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BIAF vs TMO vs DHR vs NVCR vs HOLX

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
BIAF
bioAffinity Technologies, Inc.

Medical - Diagnostics & Research

HealthcareNASDAQ • US
Market Cap$821K
5Y Perf.-97.7%
TMO
Thermo Fisher Scientific Inc.

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$172.80B
5Y Perf.-8.3%
DHR
Danaher Corporation

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$121.14B
5Y Perf.-25.2%
NVCR
NovoCure Limited

Medical - Instruments & Supplies

HealthcareNASDAQ • JE
Market Cap$2.04B
5Y Perf.-76.5%
HOLX
Hologic, Inc.

Medical - Instruments & Supplies

HealthcareNASDAQ • US
Market Cap$16.97B
5Y Perf.+17.2%

BIAF vs TMO vs DHR vs NVCR vs HOLX — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
BIAF logoBIAF
TMO logoTMO
DHR logoDHR
NVCR logoNVCR
HOLX logoHOLX
IndustryMedical - Diagnostics & ResearchMedical - Diagnostics & ResearchMedical - Diagnostics & ResearchMedical - Instruments & SuppliesMedical - Instruments & Supplies
Market Cap$821K$172.80B$121.14B$2.04B$16.97B
Revenue (TTM)$7M$45.20B$24.78B$674M$4.13B
Net Income (TTM)$-15M$6.86B$3.69B$-173M$544M
Gross Margin23.9%39.4%60.7%75.2%52.8%
Operating Margin-153.2%17.8%21.0%-27.2%17.5%
Forward P/E18.7x20.3x17.2x
Total Debt$2M$40.85B$18.42B$290M$2.63B
Cash & Equiv.$1M$9.86B$4.62B$103M$1.96B

BIAF vs TMO vs DHR vs NVCR vs HOLXLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

BIAF
TMO
DHR
NVCR
HOLX
StockSep 22May 26Return
bioAffinity Technol… (BIAF)1002.3-97.7%
Thermo Fisher Scien… (TMO)10091.7-8.3%
Danaher Corporation (DHR)10074.8-25.2%
NovoCure Limited (NVCR)10023.5-76.5%
Hologic, Inc. (HOLX)100117.2+17.2%

Price return only. Dividends and distributions are not included.

Quick Verdict: BIAF vs TMO vs DHR vs NVCR vs HOLX

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: TMO and HOLX are tied at the top with 3 categories each (5-stock set) — the right choice depends on your priorities. Hologic, Inc. is the stronger pick specifically for valuation and capital efficiency and capital preservation and lower volatility. BIAF also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
BIAF
bioAffinity Technologies, Inc.
The Growth Leader

BIAF ranks third and is worth considering specifically for growth.

  • 269.7% revenue growth vs HOLX's 1.7%
Best for: growth
TMO
Thermo Fisher Scientific Inc.
The Long-Run Compounder

TMO carries the broadest edge in this set and is the clearest fit for long-term compounding and valuation efficiency.

  • 222.6% 10Y total return vs HOLX's 124.3%
  • PEG 8.86 vs DHR's 33.47
  • 15.2% margin vs BIAF's -217.5%
  • 0.4% yield, 8-year raise streak, vs DHR's 0.7%, (3 stocks pay no dividend)
Best for: long-term compounding and valuation efficiency
DHR
Danaher Corporation
The Income Pick

DHR is the clearest fit if your priority is income & stability and defensive.

  • Dividend streak 1 yrs, beta 0.89, yield 0.7%
  • Beta 0.89, yield 0.7%, current ratio 1.87x
Best for: income & stability and defensive
NVCR
NovoCure Limited
The Growth Play

NVCR is the clearest fit if your priority is growth exposure.

  • Rev growth 8.3%, EPS growth 21.8%, 3Y rev CAGR 6.8%
Best for: growth exposure
HOLX
Hologic, Inc.
The Defensive Pick

HOLX is the #2 pick in this set and the best alternative if sleep-well-at-night is your priority.

  • Lower volatility, beta 0.45, Low D/E 52.0%, current ratio 3.75x
  • Better valuation composite
  • Beta 0.45 vs BIAF's 2.18, lower leverage
  • +35.3% vs BIAF's -66.4%
Best for: sleep-well-at-night
See the full category breakdown
CategoryWinnerWhy
GrowthBIAF logoBIAF269.7% revenue growth vs HOLX's 1.7%
ValueHOLX logoHOLXBetter valuation composite
Quality / MarginsTMO logoTMO15.2% margin vs BIAF's -217.5%
Stability / SafetyHOLX logoHOLXBeta 0.45 vs BIAF's 2.18, lower leverage
DividendsTMO logoTMO0.4% yield, 8-year raise streak, vs DHR's 0.7%, (3 stocks pay no dividend)
Momentum (1Y)HOLX logoHOLX+35.3% vs BIAF's -66.4%
Efficiency (ROA)TMO logoTMO6.4% ROA vs BIAF's -127.7%, ROIC 7.5% vs -203.2%

