Medical - Devices
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4 / 10Stock Comparison
AXGN vs MDXG vs TELA vs NVCR
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Medical - Devices
Medical - Instruments & Supplies
AXGN vs MDXG vs TELA vs NVCR — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Medical - Devices | Biotechnology | Medical - Devices | Medical - Instruments & Supplies |
| Market Cap | $2.24B | $548M | $44M | $1.92B |
| Revenue (TTM) | $238M | $389M | $77M | $674M |
| Net Income (TTM) | $-31M | $31M | $-39M | $-173M |
| Gross Margin | 75.0% | 81.0% | 67.2% | 75.2% |
| Operating Margin | -3.8% | 10.2% | -46.0% | -27.2% |
| Forward P/E | 86.5x | 295.2x | — | — |
| Total Debt | $19M | $23M | $43M | $290M |
| Cash & Equiv. | $36M | $166M | $53M | $103M |
AXGN vs MDXG vs TELA vs NVCR — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| AxoGen, Inc. (AXGN) | 100 | 433.6 | +333.6% |
| MiMedx Group, Inc. (MDXG) | 100 | 100.3 | +0.3% |
| TELA Bio, Inc. (TELA) | 100 | 7.4 | -92.6% |
| NovoCure Limited (NVCR) | 100 | 26.5 | -73.5% |
Price return only. Dividends and distributions are not included.
Quick Verdict: AXGN vs MDXG vs TELA vs NVCR
Each card shows where this stock fits in a portfolio — not just who wins on paper.
AXGN carries the broadest edge in this set and is the clearest fit for long-term compounding and sleep-well-at-night.
- 6.5% 10Y total return vs NVCR's 30.3%
- Lower volatility, beta 0.90, Low D/E 14.9%, current ratio 5.11x
- 20.2% revenue growth vs NVCR's 8.3%
- Better valuation composite
MDXG is the #2 pick in this set and the best alternative if quality and efficiency is your priority.
- 7.9% margin vs TELA's -50.6%
- 9.7% ROA vs TELA's -53.1%, ROIC 42.3% vs -151.6%
TELA is the clearest fit if your priority is income & stability and growth exposure.
- beta 0.57
- Rev growth 18.6%, EPS growth 34.8%, 3Y rev CAGR 33.0%
- Beta 0.57, current ratio 5.01x
- Beta 0.57 vs NVCR's 2.20
NVCR lags the leaders in this set but could rank higher in a more targeted comparison.
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 20.2% revenue growth vs NVCR's 8.3% | |
| Value | Better valuation composite | |
| Quality / Margins | 7.9% margin vs TELA's -50.6% | |
| Stability / Safety | Beta 0.57 vs NVCR's 2.20 | |
| Dividends | Tie | None of these 4 stocks pay a meaningful dividend |
| Momentum (1Y) | +164.9% vs MDXG's -47.1% | |
| Efficiency (ROA) | 9.7% ROA vs TELA's -53.1%, ROIC 42.3% vs -151.6% |
AXGN vs MDXG vs TELA vs NVCR — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
Segment breakdown not available.
AXGN vs MDXG vs TELA vs NVCR — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
MDXG leads in 2 of 6 categories
AXGN leads 1 • TELA leads 0 • NVCR leads 0 • 2 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
MDXG leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
NVCR is the larger business by revenue, generating $674M annually — 8.8x TELA's $77M. MDXG is the more profitable business, keeping 7.9% of every revenue dollar as net income compared to TELA's -50.6%. On growth, AXGN holds the edge at +26.6% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $238M | $389M | $77M | $674M |
| EBITDAEarnings before interest/tax | -$3M | $53M | -$34M | -$165M |
| Net IncomeAfter-tax profit | -$31M | $31M | -$39M | -$173M |
| Free Cash FlowCash after capex | $9M | $66M | -$32M | -$48M |
| Gross MarginGross profit ÷ Revenue | +75.0% | +81.0% | +67.2% | +75.2% |
| Operating MarginEBIT ÷ Revenue | -3.8% | +10.2% | -46.0% | -27.2% |
| Net MarginNet income ÷ Revenue | -13.2% | +7.9% | -50.6% | -25.7% |
| FCF MarginFCF ÷ Revenue | +3.8% | +17.0% | -40.9% | -7.1% |
| Rev. Growth (YoY)Latest quarter vs prior year | +26.6% | -33.1% | +9.1% | +12.3% |
| EPS Growth (YoY)Latest quarter vs prior year | -3.5% | -2.4% | +54.8% | -100.0% |
Valuation Metrics
Evenly matched — AXGN and TELA each lead in 2 of 5 comparable metrics.
