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Stock Comparison

CLLS vs EDIT

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
CLLS
Cellectis S.A.

Biotechnology

HealthcareNASDAQ • FR
Market Cap$280M
5Y Perf.-79.1%
EDIT
Editas Medicine, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$297M
5Y Perf.-88.8%

CLLS vs EDIT — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
CLLS logoCLLS
EDIT logoEDIT
IndustryBiotechnologyBiotechnology
Market Cap$280M$297M
Revenue (TTM)$75M$0.00
Net Income (TTM)$-35M$-160M
Gross Margin87.6%
Operating Margin-35.1%
Total Debt$91M$18M
Cash & Equiv.$143M$147M

CLLS vs EDITLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

CLLS
EDIT
StockMay 20May 26Return
Cellectis S.A. (CLLS)10020.9-79.1%
Editas Medicine, In… (EDIT)10011.2-88.8%

Price return only. Dividends and distributions are not included.

Quick Verdict: CLLS vs EDIT

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: CLLS leads in 4 of 5 categories, making it the strongest pick for growth and revenue expansion and capital preservation and lower volatility. As sector peers, any of these can serve as alternatives in the same allocation.
CLLS
Cellectis S.A.
The Income Pick

CLLS carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.

  • beta 1.64
  • Rev growth 54.0%, EPS growth 76.8%, 3Y rev CAGR 11.0%
  • -88.4% 10Y total return vs EDIT's -90.0%
Best for: income & stability and growth exposure
EDIT
Editas Medicine, Inc.
The Specific-Use Pick

In this particular matchup, EDIT is outpaced on most metrics by others in the set.

Best for: healthcare exposure
See the full category breakdown
CategoryWinnerWhy
GrowthCLLS logoCLLS54.0% revenue growth vs EDIT's -100.0%
Stability / SafetyCLLS logoCLLSBeta 1.64 vs EDIT's 2.52
DividendsTieNeither stock pays a meaningful dividend
Momentum (1Y)CLLS logoCLLS+152.3% vs EDIT's +127.8%
Efficiency (ROA)CLLS logoCLLS-9.8% ROA vs EDIT's -74.2%

CLLS vs EDIT — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

CLLSCellectis S.A.
FY 2022
Therapeutics
100.0%$26M
EDITEditas Medicine, Inc.
FY 2025
Reportable Segment
100.0%$41M

CLLS vs EDIT — Financial Metrics

Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLCLLSLAGGINGEDIT

Income & Cash Flow (Last 12 Months)

Evenly matched — CLLS and EDIT each lead in 1 of 2 comparable metrics.

CLLS and EDIT operate at a comparable scale, with $75M and $0 in trailing revenue. On growth, CLLS holds the edge at +117.1% YoY revenue growth, suggesting stronger near-term business momentum.

MetricCLLS logoCLLSCellectis S.A.EDIT logoEDITEditas Medicine, …
RevenueTrailing 12 months$75M$0
EBITDAEarnings before interest/tax-$6M$0
Net IncomeAfter-tax profit-$35M-$160M
Free Cash FlowCash after capex-$33M-$166M
Gross MarginGross profit ÷ Revenue+87.6%
Operating MarginEBIT ÷ Revenue-35.1%
Net MarginNet income ÷ Revenue-47.0%
FCF MarginFCF ÷ Revenue-43.5%
Rev. Growth (YoY)Latest quarter vs prior year+117.1%-151.6%
EPS Growth (YoY)Latest quarter vs prior year+102.6%+105.5%
Evenly matched — CLLS and EDIT each lead in 1 of 2 comparable metrics.

Valuation Metrics

CLLS leads this category, winning 2 of 2 comparable metrics.
MetricCLLS logoCLLSCellectis S.A.EDIT logoEDITEditas Medicine, …
Market CapShares × price$280M$297M
Enterprise ValueMkt cap + debt − cash$228M$168M
Trailing P/EPrice ÷ TTM EPS-9.41x-1.68x
Forward P/EPrice ÷ next-FY EPS est.
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple
Price / SalesMarket cap ÷ Revenue6.75x
Price / BookPrice ÷ Book value/share2.67x9.85x
Price / FCFMarket cap ÷ FCF14.35x
CLLS leads this category, winning 2 of 2 comparable metrics.

Profitability & Efficiency

Evenly matched — CLLS and EDIT each lead in 3 of 6 comparable metrics.

CLLS delivers a -31.8% return on equity — every $100 of shareholder capital generates $-32 in annual profit, vs $-5 for EDIT. EDIT carries lower financial leverage with a 0.66x debt-to-equity ratio, signaling a more conservative balance sheet compared to CLLS's 0.70x. On the Piotroski fundamental quality scale (0–9), CLLS scores 7/9 vs EDIT's 1/9, reflecting strong financial health.

MetricCLLS logoCLLSCellectis S.A.EDIT logoEDITEditas Medicine, …
ROE (TTM)Return on equity-31.8%-5.2%
ROA (TTM)Return on assets-9.8%-74.2%
ROICReturn on invested capital-79.6%
ROCEReturn on capital employed-30.0%
Piotroski ScoreFundamental quality 0–971
Debt / EquityFinancial leverage0.70x0.66x
Net DebtTotal debt minus cash-$52M-$129M
Cash & Equiv.Liquid assets$143M$147M
Total DebtShort + long-term debt$91M$18M
Interest CoverageEBIT ÷ Interest expense-3.44x
Evenly matched — CLLS and EDIT each lead in 3 of 6 comparable metrics.

