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Stock Comparison

CPRX vs PTCT

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
CPRX
Catalyst Pharmaceuticals, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$3.82B
5Y Perf.+623.1%
PTCT
PTC Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$5.35B
5Y Perf.+27.2%

CPRX vs PTCT — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
CPRX logoCPRX
PTCT logoPTCT
IndustryBiotechnologyBiotechnology
Market Cap$3.82B$5.35B
Revenue (TTM)$589M$827M
Net Income (TTM)$214M$-187M
Gross Margin85.2%49.7%
Operating Margin43.8%-8.3%
Forward P/E16.6x8.3x
Total Debt$2M$492M
Cash & Equiv.$709M$985M

CPRX vs PTCTLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

CPRX
PTCT
StockMay 20May 26Return
Catalyst Pharmaceut… (CPRX)100723.1+623.1%
PTC Therapeutics, I… (PTCT)100127.2+27.2%

Price return only. Dividends and distributions are not included.

Quick Verdict: CPRX vs PTCT

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: CPRX and PTCT are tied at the top with 3 categories each — the right choice depends on your priorities. PTC Therapeutics, Inc. is the stronger pick specifically for growth and revenue expansion and valuation and capital efficiency. As sector peers, any of these can serve as alternatives in the same allocation.
CPRX
Catalyst Pharmaceuticals, Inc.
The Income Pick

CPRX has the current edge in this matchup, primarily because of its strength in income & stability and long-term compounding.

  • beta 0.88
  • 48.0% 10Y total return vs PTCT's 7.3%
  • Lower volatility, beta 0.88, Low D/E 0.2%, current ratio 6.08x
Best for: income & stability and long-term compounding
PTCT
PTC Therapeutics, Inc.
The Growth Play

PTCT is the clearest fit if your priority is growth exposure.

  • Rev growth 114.5%, EPS growth 264.5%, 3Y rev CAGR 35.3%
  • 114.5% revenue growth vs CPRX's 19.8%
  • Lower P/E (8.3x vs 16.6x)
Best for: growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthPTCT logoPTCT114.5% revenue growth vs CPRX's 19.8%
ValuePTCT logoPTCTLower P/E (8.3x vs 16.6x)
Quality / MarginsCPRX logoCPRX36.4% margin vs PTCT's -22.6%
Stability / SafetyCPRX logoCPRXBeta 0.88 vs PTCT's 1.13
DividendsTieNeither stock pays a meaningful dividend
Momentum (1Y)PTCT logoPTCT+58.2% vs CPRX's +32.8%
Efficiency (ROA)CPRX logoCPRX19.4% ROA vs PTCT's -6.8%

CPRX vs PTCT — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

CPRXCatalyst Pharmaceuticals, Inc.
FY 2025
Product Revenue Net
100.0%$589M
License And Other Revenue
0.0%$182,000
PTCTPTC Therapeutics, Inc.
FY 2025
Collaboration and License Revenue
54.6%$998M
Product
32.1%$587M
Royalty
13.4%$244M

CPRX vs PTCT — Financial Metrics

Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLCPRXLAGGINGPTCT

Income & Cash Flow (Last 12 Months)

CPRX leads this category, winning 6 of 6 comparable metrics.

PTCT and CPRX operate at a comparable scale, with $827M and $589M in trailing revenue. CPRX is the more profitable business, keeping 36.4% of every revenue dollar as net income compared to PTCT's -22.6%. On growth, CPRX holds the edge at +7.6% YoY revenue growth, suggesting stronger near-term business momentum.

MetricCPRX logoCPRXCatalyst Pharmace…PTCT logoPTCTPTC Therapeutics,…
RevenueTrailing 12 months$589M$827M
EBITDAEarnings before interest/tax$295M-$37M
Net IncomeAfter-tax profit$214M-$187M
Free Cash FlowCash after capex$209M-$229M
Gross MarginGross profit ÷ Revenue+85.2%+49.7%
Operating MarginEBIT ÷ Revenue+43.8%-8.3%
Net MarginNet income ÷ Revenue+36.4%-22.6%
FCF MarginFCF ÷ Revenue+35.4%-27.7%
Rev. Growth (YoY)Latest quarter vs prior year+7.6%-76.8%
EPS Growth (YoY)Latest quarter vs prior year-9.1%-100.3%
CPRX leads this category, winning 6 of 6 comparable metrics.

