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CAPR vs RARE vs SRPT vs CRSP vs EDIT

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
CAPR
Capricor Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.39B
5Y Perf.+554.7%
RARE
Ultragenyx Pharmaceutical Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$2.57B
5Y Perf.-61.8%
SRPT
Sarepta Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$2.11B
5Y Perf.-86.9%
CRSP
CRISPR Therapeutics AG

Biotechnology

HealthcareNASDAQ • CH
Market Cap$5.29B
5Y Perf.-15.1%
EDIT
Editas Medicine, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$304M
5Y Perf.-88.5%

CAPR vs RARE vs SRPT vs CRSP vs EDIT — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
CAPR logoCAPR
RARE logoRARE
SRPT logoSRPT
CRSP logoCRSP
EDIT logoEDIT
IndustryBiotechnologyBiotechnologyBiotechnologyBiotechnologyBiotechnology
Market Cap$1.39B$2.57B$2.11B$5.29B$304M
Revenue (TTM)$11M$669M$2.18B$4M$0.00
Net Income (TTM)$-82M$-609M$65M$-569M$-160M
Gross Margin-5.8%83.6%34.4%-41.7%
Operating Margin-7.8%-83.9%-1.9%-134.1%
Forward P/E5.9x
Total Debt$1M$1.28B$1.04B$395M$18M
Cash & Equiv.$11M$434M$801M$355M$147M

CAPR vs RARE vs SRPT vs CRSP vs EDITLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

CAPR
RARE
SRPT
CRSP
EDIT
StockMay 20May 26Return
Capricor Therapeuti… (CAPR)100654.7+554.7%
Ultragenyx Pharmace… (RARE)10038.2-61.8%
Sarepta Therapeutic… (SRPT)10013.1-86.9%
CRISPR Therapeutics… (CRSP)10084.9-15.1%
Editas Medicine, In… (EDIT)10011.5-88.5%

Price return only. Dividends and distributions are not included.

Quick Verdict: CAPR vs RARE vs SRPT vs CRSP vs EDIT

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: RARE and SRPT are tied at the top with 2 categories each (5-stock set) — the right choice depends on your priorities. Sarepta Therapeutics, Inc. is the stronger pick specifically for profitability and margin quality and operational efficiency and capital deployment. CAPR also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
CAPR
Capricor Therapeutics, Inc.
The Defensive Pick

CAPR ranks third and is worth considering specifically for sleep-well-at-night and defensive.

  • Lower volatility, beta 1.77, Low D/E 1.0%, current ratio 7.77x
  • Beta 1.77, current ratio 7.77x
  • +335.9% vs SRPT's -45.4%
Best for: sleep-well-at-night and defensive
RARE
Ultragenyx Pharmaceutical Inc.
The Income Pick

RARE carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.

  • Dividend streak 1 yrs, beta 1.36
  • Rev growth 20.1%, EPS growth 7.3%, 3Y rev CAGR 22.8%
  • 20.1% revenue growth vs EDIT's -100.0%
  • Beta 1.36 vs EDIT's 2.45
Best for: income & stability and growth exposure
SRPT
Sarepta Therapeutics, Inc.
The Quality Compounder

SRPT is the #2 pick in this set and the best alternative if quality and efficiency is your priority.

  • 3.0% margin vs CRSP's -138.6%
  • 1.9% ROA vs EDIT's -74.2%
Best for: quality and efficiency
CRSP
CRISPR Therapeutics AG
The Long-Run Compounder

CRSP is the clearest fit if your priority is long-term compounding.

  • 289.1% 10Y total return vs CAPR's -14.7%
Best for: long-term compounding
EDIT
Editas Medicine, Inc.
The Healthcare Pick

Among these 5 stocks, EDIT doesn't own a clear edge in any measured category.