BIAF vs TMO vs DHR vs NVCR vs HOLX — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

BIAFbioAffinity Technologies, Inc.
FY 2024
Health Care, Patient Service
100.0%$516,000
TMOThermo Fisher Scientific Inc.
FY 2025
Consumables
41.9%$18.7B
Service
41.7%$18.6B
Instruments
16.4%$7.3B
DHRDanaher Corporation
FY 2025
Revenue from Contract with Customer, Measurement, Recurring
81.9%$20.1B
Revenue from Contract with Customer, Measurement, Nonrecurring
18.1%$4.4B
NVCRNovoCure Limited

Segment breakdown not available.

HOLXHologic, Inc.
FY 2025
Diagnostics
44.6%$1.8B
Breast Health
36.2%$1.5B
Gyn Surgical
16.6%$680M
Skeletal Health
2.7%$109M

BIAF vs TMO vs DHR vs NVCR vs HOLX — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLHOLXLAGGINGNVCR

Income & Cash Flow (Last 12 Months)

Evenly matched — TMO and NVCR each lead in 2 of 6 comparable metrics.

TMO is the larger business by revenue, generating $45.2B annually — 6669.4x BIAF's $7M. TMO is the more profitable business, keeping 15.2% of every revenue dollar as net income compared to BIAF's -2.2%. On growth, NVCR holds the edge at +12.3% YoY revenue growth, suggesting stronger near-term business momentum.

MetricBIAF logoBIAFbioAffinity Techn…TMO logoTMOThermo Fisher Sci…DHR logoDHRDanaher Corporati…NVCR logoNVCRNovoCure LimitedHOLX logoHOLXHologic, Inc.
RevenueTrailing 12 months$7M$45.2B$24.8B$674M$4.1B
EBITDAEarnings before interest/tax-$10M$10.5B$7.2B-$165M$974M
Net IncomeAfter-tax profit-$15M$6.9B$3.7B-$173M$544M
Free Cash FlowCash after capex-$9M$6.7B$5.3B-$48M$1000M
Gross MarginGross profit ÷ Revenue+23.9%+39.4%+60.7%+75.2%+52.8%
Operating MarginEBIT ÷ Revenue-153.2%+17.8%+21.0%-27.2%+17.5%
Net MarginNet income ÷ Revenue-2.2%+15.2%+14.9%-25.7%+13.2%
FCF MarginFCF ÷ Revenue-125.5%+14.9%+21.4%-7.1%+24.2%
Rev. Growth (YoY)Latest quarter vs prior year-38.5%+6.2%+3.7%+12.3%+2.5%
EPS Growth (YoY)Latest quarter vs prior year+1.3%+11.3%+9.8%-100.0%-9.2%
Evenly matched — TMO and NVCR each lead in 2 of 6 comparable metrics.

Valuation Metrics

HOLX leads this category, winning 3 of 7 comparable metrics.

At 26.2x trailing earnings, TMO trades at a 23% valuation discount to DHR's 34.0x P/E. Adjusting for growth (PEG ratio), TMO offers better value at 12.41x vs DHR's 33.47x — a lower PEG means you pay less per unit of expected earnings growth.

MetricBIAF logoBIAFbioAffinity Techn…TMO logoTMOThermo Fisher Sci…DHR logoDHRDanaher Corporati…NVCR logoNVCRNovoCure LimitedHOLX logoHOLXHologic, Inc.
Market CapShares × price$820,796$172.8B$121.1B$2.0B$17.0B
Enterprise ValueMkt cap + debt − cash$1M$203.8B$134.9B$2.2B$17.6B
Trailing P/EPrice ÷ TTM EPS-0.09x26.21x33.96x-14.66x30.53x
Forward P/EPrice ÷ next-FY EPS est.18.71x20.29x17.21x
PEG RatioP/E ÷ EPS growth rate12.41x33.47x
EV / EBITDAEnterprise value multiple18.72x17.79x17.39x
Price / SalesMarket cap ÷ Revenue0.09x3.88x4.93x3.11x4.14x
Price / BookPrice ÷ Book value/share0.32x3.27x2.32x5.86x3.43x
Price / FCFMarket cap ÷ FCF27.46x23.03x18.44x
HOLX leads this category, winning 3 of 7 comparable metrics.

Profitability & Efficiency

Evenly matched — TMO and DHR each lead in 3 of 9 comparable metrics.

