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CVAC vs JNJ vs PFE vs ABT vs MRK

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
CVAC
CureVac N.V.

Biotechnology

HealthcareNASDAQ • DE
Market Cap$1.05B
5Y Perf.-91.5%
JNJ
Johnson & Johnson

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$536.23B
5Y Perf.+34.9%
PFE
Pfizer Inc.

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$150.63B
5Y Perf.-30.5%
ABT
Abbott Laboratories

Medical - Devices

HealthcareNYSE • US
Market Cap$151.30B
5Y Perf.+14.5%
MRK
Merck & Co., Inc.

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$277.34B
5Y Perf.+29.5%

CVAC vs JNJ vs PFE vs ABT vs MRK — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
CVAC logoCVAC
JNJ logoJNJ
PFE logoPFE
ABT logoABT
MRK logoMRK
IndustryBiotechnologyDrug Manufacturers - GeneralDrug Manufacturers - GeneralMedical - DevicesDrug Manufacturers - General
Market Cap$1.05B$536.23B$150.63B$151.30B$277.34B
Revenue (TTM)$511M$92.15B$63.31B$43.84B$64.93B
Net Income (TTM)$194M$25.12B$7.49B$13.98B$18.25B
Gross Margin94.8%68.1%69.3%54.0%74.2%
Operating Margin40.8%26.1%23.4%17.8%41.1%
Forward P/E6.5x19.2x8.9x15.9x21.9x
Total Debt$39M$36.63B$67.42B$15.28B$50.53B
Cash & Equiv.$482M$24.11B$1.14B$7.62B$14.56B

CVAC vs JNJ vs PFE vs ABT vs MRKLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

CVAC
JNJ
PFE
ABT
MRK
StockAug 20Jan 26Return
CureVac N.V. (CVAC)1008.5-91.5%
Johnson & Johnson (JNJ)100134.9+34.9%
Pfizer Inc. (PFE)10069.5-30.5%
Abbott Laboratories (ABT)100114.5+14.5%
Merck & Co., Inc. (MRK)100129.5+29.5%

Price return only. Dividends and distributions are not included.

Quick Verdict: CVAC vs JNJ vs PFE vs ABT vs MRK

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: CVAC leads in 4 of 7 categories (5-stock set), making it the strongest pick for growth and revenue expansion and valuation and capital efficiency. Johnson & Johnson is the stronger pick specifically for capital preservation and lower volatility. PFE and MRK also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
CVAC
CureVac N.V.
The Growth Play

CVAC carries the broadest edge in this set and is the clearest fit for growth exposure.

  • Rev growth 9.0%, EPS growth 161.0%, 3Y rev CAGR 73.2%
  • 9.0% revenue growth vs PFE's -1.6%
  • Lower P/E (6.5x vs 21.9x)
  • 37.9% margin vs PFE's 11.8%
Best for: growth exposure
JNJ
Johnson & Johnson
The Defensive Choice

JNJ is the #2 pick in this set and the best alternative if stability is your priority.

  • Beta 0.06 vs CVAC's 1.23
Best for: stability
PFE
Pfizer Inc.
The Income Pick

PFE ranks third and is worth considering specifically for income & stability.

  • Dividend streak 15 yrs, beta 0.54, yield 6.5%
  • 6.5% yield, 15-year raise streak, vs JNJ's 2.2%, (1 stock pays no dividend)
Best for: income & stability
ABT
Abbott Laboratories
The Defensive Pick

ABT is the clearest fit if your priority is sleep-well-at-night and valuation efficiency.

  • Lower volatility, beta 0.25, Low D/E 31.9%, current ratio 1.67x
  • PEG 0.53 vs JNJ's 34.17
  • Beta 0.25, yield 2.5%, current ratio 1.67x
Best for: sleep-well-at-night and valuation efficiency
MRK
Merck & Co., Inc.
The Long-Run Compounder

MRK is the clearest fit if your priority is long-term compounding.

