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SNDX
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SNDXSyndax Pharmaceuticals, Inc.
$9.54$845M
Overview & Tools
OverviewChart Terminal ↗Visualize
Valuation & Forecasts
Valuation ModelsEstimatesDCF Model
Price & Analyst Data
Analyst TargetsPrice History
Financial Statements
Income StatementBalance SheetCash FlowRatios & Margins
Performance
P/E HistoryRevenue HistoryEarnings HistoryDividend HistoryTotal Return
Discovery & Screens
Live BreakoutsStock ScreenerOwnership
SNDX logo

Syndax Pharmaceuticals, Inc.

SNDX
NASDAQ · Oncology Biotech
$9.54
At close - Nov 6, 4:00 PM EST - USD
Market Cap$845M
P/E-4.1x
52W High$25.59
Volume4.17M
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q3

Milestone Revenue Surge Masks Persistent Operating Cash Burn

SNDX's quarterly revenue scaled from $3.5M in 2024Q2 to $83.3M in 2026Q3, but the pattern of lumpy jumps suggests milestone recognition rather than recurring commercial demand, and operating losses of roughly $34M to $42M per quarter persist.

GrowthAccelerating
ProfitabilityWeak
ValuationReview
TechnicalsWeak
Explore valuation models
MARKET ACTION

SNDX price & volume

Price trend, volume and key moving averages

Launch Terminal
Loading chart...
Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

7/12 Beats

EPS beat 7 of last 12 quarters

02

Valuation risk

-112% Peers

P/E is 112% below peer median

03

Market leadership

RS 10 · Lag

Laggard (Underperforming 90% of market)

04

Weak Trend

Below 200DMA

Price < 200DMA

Next CatalystEstimated earnings · Feb 2

Market performance

Price History →

Trailing total returns as of 11/8/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
SNDX-55.21%
S&P 500 (^GSPC)+7.63%
1-Year Return
SNDX-35.06%
S&P 500 (^GSPC)+9.69%
3-Year Return
SNDX-33.75%
S&P 500 (^GSPC)+70.99%
5-Year Return
SNDX-45.49%
S&P 500 (^GSPC)+59.09%
02

Test the fundamentals

Check whether operating performance supports the current valuation.

VALUATION & INTRINSIC VALUE

Valuation Scenarios

Valuation Analysis
Trailing P/E5Y Low
-4.1x
Forward P/E
N/A
EV/EBITDA
N/A
FCF YieldCash Flow
N/A

Valuation vs 5-Year History

Multiple Range
Metric
Current
5Y Median
Historical Range
Percentile
P/E
-4.1x
45.6x
0th· Low
EV/EBITDA
N/A
35.7x
N/A
Price/FCF
N/A
39.3x
N/A
Current Multiple
5Y Median (50th %ile)

Intrinsic Value Scenarios

DCF Projection
No DCF Model AvailableIntrinsic value modeling is not supported for this equity.

Growth & profitability

Annual revenue & EPS trend
Revenue FY25
$172M+627.8% YoY
Net income FY25
-$285M+10.5% YoY
Free cash flow FY25
-$323M-17.6% YoY
Operating margin FY25
-158.4%+1276.0 pts YoY
ROIC (FY25)-54.2%
Avg ROIC 5Y-40.6%
ROE (TTM)-804.4%
Piotroski Score2 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate7/12 (58%)
Revenue Beat Rate3/12 (33%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q4 2026Latest
Nov 2, 2026
-$0.55-9.1%
vs -$0.50
$83M+2.4%
vs $81M
Q3 2026
Aug 4, 2026
-$0.55-22.9%
vs -$0.45
$73M-8.3%
vs $79M
Q2 2026
Apr 30, 2026
-$0.48+18.6%
vs -$0.59
$65M-7.0%
vs $70M
Q1 2026
Feb 26, 2026
-$0.78-33.6%
vs -$0.58
$69M+6.9%
vs $64M
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

4 Stories
GlobeNewsWire·3d ago
Syndax Pharmaceuticals Reports Inducement Grants Under NASDAQ Listing Rule 5635(c)(4)

NEW YORK, Nov. 04, 2026 (GLOBE NEWSWIRE) -- Syndax Pharmaceuticals (Nasdaq: SNDX), a commercial-stage biopharmaceutical company advancing innovative cancer therapies, today announced that on November 4, 2026, the Company granted inducement awards to purchase up to 213,500 shares of common stock to five new employees under the Company's 2023 Inducement Plan. The stock options will vest over four years, with 25% of the underlying shares vesting on the one-year anniversary of the vesting commencement date and 1/48th of the underlying shares vesting monthly thereafter over 36 months, subject to the employee's continued service relationship with Syndax through the applicable vesting dates.

