Biotechnology
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BCDA vs MCRB vs ANIK vs NVCR vs ADMA
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Medical - Devices
Medical - Instruments & Supplies
Biotechnology
BCDA vs MCRB vs ANIK vs NVCR vs ADMA — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Medical - Devices | Medical - Instruments & Supplies | Biotechnology |
| Market Cap | $5M | $74M | $203M | $1.92B | $2.03B |
| Revenue (TTM) | $0.00 | $1M | $116M | $674M | $510M |
| Net Income (TTM) | $-9M | $-47M | $-11M | $-173M | $165M |
| Gross Margin | -74.6% | 16.0% | 58.6% | 75.2% | 61.3% |
| Operating Margin | -137.9% | -76.4% | -10.5% | -27.2% | 42.1% |
| Forward P/E | — | 12.1x | — | — | 8.9x |
| Total Debt | $951K | $83M | $24M | $290M | $80M |
| Cash & Equiv. | $2M | $46M | $57M | $103M | $88M |
BCDA vs MCRB vs ANIK vs NVCR vs ADMA — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| BioCardia, Inc. (BCDA) | 100 | 0.6 | -99.4% |
| Seres Therapeutics,… (MCRB) | 100 | 7.0 | -93.0% |
| Anika Therapeutics,… (ANIK) | 100 | 45.2 | -54.8% |
| NovoCure Limited (NVCR) | 100 | 25.0 | -75.0% |
| ADMA Biologics, Inc. (ADMA) | 100 | 257.4 | +157.4% |
Price return only. Dividends and distributions are not included.
Quick Verdict: BCDA vs MCRB vs ANIK vs NVCR vs ADMA
Each card shows where this stock fits in a portfolio — not just who wins on paper.
BCDA is the #2 pick in this set and the best alternative if income & stability is your priority.
- Dividend streak 1 yrs, beta 1.14
- Beta 1.14 vs NVCR's 2.20
MCRB lags the leaders in this set but could rank higher in a more targeted comparison.
ANIK ranks third and is worth considering specifically for sleep-well-at-night and defensive.
- Lower volatility, beta 1.14, Low D/E 16.9%, current ratio 4.72x
- Beta 1.14, current ratio 4.72x
- +4.5% vs ADMA's -64.1%
Among these 5 stocks, NVCR doesn't own a clear edge in any measured category.
ADMA carries the broadest edge in this set and is the clearest fit for growth exposure and long-term compounding.
- Rev growth 19.6%, EPS growth -25.9%, 3Y rev CAGR 49.0%
- 39.8% 10Y total return vs NVCR's 30.3%
- 19.6% revenue growth vs MCRB's -153.7%
- Better valuation composite
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 19.6% revenue growth vs MCRB's -153.7% | |
| Value | Better valuation composite | |
| Quality / Margins | 32.4% margin vs BCDA's -137.0% | |
| Stability / Safety | Beta 1.14 vs NVCR's 2.20 | |
| Dividends | Tie | None of these 5 stocks pay a meaningful dividend |
| Momentum (1Y) | +4.5% vs ADMA's -64.1% | |
| Efficiency (ROA) | 27.4% ROA vs BCDA's -138.9% |
BCDA vs MCRB vs ANIK vs NVCR vs ADMA — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
BCDA vs MCRB vs ANIK vs NVCR vs ADMA — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
ADMA leads in 3 of 6 categories
ANIK leads 1 • BCDA leads 0 • MCRB leads 0 • NVCR leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
ADMA leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
NVCR and BCDA operate at a comparable scale, with $674M and $0 in trailing revenue. ADMA is the more profitable business, keeping 32.4% of every revenue dollar as net income compared to BCDA's -137.0%. On growth, ANIK holds the edge at +13.2% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $1M | $116M | $674M | $510M |
| EBITDAEarnings before interest/tax | -$8M | -$83M | -$7M | -$165M | $221M |
| Net IncomeAfter-tax profit | -$9M | -$47M | -$11M | -$173M | $165M |
| Free Cash FlowCash after capex | -$8M | -$42M | $1M | -$48M | $108M |
| Gross MarginGross profit ÷ Revenue | -74.6% | +16.0% | +58.6% | +75.2% | +61.3% |
| Operating MarginEBIT ÷ Revenue | -137.9% | -76.4% | -10.5% | -27.2% | +42.1% |
| Net MarginNet income ÷ Revenue | -137.0% | -40.9% | -9.5% | -25.7% | +32.4% |
| FCF MarginFCF ÷ Revenue | -138.5% | -36.9% | +0.9% | -7.1% | +21.2% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | — | +13.2% | +12.3% | -0.3% |
| EPS Growth (YoY)Latest quarter vs prior year | -386.3% | -155.5% | -8.8% | -100.0% | +72.7% |
Valuation Metrics
ANIK leads this category, winning 4 of 4 comparable metrics.