  • 166.5% 10Y total return vs ABT's 173.7%
  • +46.1% vs ABT's -33.2%
Best for: long-term compounding
See the full category breakdown
CategoryWinnerWhy
GrowthCVAC logoCVAC9.0% revenue growth vs PFE's -1.6%
ValueCVAC logoCVACLower P/E (6.5x vs 21.9x)
Quality / MarginsCVAC logoCVAC37.9% margin vs PFE's 11.8%
Stability / SafetyJNJ logoJNJBeta 0.06 vs CVAC's 1.23
DividendsPFE logoPFE6.5% yield, 15-year raise streak, vs JNJ's 2.2%, (1 stock pays no dividend)
Momentum (1Y)MRK logoMRK+46.1% vs ABT's -33.2%
Efficiency (ROA)CVAC logoCVAC28.1% ROA vs PFE's 3.6%, ROIC 65.0% vs 7.5%

CVAC vs JNJ vs PFE vs ABT vs MRK — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

CVACCureVac N.V.
FY 2023
Product
50.2%$11M
Research and development services
49.8%$11M
JNJJohnson & Johnson
FY 2024
Innovative Medicine
64.1%$57.0B
MedTech
35.9%$31.9B
PFEPfizer Inc.
FY 2025
Biopharma Segment
97.8%$61.2B
Segment Reporting, Reconciling Item, Corporate Nonsegment
2.2%$1.4B
ABTAbbott Laboratories
FY 2024
Medical Devices
45.3%$19.0B
Diagnostic Products
22.3%$9.3B
Nutritional Products
20.1%$8.4B
Established Pharmaceutical Products
12.4%$5.2B
MRKMerck & Co., Inc.
FY 2025
Pharmaceutical segment
89.4%$58.1B
Animal Health segment
9.8%$6.4B
Other Segments
0.8%$515M

CVAC vs JNJ vs PFE vs ABT vs MRK — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLCVACLAGGINGMRK

Income & Cash Flow (Last 12 Months)

CVAC leads this category, winning 3 of 6 comparable metrics.

JNJ is the larger business by revenue, generating $92.1B annually — 180.5x CVAC's $511M. CVAC is the more profitable business, keeping 37.9% of every revenue dollar as net income compared to PFE's 11.8%. On growth, ABT holds the edge at +6.9% YoY revenue growth, suggesting stronger near-term business momentum.

MetricCVAC logoCVACCureVac N.V.JNJ logoJNJJohnson & JohnsonPFE logoPFEPfizer Inc.ABT logoABTAbbott Laboratori…MRK logoMRKMerck & Co., Inc.
RevenueTrailing 12 months$511M$92.1B$63.3B$43.8B$64.9B
EBITDAEarnings before interest/tax$226M$31.4B$21.0B$10.9B$32.4B
Net IncomeAfter-tax profit$194M$25.1B$7.5B$14.0B$18.3B
Free Cash FlowCash after capex$196M$19.1B$9.5B$6.9B$12.4B
Gross MarginGross profit ÷ Revenue+94.8%+68.1%+69.3%+54.0%+74.2%
Operating MarginEBIT ÷ Revenue+40.8%+26.1%+23.4%+17.8%+41.1%
Net MarginNet income ÷ Revenue+37.9%+27.3%+11.8%+31.9%+28.1%
FCF MarginFCF ÷ Revenue+38.4%+20.7%+15.0%+15.8%+19.0%
Rev. Growth (YoY)Latest quarter vs prior year-91.4%+6.8%+5.4%+6.9%+4.5%
EPS Growth (YoY)Latest quarter vs prior year+18.8%+91.0%-9.5%0.0%-19.6%
CVAC leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

CVAC leads this category, winning 5 of 7 comparable metrics.

