Biotechnology
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5 / 10Stock Comparison
BLTE vs DBVT vs REGN vs ABBV vs MRK
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Drug Manufacturers - General
Drug Manufacturers - General
BLTE vs DBVT vs REGN vs ABBV vs MRK — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Drug Manufacturers - General | Drug Manufacturers - General |
| Market Cap | $4.96B | $1712.35T | $73.68B | $358.42B | $277.34B |
| Revenue (TTM) | $0.00 | $0.00 | $14.92B | $61.16B | $64.93B |
| Net Income (TTM) | $-49M | $-168M | $4.42B | $4.23B | $18.25B |
| Gross Margin | — | — | 84.5% | 70.2% | 74.2% |
| Operating Margin | — | — | 24.3% | 26.7% | 41.1% |
| Forward P/E | — | — | 15.3x | 14.3x | 21.9x |
| Total Debt | $537K | $22M | $2.71B | $69.07B | $50.53B |
| Cash & Equiv. | $32M | $194M | $3.12B | $5.23B | $14.56B |
BLTE vs DBVT vs REGN vs ABBV vs MRK — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Apr 22 | May 26 | Return |
|---|---|---|---|
| Belite Bio, Inc (BLTE) | 100 | 1473.1 | +1373.1% |
| DBV Technologies S.… (DBVT) | 100 | 155.0 | +55.0% |
| Regeneron Pharmaceu… (REGN) | 100 | 107.6 | +7.6% |
| AbbVie Inc. (ABBV) | 100 | 138.0 | +38.0% |
| Merck & Co., Inc. (MRK) | 100 | 126.6 | +26.6% |
Price return only. Dividends and distributions are not included.
Quick Verdict: BLTE vs DBVT vs REGN vs ABBV vs MRK
Each card shows where this stock fits in a portfolio — not just who wins on paper.
BLTE is the #2 pick in this set and the best alternative if long-term compounding and sleep-well-at-night is your priority.
- 13.7% 10Y total return vs ABBV's 295.5%
- Lower volatility, beta 0.80, Low D/E 0.4%, current ratio 24.31x
- +154.4% vs ABBV's +11.3%
Among these 5 stocks, DBVT doesn't own a clear edge in any measured category.
REGN ranks third and is worth considering specifically for growth exposure.
- Rev growth 1.0%, EPS growth 8.2%, 3Y rev CAGR 5.6%
- 29.6% margin vs DBVT's 0.3%
ABBV carries the broadest edge in this set and is the clearest fit for income & stability and defensive.
- Dividend streak 13 yrs, beta 0.34, yield 3.2%
- Beta 0.34, yield 3.2%, current ratio 0.67x
- 8.6% revenue growth vs DBVT's -100.0%
- Better valuation composite
MRK is the clearest fit if your priority is valuation efficiency.
- PEG 1.03 vs REGN's 2.43
- 14.6% ROA vs DBVT's -89.0%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 8.6% revenue growth vs DBVT's -100.0% | |
| Value | Better valuation composite | |
| Quality / Margins | 29.6% margin vs DBVT's 0.3% | |
| Stability / Safety | Beta 0.34 vs DBVT's 1.26 | |
| Dividends | 3.2% yield, 13-year raise streak, vs MRK's 2.9%, (2 stocks pay no dividend) | |
| Momentum (1Y) | +154.4% vs ABBV's +11.3% | |
| Efficiency (ROA) | 14.6% ROA vs DBVT's -89.0% |
BLTE vs DBVT vs REGN vs ABBV vs MRK — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
BLTE vs DBVT vs REGN vs ABBV vs MRK — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
REGN leads in 1 of 6 categories
MRK leads 1 • ABBV leads 1 • BLTE leads 1 • DBVT leads 0 • 2 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
REGN leads this category, winning 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
MRK and DBVT operate at a comparable scale, with $64.9B and $0 in trailing revenue. REGN is the more profitable business, keeping 29.6% of every revenue dollar as net income compared to ABBV's 6.9%. On growth, REGN holds the edge at +19.0% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $0 | $14.9B | $61.2B | $64.9B |
| EBITDAEarnings before interest/tax | -$50M | -$112M | $4.2B | $24.5B | $32.4B |
| Net IncomeAfter-tax profit | -$49M | -$168M | $4.4B | $4.2B | $18.3B |
| Free Cash FlowCash after capex | $0 | -$151M | $4.2B | $18.7B | $12.4B |
| Gross MarginGross profit ÷ Revenue | — | — | +84.5% | +70.2% | +74.2% |
| Operating MarginEBIT ÷ Revenue | — | — | +24.3% | +26.7% | +41.1% |
| Net MarginNet income ÷ Revenue | — | — | +29.6% | +6.9% | +28.1% |
| FCF MarginFCF ÷ Revenue | — | — | +27.9% | +30.6% | +19.0% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | — | +19.0% | +10.0% | +4.5% |
| EPS Growth (YoY)Latest quarter vs prior year | -61.3% | +91.5% | -7.2% | +57.4% | -19.6% |
Valuation Metrics
MRK leads this category, winning 3 of 7 comparable metrics.