Valuation Metrics
On an enterprise value basis, MDXG's 5.1x EV/EBITDA is more attractive than AXGN's 6463.0x.
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $2.2B | $548M | $44M | $1.9B |
| Enterprise ValueMkt cap + debt − cash | $2.2B | $405M | $35M | $2.1B |
| Trailing P/EPrice ÷ TTM EPS | -127.68x | 11.53x | -0.83x | -13.80x |
| Forward P/EPrice ÷ next-FY EPS est. | 86.49x | 295.20x | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — |
| EV / EBITDAEnterprise value multiple | 6463.03x | 5.14x | — | — |
| Price / SalesMarket cap ÷ Revenue | 9.94x | 1.31x | 0.64x | 2.92x |
| Price / BookPrice ÷ Book value/share | 15.51x | 2.15x | 1.10x | 5.51x |
| Price / FCFMarket cap ÷ FCF | — | 7.51x | — | — |
Profitability & Efficiency
MDXG leads this category, winning 8 of 9 comparable metrics.
Profitability & Efficiency
MDXG delivers a 12.9% return on equity — every $100 of shareholder capital generates $13 in annual profit, vs $-3 for TELA. MDXG carries lower financial leverage with a 0.09x debt-to-equity ratio, signaling a more conservative balance sheet compared to TELA's 1.51x. On the Piotroski fundamental quality scale (0–9), AXGN scores 5/9 vs TELA's 4/9, reflecting solid financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -20.7% | +12.9% | -2.7% | -50.8% |
| ROA (TTM)Return on assets | -13.5% | +9.7% | -53.1% | -16.5% |
| ROICReturn on invested capital | -4.6% | +42.3% | -151.6% | -16.4% |
| ROCEReturn on capital employed | -4.2% | +25.7% | -51.4% | -28.9% |
| Piotroski ScoreFundamental quality 0–9 | 5 | 5 | 4 | 5 |
| Debt / EquityFinancial leverage | 0.15x | 0.09x | 1.51x | 0.85x |
| Net DebtTotal debt minus cash | -$16M | -$144M | -$10M | $187M |
| Cash & Equiv.Liquid assets | $36M | $166M | $53M | $103M |
| Total DebtShort + long-term debt | $19M | $23M | $43M | $290M |
| Interest CoverageEBIT ÷ Interest expense | -0.05x | 25.32x | -6.99x | -96.80x |
Total Returns (Dividends Reinvested)
AXGN leads this category, winning 6 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in AXGN five years ago would be worth $18,472 today (with dividends reinvested), compared to $853 for TELA. Over the past 12 months, AXGN leads with a +164.9% total return vs MDXG's -47.1%. The 3-year compound annual growth rate (CAGR) favors AXGN at 65.0% vs TELA's -51.9% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | +40.0% | -43.1% | -3.5% | +28.3% |
| 1-Year ReturnPast 12 months | +164.9% | -47.1% | +15.8% | +1.1% |
| 3-Year ReturnCumulative with dividends | +349.4% | -36.6% | -88.9% | -75.7% |
| 5-Year ReturnCumulative with dividends | +84.7% | -62.9% | -91.5% | -91.3% |
| 10-Year ReturnCumulative with dividends | +647.2% | -48.5% | -91.8% | +30.3% |
| CAGR (3Y)Annualised 3-year return | +65.0% | -14.1% | -51.9% | -37.6% |
Risk & Volatility
Evenly matched — AXGN and TELA each lead in 1 of 2 comparable metrics.
