Drug Manufacturers - Specialty & Generic
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AKAN vs DBVT vs ALKS vs TLRY
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Drug Manufacturers - Specialty & Generic
AKAN vs DBVT vs ALKS vs TLRY — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Drug Manufacturers - Specialty & Generic | Biotechnology | Biotechnology | Drug Manufacturers - Specialty & Generic |
| Market Cap | $1M | $1712.35T | $5.90B | $660M |
| Revenue (TTM) | $2M | $0.00 | $1.56B | $1.17B |
| Net Income (TTM) | $-31M | $-168M | $153M | $-2.95B |
| Gross Margin | -43.7% | — | 65.4% | 28.0% |
| Operating Margin | -6.3% | — | 12.3% | -266.0% |
| Forward P/E | — | — | 24.8x | — |
| Total Debt | $353K | $22M | $70M | $451M |
| Cash & Equiv. | $4M | $194M | $1.12B | $304M |
AKAN vs DBVT vs ALKS vs TLRY — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Mar 22 | May 26 | Return |
|---|---|---|---|
| Akanda Corp. (AKAN) | 100 | 0.0 | -100.0% |
| DBV Technologies S.… (DBVT) | 100 | 125.7 | +25.7% |
| Alkermes plc (ALKS) | 100 | 134.5 | +34.5% |
| Tilray Brands, Inc. (TLRY) | 100 | 72.8 | -27.2% |
Price return only. Dividends and distributions are not included.
Quick Verdict: AKAN vs DBVT vs ALKS vs TLRY
Each card shows where this stock fits in a portfolio — not just who wins on paper.
AKAN is the clearest fit if your priority is growth exposure.
- Rev growth -61.3%, EPS growth 100.0%, 3Y rev CAGR 172.3%
DBVT is the clearest fit if your priority is income & stability.
- Dividend streak 0 yrs, beta 1.26
ALKS carries the broadest edge in this set and is the clearest fit for long-term compounding and sleep-well-at-night.
- -11.0% 10Y total return vs TLRY's -74.7%
- Lower volatility, beta 1.06, Low D/E 3.8%, current ratio 3.55x
- Beta 1.06, current ratio 3.55x
- 9.8% margin vs AKAN's -19.6%
TLRY is the #2 pick in this set and the best alternative if growth and momentum is your priority.
- 4.8% revenue growth vs DBVT's -100.0%
- +12.1% vs AKAN's -46.1%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 4.8% revenue growth vs DBVT's -100.0% | |
| Quality / Margins | 9.8% margin vs AKAN's -19.6% | |
| Stability / Safety | Beta 1.06 vs TLRY's 2.03, lower leverage | |
| Dividends | Tie | None of these 4 stocks pay a meaningful dividend |
| Momentum (1Y) | +12.1% vs AKAN's -46.1% | |
| Efficiency (ROA) | 5.4% ROA vs AKAN's -380.2%, ROIC 18.9% vs -7.5% |
AKAN vs DBVT vs ALKS vs TLRY — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
AKAN vs DBVT vs ALKS vs TLRY — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
ALKS leads in 3 of 6 categories
TLRY leads 1 • AKAN leads 0 • DBVT leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
ALKS leads this category, winning 5 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
ALKS and DBVT operate at a comparable scale, with $1.6B and $0 in trailing revenue. ALKS is the more profitable business, keeping 9.8% of every revenue dollar as net income compared to AKAN's -19.6%. On growth, ALKS holds the edge at +28.2% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $2M | $0 | $1.6B | $1.2B |
| EBITDAEarnings before interest/tax | -$8M | -$112M | $212M | -$3.0B |
| Net IncomeAfter-tax profit | -$31M | -$168M | $153M | -$2.9B |
| Free Cash FlowCash after capex | -$7M | -$151M | $392M | -$94M |
| Gross MarginGross profit ÷ Revenue | -43.7% | — | +65.4% | +28.0% |
| Operating MarginEBIT ÷ Revenue | -6.3% | — | +12.3% | -2.7% |
| Net MarginNet income ÷ Revenue | -19.6% | — | +9.8% | -2.5% |
| FCF MarginFCF ÷ Revenue | -4.4% | — | +25.1% | -8.1% |
| Rev. Growth (YoY)Latest quarter vs prior year | -100.0% | — | +28.2% | +3.0% |
| EPS Growth (YoY)Latest quarter vs prior year | +88.4% | +91.5% | -4.1% | +70.7% |
Valuation Metrics
Evenly matched — AKAN and DBVT and TLRY each lead in 1 of 3 comparable metrics.
