Medical - Instruments & Supplies
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ANGO vs CNMD vs HOLX vs NVCR
Revenue, margins, valuation, and 5-year total return — side by side.
Medical - Devices
Medical - Instruments & Supplies
Medical - Instruments & Supplies
ANGO vs CNMD vs HOLX vs NVCR — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Medical - Instruments & Supplies | Medical - Devices | Medical - Instruments & Supplies | Medical - Instruments & Supplies |
| Market Cap | $469M | $1.17B | $16.97B | $1.92B |
| Revenue (TTM) | $307M | $1.37B | $4.13B | $674M |
| Net Income (TTM) | $-28M | $55M | $544M | $-173M |
| Gross Margin | 53.7% | 53.6% | 52.8% | 75.2% |
| Operating Margin | -9.4% | 11.3% | 17.5% | -27.2% |
| Forward P/E | — | 8.7x | 17.2x | — |
| Total Debt | $0.00 | $835M | $2.63B | $290M |
| Cash & Equiv. | $56M | $41M | $1.96B | $103M |
ANGO vs CNMD vs HOLX vs NVCR — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| AngioDynamics, Inc. (ANGO) | 100 | 110.4 | +10.4% |
| CONMED Corporation (CNMD) | 100 | 51.9 | -48.1% |
| Hologic, Inc. (HOLX) | 100 | 142.6 | +42.6% |
| NovoCure Limited (NVCR) | 100 | 25.0 | -75.0% |
Price return only. Dividends and distributions are not included.
Quick Verdict: ANGO vs CNMD vs HOLX vs NVCR
Each card shows where this stock fits in a portfolio — not just who wins on paper.
ANGO lags the leaders in this set but could rank higher in a more targeted comparison.
CNMD is the #2 pick in this set and the best alternative if value and dividends is your priority.
- Better valuation composite
- 2.1% yield; 2-year raise streak; the other 3 pay no meaningful dividend
HOLX carries the broadest edge in this set and is the clearest fit for income & stability and long-term compounding.
- beta 0.41
- 124.3% 10Y total return vs NVCR's 30.3%
- Lower volatility, beta 0.41, Low D/E 52.0%, current ratio 3.75x
- Beta 0.41, current ratio 3.75x
NVCR is the clearest fit if your priority is growth exposure.
- Rev growth 8.3%, EPS growth 21.8%, 3Y rev CAGR 6.8%
- 8.3% revenue growth vs ANGO's -3.8%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 8.3% revenue growth vs ANGO's -3.8% | |
| Value | Better valuation composite | |
| Quality / Margins | 13.2% margin vs NVCR's -25.7% | |
| Stability / Safety | Beta 0.41 vs NVCR's 2.20, lower leverage | |
| Dividends | 2.1% yield; 2-year raise streak; the other 3 pay no meaningful dividend | |
| Momentum (1Y) | +37.1% vs CNMD's -31.3% | |
| Efficiency (ROA) | 6.1% ROA vs NVCR's -16.5%, ROIC 9.4% vs -16.4% |
ANGO vs CNMD vs HOLX vs NVCR — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
ANGO vs CNMD vs HOLX vs NVCR — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
HOLX leads in 4 of 6 categories
CNMD leads 1 • ANGO leads 0 • NVCR leads 0
Explore the data ↓Income & Cash Flow (Last 12 Months)
HOLX leads this category, winning 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
HOLX is the larger business by revenue, generating $4.1B annually — 13.4x ANGO's $307M. HOLX is the more profitable business, keeping 13.2% of every revenue dollar as net income compared to NVCR's -25.7%. On growth, NVCR holds the edge at +12.3% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $307M | $1.4B | $4.1B | $674M |
| EBITDAEarnings before interest/tax | -$5M | $219M | $974M | -$165M |
| Net IncomeAfter-tax profit | -$28M | $55M | $544M | -$173M |
| Free Cash FlowCash after capex | -$9M | $124M | $1000M | -$48M |
| Gross MarginGross profit ÷ Revenue | +53.7% | +53.6% | +52.8% | +75.2% |
| Operating MarginEBIT ÷ Revenue | -9.4% | +11.3% | +17.5% | -27.2% |
| Net MarginNet income ÷ Revenue | -9.0% | +4.0% | +13.2% | -25.7% |
| FCF MarginFCF ÷ Revenue | -3.0% | +9.0% | +24.2% | -7.1% |
| Rev. Growth (YoY)Latest quarter vs prior year | +9.0% | -0.7% | +2.5% | +12.3% |
| EPS Growth (YoY)Latest quarter vs prior year | +42.3% | +136.8% | -9.2% | -100.0% |
Valuation Metrics
CNMD leads this category, winning 5 of 6 comparable metrics.