At 6.5x trailing earnings, CVAC trades at a 83% valuation discount to JNJ's 38.4x P/E. Adjusting for growth (PEG ratio), ABT offers better value at 0.38x vs JNJ's 34.17x — a lower PEG means you pay less per unit of expected earnings growth.

MetricCVAC logoCVACCureVac N.V.JNJ logoJNJJohnson & JohnsonPFE logoPFEPfizer Inc.ABT logoABTAbbott Laboratori…MRK logoMRKMerck & Co., Inc.
Market CapShares × price$1.0B$536.2B$150.6B$151.3B$277.3B
Enterprise ValueMkt cap + debt − cash$607M$548.8B$216.9B$159.0B$313.3B
Trailing P/EPrice ÷ TTM EPS6.47x38.43x19.47x11.39x15.42x
Forward P/EPrice ÷ next-FY EPS est.19.20x8.94x15.87x21.93x
PEG RatioP/E ÷ EPS growth rate34.17x0.38x0.73x
EV / EBITDAEnterprise value multiple3.09x18.61x10.66x15.83x10.68x
Price / SalesMarket cap ÷ Revenue1.96x6.04x2.41x3.61x4.27x
Price / BookPrice ÷ Book value/share1.51x7.56x1.74x3.18x5.35x
Price / FCFMarket cap ÷ FCF12.58x27.02x16.60x23.82x22.44x
CVAC leads this category, winning 5 of 7 comparable metrics.

Profitability & Efficiency

CVAC leads this category, winning 8 of 9 comparable metrics.

MRK delivers a 36.1% return on equity — every $100 of shareholder capital generates $36 in annual profit, vs $8 for PFE. CVAC carries lower financial leverage with a 0.06x debt-to-equity ratio, signaling a more conservative balance sheet compared to MRK's 0.96x. On the Piotroski fundamental quality scale (0–9), CVAC scores 7/9 vs MRK's 4/9, reflecting strong financial health.

MetricCVAC logoCVACCureVac N.V.JNJ logoJNJJohnson & JohnsonPFE logoPFEPfizer Inc.ABT logoABTAbbott Laboratori…MRK logoMRKMerck & Co., Inc.
ROE (TTM)Return on equity+33.0%+31.7%+8.3%+27.3%+36.1%
ROA (TTM)Return on assets+28.1%+13.0%+3.6%+16.6%+14.6%
ROICReturn on invested capital+65.0%+20.7%+7.5%+9.9%+22.0%
ROCEReturn on capital employed+26.7%+17.6%+9.0%+10.8%+23.8%
Piotroski ScoreFundamental quality 0–975774
Debt / EquityFinancial leverage0.06x0.51x0.78x0.32x0.96x
Net DebtTotal debt minus cash-$443M$12.5B$66.3B$7.7B$36.0B
Cash & Equiv.Liquid assets$482M$24.1B$1.1B$7.6B$14.6B
Total DebtShort + long-term debt$39M$36.6B$67.4B$15.3B$50.5B
Interest CoverageEBIT ÷ Interest expense547.87x48.23x4.02x19.22x19.68x
CVAC leads this category, winning 8 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

JNJ leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in MRK five years ago would be worth $17,024 today (with dividends reinvested), compared to $464 for CVAC. Over the past 12 months, MRK leads with a +46.1% total return vs ABT's -33.2%. The 3-year compound annual growth rate (CAGR) favors JNJ at 13.5% vs CVAC's -18.0% — a key indicator of consistent wealth creation.

MetricCVAC logoCVACCureVac N.V.JNJ logoJNJJohnson & JohnsonPFE logoPFEPfizer Inc.ABT logoABTAbbott Laboratori…MRK logoMRKMerck & Co., Inc.
YTD ReturnYear-to-date-0.2%+7.9%+6.9%-28.9%+6.3%
1-Year ReturnPast 12 months+34.3%+44.8%+23.7%-33.2%+46.1%
3-Year ReturnCumulative with dividends-44.9%+46.3%-18.4%-15.4%+2.9%
5-Year ReturnCumulative with dividends-95.4%+46.1%-13.3%-17.9%+70.2%
10-Year ReturnCumulative with dividends-91.7%+132.3%+29.6%+173.7%+166.5%
CAGR (3Y)Annualised 3-year return-18.0%+13.5%-6.6%-5.4%+0.9%
JNJ leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

Evenly matched — JNJ and PFE each lead in 1 of 2 comparable metrics.

