Biotechnology
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5 / 10Stock Comparison
BCAB vs ABBV vs MRK vs BMY vs REGN
Revenue, margins, valuation, and 5-year total return — side by side.
Drug Manufacturers - General
Drug Manufacturers - General
Drug Manufacturers - General
Biotechnology
BCAB vs ABBV vs MRK vs BMY vs REGN — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Drug Manufacturers - General | Drug Manufacturers - General | Drug Manufacturers - General | Biotechnology |
| Market Cap | $5M | $358.42B | $277.34B | $114.85B | $73.68B |
| Revenue (TTM) | $2M | $61.16B | $64.93B | $48.48B | $14.92B |
| Net Income (TTM) | $-60M | $4.23B | $18.25B | $7.28B | $4.42B |
| Gross Margin | 100.0% | 70.2% | 74.2% | 68.7% | 84.5% |
| Operating Margin | -29.7% | 26.7% | 41.1% | 25.7% | 24.3% |
| Forward P/E | — | 14.3x | 21.9x | 8.9x | 15.3x |
| Total Debt | $6M | $69.07B | $50.53B | $47.14B | $2.71B |
| Cash & Equiv. | $7M | $5.23B | $14.56B | $10.21B | $3.12B |
BCAB vs ABBV vs MRK vs BMY vs REGN — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Dec 20 | May 26 | Return |
|---|---|---|---|
| BioAtla, Inc. (BCAB) | 100 | 0.3 | -99.7% |
| AbbVie Inc. (ABBV) | 100 | 189.1 | +89.1% |
| Merck & Co., Inc. (MRK) | 100 | 144.0 | +44.0% |
| Bristol-Myers Squib… (BMY) | 100 | 90.7 | -9.3% |
| Regeneron Pharmaceu… (REGN) | 100 | 146.8 | +46.8% |
Price return only. Dividends and distributions are not included.
Quick Verdict: BCAB vs ABBV vs MRK vs BMY vs REGN
Each card shows where this stock fits in a portfolio — not just who wins on paper.
Among these 5 stocks, BCAB doesn't own a clear edge in any measured category.
ABBV has the current edge in this matchup, primarily because of its strength in income & stability and long-term compounding.
- Dividend streak 13 yrs, beta 0.34, yield 3.2%
- 295.5% 10Y total return vs MRK's 166.5%
- Beta 0.34, yield 3.2%, current ratio 0.67x
- 8.6% revenue growth vs BCAB's -81.8%
MRK is the #2 pick in this set and the best alternative if sleep-well-at-night and valuation efficiency is your priority.
- Lower volatility, beta 0.48, Low D/E 96.0%, current ratio 1.54x
- PEG 1.03 vs REGN's 2.43
- +46.1% vs BCAB's -80.6%
- 14.6% ROA vs BCAB's -250.6%
BMY ranks third and is worth considering specifically for value and dividends.
- Lower P/E (8.9x vs 15.3x)
- 4.4% yield, 6-year raise streak, vs MRK's 2.9%, (1 stock pays no dividend)
REGN is the clearest fit if your priority is growth exposure.