Best for: healthcare exposure
See the full category breakdown
CategoryWinnerWhy
GrowthRARE logoRARE20.1% revenue growth vs EDIT's -100.0%
Quality / MarginsSRPT logoSRPT3.0% margin vs CRSP's -138.6%
Stability / SafetyRARE logoRAREBeta 1.36 vs EDIT's 2.45
DividendsTieNone of these 5 stocks pay a meaningful dividend
Momentum (1Y)CAPR logoCAPR+335.9% vs SRPT's -45.4%
Efficiency (ROA)SRPT logoSRPT1.9% ROA vs EDIT's -74.2%

CAPR vs RARE vs SRPT vs CRSP vs EDIT — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

CAPRCapricor Therapeutics, Inc.

Segment breakdown not available.

RAREUltragenyx Pharmaceutical Inc.
FY 2025
Product
54.8%$369M
Royalty
45.2%$304M
SRPTSarepta Therapeutics, Inc.

Segment breakdown not available.

CRSPCRISPR Therapeutics AG
FY 2025
Grant
100.0%$4M
EDITEditas Medicine, Inc.
FY 2025
Reportable Segment
100.0%$41M

CAPR vs RARE vs SRPT vs CRSP vs EDIT — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLSRPTLAGGINGEDIT

Income & Cash Flow (Last 12 Months)

SRPT leads this category, winning 4 of 6 comparable metrics.

SRPT and EDIT operate at a comparable scale, with $2.2B and $0 in trailing revenue. SRPT is the more profitable business, keeping 3.0% of every revenue dollar as net income compared to CRSP's -138.6%. On growth, CRSP holds the edge at +68.6% YoY revenue growth, suggesting stronger near-term business momentum.

MetricCAPR logoCAPRCapricor Therapeu…RARE logoRAREUltragenyx Pharma…SRPT logoSRPTSarepta Therapeut…CRSP logoCRSPCRISPR Therapeuti…EDIT logoEDITEditas Medicine, …
RevenueTrailing 12 months$11M$669M$2.2B$4M$0
EBITDAEarnings before interest/tax-$85M-$536M-$6M-$535M$0
Net IncomeAfter-tax profit-$82M-$609M$65M-$569M-$160M
Free Cash FlowCash after capex-$45M-$487M$107M-$401M-$166M
Gross MarginGross profit ÷ Revenue-5.8%+83.6%+34.4%-41.7%
Operating MarginEBIT ÷ Revenue-7.8%-83.9%-1.9%-134.1%
Net MarginNet income ÷ Revenue-7.4%-91.0%+3.0%-138.6%
FCF MarginFCF ÷ Revenue-4.0%-72.8%+4.9%-97.8%
Rev. Growth (YoY)Latest quarter vs prior year-100.0%-2.4%-1.9%+68.6%-151.6%
EPS Growth (YoY)Latest quarter vs prior year-42.1%-17.2%+162.6%+19.0%+105.5%
SRPT leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

SRPT leads this category, winning 2 of 3 comparable metrics.
MetricCAPR logoCAPRCapricor Therapeu…RARE logoRAREUltragenyx Pharma…SRPT logoSRPTSarepta Therapeut…CRSP logoCRSPCRISPR Therapeuti…EDIT logoEDITEditas Medicine, …
Market CapShares × price$1.4B$2.6B$2.1B$5.3B$304M
Enterprise ValueMkt cap + debt − cash$1.4B$3.4B$2.3B$5.3B$176M
Trailing P/EPrice ÷ TTM EPS-26.42x-4.48x-2.80x-8.47x-1.73x
Forward P/EPrice ÷ next-FY EPS est.5.91x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple
Price / SalesMarket cap ÷ Revenue62.36x3.82x0.96x1506.63x
Price / BookPrice ÷ Book value/share7.36x1.83x2.57x10.11x
Price / FCFMarket cap ÷ FCF
SRPT leads this category, winning 2 of 3 comparable metrics.

Profitability & Efficiency

SRPT leads this category, winning 5 of 9 comparable metrics.