JNJ is the less volatile stock with a 0.06 beta — it tends to amplify market swings less than CVAC's 1.23 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. PFE currently trades 92.1% from its 52-week high vs ABT's 62.6% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricCVAC logoCVACCureVac N.V.JNJ logoJNJJohnson & JohnsonPFE logoPFEPfizer Inc.ABT logoABTAbbott Laboratori…MRK logoMRKMerck & Co., Inc.
Beta (5Y)Sensitivity to S&P 5001.23x0.06x0.54x0.25x0.48x
52-Week HighHighest price in past year$5.72$251.71$28.75$139.06$125.14
52-Week LowLowest price in past year$3.32$146.12$21.97$86.15$73.31
% of 52W HighCurrent price vs 52-week peak+81.5%+88.4%+92.1%+62.6%+89.7%
RSI (14)Momentum oscillator 0–10047.837.144.222.946.7
Avg Volume (50D)Average daily shares traded07.0M33.3M10.5M7.3M
Evenly matched — JNJ and PFE each lead in 1 of 2 comparable metrics.

Analyst Outlook

Evenly matched — JNJ and PFE each lead in 1 of 2 comparable metrics.

Analyst consensus: CVAC as "Hold", JNJ as "Buy", PFE as "Hold", ABT as "Buy", MRK as "Buy". Consensus price targets imply 350.6% upside for CVAC (target: $21) vs 3.0% for PFE (target: $27). For income investors, PFE offers the higher dividend yield at 6.49% vs JNJ's 2.19%.

MetricCVAC logoCVACCureVac N.V.JNJ logoJNJJohnson & JohnsonPFE logoPFEPfizer Inc.ABT logoABTAbbott Laboratori…MRK logoMRKMerck & Co., Inc.
Analyst RatingConsensus buy/hold/sellHoldBuyHoldBuyBuy
Price TargetConsensus 12-month target$21.00$249.27$27.27$128.71$129.31
# AnalystsCovering analysts840394137
Dividend YieldAnnual dividend ÷ price+2.2%+6.5%+2.5%+2.9%
Dividend StreakConsecutive years of raises36151114
Dividend / ShareAnnual DPS$4.87$1.72$2.19$3.26
Buyback YieldShare repurchases ÷ mkt cap0.0%+0.5%0.0%+0.9%+1.8%
Evenly matched — JNJ and PFE each lead in 1 of 2 comparable metrics.
Key Takeaway

CVAC leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). JNJ leads in 1 (Total Returns). 2 tied.

Best OverallCureVac N.V. (CVAC)Leads 3 of 6 categories
Loading custom metrics...

CVAC vs JNJ vs PFE vs ABT vs MRK: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is CVAC or JNJ or PFE or ABT or MRK a better buy right now?

For growth investors, CureVac N.

V. (CVAC) is the stronger pick with 895. 5% revenue growth year-over-year, versus -1. 6% for Pfizer Inc. (PFE). CureVac N. V. (CVAC) offers the better valuation at 6. 5x trailing P/E, making it the more compelling value choice. Analysts rate Johnson & Johnson (JNJ) a "Buy" — based on 40 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — CVAC or JNJ or PFE or ABT or MRK?

On trailing P/E, CureVac N.

V. (CVAC) is the cheapest at 6. 5x versus Johnson & Johnson at 38. 4x. On forward P/E, Pfizer Inc. is actually cheaper at 8. 9x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Abbott Laboratories wins at 0. 53x versus Johnson & Johnson's 34. 17x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.