Valuation Metrics

PTCT leads this category, winning 4 of 4 comparable metrics.

At 8.3x trailing earnings, PTCT trades at a 55% valuation discount to CPRX's 18.6x P/E. On an enterprise value basis, PTCT's 5.4x EV/EBITDA is more attractive than CPRX's 10.5x.

MetricCPRX logoCPRXCatalyst Pharmace…PTCT logoPTCTPTC Therapeutics,…
Market CapShares × price$3.8B$5.3B
Enterprise ValueMkt cap + debt − cash$3.1B$4.9B
Trailing P/EPrice ÷ TTM EPS18.55x8.29x
Forward P/EPrice ÷ next-FY EPS est.16.58x
PEG RatioP/E ÷ EPS growth rate0.99x
EV / EBITDAEnterprise value multiple10.54x5.42x
Price / SalesMarket cap ÷ Revenue6.48x3.09x
Price / BookPrice ÷ Book value/share4.16x
Price / FCFMarket cap ÷ FCF18.30x7.61x
PTCT leads this category, winning 4 of 4 comparable metrics.

Profitability & Efficiency

CPRX leads this category, winning 3 of 5 comparable metrics.

On the Piotroski fundamental quality scale (0–9), PTCT scores 7/9 vs CPRX's 4/9, reflecting strong financial health.

MetricCPRX logoCPRXCatalyst Pharmace…PTCT logoPTCTPTC Therapeutics,…
ROE (TTM)Return on equity+22.5%
ROA (TTM)Return on assets+19.4%-6.8%
ROICReturn on invested capital+83.9%
ROCEReturn on capital employed+30.6%+55.9%
Piotroski ScoreFundamental quality 0–947
Debt / EquityFinancial leverage0.00x
Net DebtTotal debt minus cash-$707M-$492M
Cash & Equiv.Liquid assets$709M$985M
Total DebtShort + long-term debt$2M$492M
Interest CoverageEBIT ÷ Interest expense-1.67x
CPRX leads this category, winning 3 of 5 comparable metrics.

Total Returns (Dividends Reinvested)

CPRX leads this category, winning 5 of 6 comparable metrics.

A $10,000 investment in CPRX five years ago would be worth $64,524 today (with dividends reinvested), compared to $16,026 for PTCT. Over the past 12 months, PTCT leads with a +58.2% total return vs CPRX's +32.8%. The 3-year compound annual growth rate (CAGR) favors CPRX at 21.5% vs PTCT's 5.1% — a key indicator of consistent wealth creation.

MetricCPRX logoCPRXCatalyst Pharmace…PTCT logoPTCTPTC Therapeutics,…
YTD ReturnYear-to-date+34.6%-16.0%
1-Year ReturnPast 12 months+32.8%+58.2%
3-Year ReturnCumulative with dividends+79.4%+16.1%
5-Year ReturnCumulative with dividends+545.2%+60.3%
10-Year ReturnCumulative with dividends+4800.2%+733.2%
CAGR (3Y)Annualised 3-year return+21.5%+5.1%
CPRX leads this category, winning 5 of 6 comparable metrics.

Risk & Volatility

CPRX leads this category, winning 2 of 2 comparable metrics.

CPRX is the less volatile stock with a 0.88 beta — it tends to amplify market swings less than PTCT's 1.13 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. CPRX currently trades 95.7% from its 52-week high vs PTCT's 73.7% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricCPRX logoCPRXCatalyst Pharmace…PTCT logoPTCTPTC Therapeutics,…
Beta (5Y)Sensitivity to S&P 5000.88x1.13x
52-Week HighHighest price in past year$32.56$87.50
52-Week LowLowest price in past year$19.05$37.94
% of 52W HighCurrent price vs 52-week peak+95.7%+73.7%
RSI (14)Momentum oscillator 0–10071.345.3
Avg Volume (50D)Average daily shares traded1.7M1.0M
CPRX leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Wall Street rates CPRX as "Buy" and PTCT as "Buy". Consensus price targets imply 39.0% upside for PTCT (target: $90) vs 5.9% for CPRX (target: $33).

