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SNDXSyndax Pharmaceuticals, Inc.
$17.64$1.6B
Overview & Tools
OverviewChart Terminal ↗Visualize
Valuation & Forecasts
Valuation ModelsEstimatesDCF Model
Price & Analyst Data
Analyst TargetsPrice History
Financial Statements
Income StatementBalance SheetCash FlowRatios & Margins
Performance
P/E HistoryRevenue HistoryEarnings HistoryDividend HistoryTotal Return
Discovery & Screens
Live BreakoutsStock ScreenerOwnership
SNDX logo

Syndax Pharmaceuticals, Inc.

SNDX
NASDAQ · Biotechnology
$17.64
At close - Sep 23, 4:00 PM EDT - USD
Market Cap$1.56B
P/E-5.4x
52W High$25.59
Volume2.08M
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q2

Milestone Revenue Surge Masks Persistent Cash Burn

Syndax Pharmaceuticals is transitioning from a clinical-stage to a pre-commercial entity, evidenced by a 627.8% year-over-year revenue surge to $172.4M in the trailing twelve months, driven largely by a $72.8M milestone payment from the Incyte collaboration. H...

GrowthAccelerating
ProfitabilityNegative
ValuationReview
TechnicalsWeak
Explore valuation models
MARKET ACTION

SNDX price & volume

Price trend, volume and key moving averages

Launch Terminal
Loading chart...
Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

8/12 Beats

EPS beat 8 of last 12 quarters

02

Valuation risk

-126% Peers

P/E is 126% below peer median

03

Market leadership

RS 20 · Lag

Laggard (Underperforming 80% of market)

04

Weak Trend

Below 200DMA

Price < 200DMA

Next CatalystEstimated earnings · Nov 4

Market performance

Price History →

Trailing total returns as of 9/24/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
SNDX-17.18%
S&P 500 (^GSPC)+12.39%
1-Year Return
SNDX+18.79%
S&P 500 (^GSPC)+15.77%
3-Year Return
SNDX+12.29%
S&P 500 (^GSPC)+75.41%
5-Year Return
SNDX-5.47%
S&P 500 (^GSPC)+69.91%
02

Test the fundamentals

Check whether operating performance supports the current valuation.

VALUATION & INTRINSIC VALUE

Valuation Scenarios

Valuation Analysis
Trailing P/E5Y Low
-5.4x
Forward P/E
N/A
EV/EBITDA
N/A
FCF YieldCash Flow
N/A

Valuation vs 5-Year History

Multiple Range
Metric
Current
5Y Median
Historical Range
Percentile
P/E
-5.4x
45.6x
0th· Low
EV/EBITDA
N/A
35.7x
N/A
Price/FCF
N/A
39.3x
N/A
Current Multiple
5Y Median (50th %ile)

Intrinsic Value Scenarios

DCF Projection
No DCF Model AvailableIntrinsic value modeling is not supported for this equity.

Growth & profitability

Annual revenue & EPS trend
Revenue
$172M+627.8% YoY
Net income
-$285M+10.5% YoY
Free cash flow
-$323M-17.6% YoY
Operating margin
-158.4%+1276.0 pts YoY
ROIC (TTM)-54.2%
Avg ROIC 5Y-
ROE (TTM)-161.8%
Piotroski Score2 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate8/12 (67%)
Revenue Beat Rate2/12 (25%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q3 2026Latest
Aug 4, 2026
-$0.55-22.9%
vs -$0.45
$73M-8.3%
vs $79M
Q2 2026
Apr 30, 2026
-$0.48+18.6%
vs -$0.59
$65M-7.0%
vs $70M
Q1 2026
Feb 26, 2026
-$0.78-33.6%
vs -$0.58
$69M+6.9%
vs $64M
Q4 2025
Nov 3, 2025
-$0.70+5.4%
vs -$0.74
$46M-27.6%
vs $63M
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

5 Stories
Seeking Alpha·Sep 10, 2026
Syndax Pharmaceuticals, Inc. (SNDX) Presents at Citigroup's Biopharma Back to School Summit 2026 Transcript

Syndax Pharmaceuticals, Inc. (SNDX) Presents at Citigroup's Biopharma Back to School Summit 2026 Transcript

GlobeNewsWire·Sep 4, 2026
Syndax Pharmaceuticals Reports Inducement Grants Under NASDAQ Listing Rule 5635(c)(4)

NEW YORK, Sept. 04, 2026 (GLOBE NEWSWIRE) -- Syndax Pharmaceuticals (Nasdaq: SNDX), a commercial-stage biopharmaceutical company advancing innovative cancer therapies, today announced that on September 1, 2026, the Company granted inducement awards to purchase up to 175,000 shares of common stock to nineteen new employees under the Company's 2023 Inducement Plan. The stock options will vest over four years, with 25% of the underlying shares vesting on the one-year anniversary of the vesting commencement date and 1/48th of the underlying shares vesting monthly thereafter over 36 months, subject to the employee's continued service relationship with Syndax through the applicable vesting dates.

