Agenus Inc. (AGEN) Revenue History
Annual and quarterly revenue from 2014 to 2025
Compound Annual Growth Rate (CAGR)
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AGEN Revenue Growth
Revenue Breakdown (FY 2025)
AGEN's revenue distribution by segment and geography for fiscal year 2025
By Product/Segment
By Geography
AGEN Revenue Analysis (2014–2025)
As of May 6, 2026, Agenus Inc. (AGEN) generated trailing twelve-month (TTM) revenue of $114.2 million, reflecting exceptional growth of +27.5% year-over-year. The most recent quarter (Q4 2025) recorded $34.2 million in revenue, up 13.1% sequentially.
Looking at the longer-term picture, AGEN's 5-year compound annual growth rate (CAGR) stands at +5.3%, indicating steady revenue expansion. The company achieved its highest annual revenue of $295.7 million in 2021.
Revenue diversification analysis shows AGEN's business is primarily driven by Non Cash Royalty Revenue (99%), and Other (1%). With over half of revenue concentrated in Non Cash Royalty Revenue, the company maintains significant focus in this area while developing other growth vectors.
When compared to Healthcare sector peers including NKTR (-32.8% YoY), INCY (+21.5% YoY), and EXEL (+3.3% YoY), AGEN has underperformed the peer group in terms of revenue growth. Compare AGEN vs NKTR →
AGEN Revenue vs Peers
Revenue metrics vs comparable public companies
| Company | TTM Revenue | YoY Growth | 5Y CAGR | Op. Margin | Compare |
|---|---|---|---|---|---|
| AGENCurrent | $114M | +27.5% | +5.3% | -18.0% | |
 NKTR | $55M | -32.8% | -18.4% | -253.7% | |
 INCY | $5.1B | +21.5% | +14.0% | 26.1% | |
 EXEL | $2.3B | +3.3% | +18.6% | 37.6% | |
 RCUS | $247M | +67.4% | +25.9% | -156.3% | |
 MGNX | $150M | +0.8% | +8.9% | -48.7% |
AGEN Historical Revenue Data (2014–2025)
| Year | Revenue | YoY % | Gross Profit | Gross Margin | Op. Income | Op. Margin |
|---|---|---|---|---|---|---|
| 2025 | $114.2M | +10.4% | $103.2M | 90.3% | $-20,556,000 | -18.0% |
| 2024 | $103.5M | -33.8% | $-52,551,000 | -50.8% | $-120,475,000 | -116.4% |
| 2023 | $156.3M | +59.5% | $-81,366,000 | -52.1% | $-159,549,000 | -102.1% |
| 2022 | $98.0M | -66.8% | $-99,235,000 | -101.2% | $-179,427,000 | -183.0% |
| 2021 | $295.7M | +235.3% | $113.6M | 38.4% | $25.7M | 8.7% |
| 2020 | $88.2M | -41.2% | $-56,796,000 | -64.4% | $-117,235,000 | -133.0% |
| 2019 | $150.0M | +307.9% | $-18,291,000 | -12.2% | $-70,137,000 | -46.7% |
| 2018 | $36.8M | -14.2% | $-87,816,808 | -238.7% | $-123,821,556 | -336.6% |
| 2017 | $42.9M | +89.9% | $-73,248,000 | -170.8% | $-103,801,000 | -242.1% |
| 2016 | $22.6M | -9.0% | $-72,398,000 | -320.7% | $-107,477,000 | -476.1% |
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Start ComparisonAGEN — Frequently Asked Questions
Quick answers to the most common questions about buying AGEN stock.
Is AGEN's revenue growth accelerating or slowing?
AGEN revenue is accelerating at +27.5% year-over-year, exceeding the 5-year CAGR of +5.3%. TTM revenue reached $114M. Growth momentum has increased versus prior periods.
What is AGEN's long-term revenue growth rate?
Agenus Inc.'s 5-year revenue CAGR of +5.3% reflects the sustained expansion pattern. Current YoY growth of +27.5% is above this long-term average.
How is AGEN's revenue distributed by segment?
AGEN reports revenue by product line and geographic region. Annual and quarterly breakdowns from 2014-2025 are available for download. Segment mix reveals concentration and diversification trends.