Valuation Metrics
At 15.4x trailing earnings, MRK trades at a 82% valuation discount to ABBV's 85.5x P/E. Adjusting for growth (PEG ratio), MRK offers better value at 0.73x vs REGN's 2.70x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $5.0B | $1712.35T | $73.7B | $358.4B | $277.3B |
| Enterprise ValueMkt cap + debt − cash | $4.9B | $1712.35T | $73.3B | $422.3B | $313.3B |
| Trailing P/EPrice ÷ TTM EPS | -132.20x | -0.76x | 17.09x | 85.50x | 15.42x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | 15.35x | 14.28x | 21.93x |
| PEG RatioP/E ÷ EPS growth rate | — | — | 2.70x | — | 0.73x |
| EV / EBITDAEnterprise value multiple | — | — | 17.78x | 14.96x | 10.68x |
| Price / SalesMarket cap ÷ Revenue | — | — | 5.14x | 5.86x | 4.27x |
| Price / BookPrice ÷ Book value/share | 32.67x | 0.66x | 2.46x | — | 5.35x |
| Price / FCFMarket cap ÷ FCF | — | — | 18.06x | 20.12x | 22.44x |
Profitability & Efficiency
ABBV leads this category, winning 3 of 9 comparable metrics.
Profitability & Efficiency
ABBV delivers a 62.1% return on equity — every $100 of shareholder capital generates $62 in annual profit, vs $-130 for DBVT. BLTE carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to MRK's 0.96x. On the Piotroski fundamental quality scale (0–9), ABBV scores 6/9 vs BLTE's 3/9, reflecting solid financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -34.9% | -130.2% | +14.3% | +62.1% | +36.1% |
| ROA (TTM)Return on assets | -33.6% | -89.0% | +11.1% | +3.1% | +14.6% |
| ROICReturn on invested capital | -50.9% | — | +8.9% | +23.9% | +22.0% |
| ROCEReturn on capital employed | -33.7% | -145.7% | +10.2% | +21.5% | +23.8% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 4 | 5 | 6 | 4 |
| Debt / EquityFinancial leverage | 0.00x | 0.13x | 0.09x | — | 0.96x |
| Net DebtTotal debt minus cash | -$31M | -$172M | -$412M | $63.8B | $36.0B |
| Cash & Equiv.Liquid assets | $32M | $194M | $3.1B | $5.2B | $14.6B |
| Total DebtShort + long-term debt | $537,000 | $22M | $2.7B | $69.1B | $50.5B |
| Interest CoverageEBIT ÷ Interest expense | -1999.80x | -189.82x | 108.44x | 3.28x | 19.68x |
Total Returns (Dividends Reinvested)
BLTE leads this category, winning 5 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in BLTE five years ago would be worth $147,309 today (with dividends reinvested), compared to $3,090 for DBVT. Over the past 12 months, BLTE leads with a +154.4% total return vs ABBV's +11.3%. The 3-year compound annual growth rate (CAGR) favors BLTE at 79.9% vs REGN's -1.7% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -2.1% | +4.9% | -8.5% | -10.1% | +6.3% |
| 1-Year ReturnPast 12 months | +154.4% | +110.4% | +27.1% | +11.3% | +46.1% |
| 3-Year ReturnCumulative with dividends | +482.1% | +19.7% | -5.1% | +50.4% | +2.9% |
| 5-Year ReturnCumulative with dividends | +1373.1% | -69.1% | +43.6% | +101.3% | +70.2% |
| 10-Year ReturnCumulative with dividends | +1373.1% | -87.0% | +90.0% | +295.5% | +166.5% |
| CAGR (3Y)Annualised 3-year return | +79.9% | +6.2% | -1.7% | +14.6% | +0.9% |
Risk & Volatility
Evenly matched — ABBV and MRK each lead in 1 of 2 comparable metrics.
Risk & Volatility
ABBV is the less volatile stock with a 0.34 beta — it tends to amplify market swings less than DBVT's 1.26 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. MRK currently trades 89.7% from its 52-week high vs DBVT's 76.3% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.80x | 1.26x | 0.81x | 0.34x | 0.48x |
| 52-Week HighHighest price in past year | $200.00 | $26.18 | $821.11 | $244.81 | $125.14 |
| 52-Week LowLowest price in past year | $56.10 | $7.53 | $476.49 | $176.57 | $73.31 |
| % of 52W HighCurrent price vs 52-week peak | +78.0% | +76.3% | +86.4% | +82.8% | +89.7% |
| RSI (14)Momentum oscillator 0–100 | 43.0 | 48.1 | 44.9 | 46.8 | 46.7 |
| Avg Volume (50D)Average daily shares traded | 155K | 252K | 631K | 5.8M | 7.3M |
Analyst Outlook
Evenly matched — ABBV and MRK each lead in 1 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: BLTE as "Buy", DBVT as "Buy", REGN as "Buy", ABBV as "Buy", MRK as "Buy". Consensus price targets imply 131.8% upside for DBVT (target: $46) vs 15.2% for MRK (target: $129). For income investors, ABBV offers the higher dividend yield at 3.24% vs REGN's 0.48%.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $203.00 | $46.33 | $865.68 | $256.64 | $129.31 |
| # AnalystsCovering analysts | 6 | 15 | 48 | 41 | 37 |
| Dividend YieldAnnual dividend ÷ price | — | — | +0.5% | +3.2% | +2.9% |
| Dividend StreakConsecutive years of raises | — | 0 | 1 | 13 | 14 |
| Dividend / ShareAnnual DPS | — | — | $3.41 | $6.57 | $3.26 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | +5.4% | +0.3% | +1.8% |
REGN leads in 1 of 6 categories (Income & Cash Flow). MRK leads in 1 (Valuation Metrics). 2 tied.
