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BIOX vs PGEN vs FATE vs SNDX
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
BIOX vs PGEN vs FATE vs SNDX — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Agricultural Inputs | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $30M | $1.22B | $280M | $1.81B |
| Revenue (TTM) | $318M | $6M | $7M | $217M |
| Net Income (TTM) | $-53M | $-247M | $-136M | $-243M |
| Gross Margin | 39.1% | 23.0% | — | 98.0% |
| Operating Margin | 0.2% | -18.6% | -22.2% | -102.9% |
| Total Debt | $277M | $6M | $78M | $346M |
| Cash & Equiv. | $33M | $30M | $47M | $135M |
BIOX vs PGEN vs FATE vs SNDX — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Bioceres Crop Solut… (BIOX) | 100 | 7.1 | -92.9% |
| Precigen, Inc. (PGEN) | 100 | 188.6 | +88.6% |
| Fate Therapeutics, … (FATE) | 100 | 7.5 | -92.5% |
| Syndax Pharmaceutic… (SNDX) | 100 | 126.8 | +26.8% |
Price return only. Dividends and distributions are not included.
Quick Verdict: BIOX vs PGEN vs FATE vs SNDX
Each card shows where this stock fits in a portfolio — not just who wins on paper.
BIOX carries the broadest edge in this set and is the clearest fit for quality and efficiency.
- -16.6% margin vs PGEN's -39.1%
- -6.7% ROA vs PGEN's -144.1%, ROIC -0.5% vs -152.8%
PGEN is the clearest fit if your priority is sleep-well-at-night.
- Lower volatility, beta 1.44, Low D/E 14.3%, current ratio 4.76x
- +207.4% vs BIOX's -88.5%
FATE lags the leaders in this set but could rank higher in a more targeted comparison.
SNDX is the #2 pick in this set and the best alternative if income & stability and growth exposure is your priority.
- Dividend streak 1 yrs, beta 0.81
- Rev growth 6.3%, EPS growth 11.8%
- 43.4% 10Y total return vs FATE's 40.5%
- Beta 0.81, current ratio 4.40x
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 6.3% revenue growth vs FATE's -51.2% | |
| Quality / Margins | -16.6% margin vs PGEN's -39.1% | |
| Stability / Safety | Beta 0.81 vs FATE's 2.17 | |
| Dividends | Tie | None of these 4 stocks pay a meaningful dividend |
| Momentum (1Y) | +207.4% vs BIOX's -88.5% | |
| Efficiency (ROA) | -6.7% ROA vs PGEN's -144.1%, ROIC -0.5% vs -152.8% |
BIOX vs PGEN vs FATE vs SNDX — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
BIOX vs PGEN vs FATE vs SNDX — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
BIOX leads in 2 of 6 categories
PGEN leads 1 • FATE leads 0 • SNDX leads 0 • 2 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
Evenly matched — BIOX and SNDX each lead in 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
BIOX is the larger business by revenue, generating $318M annually — 50.4x PGEN's $6M. BIOX is the more profitable business, keeping -16.6% of every revenue dollar as net income compared to PGEN's -39.1%. On growth, SNDX holds the edge at +2.2% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $318M | $6M | $7M | $217M |
| EBITDAEarnings before interest/tax | $21M | -$115M | -$148M | -$218M |
| Net IncomeAfter-tax profit | -$53M | -$247M | -$136M | -$243M |
| Free Cash FlowCash after capex | $37M | -$76M | -$88M | -$278M |
| Gross MarginGross profit ÷ Revenue | +39.1% | +23.0% | — | +98.0% |
| Operating MarginEBIT ÷ Revenue | +0.2% | -18.6% | -22.2% | -102.9% |
| Net MarginNet income ÷ Revenue | -16.6% | -39.1% | -20.5% | -112.0% |
| FCF MarginFCF ÷ Revenue | +11.5% | -12.0% | -13.2% | -128.2% |
| Rev. Growth (YoY)Latest quarter vs prior year | -16.4% | +2.1% | -26.4% | +2.2% |
| EPS Growth (YoY)Latest quarter vs prior year | -37.3% | -11.7% | +38.6% | +100.0% |
Valuation Metrics
BIOX leads this category, winning 2 of 3 comparable metrics.