Valuation Metrics
At 12.1x trailing earnings, MCRB trades at a 15% valuation discount to ADMA's 14.1x P/E.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $5M | $74M | $203M | $1.9B | $2.0B |
| Enterprise ValueMkt cap + debt − cash | $4M | $112M | $170M | $2.1B | $2.0B |
| Trailing P/EPrice ÷ TTM EPS | -0.38x | 12.06x | -19.92x | -13.80x | 14.12x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — | 8.88x |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | — | 10.15x |
| Price / SalesMarket cap ÷ Revenue | 86.47x | 94.25x | 1.80x | 2.92x | 3.98x |
| Price / BookPrice ÷ Book value/share | 3.57x | 1.55x | 1.51x | 5.51x | 4.35x |
| Price / FCFMarket cap ÷ FCF | — | 85.97x | 46.51x | — | 73.05x |
Profitability & Efficiency
ADMA leads this category, winning 6 of 9 comparable metrics.
Profitability & Efficiency
ADMA delivers a 39.0% return on equity — every $100 of shareholder capital generates $39 in annual profit, vs $-3 for BCDA. ADMA carries lower financial leverage with a 0.17x debt-to-equity ratio, signaling a more conservative balance sheet compared to MCRB's 1.88x. On the Piotroski fundamental quality scale (0–9), MCRB scores 7/9 vs BCDA's 2/9, reflecting strong financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -3.3% | -127.3% | -7.7% | -50.8% | +39.0% |
| ROA (TTM)Return on assets | -138.9% | -34.5% | -5.9% | -16.5% | +27.4% |
| ROICReturn on invested capital | — | -90.3% | -7.1% | -16.4% | +36.0% |
| ROCEReturn on capital employed | -20.5% | -86.4% | -6.4% | -28.9% | +38.8% |
| Piotroski ScoreFundamental quality 0–9 | 2 | 7 | 6 | 5 | 5 |
| Debt / EquityFinancial leverage | 1.14x | 1.88x | 0.17x | 0.85x | 0.17x |
| Net DebtTotal debt minus cash | -$1M | $37M | -$33M | $187M | -$8M |
| Cash & Equiv.Liquid assets | $2M | $46M | $57M | $103M | $88M |
| Total DebtShort + long-term debt | $951,000 | $83M | $24M | $290M | $80M |
| Interest CoverageEBIT ÷ Interest expense | — | — | — | -96.80x | 50.85x |
Total Returns (Dividends Reinvested)
ADMA leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ADMA five years ago would be worth $48,678 today (with dividends reinvested), compared to $70 for BCDA. Over the past 12 months, ANIK leads with a +4.5% total return vs ADMA's -64.1%. The 3-year compound annual growth rate (CAGR) favors ADMA at 34.3% vs BCDA's -77.2% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -14.2% | -49.0% | +61.9% | +28.3% | -52.6% |
| 1-Year ReturnPast 12 months | -58.9% | -6.9% | +4.5% | +1.1% | -64.1% |
| 3-Year ReturnCumulative with dividends | -98.8% | -93.1% | -41.7% | -75.7% | +142.0% |
| 5-Year ReturnCumulative with dividends | -99.3% | -98.1% | -63.9% | -91.3% | +386.8% |
| 10-Year ReturnCumulative with dividends | -99.7% | -98.5% | -65.9% | +30.3% | +39.8% |
| CAGR (3Y)Annualised 3-year return | -77.2% | -58.9% | -16.5% | -37.6% | +34.3% |
Risk & Volatility
Evenly matched — BCDA and ANIK each lead in 1 of 2 comparable metrics.