MetricCPRX logoCPRXCatalyst Pharmace…PTCT logoPTCTPTC Therapeutics,…
Analyst RatingConsensus buy/hold/sellBuyBuy
Price TargetConsensus 12-month target$33.00$89.67
# AnalystsCovering analysts1626
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap+0.7%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

CPRX leads in 4 of 6 categories (Income & Cash Flow, Profitability & Efficiency). PTCT leads in 1 (Valuation Metrics).

Best OverallCatalyst Pharmaceuticals, I… (CPRX)Leads 4 of 6 categories
Loading custom metrics...

CPRX vs PTCT: Frequently Asked Questions

10 questions · data-driven answers · updated daily

01

Is CPRX or PTCT a better buy right now?

For growth investors, PTC Therapeutics, Inc.

(PTCT) is the stronger pick with 114. 5% revenue growth year-over-year, versus 19. 8% for Catalyst Pharmaceuticals, Inc. (CPRX). PTC Therapeutics, Inc. (PTCT) offers the better valuation at 8. 3x trailing P/E, making it the more compelling value choice. Analysts rate Catalyst Pharmaceuticals, Inc. (CPRX) a "Buy" — based on 16 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — CPRX or PTCT?

On trailing P/E, PTC Therapeutics, Inc.

(PTCT) is the cheapest at 8. 3x versus Catalyst Pharmaceuticals, Inc. at 18. 6x.

03

Which is the better long-term investment — CPRX or PTCT?

Over the past 5 years, Catalyst Pharmaceuticals, Inc.

(CPRX) delivered a total return of +545. 2%, compared to +60. 3% for PTC Therapeutics, Inc. (PTCT). Over 10 years, the gap is even starker: CPRX returned +48. 0% versus PTCT's +733. 2%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — CPRX or PTCT?

By beta (market sensitivity over 5 years), Catalyst Pharmaceuticals, Inc.

(CPRX) is the lower-risk stock at 0. 88β versus PTC Therapeutics, Inc. 's 1. 13β — meaning PTCT is approximately 28% more volatile than CPRX relative to the S&P 500.

05

Which is growing faster — CPRX or PTCT?

By revenue growth (latest reported year), PTC Therapeutics, Inc.

(PTCT) is pulling ahead at 114. 5% versus 19. 8% for Catalyst Pharmaceuticals, Inc. (CPRX). On earnings-per-share growth, the picture is similar: PTC Therapeutics, Inc. grew EPS 264. 5% year-over-year, compared to 28. 2% for Catalyst Pharmaceuticals, Inc.. Over a 3-year CAGR, CPRX leads at 40. 1% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — CPRX or PTCT?

PTC Therapeutics, Inc.

(PTCT) is the more profitable company, earning 39. 4% net margin versus 36. 4% for Catalyst Pharmaceuticals, Inc. — meaning it keeps 39. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: PTCT leads at 49. 5% versus 43. 8% for CPRX. At the gross margin level — before operating expenses — PTCT leads at 95. 9%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is CPRX or PTCT more undervalued right now?

Analyst consensus price targets imply the most upside for PTCT: 39.

0% to $89. 67.

08

Which pays a better dividend — CPRX or PTCT?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

09

Is CPRX or PTCT better for a retirement portfolio?

For long-horizon retirement investors, PTC Therapeutics, Inc.

(PTCT) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 13), +733. 2% 10Y return). Both have compounded well over 10 years (PTCT: +733. 2%, CPRX: +48. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between CPRX and PTCT?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

Find Stocks Like These

Explore pre-built screens for each stock's profile, or build a custom screen to find stocks that outperform both.

Stocks Like

CPRX

Quality Mega-Cap Compounder

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 5%
  • Net Margin > 21%
Run This Screen
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PTCT

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 29%
Run This Screen
Custom Screen

Beat Both

Find stocks that outperform CPRX and PTCT on the metrics below

Revenue Growth>
%
(CPRX: 7.6% · PTCT: -76.8%)
P/E Ratio<
x
(CPRX: 18.6x · PTCT: 8.3x)

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