Medical - Healthcare Information Services
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BFRG vs ABSI vs RXRX vs SDGR
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Medical - Healthcare Information Services
BFRG vs ABSI vs RXRX vs SDGR — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Medical - Healthcare Information Services | Biotechnology | Biotechnology | Medical - Healthcare Information Services |
| Market Cap | $7M | $894M | $1.46B | $992M |
| Revenue (TTM) | $117K | $2M | $66M | $255M |
| Net Income (TTM) | $-7M | $-118M | $-560M | $-103M |
| Gross Margin | 18.8% | -13.4% | -34.4% | 55.3% |
| Operating Margin | -58.8% | -60.3% | -8.8% | -64.7% |
| Total Debt | $0.00 | $5M | $78M | $109M |
| Cash & Equiv. | $2.18T | $20M | $743M | $231M |
BFRG vs ABSI vs RXRX vs SDGR — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Feb 23 | May 26 | Return |
|---|---|---|---|
| Bullfrog AI Holding… (BFRG) | 100 | 13.6 | -86.4% |
| Absci Corporation (ABSI) | 100 | 271.2 | +171.2% |
| Recursion Pharmaceu… (RXRX) | 100 | 40.1 | -59.9% |
| Schrödinger, Inc. (SDGR) | 100 | 61.1 | -38.9% |
Price return only. Dividends and distributions are not included.
Quick Verdict: BFRG vs ABSI vs RXRX vs SDGR
Each card shows where this stock fits in a portfolio — not just who wins on paper.
BFRG lags the leaders in this set but could rank higher in a more targeted comparison.
ABSI is the #2 pick in this set and the best alternative if sleep-well-at-night and defensive is your priority.
- Lower volatility, beta 2.82, Low D/E 2.8%, current ratio 6.57x
- Beta 2.82, current ratio 6.57x
- +116.2% vs BFRG's -62.0%
RXRX is the clearest fit if your priority is growth exposure.
- Rev growth 26.9%, EPS growth 14.8%, 3Y rev CAGR 23.5%
- 26.9% revenue growth vs ABSI's -38.2%
SDGR carries the broadest edge in this set and is the clearest fit for income & stability and long-term compounding.
- beta 1.72
- -53.6% 10Y total return vs ABSI's -73.4%
- -40.6% margin vs ABSI's -73.1%
- Beta 1.72 vs RXRX's 3.18
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 26.9% revenue growth vs ABSI's -38.2% | |
| Quality / Margins | -40.6% margin vs ABSI's -73.1% | |
| Stability / Safety | Beta 1.72 vs RXRX's 3.18 | |
| Dividends | Tie | None of these 4 stocks pay a meaningful dividend |
| Momentum (1Y) | +116.2% vs BFRG's -62.0% | |
| Efficiency (ROA) | -15.3% ROA vs BFRG's -177.1% |
BFRG vs ABSI vs RXRX vs SDGR — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
BFRG vs ABSI vs RXRX vs SDGR — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
SDGR leads in 2 of 6 categories
BFRG leads 1 • ABSI leads 1 • RXRX leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
SDGR leads this category, winning 5 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
SDGR is the larger business by revenue, generating $255M annually — 2184.8x BFRG's $116,670. SDGR is the more profitable business, keeping -40.6% of every revenue dollar as net income compared to ABSI's -73.1%. On growth, SDGR holds the edge at -1.6% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $116,670 | $2M | $66M | $255M |
| EBITDAEarnings before interest/tax | -$7M | -$116M | -$521M | -$159M |
| Net IncomeAfter-tax profit | -$7M | -$118M | -$560M | -$103M |
| Free Cash FlowCash after capex | -$6M | -$99M | -$326M | -$148M |
| Gross MarginGross profit ÷ Revenue | +18.8% | -13.4% | -34.4% | +55.3% |
| Operating MarginEBIT ÷ Revenue | -58.8% | -60.3% | -8.8% | -64.7% |
| Net MarginNet income ÷ Revenue | -57.7% | -73.1% | -8.4% | -40.6% |
| FCF MarginFCF ÷ Revenue | -48.1% | -60.8% | -4.9% | -58.2% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | -100.0% | -56.1% | -1.6% |
| EPS Growth (YoY)Latest quarter vs prior year | +31.8% | +9.5% | +56.0% | +1.2% |
Valuation Metrics
BFRG leads this category, winning 2 of 3 comparable metrics.