Risk & Volatility
BCDA is the less volatile stock with a 1.14 beta — it tends to amplify market swings less than NVCR's 2.20 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ANIK currently trades 93.2% from its 52-week high vs MCRB's 25.8% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.14x | 1.69x | 1.14x | 2.20x | 1.22x |
| 52-Week HighHighest price in past year | $2.92 | $29.98 | $16.24 | $20.06 | $23.98 |
| 52-Week LowLowest price in past year | $1.00 | $6.53 | $7.87 | $9.82 | $7.21 |
| % of 52W HighCurrent price vs 52-week peak | +37.3% | +25.8% | +93.2% | +83.9% | +35.3% |
| RSI (14)Momentum oscillator 0–100 | 41.2 | 46.4 | 53.3 | 69.8 | 37.9 |
| Avg Volume (50D)Average daily shares traded | 62K | 50K | 135K | 1.5M | 7.3M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: MCRB as "Buy", ANIK as "Buy", NVCR as "Buy", ADMA as "Buy". Consensus price targets imply 165.6% upside for ADMA (target: $23) vs -83.8% for MCRB (target: $1).
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | — | $1.25 | — | $33.50 | $22.50 |
| # AnalystsCovering analysts | — | 18 | 6 | 15 | 9 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — | — |
| Dividend StreakConsecutive years of raises | 1 | — | — | — | 1 |
| Dividend / ShareAnnual DPS | — | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | +4.7% | 0.0% | +1.6% |
ADMA leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). ANIK leads in 1 (Valuation Metrics). 1 tied.
BCDA vs MCRB vs ANIK vs NVCR vs ADMA: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is BCDA or MCRB or ANIK or NVCR or ADMA a better buy right now?
For growth investors, ADMA Biologics, Inc.
(ADMA) is the stronger pick with 19. 6% revenue growth year-over-year, versus -87. 8% for BioCardia, Inc. (BCDA). Seres Therapeutics, Inc. (MCRB) offers the better valuation at 12. 1x trailing P/E, making it the more compelling value choice. Analysts rate Seres Therapeutics, Inc. (MCRB) a "Buy" — based on 18 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — BCDA or MCRB or ANIK or NVCR or ADMA?
On trailing P/E, Seres Therapeutics, Inc.
(MCRB) is the cheapest at 12. 1x versus ADMA Biologics, Inc. at 14. 1x.
03Which is the better long-term investment — BCDA or MCRB or ANIK or NVCR or ADMA?
Over the past 5 years, ADMA Biologics, Inc.
(ADMA) delivered a total return of +386. 8%, compared to -99. 3% for BioCardia, Inc. (BCDA). Over 10 years, the gap is even starker: ADMA returned +39. 8% versus BCDA's -99. 7%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — BCDA or MCRB or ANIK or NVCR or ADMA?
By beta (market sensitivity over 5 years), BioCardia, Inc.
(BCDA) is the lower-risk stock at 1. 14β versus NovoCure Limited's 2. 20β — meaning NVCR is approximately 93% more volatile than BCDA relative to the S&P 500. On balance sheet safety, ADMA Biologics, Inc. (ADMA) carries a lower debt/equity ratio of 17% versus 188% for Seres Therapeutics, Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — BCDA or MCRB or ANIK or NVCR or ADMA?
By revenue growth (latest reported year), ADMA Biologics, Inc.
(ADMA) is pulling ahead at 19. 6% versus -87. 8% for BioCardia, Inc. (BCDA). On earnings-per-share growth, the picture is similar: Seres Therapeutics, Inc. grew EPS 103. 4% year-over-year, compared to -25. 9% for ADMA Biologics, Inc.. Over a 3-year CAGR, ADMA leads at 49. 0% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — BCDA or MCRB or ANIK or NVCR or ADMA?
Seres Therapeutics, Inc.
(MCRB) is the more profitable company, earning 721. 9% net margin versus -137. 0% for BioCardia, Inc. — meaning it keeps 721. 9% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ADMA leads at 37. 5% versus -137. 9% for BCDA. At the gross margin level — before operating expenses — NVCR leads at 74. 5%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is BCDA or MCRB or ANIK or NVCR or ADMA more undervalued right now?
Analyst consensus price targets imply the most upside for ADMA: 165.
6% to $22. 50.
08Which pays a better dividend — BCDA or MCRB or ANIK or NVCR or ADMA?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
09Is BCDA or MCRB or ANIK or NVCR or ADMA better for a retirement portfolio?
For long-horizon retirement investors, ADMA Biologics, Inc.
(ADMA) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 22)). NovoCure Limited (NVCR) carries a higher beta of 2. 20 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ADMA: +39. 8%, NVCR: +30. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between BCDA and MCRB and ANIK and NVCR and ADMA?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: BCDA is a small-cap quality compounder stock; MCRB is a small-cap deep-value stock; ANIK is a small-cap quality compounder stock; NVCR is a small-cap quality compounder stock; ADMA is a small-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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