- Rev growth 1.0%, EPS growth 8.2%, 3Y rev CAGR 5.6%
- 29.6% margin vs BCAB's -29.8%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 8.6% revenue growth vs BCAB's -81.8% | |
| Value | Lower P/E (8.9x vs 15.3x) | |
| Quality / Margins | 29.6% margin vs BCAB's -29.8% | |
| Stability / Safety | Beta 0.34 vs REGN's 0.81 | |
| Dividends | 4.4% yield, 6-year raise streak, vs MRK's 2.9%, (1 stock pays no dividend) | |
| Momentum (1Y) | +46.1% vs BCAB's -80.6% | |
| Efficiency (ROA) | 14.6% ROA vs BCAB's -250.6% |
BCAB vs ABBV vs MRK vs BMY vs REGN — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
BCAB vs ABBV vs MRK vs BMY vs REGN — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
BMY leads in 1 of 6 categories
REGN leads 1 • ABBV leads 1 • BCAB leads 0 • MRK leads 0 • 3 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
Evenly matched — ABBV and REGN each lead in 2 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
MRK is the larger business by revenue, generating $64.9B annually — 32463.0x BCAB's $2M. REGN is the more profitable business, keeping 29.6% of every revenue dollar as net income compared to BCAB's -29.8%. On growth, REGN holds the edge at +19.0% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $2M | $61.2B | $64.9B | $48.5B | $14.9B |
| EBITDAEarnings before interest/tax | -$59M | $24.5B | $32.4B | $15.7B | $4.2B |
| Net IncomeAfter-tax profit | -$60M | $4.2B | $18.3B | $7.3B | $4.4B |
| Free Cash FlowCash after capex | -$34M | $18.7B | $12.4B | $11.9B | $4.2B |
| Gross MarginGross profit ÷ Revenue | +100.0% | +70.2% | +74.2% | +68.7% | +84.5% |
| Operating MarginEBIT ÷ Revenue | -29.7% | +26.7% | +41.1% | +25.7% | +24.3% |
| Net MarginNet income ÷ Revenue | -29.8% | +6.9% | +28.1% | +15.0% | +29.6% |
| FCF MarginFCF ÷ Revenue | -17.0% | +30.6% | +19.0% | +24.6% | +27.9% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | +10.0% | +4.5% | +2.6% | +19.0% |
| EPS Growth (YoY)Latest quarter vs prior year | +46.7% | +57.4% | -19.6% | +9.2% | -7.2% |
Valuation Metrics
BMY leads this category, winning 4 of 7 comparable metrics.
Valuation Metrics
At 15.4x trailing earnings, MRK trades at a 82% valuation discount to ABBV's 85.5x P/E. Adjusting for growth (PEG ratio), MRK offers better value at 0.73x vs REGN's 2.70x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $5M | $358.4B | $277.3B | $114.8B | $73.7B |
| Enterprise ValueMkt cap + debt − cash | $4M | $422.3B | $313.3B | $151.8B | $73.3B |
| Trailing P/EPrice ÷ TTM EPS | -0.09x | 85.50x | 15.42x | 16.30x | 17.09x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 14.28x | 21.93x | 8.93x | 15.35x |
| PEG RatioP/E ÷ EPS growth rate | — | — | 0.73x | — | 2.70x |
| EV / EBITDAEnterprise value multiple | — | 14.96x | 10.68x | 9.17x | 17.78x |
| Price / SalesMarket cap ÷ Revenue | 2.56x | 5.86x | 4.27x | 2.38x | 5.14x |
| Price / BookPrice ÷ Book value/share | — | — | 5.35x | 6.20x | 2.46x |
| Price / FCFMarket cap ÷ FCF | — | 20.12x | 22.44x | 8.94x | 18.06x |
Profitability & Efficiency
REGN leads this category, winning 3 of 9 comparable metrics.