03

Which is the better long-term investment — CVAC or JNJ or PFE or ABT or MRK?

Over the past 5 years, Merck & Co.

, Inc. (MRK) delivered a total return of +70. 2%, compared to -95. 4% for CureVac N. V. (CVAC). Over 10 years, the gap is even starker: ABT returned +173. 7% versus CVAC's -91. 7%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — CVAC or JNJ or PFE or ABT or MRK?

By beta (market sensitivity over 5 years), Johnson & Johnson (JNJ) is the lower-risk stock at 0.

06β versus CureVac N. V. 's 1. 23β — meaning CVAC is approximately 2064% more volatile than JNJ relative to the S&P 500. On balance sheet safety, CureVac N. V. (CVAC) carries a lower debt/equity ratio of 6% versus 96% for Merck & Co. , Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — CVAC or JNJ or PFE or ABT or MRK?

By revenue growth (latest reported year), CureVac N.

V. (CVAC) is pulling ahead at 895. 5% versus -1. 6% for Pfizer Inc. (PFE). On earnings-per-share growth, the picture is similar: CureVac N. V. grew EPS 161. 0% year-over-year, compared to -57. 8% for Johnson & Johnson. Over a 3-year CAGR, CVAC leads at 73. 2% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — CVAC or JNJ or PFE or ABT or MRK?

Abbott Laboratories (ABT) is the more profitable company, earning 31.

9% net margin versus 12. 4% for Pfizer Inc. — meaning it keeps 31. 9% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: MRK leads at 36. 2% versus 16. 3% for ABT. At the gross margin level — before operating expenses — CVAC leads at 80. 2%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is CVAC or JNJ or PFE or ABT or MRK more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, Abbott Laboratories (ABT) is the more undervalued stock at a PEG of 0. 53x versus Johnson & Johnson's 34. 17x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Pfizer Inc. (PFE) trades at 8. 9x forward P/E versus 21. 9x for Merck & Co. , Inc. — 13. 0x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for CVAC: 350. 6% to $21. 00.

08

Which pays a better dividend — CVAC or JNJ or PFE or ABT or MRK?

In this comparison, PFE (6.

5% yield), MRK (2. 9% yield), ABT (2. 5% yield), JNJ (2. 2% yield) pay a dividend. CVAC does not pay a meaningful dividend and should not be held primarily for income.

09

Is CVAC or JNJ or PFE or ABT or MRK better for a retirement portfolio?

For long-horizon retirement investors, Johnson & Johnson (JNJ) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

06), 2. 2% yield, +132. 3% 10Y return). Both have compounded well over 10 years (JNJ: +132. 3%, CVAC: -91. 7%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between CVAC and JNJ and PFE and ABT and MRK?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: CVAC is a small-cap high-growth stock; JNJ is a large-cap quality compounder stock; PFE is a mid-cap income-oriented stock; ABT is a mid-cap deep-value stock; MRK is a large-cap deep-value stock. JNJ, PFE, ABT, MRK pay a dividend while CVAC does not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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CVAC

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  • Sector: Healthcare
  • Market Cap > $100B
  • Net Margin > 22%
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JNJ

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  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 5%
  • Net Margin > 16%
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PFE

Income & Dividend Stock

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 5%
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ABT

Dividend Mega-Cap Quality

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 5%
  • Net Margin > 19%
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MRK

Dividend Mega-Cap Quality

  • Sector: Healthcare
  • Market Cap > $100B
  • Net Margin > 16%
  • Dividend Yield > 1.1%
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Custom Screen

Beat Both

Find stocks that outperform CVAC and JNJ and PFE and ABT and MRK on the metrics below

Revenue Growth>
%
(CVAC: -91.4% · JNJ: 6.8%)
Net Margin>
%
(CVAC: 37.9% · JNJ: 27.3%)
P/E Ratio<
x
(CVAC: 6.5x · JNJ: 38.4x)

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