Seeking Alpha·4d ago
Syndax Pharmaceuticals: Revuforj Shows Strong Commercial Growth, But Frontline AML Is The Key

Syndax Pharmaceuticals remains on track, with Revuforj driving robust commercial growth and Niktimvo providing a secondary revenue stream. 3Q26 revenue surged 82% YoY to $83.3M, led by Revuforj's 90% YoY growth; operating losses narrowed despite rising R&D spend. Post-transplant maintenance trends could extend Revuforj treatment duration, offering upside if patient resumption rates increase, as management anticipates.

GlobeNewsWire·4d ago
Syndax to Host ASH Investor Event in Person and via Webcast on December 14, 2026

NEW YORK, Nov. 04, 2026 (GLOBE NEWSWIRE) -- Syndax Pharmaceuticals (Nasdaq: SNDX), a commercial-stage biopharmaceutical company advancing innovative cancer therapies, today announced that the Company will host an in-person investor event, along with a live webcast, on Monday, December 14, 2026, from 7:00–8:30 a.m. CT / 8:00–9:30 a.m.

GlobeNewsWire·4d ago
Syndax Highlights Acceptance of 19 Revuforj® (revumenib) and Niktimvo™ (axatilimab-csfr) Abstracts, Including 7 for Oral Presentation, at ASH 2026

– 14 accepted revumenib abstracts, including 7 for oral presentation, reinforce Syndax's scientific leadership in menin inhibition – – Revumenib abstracts highlight encouraging activity across multiple acute leukemia subtypes and settings, including frontline, post-transplant maintenance, and MRD relapse – – Real-world data showcase compelling results in R/R NPM1m or KMT2Ar acute leukemia patients who received revumenib monotherapy or combination therapy –  – 5 accepted axatilimab abstracts, including long-term data that highlight the potential for prolonged clinical benefit with axatilimab in R/R cGVHD – – Company to host investor event and webcast on Monday, December 14, 2026, at 7:00 a.m. CT/8:00 a.m.

Filtered for Syndax Pharmaceuticals, Inc.More Headlines
04

Compare before deciding

Benchmark SNDX against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Syndax Pharmaceuticals, Inc. (SNDX)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
SNDX logoSNDXSyndax Pharmaceuticals, Inc.Current
$9.54$845.34M-4.09627.84%-72.38%-804.38%—
KYMR logoKYMRKymera Therapeutics, Inc.
$131.73$10.84B-37.73-16.72%-341.87%-22.39%—
IMVT logoIMVTImmunovant, Inc.
$30.53$6.3B-11.66—-7585.86%-69.59%—
RVMD logoRVMDRevolution Medicines, Inc.
$192.28$40.88B-22.10—-946.82%-91.93%—
TGTX logoTGTXTG Therapeutics, Inc.
$59.83$9.16B21.3187.32%55.22%72.3%—
PRAX logoPRAXPraxis Precision Medicines, Inc.
$277.62$7.74B-23.85-100%—-34.15%—

Compare SNDX vs Peers

Syndax Pharmaceuticals, Inc. (SNDX) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs KYMR

Most directly comparable listed peer for SNDX.

Scale Benchmark

vs ABBV

Larger-name benchmark to compare SNDX against a more recognizable public peer.

Peer Set

Compare Top 5

vs KYMR, IMVT, RVMD, TGTX

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

SNDX SEC Filings & Documents

Syndax Pharmaceuticals, Inc. (SNDX) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Nov 2, 2026·SEC

Material company update

Aug 4, 2026·SEC

Material company update

Jul 14, 2026·SEC

10-K Annual Reports

3
FY 2026

Feb 26, 2026·SEC

FY 2025

Mar 3, 2025·SEC

FY 2024

Feb 27, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

Nov 2, 2026·SEC

FY 2026

Aug 4, 2026·SEC

FY 2026

Apr 30, 2026·SEC

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SNDX Frequently Asked Questions

Syndax Pharmaceuticals, Inc. (SNDX) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Syndax Pharmaceuticals, Inc.'s revenue?

Syndax Pharmaceuticals, Inc. (SNDX) reported $289.4M in revenue over the trailing twelve months. Revenue was $172.4M in fiscal year 2025.

How fast is Syndax Pharmaceuticals, Inc. growing?

Syndax Pharmaceuticals, Inc. (SNDX) grew revenue by 159.5% over the trailing twelve months, compared with the twelve months before.

Is SNDX profitable?

No. Syndax Pharmaceuticals, Inc. (SNDX) reported a net loss of $209.5M over the trailing twelve months.

Dividend & Returns
What is SNDX's return on equity?

Syndax Pharmaceuticals, Inc. (SNDX) had a return on equity (ROE) of -804.4% over the trailing twelve months. A negative ROE means the company lost money over the period.

What is Syndax Pharmaceuticals, Inc.'s free cash flow?

Syndax Pharmaceuticals, Inc. (SNDX) had negative free cash flow of $177.5M over the trailing twelve months.

What if you invested $1,000 in SNDX back in 2011?

Total return calculator · dividends reinvested · 15+ years of data

See returns →