Valuation Metrics
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $7M | $894M | $1.5B | $992M |
| Enterprise ValueMkt cap + debt − cash | -$2.18T | $879M | $797M | $871M |
| Trailing P/EPrice ÷ TTM EPS | -1.03x | -6.85x | -2.27x | -9.42x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | — |
| Price / SalesMarket cap ÷ Revenue | 0.00x | 319.22x | 19.58x | 3.88x |
| Price / BookPrice ÷ Book value/share | 0.00x | 4.15x | 1.29x | 2.68x |
| Price / FCFMarket cap ÷ FCF | — | — | — | 79.66x |
Profitability & Efficiency
SDGR leads this category, winning 5 of 9 comparable metrics.
Profitability & Efficiency
SDGR delivers a -30.8% return on equity — every $100 of shareholder capital generates $-31 in annual profit, vs $-2 for BFRG. ABSI carries lower financial leverage with a 0.03x debt-to-equity ratio, signaling a more conservative balance sheet compared to SDGR's 0.30x. On the Piotroski fundamental quality scale (0–9), ABSI scores 4/9 vs BFRG's 3/9, reflecting mixed financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -2.2% | -63.6% | -54.3% | -30.8% |
| ROA (TTM)Return on assets | -177.1% | -54.7% | -40.6% | -15.3% |
| ROICReturn on invested capital | — | -58.0% | -95.8% | -39.4% |
| ROCEReturn on capital employed | -6.2% | -65.9% | -50.1% | -28.6% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 4 | 4 | 4 |
| Debt / EquityFinancial leverage | — | 0.03x | 0.07x | 0.30x |
| Net DebtTotal debt minus cash | -$2.18T | -$15M | -$665M | -$121M |
| Cash & Equiv.Liquid assets | $2.18T | $20M | $743M | $231M |
| Total DebtShort + long-term debt | $0 | $5M | $78M | $109M |
| Interest CoverageEBIT ÷ Interest expense | -958.75x | -865.97x | -336.46x | — |
Total Returns (Dividends Reinvested)
ABSI leads this category, winning 5 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ABSI five years ago would be worth $2,663 today (with dividends reinvested), compared to $1,000 for BFRG. Over the past 12 months, ABSI leads with a +116.2% total return vs BFRG's -62.0%. The 3-year compound annual growth rate (CAGR) favors ABSI at 59.4% vs BFRG's -42.6% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | -26.2% | +59.3% | -22.1% | -26.1% |
| 1-Year ReturnPast 12 months | -62.0% | +116.2% | -22.0% | -44.0% |
| 3-Year ReturnCumulative with dividends | -81.1% | +304.9% | -41.6% | -52.1% |
| 5-Year ReturnCumulative with dividends | -90.0% | -73.4% | -88.2% | -80.6% |
| 10-Year ReturnCumulative with dividends | -90.0% | -73.4% | -81.8% | -53.6% |
| CAGR (3Y)Annualised 3-year return | -42.6% | +59.4% | -16.4% | -21.8% |
Risk & Volatility
Evenly matched — ABSI and SDGR each lead in 1 of 2 comparable metrics.
