Biotechnology
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CUE vs DBVT vs ALKS vs IMVT vs REGN
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
Biotechnology
CUE vs DBVT vs ALKS vs IMVT vs REGN — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $94M | $1712.35T | $5.90B | $5.53B | $73.68B |
| Revenue (TTM) | $27M | $0.00 | $1.56B | $0.00 | $14.92B |
| Net Income (TTM) | $-27M | $-168M | $153M | $-464M | $4.42B |
| Gross Margin | 88.0% | — | 65.4% | — | 84.5% |
| Operating Margin | -96.6% | — | 12.3% | — | 24.3% |
| Forward P/E | — | — | 24.8x | — | 15.3x |
| Total Debt | $4M | $22M | $70M | $98K | $2.71B |
| Cash & Equiv. | $27M | $194M | $1.12B | $714M | $3.12B |
CUE vs DBVT vs ALKS vs IMVT vs REGN — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Cue Biopharma, Inc. (CUE) | 100 | 4.3 | -95.7% |
| DBV Technologies S.… (DBVT) | 100 | 41.2 | -58.8% |
| Alkermes plc (ALKS) | 100 | 216.4 | +116.4% |
| Immunovant, Inc. (IMVT) | 100 | 106.1 | +6.1% |
| Regeneron Pharmaceu… (REGN) | 100 | 115.7 | +15.7% |
Price return only. Dividends and distributions are not included.
Quick Verdict: CUE vs DBVT vs ALKS vs IMVT vs REGN
Each card shows where this stock fits in a portfolio — not just who wins on paper.
CUE is the #2 pick in this set and the best alternative if growth exposure is your priority.
- Rev growth 195.7%, EPS growth 61.1%, 3Y rev CAGR 180.5%
- 195.7% revenue growth vs DBVT's -100.0%
DBVT ranks third and is worth considering specifically for momentum.
- +110.4% vs ALKS's +16.5%
ALKS lags the leaders in this set but could rank higher in a more targeted comparison.
IMVT is the clearest fit if your priority is long-term compounding.
- 173.6% 10Y total return vs REGN's 90.0%
REGN carries the broadest edge in this set and is the clearest fit for income & stability and sleep-well-at-night.
- Dividend streak 1 yrs, beta 0.81, yield 0.5%
- Lower volatility, beta 0.81, Low D/E 8.7%, current ratio 4.13x
- Beta 0.81, yield 0.5%, current ratio 4.13x
- Better valuation composite
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 195.7% revenue growth vs DBVT's -100.0% | |
| Value | Better valuation composite | |
| Quality / Margins | 29.6% margin vs CUE's -96.9% | |
| Stability / Safety | Beta 0.81 vs CUE's 2.34, lower leverage | |
| Dividends | 0.5% yield; 1-year raise streak; the other 4 pay no meaningful dividend | |
| Momentum (1Y) | +110.4% vs ALKS's +16.5% | |
| Efficiency (ROA) | 11.1% ROA vs DBVT's -89.0% |
CUE vs DBVT vs ALKS vs IMVT vs REGN — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
Segment breakdown not available.
CUE vs DBVT vs ALKS vs IMVT vs REGN — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
ALKS leads in 2 of 6 categories
IMVT leads 1 • REGN leads 1 • CUE leads 0 • DBVT leads 0 • 2 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
Evenly matched — CUE and REGN each lead in 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
REGN and IMVT operate at a comparable scale, with $14.9B and $0 in trailing revenue. REGN is the more profitable business, keeping 29.6% of every revenue dollar as net income compared to CUE's -96.9%. On growth, CUE holds the edge at +12.9% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $27M | $0 | $1.6B | $0 | $14.9B |
| EBITDAEarnings before interest/tax | -$23M | -$112M | $212M | -$487M | $4.2B |
| Net IncomeAfter-tax profit | -$27M | -$168M | $153M | -$464M | $4.4B |
| Free Cash FlowCash after capex | -$22M | -$151M | $392M | -$423M | $4.2B |
| Gross MarginGross profit ÷ Revenue | +88.0% | — | +65.4% | — | +84.5% |
| Operating MarginEBIT ÷ Revenue | -96.6% | — | +12.3% | — | +24.3% |
| Net MarginNet income ÷ Revenue | -96.9% | — | +9.8% | — | +29.6% |
| FCF MarginFCF ÷ Revenue | -79.6% | — | +25.1% | — | +27.9% |
| Rev. Growth (YoY)Latest quarter vs prior year | +12.9% | — | +28.2% | — | +19.0% |
| EPS Growth (YoY)Latest quarter vs prior year | +111.0% | +91.5% | -4.1% | +19.7% | -7.2% |
Valuation Metrics
ALKS leads this category, winning 2 of 5 comparable metrics.
