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Stock Comparison

BRTX vs RGEN

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
BRTX
BioRestorative Therapies, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$2M
5Y Perf.-43.8%
RGEN
Repligen Corporation

Medical - Instruments & Supplies

HealthcareNASDAQ • US
Market Cap$7.13B
5Y Perf.-3.5%

BRTX vs RGEN — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
BRTX logoBRTX
RGEN logoRGEN
IndustryBiotechnologyMedical - Instruments & Supplies
Market Cap$2M$7.13B
Revenue (TTM)$383K$763M
Net Income (TTM)$-13M$51M
Gross Margin79.6%51.5%
Operating Margin-37.9%8.7%
Forward P/E64.3x
Total Debt$0.00$690M
Cash & Equiv.$548K$566M

BRTX vs RGENLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

BRTX
RGEN
StockMay 20May 26Return
BioRestorative Ther… (BRTX)10056.3-43.8%
Repligen Corporation (RGEN)10096.5-3.5%

Price return only. Dividends and distributions are not included.

Quick Verdict: BRTX vs RGEN

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: RGEN leads in 4 of 6 categories, making it the strongest pick for profitability and margin quality and capital preservation and lower volatility. BioRestorative Therapies, Inc. is the stronger pick specifically for growth and revenue expansion. As sector peers, any of these can serve as alternatives in the same allocation.
BRTX
BioRestorative Therapies, Inc.
The Growth Play

BRTX is the clearest fit if your priority is growth exposure.

  • Rev growth 175.0%, EPS growth 53.0%, 3Y rev CAGR 105.8%
  • 175.0% revenue growth vs RGEN's 16.4%
Best for: growth exposure
RGEN
Repligen Corporation
The Income Pick

RGEN carries the broadest edge in this set and is the clearest fit for income & stability and long-term compounding.

  • beta 1.76
  • 369.1% 10Y total return vs BRTX's -100.0%
  • Lower volatility, beta 1.76, Low D/E 32.8%, current ratio 8.37x
Best for: income & stability and long-term compounding
See the full category breakdown
CategoryWinnerWhy
GrowthBRTX logoBRTX175.0% revenue growth vs RGEN's 16.4%
Quality / MarginsRGEN logoRGEN6.7% margin vs BRTX's -33.0%
Stability / SafetyRGEN logoRGENBeta 1.76 vs BRTX's 2.21
DividendsTieNeither stock pays a meaningful dividend
Momentum (1Y)RGEN logoRGEN-0.4% vs BRTX's -87.5%
Efficiency (ROA)RGEN logoRGEN1.8% ROA vs BRTX's -224.5%, ROIC 2.2% vs -100.4%

BRTX vs RGEN — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

BRTXBioRestorative Therapies, Inc.
FY 2024
Product
74.8%$300,000
Royalty
25.2%$101,000
RGENRepligen Corporation
FY 2025
Product
50.0%$738M
Filtration Products
27.3%$403M
Chromatography Products
10.4%$153M
Proteins Products
6.6%$97M
Process Analytics Products
5.5%$81M
Other products
0.2%$3M

BRTX vs RGEN — Financial Metrics

Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLRGENLAGGINGBRTX

Income & Cash Flow (Last 12 Months)

RGEN leads this category, winning 5 of 6 comparable metrics.

RGEN is the larger business by revenue, generating $763M annually — 1991.0x BRTX's $383,400. RGEN is the more profitable business, keeping 6.7% of every revenue dollar as net income compared to BRTX's -33.0%. On growth, RGEN holds the edge at +14.8% YoY revenue growth, suggesting stronger near-term business momentum.

MetricBRTX logoBRTXBioRestorative Th…RGEN logoRGENRepligen Corporat…
RevenueTrailing 12 months$383,400$763M
EBITDAEarnings before interest/tax-$14M$155M
Net IncomeAfter-tax profit-$13M$51M
Free Cash FlowCash after capex-$11M$104M
Gross MarginGross profit ÷ Revenue+79.6%+51.5%
Operating MarginEBIT ÷ Revenue-37.9%+8.7%
Net MarginNet income ÷ Revenue-33.0%+6.7%
FCF MarginFCF ÷ Revenue-28.1%+13.7%
Rev. Growth (YoY)Latest quarter vs prior year-94.9%+14.8%
EPS Growth (YoY)Latest quarter vs prior year-153.8%+50.0%
RGEN leads this category, winning 5 of 6 comparable metrics.

Valuation Metrics

BRTX leads this category, winning 3 of 3 comparable metrics.
MetricBRTX logoBRTXBioRestorative Th…RGEN logoRGENRepligen Corporat…
Market CapShares × price$2M$7.1B
Enterprise ValueMkt cap + debt − cash$1M$7.3B
Trailing P/EPrice ÷ TTM EPS-0.19x147.01x
Forward P/EPrice ÷ next-FY EPS est.64.26x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple52.45x
Price / SalesMarket cap ÷ Revenue4.48x9.66x
Price / BookPrice ÷ Book value/share0.20x3.40x
Price / FCFMarket cap ÷ FCF75.94x
BRTX leads this category, winning 3 of 3 comparable metrics.

Profitability & Efficiency

RGEN leads this category, winning 5 of 7 comparable metrics.

RGEN delivers a 2.5% return on equity — every $100 of shareholder capital generates $2 in annual profit, vs $-6 for BRTX. On the Piotroski fundamental quality scale (0–9), RGEN scores 7/9 vs BRTX's 2/9, reflecting strong financial health.

