%
- FY2009 revenue growth
- +25.8%
- FY2010 revenue growth
- +0.8%
- FY2011 revenue growth
- -18.0%
- FY2012 revenue growth
- +479.2%
- FY2013 revenue growth
- -80.9%
- FY2014 revenue growth
- +129.1%
- FY2015 revenue growth
- +255.7%
- FY2016 revenue growth
- -9.0%
- FY2017 revenue growth
- +89.9%
- FY2018 revenue growth
- -14.2%
- FY2019 revenue growth
- +307.9%
- FY2020 revenue growth
- -41.2%
- FY2021 revenue growth
- +235.3%
- FY2022 revenue growth
- -66.8%
- FY2023 revenue growth
- +59.5%
- FY2024 revenue growth
- -33.8%
- FY2025 revenue growth
- +10.4%
| Quarter | Revenue | YoY |
|---|---|---|
| Q1 2026 | $33.7M | +40.2% |
| Q4 2025 | $34.2M | +27.5% |
| Q3 2025 | $30.2M | +20.4% |
| Q2 2025 | $25.7M | +9.3% |
| Q1 2025 | $24.1M | -14.1% |
| Q4 2024 | $26.8M | -68.0% |
| Q3 2024 | $25.1M | +3.3% |
| Q2 2024 | $23.5M | -7.1% |
Multi-year avg. share of annual revenue by fiscal quarter
Revenue Breakdown (FY 2025)
AGEN's revenue distribution by segment and geography for fiscal year 2025
By Product/Segment
By Geography
AGEN Revenue Analysis (1999–2025)
Current Revenue & Growth
As of June 21, 2026, Agenus Inc. (AGEN) generated trailing twelve-month (TTM) revenue of $123.9 million, reflecting explosive growth of +40.2% year-over-year. The most recent quarter (Q1 2026) recorded $33.7 million in revenue, down 1.4% sequentially.
Historical Growth Trajectory
AGEN's 5-year compound annual growth rate (CAGR) stands at +5.3%, indicating steady revenue expansion. The 3-year CAGR of +5.2% is in line with the 5-year average, suggesting consistent growth. Agenus Inc.'s highest annual revenue of $295.7 million was recorded in 2021.
Revenue by Segment
AGEN's revenue is primarily driven by Non Cash Royalty Revenue (99%), and Other (1%). With over half of revenue concentrated in Non Cash Royalty Revenue, the company has a focused business model while developing other growth vectors.
Peer Comparison
Compared to Healthcare sector peers — including NKTR (-36.2% YoY), INCY (+21.5% YoY), and EXEL (+3.3% YoY) — AGEN has outperformed the peer group in revenue growth. Compare AGEN vs NKTR →
AGEN Revenue vs Peers
Revenue metrics vs comparable public companies
| Company | TTM Revenue | YoY Growth | 5Y CAGR | Op. Margin | Compare |
|---|---|---|---|---|---|
| AGENCurrent | $124M | +40.2% | +5.3% | -18.0% | |
 NKTR | $55M | -36.2% | -18.4% | -236.8% | |
 INCY | $5.1B | +21.5% | +14.0% | 26.1% | |
 EXEL | $2.3B | +3.3% | +18.6% | 37.6% | |
 RCUS | $247M | +67.4% | +25.9% | -156.3% | |
 MGNX | $150M | +3.1% | +8.9% | -48.7% |
AGEN Historical Revenue Data (1999–2025)
| Year | Revenue | YoY % | Gross Profit | Gross Margin | Op. Income | Op. Margin |
|---|---|---|---|---|---|---|
| 2025 | $114.2M | +10.4% | $33.8M | 29.6% | $-20,556,000 | -18.0% |
| 2024 | $103.5M | -33.8% | $-52,551,000 | -50.8% | $-120,475,000 | -116.4% |
| 2023 | $156.3M | +59.5% | $-81,366,000 | -52.1% | $-159,549,000 | -102.1% |
| 2022 | $98.0M | -66.8% | $-99,235,000 | -101.2% | $-179,427,000 | -183.0% |
| 2021 | $295.7M | +235.3% | $113.6M | 38.4% | $25.7M | 8.7% |
| 2020 | $88.2M | -41.2% | $-56,796,000 | -64.4% | $-117,235,000 | -133.0% |
| 2019 | $150.0M | +307.9% | $-18,291,000 | -12.2% | $-70,137,000 | -46.7% |
| 2018 | $36.8M | -14.2% | $-87,816,808 | -238.7% | $-123,821,556 | -336.6% |
| 2017 | $42.9M | +89.9% | $-73,248,000 | -170.8% | $-103,801,000 | -242.1% |
| 2016 | $22.6M | -9.0% | $-72,398,000 | -320.7% | $-107,477,000 | -476.1% |
| 2015 | $24.8M | +255.7% | $-45,627,000 | -183.9% | $-80,701,000 | -325.2% |
| 2014 | $7.0M | +129.1% | $-15,372,000 | -220.3% | $-43,321,000 | -620.9% |
| 2013 | $3.0M | -80.9% | $-10,496,000 | -344.7% | $-24,980,000 | -820.4% |
| 2012 | $16.0M | +479.2% | $4.7M | 29.6% | $-6,741,000 | -42.2% |
| 2011 | $2.8M | -18.0% | $2.8M | 100.0% | $-19,086,806 | -692.6% |
Intrinsic Valuation
DCF models, multiple analysis, and analyst estimates.
Historical Returns
27+ years return with dividends reinvested.
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Peer Comparison
Compare growth, multiples, and margins vs sector.
AGEN — Frequently Asked Questions
Quick answers to the most common questions about buying AGEN stock.
Is AGEN's revenue growth accelerating or slowing?
AGEN revenue growth is accelerating. TTM revenue reached $124M, up +40.2% year-over-year — ahead of the 5-year CAGR of +5.3%. This indicates the business is expanding faster than its historical baseline.
What is AGEN's revenue history from 1999 to 2026?
Agenus Inc. (AGEN) revenue history spans 1999 to 2026. TTM revenue as of 2026 is $124M, growing at +40.2% YoY. The 5-year CAGR is +5.3%. Complete annual and quarterly revenue figures are available on this page, including gross profit, operating income, and margin trends.
What is AGEN's long-term revenue growth rate (CAGR)?
Agenus Inc.'s 5-year revenue CAGR of +5.3% reflects the sustained nature of its business expansion. As of 2026, the current YoY growth rate of +40.2% is above this long-term average. CAGR is the most reliable measure of sustained revenue momentum for AGEN.
Why does AGEN's quarterly revenue fluctuate?
AGEN quarterly revenue can fluctuate significantly between periods. A quarter-over-quarter (QoQ) change does not always indicate a trend; comparing the same quarter year-over-year (YoY) is a more reliable signal for underlying growth. Agenus Inc.'s revenue data from 1999 to 2026 shows full historical quarterly detail on this page.
How is AGEN's revenue distributed by segment?
AGEN reports revenue broken down by product line and geographic region. The segment breakdown on this page shows which business units contribute the most to total revenue as of the latest fiscal year. Concentration in a single segment above 50% indicates category dependence, while a diversified mix signals more resilient revenue streams.
How does AGEN's revenue compare to industry peers?
Agenus Inc. (AGEN) with TTM revenue of $124M and +40.2% YoY growth can be benchmarked against sector peers using the comparison table on this page. Revenue growth relative to peers indicates market share gains or losses. The peer section shows TTM revenue, YoY growth, and operating margin for direct comparisons.