Valuation Metrics
At 17.1x trailing earnings, REGN trades at a 31% valuation discount to ALKS's 24.8x P/E. On an enterprise value basis, ALKS's 17.3x EV/EBITDA is more attractive than REGN's 17.8x.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $94M | $1712.35T | $5.9B | $5.5B | $73.7B |
| Enterprise ValueMkt cap + debt − cash | $71M | $1712.35T | $4.9B | $4.8B | $73.3B |
| Trailing P/EPrice ÷ TTM EPS | -4.25x | -0.76x | 24.76x | -9.97x | 17.09x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — | 15.35x |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — | 2.70x |
| EV / EBITDAEnterprise value multiple | — | — | 17.25x | — | 17.78x |
| Price / SalesMarket cap ÷ Revenue | 3.42x | — | 4.00x | — | 5.14x |
| Price / BookPrice ÷ Book value/share | 4.27x | 0.66x | 3.28x | 5.83x | 2.46x |
| Price / FCFMarket cap ÷ FCF | — | — | 12.28x | — | 18.06x |
Profitability & Efficiency
ALKS leads this category, winning 4 of 9 comparable metrics.
Profitability & Efficiency
REGN delivers a 14.3% return on equity — every $100 of shareholder capital generates $14 in annual profit, vs $-165 for CUE. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to CUE's 0.16x. On the Piotroski fundamental quality scale (0–9), ALKS scores 7/9 vs IMVT's 2/9, reflecting strong financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -165.2% | -130.2% | +8.8% | -47.1% | +14.3% |
| ROA (TTM)Return on assets | -77.8% | -89.0% | +5.4% | -44.1% | +11.1% |
| ROICReturn on invested capital | -5.4% | — | +18.9% | — | +8.9% |
| ROCEReturn on capital employed | -112.5% | -145.7% | +14.2% | -66.1% | +10.2% |
| Piotroski ScoreFundamental quality 0–9 | 5 | 4 | 7 | 2 | 5 |
| Debt / EquityFinancial leverage | 0.16x | 0.13x | 0.04x | 0.00x | 0.09x |
| Net DebtTotal debt minus cash | -$23M | -$172M | -$1.0B | -$714M | -$412M |
| Cash & Equiv.Liquid assets | $27M | $194M | $1.1B | $714M | $3.1B |
| Total DebtShort + long-term debt | $4M | $22M | $70M | $98,000 | $2.7B |
| Interest CoverageEBIT ÷ Interest expense | -74.29x | -189.82x | 32.30x | — | 108.44x |
Total Returns (Dividends Reinvested)
IMVT leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in IMVT five years ago would be worth $16,241 today (with dividends reinvested), compared to $1,058 for CUE. Over the past 12 months, DBVT leads with a +110.4% total return vs ALKS's +16.5%. The 3-year compound annual growth rate (CAGR) favors IMVT at 12.1% vs CUE's -37.6% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | +253.1% | +4.9% | +25.3% | +5.1% | -8.5% |
| 1-Year ReturnPast 12 months | +55.0% | +110.4% | +16.5% | +96.1% | +27.1% |
| 3-Year ReturnCumulative with dividends | -75.7% | +19.7% | +14.5% | +40.9% | -5.1% |
| 5-Year ReturnCumulative with dividends | -89.4% | -69.1% | +60.9% | +62.4% | +43.6% |
| 10-Year ReturnCumulative with dividends | -89.8% | -87.0% | -11.0% | +173.6% | +90.0% |
| CAGR (3Y)Annualised 3-year return | -37.6% | +6.2% | +4.6% | +12.1% | -1.7% |
Risk & Volatility
Evenly matched — ALKS and REGN each lead in 1 of 2 comparable metrics.
