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Stock Comparison

CLGN vs ITGR

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
CLGN
CollPlant Biotechnologies Ltd.

Biotechnology

HealthcareNASDAQ • IL
Market Cap$5M
5Y Perf.-96.2%
ITGR
Integer Holdings Corporation

Medical - Devices

HealthcareNYSE • US
Market Cap$3.03B
5Y Perf.+11.0%

CLGN vs ITGR — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
CLGN logoCLGN
ITGR logoITGR
IndustryBiotechnologyMedical - Devices
Market Cap$5M$3.03B
Revenue (TTM)$2M$1.85B
Net Income (TTM)$-12M$142M
Gross Margin25.1%23.3%
Operating Margin-497.3%10.4%
Forward P/E13.5x
Total Debt$3M$1.40B
Cash & Equiv.$12M$17M

CLGN vs ITGRLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

CLGN
ITGR
StockMay 20May 26Return
CollPlant Biotechno… (CLGN)1003.8-96.2%
Integer Holdings Co… (ITGR)100111.0+11.0%

Price return only. Dividends and distributions are not included.

Quick Verdict: CLGN vs ITGR

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: ITGR leads in 5 of 6 categories, making it the strongest pick for growth and revenue expansion and profitability and margin quality. As sector peers, any of these can serve as alternatives in the same allocation.
CLGN
CollPlant Biotechnologies Ltd.
The Defensive Pick

CLGN is the clearest fit if your priority is sleep-well-at-night.

  • Lower volatility, beta 0.89, Low D/E 22.9%, current ratio 4.44x
Best for: sleep-well-at-night
ITGR
Integer Holdings Corporation
The Income Pick

ITGR carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.

  • beta 0.72
  • Rev growth 7.6%, EPS growth -15.0%, 3Y rev CAGR 11.5%
  • 165.1% 10Y total return vs CLGN's -95.6%
Best for: income & stability and growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthITGR logoITGR7.6% revenue growth vs CLGN's -95.3%
Quality / MarginsITGR logoITGR7.7% margin vs CLGN's -491.3%
Stability / SafetyITGR logoITGRBeta 0.72 vs CLGN's 0.89
DividendsTieNeither stock pays a meaningful dividend
Momentum (1Y)ITGR logoITGR-26.1% vs CLGN's -78.9%
Efficiency (ROA)ITGR logoITGR4.2% ROA vs CLGN's -86.3%, ROIC 5.4% vs -273.5%

CLGN vs ITGR — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

CLGNCollPlant Biotechnologies Ltd.

Segment breakdown not available.

ITGRInteger Holdings Corporation
FY 2025
Cardio And Vascular
59.7%$1.1B
Cardiac Rhythm Management & Neuromodulation
36.1%$669M
Other Markets
4.2%$78M

CLGN vs ITGR — Financial Metrics

Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLITGRLAGGINGCLGN

Income & Cash Flow (Last 12 Months)

ITGR leads this category, winning 4 of 6 comparable metrics.

ITGR is the larger business by revenue, generating $1.8B annually — 747.4x CLGN's $2M. ITGR is the more profitable business, keeping 7.7% of every revenue dollar as net income compared to CLGN's -4.9%. On growth, CLGN holds the edge at +18.3% YoY revenue growth, suggesting stronger near-term business momentum.

MetricCLGN logoCLGNCollPlant Biotech…ITGR logoITGRInteger Holdings …
RevenueTrailing 12 months$2M$1.8B
EBITDAEarnings before interest/tax-$11M$328M
Net IncomeAfter-tax profit-$12M$142M
Free Cash FlowCash after capex-$10M$168M
Gross MarginGross profit ÷ Revenue+25.1%+23.3%
Operating MarginEBIT ÷ Revenue-5.0%+10.4%
Net MarginNet income ÷ Revenue-4.9%+7.7%
FCF MarginFCF ÷ Revenue-4.0%+9.1%
Rev. Growth (YoY)Latest quarter vs prior year+18.3%+0.8%
EPS Growth (YoY)Latest quarter vs prior year+28.9%+172.7%
ITGR leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

CLGN leads this category, winning 2 of 3 comparable metrics.
MetricCLGN logoCLGNCollPlant Biotech…ITGR logoITGRInteger Holdings …
Market CapShares × price$5M$3.0B
Enterprise ValueMkt cap + debt − cash-$4M$4.4B
Trailing P/EPrice ÷ TTM EPS-0.27x30.42x
Forward P/EPrice ÷ next-FY EPS est.13.55x
PEG RatioP/E ÷ EPS growth rate6.91x
EV / EBITDAEnterprise value multiple13.15x
Price / SalesMarket cap ÷ Revenue8.74x1.64x
Price / BookPrice ÷ Book value/share0.33x1.79x
Price / FCFMarket cap ÷ FCF28.78x
CLGN leads this category, winning 2 of 3 comparable metrics.

Profitability & Efficiency

ITGR leads this category, winning 6 of 9 comparable metrics.

ITGR delivers a 8.2% return on equity — every $100 of shareholder capital generates $8 in annual profit, vs $-131 for CLGN. CLGN carries lower financial leverage with a 0.23x debt-to-equity ratio, signaling a more conservative balance sheet compared to ITGR's 0.80x. On the Piotroski fundamental quality scale (0–9), ITGR scores 5/9 vs CLGN's 1/9, reflecting solid financial health.