Profitability & Efficiency
ABBV delivers a 62.1% return on equity — every $100 of shareholder capital generates $62 in annual profit, vs $14 for REGN. REGN carries lower financial leverage with a 0.09x debt-to-equity ratio, signaling a more conservative balance sheet compared to BMY's 2.55x. On the Piotroski fundamental quality scale (0–9), BMY scores 8/9 vs BCAB's 2/9, reflecting strong financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | — | +62.1% | +36.1% | +39.0% | +14.3% |
| ROA (TTM)Return on assets | -2.5% | +3.1% | +14.6% | +7.9% | +11.1% |
| ROICReturn on invested capital | — | +23.9% | +22.0% | +16.9% | +8.9% |
| ROCEReturn on capital employed | -4.0% | +21.5% | +23.8% | +18.7% | +10.2% |
| Piotroski ScoreFundamental quality 0–9 | 2 | 6 | 4 | 8 | 5 |
| Debt / EquityFinancial leverage | — | — | 0.96x | 2.55x | 0.09x |
| Net DebtTotal debt minus cash | -$918,000 | $63.8B | $36.0B | $36.9B | -$412M |
| Cash & Equiv.Liquid assets | $7M | $5.2B | $14.6B | $10.2B | $3.1B |
| Total DebtShort + long-term debt | $6M | $69.1B | $50.5B | $47.1B | $2.7B |
| Interest CoverageEBIT ÷ Interest expense | — | 3.28x | 19.68x | 10.33x | 108.44x |
Total Returns (Dividends Reinvested)
ABBV leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ABBV five years ago would be worth $20,131 today (with dividends reinvested), compared to $19 for BCAB. Over the past 12 months, MRK leads with a +46.1% total return vs BCAB's -80.6%. The 3-year compound annual growth rate (CAGR) favors ABBV at 14.6% vs BCAB's -70.1% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -83.7% | -10.1% | +6.3% | +7.6% | -8.5% |
| 1-Year ReturnPast 12 months | -80.6% | +11.3% | +46.1% | +23.4% | +27.1% |
| 3-Year ReturnCumulative with dividends | -97.3% | +50.4% | +2.9% | -7.1% | -5.1% |
| 5-Year ReturnCumulative with dividends | -99.8% | +101.3% | +70.2% | +5.2% | +43.6% |
| 10-Year ReturnCumulative with dividends | -99.7% | +295.5% | +166.5% | +6.7% | +90.0% |
| CAGR (3Y)Annualised 3-year return | -70.1% | +14.6% | +0.9% | -2.4% | -1.7% |
Risk & Volatility
Evenly matched — ABBV and MRK each lead in 1 of 2 comparable metrics.
Risk & Volatility
ABBV is the less volatile stock with a 0.34 beta — it tends to amplify market swings less than REGN's 0.81 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. MRK currently trades 89.7% from its 52-week high vs BCAB's 6.1% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.51x | 0.34x | 0.48x | 0.50x | 0.81x |
| 52-Week HighHighest price in past year | $71.50 | $244.81 | $125.14 | $62.89 | $821.11 |
| 52-Week LowLowest price in past year | $0.33 | $176.57 | $73.31 | $42.52 | $476.49 |
| % of 52W HighCurrent price vs 52-week peak | +6.1% | +82.8% | +89.7% | +89.4% | +86.4% |
| RSI (14)Momentum oscillator 0–100 | 40.5 | 46.8 | 46.7 | 41.4 | 44.9 |
| Avg Volume (50D)Average daily shares traded | 40K | 5.8M | 7.3M | 10.3M | 631K |
Analyst Outlook
Evenly matched — MRK and BMY each lead in 1 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: BCAB as "Buy", ABBV as "Buy", MRK as "Buy", BMY as "Hold", REGN as "Buy". Consensus price targets imply 5647.1% upside for BCAB (target: $250) vs 10.2% for BMY (target: $62). For income investors, BMY offers the higher dividend yield at 4.39% vs REGN's 0.48%.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Hold | Buy |
| Price TargetConsensus 12-month target | $250.00 | $256.64 | $129.31 | $62.00 | $865.68 |
| # AnalystsCovering analysts | 9 | 41 | 37 | 41 | 48 |
| Dividend YieldAnnual dividend ÷ price | — | +3.2% | +2.9% | +4.4% | +0.5% |
| Dividend StreakConsecutive years of raises | — | 13 | 14 | 6 | 1 |
| Dividend / ShareAnnual DPS | — | $6.57 | $3.26 | $2.47 | $3.41 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +0.3% | +1.8% | 0.0% | +5.4% |
BMY leads in 1 of 6 categories (Valuation Metrics). REGN leads in 1 (Profitability & Efficiency). 3 tied.
BCAB vs ABBV vs MRK vs BMY vs REGN: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is BCAB or ABBV or MRK or BMY or REGN a better buy right now?
For growth investors, AbbVie Inc.