Valuation Metrics
At 25.2x trailing earnings, CNMD trades at a 17% valuation discount to HOLX's 30.5x P/E. On an enterprise value basis, CNMD's 10.2x EV/EBITDA is more attractive than HOLX's 17.4x.
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $469M | $1.2B | $17.0B | $1.9B |
| Enterprise ValueMkt cap + debt − cash | $413M | $2.0B | $17.6B | $2.1B |
| Trailing P/EPrice ÷ TTM EPS | -13.58x | 25.22x | 30.53x | -13.80x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 8.71x | 17.21x | — |
| PEG RatioP/E ÷ EPS growth rate | — | 0.69x | — | — |
| EV / EBITDAEnterprise value multiple | — | 10.17x | 17.39x | — |
| Price / SalesMarket cap ÷ Revenue | 1.60x | 0.85x | 4.14x | 2.92x |
| Price / BookPrice ÷ Book value/share | 2.52x | 1.15x | 3.43x | 5.51x |
| Price / FCFMarket cap ÷ FCF | — | 7.78x | 18.44x | — |
Profitability & Efficiency
HOLX leads this category, winning 7 of 9 comparable metrics.
Profitability & Efficiency
HOLX delivers a 11.0% return on equity — every $100 of shareholder capital generates $11 in annual profit, vs $-51 for NVCR. HOLX carries lower financial leverage with a 0.52x debt-to-equity ratio, signaling a more conservative balance sheet compared to NVCR's 0.85x. On the Piotroski fundamental quality scale (0–9), HOLX scores 7/9 vs NVCR's 5/9, reflecting strong financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -15.7% | +5.4% | +11.0% | -50.8% |
| ROA (TTM)Return on assets | -10.3% | +2.4% | +6.1% | -16.5% |
| ROICReturn on invested capital | -22.9% | +5.8% | +9.4% | -16.4% |
| ROCEReturn on capital employed | -18.6% | +7.0% | +8.8% | -28.9% |
| Piotroski ScoreFundamental quality 0–9 | 5 | 5 | 7 | 5 |
| Debt / EquityFinancial leverage | — | 0.81x | 0.52x | 0.85x |
| Net DebtTotal debt minus cash | -$56M | $794M | $667M | $187M |
| Cash & Equiv.Liquid assets | $56M | $41M | $2.0B | $103M |
| Total DebtShort + long-term debt | $0 | $835M | $2.6B | $290M |
| Interest CoverageEBIT ÷ Interest expense | -258.19x | 5.20x | 8.00x | -96.80x |
Total Returns (Dividends Reinvested)
HOLX leads this category, winning 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in HOLX five years ago would be worth $11,582 today (with dividends reinvested), compared to $875 for NVCR. Over the past 12 months, HOLX leads with a +37.1% total return vs CNMD's -31.3%. The 3-year compound annual growth rate (CAGR) favors ANGO at 7.9% vs NVCR's -37.6% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | -11.1% | -6.0% | +1.9% | +28.3% |
| 1-Year ReturnPast 12 months | +28.5% | -31.3% | +37.1% | +1.1% |
| 3-Year ReturnCumulative with dividends | +25.8% | -67.3% | -8.5% | -75.7% |
| 5-Year ReturnCumulative with dividends | -53.3% | -71.0% | +15.8% | -91.3% |
| 10-Year ReturnCumulative with dividends | -9.2% | +6.6% | +124.3% | +30.3% |
| CAGR (3Y)Annualised 3-year return | +7.9% | -31.1% | -2.9% | -37.6% |
Risk & Volatility
HOLX leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
HOLX is the less volatile stock with a 0.41 beta — it tends to amplify market swings less than NVCR's 2.20 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. HOLX currently trades 100.0% from its 52-week high vs CNMD's 62.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.32x | 1.34x | 0.41x | 2.20x |
| 52-Week HighHighest price in past year | $13.99 | $61.08 | $76.04 | $20.06 |
| 52-Week LowLowest price in past year | $8.36 | $33.21 | $52.81 | $9.82 |
| % of 52W HighCurrent price vs 52-week peak | +80.6% | +62.4% | +100.0% | +83.9% |
| RSI (14)Momentum oscillator 0–100 | 54.0 | 49.6 | 69.1 | 69.8 |
| Avg Volume (50D)Average daily shares traded | 395K | 406K | 10.0M | 1.5M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: ANGO as "Hold", CNMD as "Hold", HOLX as "Hold", NVCR as "Buy". Consensus price targets imply 104.8% upside for CNMD (target: $78) vs 3.9% for HOLX (target: $79). CNMD is the only dividend payer here at 2.09% yield — a key consideration for income-focused portfolios.