MetricCLGN logoCLGNCollPlant Biotech…ITGR logoITGRInteger Holdings …
ROE (TTM)Return on equity-130.7%+8.2%
ROA (TTM)Return on assets-86.3%+4.2%
ROICReturn on invested capital-2.7%+5.4%
ROCEReturn on capital employed-74.0%+6.9%
Piotroski ScoreFundamental quality 0–915
Debt / EquityFinancial leverage0.23x0.80x
Net DebtTotal debt minus cash-$9M$1.4B
Cash & Equiv.Liquid assets$12M$17M
Total DebtShort + long-term debt$3M$1.4B
Interest CoverageEBIT ÷ Interest expense-70.95x5.07x
ITGR leads this category, winning 6 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

ITGR leads this category, winning 6 of 6 comparable metrics.

A $10,000 investment in ITGR five years ago would be worth $9,252 today (with dividends reinvested), compared to $286 for CLGN. Over the past 12 months, ITGR leads with a -26.1% total return vs CLGN's -78.9%. The 3-year compound annual growth rate (CAGR) favors ITGR at 2.9% vs CLGN's -61.5% — a key indicator of consistent wealth creation.

MetricCLGN logoCLGNCollPlant Biotech…ITGR logoITGRInteger Holdings …
YTD ReturnYear-to-date-73.5%+14.5%
1-Year ReturnPast 12 months-78.9%-26.1%
3-Year ReturnCumulative with dividends-94.3%+8.8%
5-Year ReturnCumulative with dividends-97.1%-7.5%
10-Year ReturnCumulative with dividends-95.6%+165.1%
CAGR (3Y)Annualised 3-year return-61.5%+2.9%
ITGR leads this category, winning 6 of 6 comparable metrics.

Risk & Volatility

ITGR leads this category, winning 2 of 2 comparable metrics.

ITGR is the less volatile stock with a 0.72 beta — it tends to amplify market swings less than CLGN's 0.89 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ITGR currently trades 71.0% from its 52-week high vs CLGN's 7.9% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricCLGN logoCLGNCollPlant Biotech…ITGR logoITGRInteger Holdings …
Beta (5Y)Sensitivity to S&P 5000.89x0.72x
52-Week HighHighest price in past year$4.98$123.78
52-Week LowLowest price in past year$0.28$62.00
% of 52W HighCurrent price vs 52-week peak+7.9%+71.0%
RSI (14)Momentum oscillator 0–10046.650.9
Avg Volume (50D)Average daily shares traded91K628K
ITGR leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.
MetricCLGN logoCLGNCollPlant Biotech…ITGR logoITGRInteger Holdings …
Analyst RatingConsensus buy/hold/sellBuy
Price TargetConsensus 12-month target$98.00
# AnalystsCovering analysts14
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%+1.7%
Insufficient data to determine a leader in this category.
Key Takeaway

ITGR leads in 4 of 6 categories (Income & Cash Flow, Profitability & Efficiency). CLGN leads in 1 (Valuation Metrics).

Best OverallInteger Holdings Corporation (ITGR)Leads 4 of 6 categories
Loading custom metrics...

CLGN vs ITGR: Frequently Asked Questions

8 questions · data-driven answers · updated daily

01

Is CLGN or ITGR a better buy right now?

For growth investors, Integer Holdings Corporation (ITGR) is the stronger pick with 7.

6% revenue growth year-over-year, versus -95. 3% for CollPlant Biotechnologies Ltd. (CLGN). Integer Holdings Corporation (ITGR) offers the better valuation at 30. 4x trailing P/E (13. 5x forward), making it the more compelling value choice. Analysts rate Integer Holdings Corporation (ITGR) a "Buy" — based on 14 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — CLGN or ITGR?

Over the past 5 years, Integer Holdings Corporation (ITGR) delivered a total return of -7.

5%, compared to -97. 1% for CollPlant Biotechnologies Ltd. (CLGN). Over 10 years, the gap is even starker: ITGR returned +165. 1% versus CLGN's -95. 6%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — CLGN or ITGR?

By beta (market sensitivity over 5 years), Integer Holdings Corporation (ITGR) is the lower-risk stock at 0.

72β versus CollPlant Biotechnologies Ltd. 's 0. 89β — meaning CLGN is approximately 24% more volatile than ITGR relative to the S&P 500. On balance sheet safety, CollPlant Biotechnologies Ltd. (CLGN) carries a lower debt/equity ratio of 23% versus 80% for Integer Holdings Corporation — giving it more financial flexibility in a downturn.

04

Which is growing faster — CLGN or ITGR?

By revenue growth (latest reported year), Integer Holdings Corporation (ITGR) is pulling ahead at 7.

6% versus -95. 3% for CollPlant Biotechnologies Ltd. (CLGN). On earnings-per-share growth, the picture is similar: Integer Holdings Corporation grew EPS -15. 0% year-over-year, compared to -133. 9% for CollPlant Biotechnologies Ltd.. Over a 3-year CAGR, ITGR leads at 11. 5% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — CLGN or ITGR?

Integer Holdings Corporation (ITGR) is the more profitable company, earning 5.

6% net margin versus -32. 3% for CollPlant Biotechnologies Ltd. — meaning it keeps 5. 6% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ITGR leads at 11. 3% versus -33. 5% for CLGN. At the gross margin level — before operating expenses — ITGR leads at 23. 1%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Which pays a better dividend — CLGN or ITGR?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

07

Is CLGN or ITGR better for a retirement portfolio?

For long-horizon retirement investors, Integer Holdings Corporation (ITGR) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

72), +165. 1% 10Y return). Both have compounded well over 10 years (ITGR: +165. 1%, CLGN: -95. 6%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

08

What are the main differences between CLGN and ITGR?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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ITGR

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  • Market Cap > $100B
  • Net Margin > 5%
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