(ABBV) is the stronger pick with 8. 6% revenue growth year-over-year, versus -81. 8% for BioAtla, Inc. (BCAB). Merck & Co. , Inc. (MRK) offers the better valuation at 15. 4x trailing P/E (21. 9x forward), making it the more compelling value choice. Analysts rate BioAtla, Inc. (BCAB) a "Buy" — based on 9 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — BCAB or ABBV or MRK or BMY or REGN?
On trailing P/E, Merck & Co.
, Inc. (MRK) is the cheapest at 15. 4x versus AbbVie Inc. at 85. 5x. On forward P/E, Bristol-Myers Squibb Company is actually cheaper at 8. 9x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Merck & Co. , Inc. wins at 1. 03x versus Regeneron Pharmaceuticals, Inc. 's 2. 43x — a reasonable growth-adjusted valuation.
03Which is the better long-term investment — BCAB or ABBV or MRK or BMY or REGN?
Over the past 5 years, AbbVie Inc.
(ABBV) delivered a total return of +101. 3%, compared to -99. 8% for BioAtla, Inc. (BCAB). Over 10 years, the gap is even starker: ABBV returned +295. 5% versus BCAB's -99. 7%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — BCAB or ABBV or MRK or BMY or REGN?
By beta (market sensitivity over 5 years), AbbVie Inc.
(ABBV) is the lower-risk stock at 0. 34β versus Regeneron Pharmaceuticals, Inc. 's 0. 81β — meaning REGN is approximately 138% more volatile than ABBV relative to the S&P 500. On balance sheet safety, Regeneron Pharmaceuticals, Inc. (REGN) carries a lower debt/equity ratio of 9% versus 3% for Bristol-Myers Squibb Company — giving it more financial flexibility in a downturn.
05Which is growing faster — BCAB or ABBV or MRK or BMY or REGN?
By revenue growth (latest reported year), AbbVie Inc.
(ABBV) is pulling ahead at 8. 6% versus -81. 8% for BioAtla, Inc. (BCAB). On earnings-per-share growth, the picture is similar: Bristol-Myers Squibb Company grew EPS 178. 2% year-over-year, compared to -0. 8% for AbbVie Inc.. Over a 3-year CAGR, REGN leads at 5. 6% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — BCAB or ABBV or MRK or BMY or REGN?
Regeneron Pharmaceuticals, Inc.
(REGN) is the more profitable company, earning 31. 4% net margin versus -29. 8% for BioAtla, Inc. — meaning it keeps 31. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: MRK leads at 36. 2% versus -29. 7% for BCAB. At the gross margin level — before operating expenses — BCAB leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is BCAB or ABBV or MRK or BMY or REGN more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, Merck & Co. , Inc. (MRK) is the more undervalued stock at a PEG of 1. 03x versus Regeneron Pharmaceuticals, Inc. 's 2. 43x. A PEG below 1. 5 suggests fair-to-attractive pricing relative to expected growth. On forward earnings alone, Bristol-Myers Squibb Company (BMY) trades at 8. 9x forward P/E versus 21. 9x for Merck & Co. , Inc. — 13. 0x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for BCAB: 5647. 1% to $250. 00.
08Which pays a better dividend — BCAB or ABBV or MRK or BMY or REGN?
In this comparison, BMY (4.
4% yield), ABBV (3. 2% yield), MRK (2. 9% yield), REGN (0. 5% yield) pay a dividend. BCAB does not pay a meaningful dividend and should not be held primarily for income.
09Is BCAB or ABBV or MRK or BMY or REGN better for a retirement portfolio?
For long-horizon retirement investors, AbbVie Inc.
(ABBV) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 34), 3. 2% yield, +295. 5% 10Y return). Both have compounded well over 10 years (ABBV: +295. 5%, REGN: +90. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between BCAB and ABBV and MRK and BMY and REGN?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: BCAB is a small-cap quality compounder stock; ABBV is a large-cap income-oriented stock; MRK is a large-cap deep-value stock; BMY is a mid-cap deep-value stock; REGN is a mid-cap deep-value stock. ABBV, MRK, BMY pay a dividend while BCAB, REGN do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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