TMO delivers a 13.2% return on equity — every $100 of shareholder capital generates $13 in annual profit, vs $-166 for BIAF. DHR carries lower financial leverage with a 0.35x debt-to-equity ratio, signaling a more conservative balance sheet compared to NVCR's 0.85x. On the Piotroski fundamental quality scale (0–9), DHR scores 7/9 vs BIAF's 3/9, reflecting strong financial health.

MetricBIAF logoBIAFbioAffinity Techn…TMO logoTMOThermo Fisher Sci…DHR logoDHRDanaher Corporati…NVCR logoNVCRNovoCure LimitedHOLX logoHOLXHologic, Inc.
ROE (TTM)Return on equity-165.6%+13.2%+7.1%-50.8%+11.0%
ROA (TTM)Return on assets-127.7%+6.4%+4.5%-16.5%+6.1%
ROICReturn on invested capital-2.0%+7.5%+5.9%-16.4%+9.4%
ROCEReturn on capital employed-190.8%+9.1%+7.0%-28.9%+8.8%
Piotroski ScoreFundamental quality 0–936757
Debt / EquityFinancial leverage0.58x0.76x0.35x0.85x0.52x
Net DebtTotal debt minus cash$395,903$31.0B$13.8B$187M$667M
Cash & Equiv.Liquid assets$1M$9.9B$4.6B$103M$2.0B
Total DebtShort + long-term debt$2M$40.9B$18.4B$290M$2.6B
Interest CoverageEBIT ÷ Interest expense-259.85x5.89x18.13x-96.80x8.00x
Evenly matched — TMO and DHR each lead in 3 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

HOLX leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in HOLX five years ago would be worth $11,678 today (with dividends reinvested), compared to $82 for BIAF. Over the past 12 months, HOLX leads with a +35.3% total return vs BIAF's -66.4%. The 3-year compound annual growth rate (CAGR) favors HOLX at -2.9% vs BIAF's -67.6% — a key indicator of consistent wealth creation.

MetricBIAF logoBIAFbioAffinity Techn…TMO logoTMOThermo Fisher Sci…DHR logoDHRDanaher Corporati…NVCR logoNVCRNovoCure LimitedHOLX logoHOLXHologic, Inc.
YTD ReturnYear-to-date+66.4%-21.4%-25.5%+36.4%+1.9%
1-Year ReturnPast 12 months-66.4%+13.6%-11.4%+2.6%+35.3%
3-Year ReturnCumulative with dividends-96.6%-13.4%-17.6%-74.2%-8.5%
5-Year ReturnCumulative with dividends-99.2%+1.9%-23.2%-90.2%+16.8%
10-Year ReturnCumulative with dividends-99.2%+222.6%+212.4%+38.5%+124.3%
CAGR (3Y)Annualised 3-year return-67.6%-4.7%-6.3%-36.4%-2.9%
HOLX leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

HOLX leads this category, winning 2 of 2 comparable metrics.

HOLX is the less volatile stock with a 0.45 beta — it tends to amplify market swings less than BIAF's 2.18 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. HOLX currently trades 100.0% from its 52-week high vs BIAF's 13.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricBIAF logoBIAFbioAffinity Techn…TMO logoTMOThermo Fisher Sci…DHR logoDHRDanaher Corporati…NVCR logoNVCRNovoCure LimitedHOLX logoHOLXHologic, Inc.
Beta (5Y)Sensitivity to S&P 5002.18x1.07x0.89x2.15x0.45x
52-Week HighHighest price in past year$15.00$643.99$242.80$20.06$76.04
52-Week LowLowest price in past year$0.69$385.46$170.74$9.82$53.62
% of 52W HighCurrent price vs 52-week peak+13.5%+72.2%+70.5%+89.2%+100.0%
RSI (14)Momentum oscillator 0–10041.443.934.670.969.1
Avg Volume (50D)Average daily shares traded10.5M1.9M4.2M1.4M10.3M
HOLX leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Evenly matched — TMO and DHR each lead in 1 of 2 comparable metrics.

Analyst consensus: TMO as "Buy", DHR as "Buy", NVCR as "Buy", HOLX as "Hold". Consensus price targets imply 87.3% upside for NVCR (target: $34) vs 3.9% for HOLX (target: $79). For income investors, DHR offers the higher dividend yield at 0.72% vs TMO's 0.36%.

MetricBIAF logoBIAFbioAffinity Techn…TMO logoTMOThermo Fisher Sci…DHR logoDHRDanaher Corporati…NVCR logoNVCRNovoCure LimitedHOLX logoHOLXHologic, Inc.
Analyst RatingConsensus buy/hold/sellBuyBuyBuyHold
Price TargetConsensus 12-month target$654.67$247.00$33.50$79.00
# AnalystsCovering analysts42421542
Dividend YieldAnnual dividend ÷ price+0.4%+0.7%
Dividend StreakConsecutive years of raises81
Dividend / ShareAnnual DPS$1.69$1.23
Buyback YieldShare repurchases ÷ mkt cap0.0%+1.7%+2.5%0.0%+4.4%
Evenly matched — TMO and DHR each lead in 1 of 2 comparable metrics.
Key Takeaway

HOLX leads in 3 of 6 categories — strongest in Valuation Metrics and Total Returns. 3 categories are tied.