Risk & Volatility
SDGR is the less volatile stock with a 1.72 beta — it tends to amplify market swings less than RXRX's 3.18 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ABSI currently trades 92.2% from its 52-week high vs BFRG's 31.8% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 3.07x | 2.82x | 3.18x | 1.72x |
| 52-Week HighHighest price in past year | $2.04 | $6.24 | $7.18 | $27.63 |
| 52-Week LowLowest price in past year | $0.42 | $2.24 | $2.80 | $10.95 |
| % of 52W HighCurrent price vs 52-week peak | +31.8% | +92.2% | +45.5% | +48.1% |
| RSI (14)Momentum oscillator 0–100 | 42.2 | 83.6 | 49.5 | 59.8 |
| Avg Volume (50D)Average daily shares traded | 13.6M | 4.4M | 12.5M | 1.3M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: ABSI as "Buy", RXRX as "Hold", SDGR as "Buy". Consensus price targets imply 236.4% upside for RXRX (target: $11) vs 7.1% for ABSI (target: $6).
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | Hold | Buy |
| Price TargetConsensus 12-month target | — | $6.16 | $11.00 | $18.00 |
| # AnalystsCovering analysts | — | 12 | 10 | 12 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | — | — | — |
| Dividend / ShareAnnual DPS | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | 0.0% |
SDGR leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). BFRG leads in 1 (Valuation Metrics). 1 tied.
BFRG vs ABSI vs RXRX vs SDGR: Key Questions Answered
8 questions · data-driven answers · updated daily
01Is BFRG or ABSI or RXRX or SDGR a better buy right now?
For growth investors, Recursion Pharmaceuticals, Inc.
(RXRX) is the stronger pick with 26. 9% revenue growth year-over-year, versus -38. 2% for Absci Corporation (ABSI). Analysts rate Absci Corporation (ABSI) a "Buy" — based on 12 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — BFRG or ABSI or RXRX or SDGR?
Over the past 5 years, Absci Corporation (ABSI) delivered a total return of -73.
4%, compared to -90. 0% for Bullfrog AI Holdings, Inc. Common Stock (BFRG). Over 10 years, the gap is even starker: SDGR returned -53. 6% versus BFRG's -90. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — BFRG or ABSI or RXRX or SDGR?
By beta (market sensitivity over 5 years), Schrödinger, Inc.
(SDGR) is the lower-risk stock at 1. 72β versus Recursion Pharmaceuticals, Inc. 's 3. 18β — meaning RXRX is approximately 84% more volatile than SDGR relative to the S&P 500. On balance sheet safety, Absci Corporation (ABSI) carries a lower debt/equity ratio of 3% versus 30% for Schrödinger, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — BFRG or ABSI or RXRX or SDGR?
By revenue growth (latest reported year), Recursion Pharmaceuticals, Inc.
(RXRX) is pulling ahead at 26. 9% versus -38. 2% for Absci Corporation (ABSI). On earnings-per-share growth, the picture is similar: Schrödinger, Inc. grew EPS 45. 1% year-over-year, compared to 10. 6% for Absci Corporation. Over a 3-year CAGR, BFRG leads at 225. 8% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — BFRG or ABSI or RXRX or SDGR?
Schrödinger, Inc.
(SDGR) is the more profitable company, earning -40. 4% net margin versus -55. 7% for Bullfrog AI Holdings, Inc. Common Stock — meaning it keeps -40. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: SDGR leads at -65. 2% versus -56. 5% for BFRG. At the gross margin level — before operating expenses — SDGR leads at 55. 7%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — BFRG or ABSI or RXRX or SDGR?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is BFRG or ABSI or RXRX or SDGR better for a retirement portfolio?
For long-horizon retirement investors, Schrödinger, Inc.
(SDGR) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding. Bullfrog AI Holdings, Inc. Common Stock (BFRG) carries a higher beta of 3. 07 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (SDGR: -53. 6%, BFRG: -90. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between BFRG and ABSI and RXRX and SDGR?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: BFRG is a small-cap quality compounder stock; ABSI is a small-cap quality compounder stock; RXRX is a small-cap high-growth stock; SDGR is a small-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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