Risk & Volatility
TELA is the less volatile stock with a 0.57 beta — it tends to amplify market swings less than NVCR's 2.20 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. AXGN currently trades 94.9% from its 52-week high vs MDXG's 46.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.93x | 1.21x | 0.33x | 2.15x |
| 52-Week HighHighest price in past year | $45.75 | $7.99 | $2.20 | $20.06 |
| 52-Week LowLowest price in past year | $9.22 | $3.02 | $0.50 | $9.82 |
| % of 52W HighCurrent price vs 52-week peak | +94.9% | +46.2% | +50.0% | +83.9% |
| RSI (14)Momentum oscillator 0–100 | 70.4 | 49.3 | 62.7 | 69.8 |
| Avg Volume (50D)Average daily shares traded | 968K | 1.4M | 188K | 1.5M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: AXGN as "Buy", MDXG as "Buy", NVCR as "Buy". Consensus price targets imply 171.0% upside for MDXG (target: $10) vs 0.0% for AXGN (target: $43).
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | — | Buy |
| Price TargetConsensus 12-month target | $43.43 | $10.00 | — | $33.50 |
| # AnalystsCovering analysts | 19 | 15 | — | 15 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — |
| Dividend StreakConsecutive years of raises | 2 | — | — | — |
| Dividend / ShareAnnual DPS | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +0.6% | 0.0% | 0.0% |
MDXG leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). AXGN leads in 1 (Total Returns). 2 tied.
AXGN vs MDXG vs TELA vs NVCR: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is AXGN or MDXG or TELA or NVCR a better buy right now?
For growth investors, AxoGen, Inc.
(AXGN) is the stronger pick with 20. 2% revenue growth year-over-year, versus 8. 3% for NovoCure Limited (NVCR). MiMedx Group, Inc. (MDXG) offers the better valuation at 11. 5x trailing P/E (295. 2x forward), making it the more compelling value choice. Analysts rate AxoGen, Inc. (AXGN) a "Buy" — based on 19 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — AXGN or MDXG or TELA or NVCR?
On forward P/E, AxoGen, Inc.
is actually cheaper at 86. 5x — notably different from the trailing picture, reflecting expected earnings growth.
03Which is the better long-term investment — AXGN or MDXG or TELA or NVCR?
Over the past 5 years, AxoGen, Inc.
(AXGN) delivered a total return of +84. 7%, compared to -91. 5% for TELA Bio, Inc. (TELA). Over 10 years, the gap is even starker: AXGN returned +623. 9% versus TELA's -92. 4%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — AXGN or MDXG or TELA or NVCR?
By beta (market sensitivity over 5 years), TELA Bio, Inc.
(TELA) is the lower-risk stock at 0. 33β versus NovoCure Limited's 2. 15β — meaning NVCR is approximately 548% more volatile than TELA relative to the S&P 500. On balance sheet safety, MiMedx Group, Inc. (MDXG) carries a lower debt/equity ratio of 9% versus 151% for TELA Bio, Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — AXGN or MDXG or TELA or NVCR?
By revenue growth (latest reported year), AxoGen, Inc.
(AXGN) is pulling ahead at 20. 2% versus 8. 3% for NovoCure Limited (NVCR). On earnings-per-share growth, the picture is similar: TELA Bio, Inc. grew EPS 34. 8% year-over-year, compared to -47. 8% for AxoGen, Inc.. Over a 3-year CAGR, TELA leads at 33. 0% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — AXGN or MDXG or TELA or NVCR?
MiMedx Group, Inc.
(MDXG) is the more profitable company, earning 11. 6% net margin versus -54. 6% for TELA Bio, Inc. — meaning it keeps 11. 6% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: MDXG leads at 15. 3% versus -49. 2% for TELA. At the gross margin level — before operating expenses — MDXG leads at 82. 6%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is AXGN or MDXG or TELA or NVCR more undervalued right now?
On forward earnings alone, AxoGen, Inc.
(AXGN) trades at 86. 5x forward P/E versus 295. 2x for MiMedx Group, Inc. — 208. 7x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for MDXG: 171. 0% to $10. 00.
08Which pays a better dividend — AXGN or MDXG or TELA or NVCR?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
09Is AXGN or MDXG or TELA or NVCR better for a retirement portfolio?
For long-horizon retirement investors, TELA Bio, Inc.
(TELA) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 33)). NovoCure Limited (NVCR) carries a higher beta of 2. 15 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (TELA: -92. 4%, NVCR: +38. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between AXGN and MDXG and TELA and NVCR?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: AXGN is a small-cap high-growth stock; MDXG is a small-cap high-growth stock; TELA is a small-cap high-growth stock; NVCR is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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