Best OverallHologic, Inc. (HOLX)Leads 3 of 6 categories
Loading custom metrics...

BIAF vs TMO vs DHR vs NVCR vs HOLX: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is BIAF or TMO or DHR or NVCR or HOLX a better buy right now?

For growth investors, bioAffinity Technologies, Inc.

(BIAF) is the stronger pick with 269. 7% revenue growth year-over-year, versus 1. 7% for Hologic, Inc. (HOLX). Thermo Fisher Scientific Inc. (TMO) offers the better valuation at 26. 2x trailing P/E (18. 7x forward), making it the more compelling value choice. Analysts rate Thermo Fisher Scientific Inc. (TMO) a "Buy" — based on 42 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — BIAF or TMO or DHR or NVCR or HOLX?

On trailing P/E, Thermo Fisher Scientific Inc.

(TMO) is the cheapest at 26. 2x versus Danaher Corporation at 34. 0x. On forward P/E, Hologic, Inc. is actually cheaper at 17. 2x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Thermo Fisher Scientific Inc. wins at 8. 86x versus Danaher Corporation's 33. 47x.

03

Which is the better long-term investment — BIAF or TMO or DHR or NVCR or HOLX?

Over the past 5 years, Hologic, Inc.

(HOLX) delivered a total return of +16. 8%, compared to -99. 2% for bioAffinity Technologies, Inc. (BIAF). Over 10 years, the gap is even starker: TMO returned +222. 6% versus BIAF's -99. 2%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — BIAF or TMO or DHR or NVCR or HOLX?

By beta (market sensitivity over 5 years), Hologic, Inc.

(HOLX) is the lower-risk stock at 0. 45β versus bioAffinity Technologies, Inc. 's 2. 18β — meaning BIAF is approximately 380% more volatile than HOLX relative to the S&P 500. On balance sheet safety, Danaher Corporation (DHR) carries a lower debt/equity ratio of 35% versus 85% for NovoCure Limited — giving it more financial flexibility in a downturn.

05

Which is growing faster — BIAF or TMO or DHR or NVCR or HOLX?

By revenue growth (latest reported year), bioAffinity Technologies, Inc.

(BIAF) is pulling ahead at 269. 7% versus 1. 7% for Hologic, Inc. (HOLX). On earnings-per-share growth, the picture is similar: NovoCure Limited grew EPS 21. 8% year-over-year, compared to -25. 0% for Hologic, Inc.. Over a 3-year CAGR, NVCR leads at 6. 8% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — BIAF or TMO or DHR or NVCR or HOLX?

Thermo Fisher Scientific Inc.

(TMO) is the more profitable company, earning 15. 1% net margin versus -96. 6% for bioAffinity Technologies, Inc. — meaning it keeps 15. 1% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: DHR leads at 20. 9% versus -95. 6% for BIAF. At the gross margin level — before operating expenses — NVCR leads at 74. 5%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is BIAF or TMO or DHR or NVCR or HOLX more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, Thermo Fisher Scientific Inc. (TMO) is the more undervalued stock at a PEG of 8. 86x versus Danaher Corporation's 33. 47x. Both stocks trade at elevated growth-adjusted valuations, so expected growth needs to materialise. On forward earnings alone, Hologic, Inc. (HOLX) trades at 17. 2x forward P/E versus 20. 3x for Danaher Corporation — 3. 1x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for NVCR: 87. 3% to $33. 50.

08

Which pays a better dividend — BIAF or TMO or DHR or NVCR or HOLX?

In this comparison, DHR (0.

7% yield), TMO (0. 4% yield) pay a dividend. BIAF, NVCR, HOLX do not pay a meaningful dividend and should not be held primarily for income.

09

Is BIAF or TMO or DHR or NVCR or HOLX better for a retirement portfolio?

For long-horizon retirement investors, Danaher Corporation (DHR) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

89), 0. 7% yield, +212. 4% 10Y return). bioAffinity Technologies, Inc. (BIAF) carries a higher beta of 2. 18 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (DHR: +212. 4%, BIAF: -99. 2%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between BIAF and TMO and DHR and NVCR and HOLX?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: BIAF is a small-cap high-growth stock; TMO is a mid-cap quality compounder stock; DHR is a mid-cap quality compounder stock; NVCR is a small-cap quality compounder stock; HOLX is a mid-cap quality compounder stock. DHR pays a dividend while BIAF, TMO, NVCR, HOLX do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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  • Net Margin > 7%
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