Valuation Metrics
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $1M | $1712.35T | $5.9B | $660M |
| Enterprise ValueMkt cap + debt − cash | -$2M | $1712.35T | $4.9B | $806M |
| Trailing P/EPrice ÷ TTM EPS | -0.14x | -0.76x | 24.76x | -0.17x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | 17.25x | — |
| Price / SalesMarket cap ÷ Revenue | 1.44x | — | 4.00x | 0.59x |
| Price / BookPrice ÷ Book value/share | 0.14x | 0.66x | 3.28x | 0.25x |
| Price / FCFMarket cap ÷ FCF | — | — | 12.28x | — |
Profitability & Efficiency
ALKS leads this category, winning 8 of 9 comparable metrics.
Profitability & Efficiency
ALKS delivers a 8.8% return on equity — every $100 of shareholder capital generates $9 in annual profit, vs $-15 for AKAN. ALKS carries lower financial leverage with a 0.04x debt-to-equity ratio, signaling a more conservative balance sheet compared to TLRY's 0.22x. On the Piotroski fundamental quality scale (0–9), ALKS scores 7/9 vs TLRY's 4/9, reflecting strong financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -15.1% | -130.2% | +8.8% | -136.5% |
| ROA (TTM)Return on assets | -3.8% | -89.0% | +5.4% | -100.6% |
| ROICReturn on invested capital | -7.5% | — | +18.9% | -66.2% |
| ROCEReturn on capital employed | -3.0% | -145.7% | +14.2% | -78.1% |
| Piotroski ScoreFundamental quality 0–9 | 5 | 4 | 7 | 4 |
| Debt / EquityFinancial leverage | 0.08x | 0.13x | 0.04x | 0.22x |
| Net DebtTotal debt minus cash | -$3M | -$172M | -$1.0B | $147M |
| Cash & Equiv.Liquid assets | $4M | $194M | $1.1B | $304M |
| Total DebtShort + long-term debt | $352,814 | $22M | $70M | $451M |
| Interest CoverageEBIT ÷ Interest expense | -47.93x | -189.82x | 32.30x | -89.43x |
Total Returns (Dividends Reinvested)
TLRY leads this category, winning 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ALKS five years ago would be worth $16,091 today (with dividends reinvested), compared to $1 for AKAN. Over the past 12 months, TLRY leads with a +1209.3% total return vs AKAN's -46.1%. The 3-year compound annual growth rate (CAGR) favors TLRY at 26.7% vs AKAN's -80.5% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | +277.9% | +4.9% | +25.3% | -41.8% |
| 1-Year ReturnPast 12 months | -46.1% | +110.4% | +16.5% | +1209.3% |
| 3-Year ReturnCumulative with dividends | -99.3% | +19.7% | +14.5% | +103.6% |
| 5-Year ReturnCumulative with dividends | -100.0% | -69.1% | +60.9% | -65.0% |
| 10-Year ReturnCumulative with dividends | -100.0% | -87.0% | -11.0% | -74.7% |
| CAGR (3Y)Annualised 3-year return | -80.5% | +6.2% | +4.6% | +26.7% |
Risk & Volatility
ALKS leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
ALKS is the less volatile stock with a 1.06 beta — it tends to amplify market swings less than TLRY's 2.03 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ALKS currently trades 96.7% from its 52-week high vs AKAN's 20.0% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.71x | 1.26x | 1.06x | 2.03x |
| 52-Week HighHighest price in past year | $185.80 | $26.18 | $36.60 | $15.70 |
| 52-Week LowLowest price in past year | $1.41 | $7.53 | $25.17 | $0.35 |
| % of 52W HighCurrent price vs 52-week peak | +20.0% | +76.3% | +96.7% | +36.1% |
| RSI (14)Momentum oscillator 0–100 | 61.0 | 48.1 | 60.2 | 37.9 |
| Avg Volume (50D)Average daily shares traded | 2.7M | 252K | 2.3M | 4.7M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: DBVT as "Buy", ALKS as "Buy", TLRY as "Hold". Consensus price targets imply 131.8% upside for DBVT (target: $46) vs 24.3% for ALKS (target: $44).