SRPT delivers a 4.9% return on equity — every $100 of shareholder capital generates $5 in annual profit, vs $-6 for RARE. CAPR carries lower financial leverage with a 0.01x debt-to-equity ratio, signaling a more conservative balance sheet compared to SRPT's 0.91x. On the Piotroski fundamental quality scale (0–9), CAPR scores 4/9 vs EDIT's 1/9, reflecting mixed financial health.

MetricCAPR logoCAPRCapricor Therapeu…RARE logoRAREUltragenyx Pharma…SRPT logoSRPTSarepta Therapeut…CRSP logoCRSPCRISPR Therapeuti…EDIT logoEDITEditas Medicine, …
ROE (TTM)Return on equity-97.8%-6.1%+4.9%-30.9%-5.2%
ROA (TTM)Return on assets-64.8%-45.8%+1.9%-24.5%-74.2%
ROICReturn on invested capital-43.8%-89.4%-31.4%-22.3%
ROCEReturn on capital employed-48.1%-46.4%-24.0%-26.6%
Piotroski ScoreFundamental quality 0–944411
Debt / EquityFinancial leverage0.01x0.91x0.21x0.66x
Net DebtTotal debt minus cash-$10M$842M$238M$40M-$129M
Cash & Equiv.Liquid assets$11M$434M$801M$355M$147M
Total DebtShort + long-term debt$1M$1.3B$1.0B$395M$18M
Interest CoverageEBIT ÷ Interest expense-14.49x-14.00x
SRPT leads this category, winning 5 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

CAPR leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in CAPR five years ago would be worth $87,804 today (with dividends reinvested), compared to $994 for EDIT. Over the past 12 months, CAPR leads with a +335.9% total return vs SRPT's -45.4%. The 3-year compound annual growth rate (CAGR) favors CAPR at 98.2% vs SRPT's -46.0% — a key indicator of consistent wealth creation.

MetricCAPR logoCAPRCapricor Therapeu…RARE logoRAREUltragenyx Pharma…SRPT logoSRPTSarepta Therapeut…CRSP logoCRSPCRISPR Therapeuti…EDIT logoEDITEditas Medicine, …
YTD ReturnYear-to-date+7.3%+10.7%-6.4%+2.0%+51.7%
1-Year ReturnPast 12 months+335.9%-27.4%-45.4%+51.7%+123.7%
3-Year ReturnCumulative with dividends+679.0%-44.5%-84.3%-2.0%-67.7%
5-Year ReturnCumulative with dividends+778.0%-76.1%-71.5%-46.0%-90.1%
10-Year ReturnCumulative with dividends-14.7%-59.4%+13.2%+289.1%-89.7%
CAGR (3Y)Annualised 3-year return+98.2%-17.8%-46.0%-0.7%-31.4%
CAPR leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — CAPR and RARE each lead in 1 of 2 comparable metrics.

RARE is the less volatile stock with a 1.36 beta — it tends to amplify market swings less than EDIT's 2.45 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. CAPR currently trades 75.3% from its 52-week high vs SRPT's 45.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricCAPR logoCAPRCapricor Therapeu…RARE logoRAREUltragenyx Pharma…SRPT logoSRPTSarepta Therapeut…CRSP logoCRSPCRISPR Therapeuti…EDIT logoEDITEditas Medicine, …
Beta (5Y)Sensitivity to S&P 5001.77x1.36x1.95x1.87x2.45x
52-Week HighHighest price in past year$40.37$42.37$44.14$78.48$4.54
52-Week LowLowest price in past year$4.30$18.29$10.42$34.12$1.29
% of 52W HighCurrent price vs 52-week peak+75.3%+61.6%+45.2%+69.9%+68.5%
RSI (14)Momentum oscillator 0–10053.667.748.649.452.5
Avg Volume (50D)Average daily shares traded1.3M1.8M2.9M1.9M1.6M
Evenly matched — CAPR and RARE each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: CAPR as "Buy", RARE as "Buy", SRPT as "Buy", CRSP as "Buy", EDIT as "Buy". Consensus price targets imply 85.1% upside for RARE (target: $48) vs 14.9% for CRSP (target: $63).