Risk & Volatility
REGN is the less volatile stock with a 0.81 beta — it tends to amplify market swings less than CUE's 2.34 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ALKS currently trades 96.7% from its 52-week high vs DBVT's 76.3% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 2.34x | 1.26x | 1.06x | 1.37x | 0.81x |
| 52-Week HighHighest price in past year | $41.42 | $26.18 | $36.60 | $30.09 | $821.11 |
| 52-Week LowLowest price in past year | $0.35 | $7.53 | $25.17 | $13.36 | $476.49 |
| % of 52W HighCurrent price vs 52-week peak | +86.3% | +76.3% | +96.7% | +90.5% | +86.4% |
| RSI (14)Momentum oscillator 0–100 | 70.8 | 48.1 | 60.2 | 60.2 | 44.9 |
| Avg Volume (50D)Average daily shares traded | 903K | 252K | 2.3M | 1.4M | 631K |
Analyst Outlook
REGN leads this category, winning 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: DBVT as "Buy", ALKS as "Buy", IMVT as "Buy", REGN as "Buy". Consensus price targets imply 131.8% upside for DBVT (target: $46) vs 22.1% for REGN (target: $866). REGN is the only dividend payer here at 0.48% yield — a key consideration for income-focused portfolios.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | — | $46.33 | $44.00 | $45.50 | $865.68 |
| # AnalystsCovering analysts | — | 15 | 28 | 23 | 48 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — | +0.5% |
| Dividend StreakConsecutive years of raises | — | 0 | 0 | — | 1 |
| Dividend / ShareAnnual DPS | — | — | — | — | $3.41 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | +0.5% | 0.0% | +5.4% |
ALKS leads in 2 of 6 categories (Valuation Metrics, Profitability & Efficiency). IMVT leads in 1 (Total Returns). 2 tied.
CUE vs DBVT vs ALKS vs IMVT vs REGN: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is CUE or DBVT or ALKS or IMVT or REGN a better buy right now?
For growth investors, Cue Biopharma, Inc.
(CUE) is the stronger pick with 195. 7% revenue growth year-over-year, versus -5. 2% for Alkermes plc (ALKS). Regeneron Pharmaceuticals, Inc. (REGN) offers the better valuation at 17. 1x trailing P/E (15. 3x forward), making it the more compelling value choice. Analysts rate DBV Technologies S. A. (DBVT) a "Buy" — based on 15 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — CUE or DBVT or ALKS or IMVT or REGN?
On trailing P/E, Regeneron Pharmaceuticals, Inc.
(REGN) is the cheapest at 17. 1x versus Alkermes plc at 24. 8x.
03Which is the better long-term investment — CUE or DBVT or ALKS or IMVT or REGN?
Over the past 5 years, Immunovant, Inc.
(IMVT) delivered a total return of +62. 4%, compared to -89. 4% for Cue Biopharma, Inc. (CUE). Over 10 years, the gap is even starker: IMVT returned +173. 6% versus CUE's -89. 8%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — CUE or DBVT or ALKS or IMVT or REGN?
By beta (market sensitivity over 5 years), Regeneron Pharmaceuticals, Inc.
(REGN) is the lower-risk stock at 0. 81β versus Cue Biopharma, Inc. 's 2. 34β — meaning CUE is approximately 190% more volatile than REGN relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 16% for Cue Biopharma, Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — CUE or DBVT or ALKS or IMVT or REGN?
By revenue growth (latest reported year), Cue Biopharma, Inc.
(CUE) is pulling ahead at 195. 7% versus -5. 2% for Alkermes plc (ALKS). On earnings-per-share growth, the picture is similar: Cue Biopharma, Inc. grew EPS 61. 1% year-over-year, compared to -347. 5% for DBV Technologies S. A.. Over a 3-year CAGR, CUE leads at 180. 5% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — CUE or DBVT or ALKS or IMVT or REGN?
Regeneron Pharmaceuticals, Inc.
(REGN) is the more profitable company, earning 31. 4% net margin versus -96. 9% for Cue Biopharma, Inc. — meaning it keeps 31. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: REGN leads at 24. 9% versus -96. 7% for CUE. At the gross margin level — before operating expenses — CUE leads at 87. 3%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is CUE or DBVT or ALKS or IMVT or REGN more undervalued right now?
Analyst consensus price targets imply the most upside for DBVT: 131.
8% to $46. 33.
08Which pays a better dividend — CUE or DBVT or ALKS or IMVT or REGN?
In this comparison, REGN (0.
5% yield) pays a dividend. CUE, DBVT, ALKS, IMVT do not pay a meaningful dividend and should not be held primarily for income.
09Is CUE or DBVT or ALKS or IMVT or REGN better for a retirement portfolio?
For long-horizon retirement investors, Regeneron Pharmaceuticals, Inc.
(REGN) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 81)). Cue Biopharma, Inc. (CUE) carries a higher beta of 2. 34 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (REGN: +90. 0%, CUE: -89. 8%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between CUE and DBVT and ALKS and IMVT and REGN?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: CUE is a small-cap high-growth stock; DBVT is a mega-cap quality compounder stock; ALKS is a small-cap quality compounder stock; IMVT is a small-cap quality compounder stock; REGN is a mid-cap deep-value stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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