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | Buy | Hold |
| Price TargetConsensus 12-month target | — | $46.33 | $44.00 | $10.00 |
| # AnalystsCovering analysts | — | 15 | 28 | 20 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | 0 | 0 | — |
| Dividend / ShareAnnual DPS | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | +0.5% | 0.0% |
ALKS leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). TLRY leads in 1 (Total Returns). 1 tied.
AKAN vs DBVT vs ALKS vs TLRY: Key Questions Answered
8 questions · data-driven answers · updated daily
01Is AKAN or DBVT or ALKS or TLRY a better buy right now?
For growth investors, Tilray Brands, Inc.
(TLRY) is the stronger pick with 4. 8% revenue growth year-over-year, versus -61. 3% for Akanda Corp. (AKAN). Alkermes plc (ALKS) offers the better valuation at 24. 8x trailing P/E, making it the more compelling value choice. Analysts rate DBV Technologies S. A. (DBVT) a "Buy" — based on 15 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — AKAN or DBVT or ALKS or TLRY?
Over the past 5 years, Alkermes plc (ALKS) delivered a total return of +60.
9%, compared to -100. 0% for Akanda Corp. (AKAN). Over 10 years, the gap is even starker: ALKS returned -11. 0% versus AKAN's -100. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — AKAN or DBVT or ALKS or TLRY?
By beta (market sensitivity over 5 years), Alkermes plc (ALKS) is the lower-risk stock at 1.
06β versus Tilray Brands, Inc. 's 2. 03β — meaning TLRY is approximately 91% more volatile than ALKS relative to the S&P 500. On balance sheet safety, Alkermes plc (ALKS) carries a lower debt/equity ratio of 4% versus 22% for Tilray Brands, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — AKAN or DBVT or ALKS or TLRY?
By revenue growth (latest reported year), Tilray Brands, Inc.
(TLRY) is pulling ahead at 4. 8% versus -61. 3% for Akanda Corp. (AKAN). On earnings-per-share growth, the picture is similar: Akanda Corp. grew EPS 100. 0% year-over-year, compared to -651. 7% for Tilray Brands, Inc.. Over a 3-year CAGR, AKAN leads at 172. 3% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — AKAN or DBVT or ALKS or TLRY?
Alkermes plc (ALKS) is the more profitable company, earning 16.
4% net margin versus -489. 6% for Akanda Corp. — meaning it keeps 16. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ALKS leads at 17. 2% versus -523. 8% for AKAN. At the gross margin level — before operating expenses — ALKS leads at 86. 7%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — AKAN or DBVT or ALKS or TLRY?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is AKAN or DBVT or ALKS or TLRY better for a retirement portfolio?
For long-horizon retirement investors, Alkermes plc (ALKS) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1.
06)). Tilray Brands, Inc. (TLRY) carries a higher beta of 2. 03 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ALKS: -11. 0%, TLRY: -74. 7%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between AKAN and DBVT and ALKS and TLRY?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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