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CYRX vs IART vs HOLX vs LQDA vs BDX

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
CYRX
Cryoport, Inc.

Integrated Freight & Logistics

IndustrialsNASDAQ • US
Market Cap$641M
5Y Perf.-44.6%
IART
Integra LifeSciences Holdings Corporation

Medical - Devices

HealthcareNASDAQ • US
Market Cap$1.06B
5Y Perf.-73.3%
HOLX
Hologic, Inc.

Medical - Instruments & Supplies

HealthcareNASDAQ • US
Market Cap$16.97B
5Y Perf.+42.6%
LQDA
Liquidia Corporation

Biotechnology

HealthcareNASDAQ • US
Market Cap$3.67B
5Y Perf.+358.7%
BDX
Becton, Dickinson and Company

Medical - Instruments & Supplies

HealthcareNYSE • US
Market Cap$55.53B
5Y Perf.+0.4%

CYRX vs IART vs HOLX vs LQDA vs BDX — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
CYRX logoCYRX
IART logoIART
HOLX logoHOLX
LQDA logoLQDA
BDX logoBDX
IndustryIntegrated Freight & LogisticsMedical - DevicesMedical - Instruments & SuppliesBiotechnologyMedical - Instruments & Supplies
Market Cap$641M$1.06B$16.97B$3.67B$55.53B
Revenue (TTM)$183M$1.64B$4.13B$69M$21.36B
Net Income (TTM)$77M$-496M$544M$-122M$1.14B
Gross Margin47.2%39.6%52.8%89.4%46.5%
Operating Margin-20.2%5.8%17.5%-155.0%10.6%
Forward P/E9.1x5.8x17.2x17.6x11.9x
Total Debt$231M$2.03B$2.63B$122M$19.18B
Cash & Equiv.$250M$235M$1.96B$176M$851M

CYRX vs IART vs HOLX vs LQDA vs BDXLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

CYRX
IART
HOLX
LQDA
BDX
StockMay 20May 26Return
Cryoport, Inc. (CYRX)10055.4-44.6%
Integra LifeScience… (IART)10026.7-73.3%
Hologic, Inc. (HOLX)100142.6+42.6%
Liquidia Corporation (LQDA)100458.7+358.7%
Becton, Dickinson a… (BDX)100100.4+0.4%

Price return only. Dividends and distributions are not included.

Quick Verdict: CYRX vs IART vs HOLX vs LQDA vs BDX

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: CYRX and BDX are tied at the top with 2 categories each (5-stock set) — the right choice depends on your priorities. Becton, Dickinson and Company is the stronger pick specifically for growth and revenue expansion and dividend income and shareholder returns. IART, HOLX, and LQDA also each lead in at least one category. This set spans 2 sectors — these stocks serve different portfolio roles, not just different price points.
CYRX
Cryoport, Inc.
The Quality Compounder

CYRX has the current edge in this matchup, primarily because of its strength in quality and efficiency.

  • 42.2% margin vs LQDA's -176.0%
  • 10.3% ROA vs LQDA's -44.2%, ROIC -5.1% vs -5.0%
Best for: quality and efficiency
IART
Integra LifeSciences Holdings Corporation
The Value Play

IART ranks third and is worth considering specifically for value.

  • Lower P/E (5.8x vs 11.9x)
Best for: value
HOLX
Hologic, Inc.
The Defensive Pick

HOLX is the clearest fit if your priority is sleep-well-at-night and defensive.

  • Lower volatility, beta 0.41, Low D/E 52.0%, current ratio 3.75x
  • Beta 0.41, current ratio 3.75x
  • Beta 0.41 vs IART's 2.34, lower leverage
Best for: sleep-well-at-night and defensive
LQDA
Liquidia Corporation
The Long-Run Compounder

LQDA is the clearest fit if your priority is long-term compounding.