Total Returns (Dividends Reinvested)

CLLS leads this category, winning 5 of 6 comparable metrics.

A $10,000 investment in CLLS five years ago would be worth $2,368 today (with dividends reinvested), compared to $888 for EDIT. Over the past 12 months, CLLS leads with a +152.3% total return vs EDIT's +127.8%. The 3-year compound annual growth rate (CAGR) favors CLLS at 26.7% vs EDIT's -32.0% — a key indicator of consistent wealth creation.

MetricCLLS logoCLLSCellectis S.A.EDIT logoEDITEditas Medicine, …
YTD ReturnYear-to-date-19.6%+47.8%
1-Year ReturnPast 12 months+152.3%+127.8%
3-Year ReturnCumulative with dividends+103.2%-68.5%
5-Year ReturnCumulative with dividends-76.3%-91.1%
10-Year ReturnCumulative with dividends-88.4%-90.0%
CAGR (3Y)Annualised 3-year return+26.7%-32.0%
CLLS leads this category, winning 5 of 6 comparable metrics.

Risk & Volatility

CLLS leads this category, winning 2 of 2 comparable metrics.

CLLS is the less volatile stock with a 1.64 beta — it tends to amplify market swings less than EDIT's 2.52 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. CLLS currently trades 70.4% from its 52-week high vs EDIT's 66.7% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricCLLS logoCLLSCellectis S.A.EDIT logoEDITEditas Medicine, …
Beta (5Y)Sensitivity to S&P 5001.64x2.52x
52-Week HighHighest price in past year$5.48$4.54
52-Week LowLowest price in past year$1.33$1.29
% of 52W HighCurrent price vs 52-week peak+70.4%+66.7%
RSI (14)Momentum oscillator 0–10053.257.5
Avg Volume (50D)Average daily shares traded42K1.6M
CLLS leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Wall Street rates CLLS as "Buy" and EDIT as "Buy". Consensus price targets imply 98.0% upside for EDIT (target: $6) vs 55.4% for CLLS (target: $6).

MetricCLLS logoCLLSCellectis S.A.EDIT logoEDITEditas Medicine, …
Analyst RatingConsensus buy/hold/sellBuyBuy
Price TargetConsensus 12-month target$6.00$6.00
# AnalystsCovering analysts1725
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

CLLS leads in 3 of 6 categories — strongest in Valuation Metrics and Total Returns. 2 categories are tied.

Best OverallCellectis S.A. (CLLS)Leads 3 of 6 categories
Loading custom metrics...

CLLS vs EDIT: Frequently Asked Questions

8 questions · data-driven answers · updated daily

01

Is CLLS or EDIT a better buy right now?

For growth investors, Cellectis S.

A. (CLLS) is the stronger pick with 54. 0% revenue growth year-over-year, versus -100. 0% for Editas Medicine, Inc. (EDIT). Analysts rate Cellectis S. A. (CLLS) a "Buy" — based on 17 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — CLLS or EDIT?

Over the past 5 years, Cellectis S.

A. (CLLS) delivered a total return of -76. 3%, compared to -91. 1% for Editas Medicine, Inc. (EDIT). Over 10 years, the gap is even starker: CLLS returned -88. 4% versus EDIT's -90. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — CLLS or EDIT?

By beta (market sensitivity over 5 years), Cellectis S.

A. (CLLS) is the lower-risk stock at 1. 64β versus Editas Medicine, Inc. 's 2. 52β — meaning EDIT is approximately 54% more volatile than CLLS relative to the S&P 500. On balance sheet safety, Editas Medicine, Inc. (EDIT) carries a lower debt/equity ratio of 66% versus 70% for Cellectis S. A. — giving it more financial flexibility in a downturn.

04

Which is growing faster — CLLS or EDIT?

By revenue growth (latest reported year), Cellectis S.

A. (CLLS) is pulling ahead at 54. 0% versus -100. 0% for Editas Medicine, Inc. (EDIT). On earnings-per-share growth, the picture is similar: Cellectis S. A. grew EPS 76. 8% year-over-year, compared to 37. 5% for Editas Medicine, Inc.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — CLLS or EDIT?

Editas Medicine, Inc.

(EDIT) is the more profitable company, earning 0. 0% net margin versus -88. 6% for Cellectis S. A. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: EDIT leads at 0. 0% versus -143. 5% for CLLS. At the gross margin level — before operating expenses — CLLS leads at 77. 9%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Which pays a better dividend — CLLS or EDIT?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

07

Is CLLS or EDIT better for a retirement portfolio?

For long-horizon retirement investors, Cellectis S.

A. (CLLS) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding. Editas Medicine, Inc. (EDIT) carries a higher beta of 2. 52 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (CLLS: -88. 4%, EDIT: -90. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

08

What are the main differences between CLLS and EDIT?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: CLLS is a small-cap high-growth stock; EDIT is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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  • Market Cap > $100B
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