MetricCAPR logoCAPRCapricor Therapeu…RARE logoRAREUltragenyx Pharma…SRPT logoSRPTSarepta Therapeut…CRSP logoCRSPCRISPR Therapeuti…EDIT logoEDITEditas Medicine, …
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuyBuy
Price TargetConsensus 12-month target$47.75$48.36$25.29$63.00$5.00
# AnalystsCovering analysts1033543825
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises1
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%+1.2%0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

SRPT leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). CAPR leads in 1 (Total Returns). 1 tied.

Best OverallSarepta Therapeutics, Inc. (SRPT)Leads 3 of 6 categories
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CAPR vs RARE vs SRPT vs CRSP vs EDIT: Key Questions Answered

9 questions · data-driven answers · updated daily

01

Is CAPR or RARE or SRPT or CRSP or EDIT a better buy right now?

For growth investors, Ultragenyx Pharmaceutical Inc.

(RARE) is the stronger pick with 20. 1% revenue growth year-over-year, versus -100. 0% for Editas Medicine, Inc. (EDIT). Analysts rate Capricor Therapeutics, Inc. (CAPR) a "Buy" — based on 10 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — CAPR or RARE or SRPT or CRSP or EDIT?

Over the past 5 years, Capricor Therapeutics, Inc.

(CAPR) delivered a total return of +778. 0%, compared to -90. 1% for Editas Medicine, Inc. (EDIT). Over 10 years, the gap is even starker: CRSP returned +289. 1% versus EDIT's -89. 7%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — CAPR or RARE or SRPT or CRSP or EDIT?

By beta (market sensitivity over 5 years), Ultragenyx Pharmaceutical Inc.

(RARE) is the lower-risk stock at 1. 36β versus Editas Medicine, Inc. 's 2. 45β — meaning EDIT is approximately 79% more volatile than RARE relative to the S&P 500. On balance sheet safety, Capricor Therapeutics, Inc. (CAPR) carries a lower debt/equity ratio of 1% versus 91% for Sarepta Therapeutics, Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — CAPR or RARE or SRPT or CRSP or EDIT?

By revenue growth (latest reported year), Ultragenyx Pharmaceutical Inc.

(RARE) is pulling ahead at 20. 1% versus -100. 0% for Editas Medicine, Inc. (EDIT). On earnings-per-share growth, the picture is similar: Editas Medicine, Inc. grew EPS 37. 5% year-over-year, compared to -404. 7% for Sarepta Therapeutics, Inc.. Over a 3-year CAGR, CAPR leads at 349. 7% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — CAPR or RARE or SRPT or CRSP or EDIT?

Editas Medicine, Inc.

(EDIT) is the more profitable company, earning 0. 0% net margin versus -165. 7% for CRISPR Therapeutics AG — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: EDIT leads at 0. 0% versus -161. 9% for CRSP. At the gross margin level — before operating expenses — RARE leads at 83. 8%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is CAPR or RARE or SRPT or CRSP or EDIT more undervalued right now?

Analyst consensus price targets imply the most upside for RARE: 85.

1% to $48. 36.

07

Which pays a better dividend — CAPR or RARE or SRPT or CRSP or EDIT?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

08

Is CAPR or RARE or SRPT or CRSP or EDIT better for a retirement portfolio?

For long-horizon retirement investors, Ultragenyx Pharmaceutical Inc.

(RARE) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding. Editas Medicine, Inc. (EDIT) carries a higher beta of 2. 45 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (RARE: -59. 4%, EDIT: -89. 7%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between CAPR and RARE and SRPT and CRSP and EDIT?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: CAPR is a small-cap quality compounder stock; RARE is a small-cap high-growth stock; SRPT is a small-cap high-growth stock; CRSP is a small-cap quality compounder stock; EDIT is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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