Valuation Metrics
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $30M | $1.2B | $280M | $1.8B |
| Enterprise ValueMkt cap + debt − cash | $274M | $1.2B | $312M | $2.0B |
| Trailing P/EPrice ÷ TTM EPS | -0.58x | -8.83x | -2.11x | -6.24x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — |
| EV / EBITDAEnterprise value multiple | 20.01x | — | — | — |
| Price / SalesMarket cap ÷ Revenue | 0.09x | 309.66x | 42.18x | 10.51x |
| Price / BookPrice ÷ Book value/share | 0.10x | 28.85x | 1.39x | 27.53x |
| Price / FCFMarket cap ÷ FCF | 0.85x | — | — | — |
Profitability & Efficiency
BIOX leads this category, winning 6 of 9 comparable metrics.
Profitability & Efficiency
BIOX delivers a -16.7% return on equity — every $100 of shareholder capital generates $-17 in annual profit, vs $-6 for PGEN. PGEN carries lower financial leverage with a 0.14x debt-to-equity ratio, signaling a more conservative balance sheet compared to SNDX's 5.36x. On the Piotroski fundamental quality scale (0–9), BIOX scores 3/9 vs SNDX's 2/9, reflecting mixed financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -16.7% | -5.9% | -65.8% | -2.6% |
| ROA (TTM)Return on assets | -6.7% | -144.1% | -42.7% | -45.2% |
| ROICReturn on invested capital | -0.5% | -152.8% | -36.5% | -54.2% |
| ROCEReturn on capital employed | -0.8% | -107.2% | -43.1% | -53.0% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 3 | 2 | 2 |
| Debt / EquityFinancial leverage | 0.94x | 0.14x | 0.38x | 5.36x |
| Net DebtTotal debt minus cash | $244M | -$24M | $31M | $212M |
| Cash & Equiv.Liquid assets | $33M | $30M | $47M | $135M |
| Total DebtShort + long-term debt | $277M | $6M | $78M | $346M |
| Interest CoverageEBIT ÷ Interest expense | -0.07x | -273.83x | — | -2.31x |
Total Returns (Dividends Reinvested)
PGEN leads this category, winning 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in SNDX five years ago would be worth $12,805 today (with dividends reinvested), compared to $317 for BIOX. Over the past 12 months, PGEN leads with a +207.4% total return vs BIOX's -88.5%. The 3-year compound annual growth rate (CAGR) favors PGEN at 49.2% vs BIOX's -64.0% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | -65.0% | -3.0% | +145.5% | -3.6% |
| 1-Year ReturnPast 12 months | -88.5% | +207.4% | +143.0% | +105.6% |
| 3-Year ReturnCumulative with dividends | -95.3% | +232.0% | -55.4% | +1.2% |
| 5-Year ReturnCumulative with dividends | -96.8% | -36.5% | -96.8% | +28.1% |
| 10-Year ReturnCumulative with dividends | -95.1% | -84.6% | +40.5% | +43.4% |
| CAGR (3Y)Annualised 3-year return | -64.0% | +49.2% | -23.6% | +0.4% |
Risk & Volatility
Evenly matched — FATE and SNDX each lead in 1 of 2 comparable metrics.