MetricBRTX logoBRTXBioRestorative Th…RGEN logoRGENRepligen Corporat…
ROE (TTM)Return on equity-5.7%+2.5%
ROA (TTM)Return on assets-2.2%+1.8%
ROICReturn on invested capital-100.4%+2.2%
ROCEReturn on capital employed-124.7%+2.2%
Piotroski ScoreFundamental quality 0–927
Debt / EquityFinancial leverage0.33x
Net DebtTotal debt minus cash-$547,890$124M
Cash & Equiv.Liquid assets$547,890$566M
Total DebtShort + long-term debt$0$690M
Interest CoverageEBIT ÷ Interest expense2.64x
RGEN leads this category, winning 5 of 7 comparable metrics.

Total Returns (Dividends Reinvested)

RGEN leads this category, winning 6 of 6 comparable metrics.

A $10,000 investment in RGEN five years ago would be worth $6,732 today (with dividends reinvested), compared to $64 for BRTX. Over the past 12 months, RGEN leads with a -0.4% total return vs BRTX's -87.5%. The 3-year compound annual growth rate (CAGR) favors RGEN at -6.9% vs BRTX's -64.9% — a key indicator of consistent wealth creation.

MetricBRTX logoBRTXBioRestorative Th…RGEN logoRGENRepligen Corporat…
YTD ReturnYear-to-date-81.6%-23.1%
1-Year ReturnPast 12 months-87.5%-0.4%
3-Year ReturnCumulative with dividends-95.7%-19.3%
5-Year ReturnCumulative with dividends-99.4%-32.7%
10-Year ReturnCumulative with dividends-100.0%+369.1%
CAGR (3Y)Annualised 3-year return-64.9%-6.9%
RGEN leads this category, winning 6 of 6 comparable metrics.

Risk & Volatility

RGEN leads this category, winning 2 of 2 comparable metrics.

RGEN is the less volatile stock with a 1.76 beta — it tends to amplify market swings less than BRTX's 2.21 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. RGEN currently trades 71.9% from its 52-week high vs BRTX's 11.0% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricBRTX logoBRTXBioRestorative Th…RGEN logoRGENRepligen Corporat…
Beta (5Y)Sensitivity to S&P 5002.21x1.76x
52-Week HighHighest price in past year$2.05$175.77
52-Week LowLowest price in past year$0.19$109.52
% of 52W HighCurrent price vs 52-week peak+11.0%+71.9%
RSI (14)Momentum oscillator 0–10046.855.1
Avg Volume (50D)Average daily shares traded5.4M905K
RGEN leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.
MetricBRTX logoBRTXBioRestorative Th…RGEN logoRGENRepligen Corporat…
Analyst RatingConsensus buy/hold/sellBuy
Price TargetConsensus 12-month target$168.00
# AnalystsCovering analysts23
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

RGEN leads in 4 of 6 categories (Income & Cash Flow, Profitability & Efficiency). BRTX leads in 1 (Valuation Metrics).

Best OverallRepligen Corporation (RGEN)Leads 4 of 6 categories
Loading custom metrics...

BRTX vs RGEN: Frequently Asked Questions

8 questions · data-driven answers · updated daily

01

Is BRTX or RGEN a better buy right now?

For growth investors, BioRestorative Therapies, Inc.

(BRTX) is the stronger pick with 175. 0% revenue growth year-over-year, versus 16. 4% for Repligen Corporation (RGEN). Repligen Corporation (RGEN) offers the better valuation at 147. 0x trailing P/E (64. 3x forward), making it the more compelling value choice. Analysts rate Repligen Corporation (RGEN) a "Buy" — based on 23 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — BRTX or RGEN?

Over the past 5 years, Repligen Corporation (RGEN) delivered a total return of -32.

7%, compared to -99. 4% for BioRestorative Therapies, Inc. (BRTX). Over 10 years, the gap is even starker: RGEN returned +369. 1% versus BRTX's -100. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — BRTX or RGEN?

By beta (market sensitivity over 5 years), Repligen Corporation (RGEN) is the lower-risk stock at 1.

76β versus BioRestorative Therapies, Inc. 's 2. 21β — meaning BRTX is approximately 26% more volatile than RGEN relative to the S&P 500.

04

Which is growing faster — BRTX or RGEN?

By revenue growth (latest reported year), BioRestorative Therapies, Inc.

(BRTX) is pulling ahead at 175. 0% versus 16. 4% for Repligen Corporation (RGEN). On earnings-per-share growth, the picture is similar: Repligen Corporation grew EPS 287. 0% year-over-year, compared to 53. 0% for BioRestorative Therapies, Inc.. Over a 3-year CAGR, BRTX leads at 105. 8% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — BRTX or RGEN?

Repligen Corporation (RGEN) is the more profitable company, earning 6.

6% net margin versus -22. 4% for BioRestorative Therapies, Inc. — meaning it keeps 6. 6% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: RGEN leads at 8. 1% versus -28. 8% for BRTX. At the gross margin level — before operating expenses — BRTX leads at 93. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Which pays a better dividend — BRTX or RGEN?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

07

Is BRTX or RGEN better for a retirement portfolio?

For long-horizon retirement investors, Repligen Corporation (RGEN) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (+369.

1% 10Y return). BioRestorative Therapies, Inc. (BRTX) carries a higher beta of 2. 21 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (RGEN: +369. 1%, BRTX: -100. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

08

What are the main differences between BRTX and RGEN?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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BRTX

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 47%
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RGEN

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 7%
  • Net Margin > 5%
Run This Screen
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(BRTX: -94.9% · RGEN: 14.8%)

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