GlobeNewsWire·Sep 1, 2026
Syndax Announces Participation in September Investor Conferences

NEW YORK, Sept. 01, 2026 (GLOBE NEWSWIRE) -- Syndax Pharmaceuticals (Nasdaq: SNDX), a commercial-stage biopharmaceutical company advancing innovative cancer therapies, today announced that Michael A.

Defense World·Aug 28, 2026
BlackRock Inc. Makes New Investment in Syndax Pharmaceuticals, Inc. $SNDX

BlackRock Inc. bought a new position in Syndax Pharmaceuticals, Inc. (NASDAQ: SNDX) in the undefined quarter, according to its most recent disclosure with the SEC. The firm bought 9,020,006 shares of the company's stock, valued at approximately $197,177,000. BlackRock Inc. owned 10.18% of Syndax Pharmaceuticals at the end of the most recent quarter.

Filtered for Syndax Pharmaceuticals, Inc.More Headlines
04

Compare before deciding

Benchmark SNDX against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Syndax Pharmaceuticals, Inc. (SNDX)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
SNDX logoSNDXSyndax Pharmaceuticals, Inc.Current
$17.64$1.56B-5.36627.84%-165.6%-161.82%—
KYMR logoKYMRKymera Therapeutics, Inc.
$115.47$9.5B-31.29-16.72%-285.41%-21.5%—
IMVT logoIMVTImmunovant, Inc.
$34.54$7.13B-12.47—-7585.86%-69.59%—
RVMD logoRVMDRevolution Medicines, Inc.
$190.74$40.55B-32.06——-96.44%—
TGTX logoTGTXTG Therapeutics, Inc.
$56.00$8.57B20.2287.32%55.22%72.3%—
PRAX logoPRAXPraxis Precision Medicines, Inc.
$282.12$7.87B-20.93-100%—-34.15%—

Compare SNDX vs Peers

Syndax Pharmaceuticals, Inc. (SNDX) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs KYMR

Most directly comparable listed peer for SNDX.

Scale Benchmark

vs ABBV

Larger-name benchmark to compare SNDX against a more recognizable public peer.

Peer Set

Compare Top 5

vs KYMR, IMVT, RVMD, TGTX

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

SNDX SEC Filings & Documents

Syndax Pharmaceuticals, Inc. (SNDX) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Aug 4, 2026·SEC

Material company update

Jul 14, 2026·SEC

Material company update

Jun 10, 2026·SEC

10-K Annual Reports

3
FY 2026

Feb 26, 2026·SEC

FY 2025

Mar 3, 2025·SEC

FY 2024

Feb 27, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

Aug 4, 2026·SEC

FY 2026

Apr 30, 2026·SEC

FY 2025

Nov 3, 2025·SEC

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SNDX Frequently Asked Questions

Syndax Pharmaceuticals, Inc. (SNDX) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Syndax Pharmaceuticals, Inc.'s revenue?

Syndax Pharmaceuticals, Inc. (SNDX) reported $252.0M in revenue for fiscal year 2025.

How fast is Syndax Pharmaceuticals, Inc. growing?

Syndax Pharmaceuticals, Inc. (SNDX) grew revenue by 627.8% over the past year. This is strong growth.

Is SNDX profitable?

Syndax Pharmaceuticals, Inc. (SNDX) reported a net loss of $220.8M for fiscal year 2025.

Dividend & Returns
What is SNDX's return on equity?

Syndax Pharmaceuticals, Inc. (SNDX) has a return on equity (ROE) of -161.8%. Negative ROE indicates the company is unprofitable.

What is Syndax Pharmaceuticals, Inc.'s free cash flow?

Syndax Pharmaceuticals, Inc. (SNDX) had negative free cash flow of $220.9M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in SNDX back in 2011?

Total return calculator · dividends reinvested · 15+ years of data

See returns →