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Hold | Hold | Hold | Buy |
| Price TargetConsensus 12-month target | $16.50 | $78.00 | $79.00 | $33.50 |
| # AnalystsCovering analysts | 11 | 21 | 42 | 15 |
| Dividend YieldAnnual dividend ÷ price | — | +2.1% | — | — |
| Dividend StreakConsecutive years of raises | — | 2 | — | — |
| Dividend / ShareAnnual DPS | — | $0.79 | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | +0.4% | 0.0% | +4.4% | 0.0% |
HOLX leads in 4 of 6 categories (Income & Cash Flow, Profitability & Efficiency). CNMD leads in 1 (Valuation Metrics).
ANGO vs CNMD vs HOLX vs NVCR: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is ANGO or CNMD or HOLX or NVCR a better buy right now?
For growth investors, NovoCure Limited (NVCR) is the stronger pick with 8.
3% revenue growth year-over-year, versus -3. 8% for AngioDynamics, Inc. (ANGO). CONMED Corporation (CNMD) offers the better valuation at 25. 2x trailing P/E (8. 7x forward), making it the more compelling value choice. Analysts rate NovoCure Limited (NVCR) a "Buy" — based on 15 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — ANGO or CNMD or HOLX or NVCR?
On trailing P/E, CONMED Corporation (CNMD) is the cheapest at 25.
2x versus Hologic, Inc. at 30. 5x. On forward P/E, CONMED Corporation is actually cheaper at 8. 7x.
03Which is the better long-term investment — ANGO or CNMD or HOLX or NVCR?
Over the past 5 years, Hologic, Inc.
(HOLX) delivered a total return of +15. 8%, compared to -91. 3% for NovoCure Limited (NVCR). Over 10 years, the gap is even starker: HOLX returned +124. 3% versus ANGO's -9. 2%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — ANGO or CNMD or HOLX or NVCR?
By beta (market sensitivity over 5 years), Hologic, Inc.
(HOLX) is the lower-risk stock at 0. 41β versus NovoCure Limited's 2. 20β — meaning NVCR is approximately 437% more volatile than HOLX relative to the S&P 500. On balance sheet safety, Hologic, Inc. (HOLX) carries a lower debt/equity ratio of 52% versus 85% for NovoCure Limited — giving it more financial flexibility in a downturn.
05Which is growing faster — ANGO or CNMD or HOLX or NVCR?
By revenue growth (latest reported year), NovoCure Limited (NVCR) is pulling ahead at 8.
3% versus -3. 8% for AngioDynamics, Inc. (ANGO). On earnings-per-share growth, the picture is similar: AngioDynamics, Inc. grew EPS 81. 9% year-over-year, compared to -64. 6% for CONMED Corporation. Over a 3-year CAGR, CNMD leads at 9. 5% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — ANGO or CNMD or HOLX or NVCR?
Hologic, Inc.
(HOLX) is the more profitable company, earning 13. 8% net margin versus -20. 8% for NovoCure Limited — meaning it keeps 13. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: HOLX leads at 17. 4% versus -23. 5% for NVCR. At the gross margin level — before operating expenses — NVCR leads at 74. 5%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is ANGO or CNMD or HOLX or NVCR more undervalued right now?
On forward earnings alone, CONMED Corporation (CNMD) trades at 8.
7x forward P/E versus 17. 2x for Hologic, Inc. — 8. 5x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for CNMD: 104. 8% to $78. 00.
08Which pays a better dividend — ANGO or CNMD or HOLX or NVCR?
In this comparison, CNMD (2.
1% yield) pays a dividend. ANGO, HOLX, NVCR do not pay a meaningful dividend and should not be held primarily for income.
09Is ANGO or CNMD or HOLX or NVCR better for a retirement portfolio?
For long-horizon retirement investors, Hologic, Inc.
(HOLX) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 41), +124. 3% 10Y return). NovoCure Limited (NVCR) carries a higher beta of 2. 20 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (HOLX: +124. 3%, NVCR: +30. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between ANGO and CNMD and HOLX and NVCR?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
CNMD pays a dividend while ANGO, HOLX, NVCR do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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