BLTE vs DBVT vs REGN vs ABBV vs MRK: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is BLTE or DBVT or REGN or ABBV or MRK a better buy right now?
For growth investors, AbbVie Inc.
(ABBV) is the stronger pick with 8. 6% revenue growth year-over-year, versus 1. 0% for Regeneron Pharmaceuticals, Inc. (REGN). Merck & Co. , Inc. (MRK) offers the better valuation at 15. 4x trailing P/E (21. 9x forward), making it the more compelling value choice. Analysts rate Belite Bio, Inc (BLTE) a "Buy" — based on 6 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — BLTE or DBVT or REGN or ABBV or MRK?
On trailing P/E, Merck & Co.
, Inc. (MRK) is the cheapest at 15. 4x versus AbbVie Inc. at 85. 5x. On forward P/E, AbbVie Inc. is actually cheaper at 14. 3x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Merck & Co. , Inc. wins at 1. 03x versus Regeneron Pharmaceuticals, Inc. 's 2. 43x — a reasonable growth-adjusted valuation.
03Which is the better long-term investment — BLTE or DBVT or REGN or ABBV or MRK?
Over the past 5 years, Belite Bio, Inc (BLTE) delivered a total return of +1373%, compared to -69.
1% for DBV Technologies S. A. (DBVT). Over 10 years, the gap is even starker: BLTE returned +1373% versus DBVT's -87. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — BLTE or DBVT or REGN or ABBV or MRK?
By beta (market sensitivity over 5 years), AbbVie Inc.
(ABBV) is the lower-risk stock at 0. 34β versus DBV Technologies S. A. 's 1. 26β — meaning DBVT is approximately 272% more volatile than ABBV relative to the S&P 500. On balance sheet safety, Belite Bio, Inc (BLTE) carries a lower debt/equity ratio of 0% versus 96% for Merck & Co. , Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — BLTE or DBVT or REGN or ABBV or MRK?
By revenue growth (latest reported year), AbbVie Inc.
(ABBV) is pulling ahead at 8. 6% versus 1. 0% for Regeneron Pharmaceuticals, Inc. (REGN). On earnings-per-share growth, the picture is similar: Regeneron Pharmaceuticals, Inc. grew EPS 8. 2% year-over-year, compared to -347. 5% for DBV Technologies S. A.. Over a 3-year CAGR, REGN leads at 5. 6% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — BLTE or DBVT or REGN or ABBV or MRK?
Regeneron Pharmaceuticals, Inc.
(REGN) is the more profitable company, earning 31. 4% net margin versus 0. 0% for DBV Technologies S. A. — meaning it keeps 31. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: MRK leads at 36. 2% versus 0. 0% for DBVT. At the gross margin level — before operating expenses — REGN leads at 85. 4%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is BLTE or DBVT or REGN or ABBV or MRK more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, Merck & Co. , Inc. (MRK) is the more undervalued stock at a PEG of 1. 03x versus Regeneron Pharmaceuticals, Inc. 's 2. 43x. A PEG below 1. 5 suggests fair-to-attractive pricing relative to expected growth. On forward earnings alone, AbbVie Inc. (ABBV) trades at 14. 3x forward P/E versus 21. 9x for Merck & Co. , Inc. — 7. 7x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for DBVT: 131. 8% to $46. 33.
08Which pays a better dividend — BLTE or DBVT or REGN or ABBV or MRK?
In this comparison, ABBV (3.
2% yield), MRK (2. 9% yield), REGN (0. 5% yield) pay a dividend. BLTE, DBVT do not pay a meaningful dividend and should not be held primarily for income.
09Is BLTE or DBVT or REGN or ABBV or MRK better for a retirement portfolio?
For long-horizon retirement investors, AbbVie Inc.
(ABBV) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 34), 3. 2% yield, +295. 5% 10Y return). Both have compounded well over 10 years (ABBV: +295. 5%, DBVT: -87. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between BLTE and DBVT and REGN and ABBV and MRK?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: BLTE is a small-cap quality compounder stock; DBVT is a mega-cap quality compounder stock; REGN is a mid-cap deep-value stock; ABBV is a large-cap income-oriented stock; MRK is a large-cap deep-value stock. ABBV, MRK pay a dividend while BLTE, DBVT, REGN do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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