Risk & Volatility
SNDX is the less volatile stock with a 0.81 beta — it tends to amplify market swings less than FATE's 2.17 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. FATE currently trades 98.6% from its 52-week high vs BIOX's 9.1% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.94x | 1.44x | 2.17x | 0.81x |
| 52-Week HighHighest price in past year | $5.18 | $5.23 | $2.46 | $25.58 |
| 52-Week LowLowest price in past year | $0.35 | $1.23 | $0.91 | $8.58 |
| % of 52W HighCurrent price vs 52-week peak | +9.1% | +79.3% | +98.6% | +80.3% |
| RSI (14)Momentum oscillator 0–100 | 44.6 | 62.7 | 81.0 | 41.3 |
| Avg Volume (50D)Average daily shares traded | 804K | 4.3M | 1.9M | 1.5M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: PGEN as "Buy", FATE as "Buy", SNDX as "Buy". Consensus price targets imply 1525.5% upside for FATE (target: $40) vs 44.6% for PGEN (target: $6).
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | — | $6.00 | $39.50 | $40.00 |
| # AnalystsCovering analysts | — | 16 | 31 | 22 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | — | — | 1 |
| Dividend / ShareAnnual DPS | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | +3.1% | 0.0% | 0.0% | 0.0% |
BIOX leads in 2 of 6 categories (Valuation Metrics, Profitability & Efficiency). PGEN leads in 1 (Total Returns). 2 tied.
BIOX vs PGEN vs FATE vs SNDX: Key Questions Answered
8 questions · data-driven answers · updated daily
01Is BIOX or PGEN or FATE or SNDX a better buy right now?
For growth investors, Syndax Pharmaceuticals, Inc.
(SNDX) is the stronger pick with 627. 8% revenue growth year-over-year, versus -51. 2% for Fate Therapeutics, Inc. (FATE). Analysts rate Precigen, Inc. (PGEN) a "Buy" — based on 16 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — BIOX or PGEN or FATE or SNDX?
Over the past 5 years, Syndax Pharmaceuticals, Inc.
(SNDX) delivered a total return of +28. 1%, compared to -96. 8% for Bioceres Crop Solutions Corp. (BIOX). Over 10 years, the gap is even starker: SNDX returned +43. 4% versus BIOX's -95. 1%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — BIOX or PGEN or FATE or SNDX?
By beta (market sensitivity over 5 years), Syndax Pharmaceuticals, Inc.
(SNDX) is the lower-risk stock at 0. 81β versus Fate Therapeutics, Inc. 's 2. 17β — meaning FATE is approximately 169% more volatile than SNDX relative to the S&P 500. On balance sheet safety, Precigen, Inc. (PGEN) carries a lower debt/equity ratio of 14% versus 5% for Syndax Pharmaceuticals, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — BIOX or PGEN or FATE or SNDX?
By revenue growth (latest reported year), Syndax Pharmaceuticals, Inc.
(SNDX) is pulling ahead at 627. 8% versus -51. 2% for Fate Therapeutics, Inc. (FATE). On earnings-per-share growth, the picture is similar: Fate Therapeutics, Inc. grew EPS 29. 9% year-over-year, compared to -1704. 7% for Bioceres Crop Solutions Corp.. Over a 3-year CAGR, BIOX leads at 0. 5% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — BIOX or PGEN or FATE or SNDX?
Bioceres Crop Solutions Corp.
(BIOX) is the more profitable company, earning -15. 5% net margin versus -32. 2% for Precigen, Inc. — meaning it keeps -15. 5% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: BIOX leads at -1. 1% versus -34. 4% for PGEN. At the gross margin level — before operating expenses — SNDX leads at 96. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — BIOX or PGEN or FATE or SNDX?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is BIOX or PGEN or FATE or SNDX better for a retirement portfolio?
For long-horizon retirement investors, Syndax Pharmaceuticals, Inc.
(SNDX) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 81)). Bioceres Crop Solutions Corp. (BIOX) carries a higher beta of 1. 94 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (SNDX: +43. 4%, BIOX: -95. 1%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between BIOX and PGEN and FATE and SNDX?
These companies operate in different sectors (BIOX (Basic Materials) and PGEN (Healthcare) and FATE (Healthcare) and SNDX (Healthcare)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.
In terms of investment character: BIOX is a small-cap quality compounder stock; PGEN is a small-cap quality compounder stock; FATE is a small-cap quality compounder stock; SNDX is a small-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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