  • 280.9% 10Y total return vs CYRX's 5.6%
  • +172.2% vs IART's +6.5%
Best for: long-term compounding
BDX
Becton, Dickinson and Company
The Income Pick

BDX is the #2 pick in this set and the best alternative if income & stability and growth exposure is your priority.

  • Dividend streak 1 yrs, beta 0.66, yield 2.7%
  • Rev growth 8.2%, EPS growth -0.5%, 3Y rev CAGR 5.0%
  • 8.2% revenue growth vs CYRX's -24.5%
  • 2.7% yield; 1-year raise streak; the other 4 pay no meaningful dividend
Best for: income & stability and growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthBDX logoBDX8.2% revenue growth vs CYRX's -24.5%
ValueIART logoIARTLower P/E (5.8x vs 11.9x)
Quality / MarginsCYRX logoCYRX42.2% margin vs LQDA's -176.0%
Stability / SafetyHOLX logoHOLXBeta 0.41 vs IART's 2.34, lower leverage
DividendsBDX logoBDX2.7% yield; 1-year raise streak; the other 4 pay no meaningful dividend
Momentum (1Y)LQDA logoLQDA+172.2% vs IART's +6.5%
Efficiency (ROA)CYRX logoCYRX10.3% ROA vs LQDA's -44.2%, ROIC -5.1% vs -5.0%

CYRX vs IART vs HOLX vs LQDA vs BDX — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

CYRXCryoport, Inc.
FY 2025
Service
54.8%$96M
Product
45.2%$80M
IARTIntegra LifeSciences Holdings Corporation
FY 2025
Codman Specialty Surgical
73.4%$1.2B
Tissue Technologies
26.6%$435M
HOLXHologic, Inc.
FY 2025
Diagnostics
44.6%$1.8B
Breast Health
36.2%$1.5B
Gyn Surgical
16.6%$680M
Skeletal Health
2.7%$109M
LQDALiquidia Corporation
FY 2020
Promotion Agreement
100.0%$739,628
Research and Development Services
0.0%$0
BDXBecton, Dickinson and Company
FY 2025
Medical
52.5%$11.5B
Interventional
23.9%$5.2B
Life Sciences
23.7%$5.2B

CYRX vs IART vs HOLX vs LQDA vs BDX — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLHOLXLAGGINGBDX

Income & Cash Flow (Last 12 Months)

LQDA leads this category, winning 3 of 6 comparable metrics.

BDX is the larger business by revenue, generating $21.4B annually — 308.7x LQDA's $69M. CYRX is the more profitable business, keeping 42.2% of every revenue dollar as net income compared to LQDA's -176.0%. On growth, LQDA holds the edge at +11.2% YoY revenue growth, suggesting stronger near-term business momentum.

MetricCYRX logoCYRXCryoport, Inc.IART logoIARTIntegra LifeScien…HOLX logoHOLXHologic, Inc.LQDA logoLQDALiquidia Corporat…BDX logoBDXBecton, Dickinson…
RevenueTrailing 12 months$183M$1.6B$4.1B$69M$21.4B
EBITDAEarnings before interest/tax-$10M$209M$974M-$106M$4.2B
Net IncomeAfter-tax profit$77M-$496M$544M-$122M$1.1B
Free Cash FlowCash after capex-$18M-$10M$1000M-$108M$3.1B
Gross MarginGross profit ÷ Revenue+47.2%+39.6%+52.8%+89.4%+46.5%
Operating MarginEBIT ÷ Revenue-20.2%+5.8%+17.5%-155.0%+10.6%
Net MarginNet income ÷ Revenue+42.2%-30.1%+13.2%-176.0%+5.3%
FCF MarginFCF ÷ Revenue-9.7%-0.6%+24.2%-155.8%+14.7%
Rev. Growth (YoY)Latest quarter vs prior year+16.5%+2.4%+2.5%+11.2%-10.6%
EPS Growth (YoY)Latest quarter vs prior year+10.7%+81.8%-9.2%+86.4%-2.0%
LQDA leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

IART leads this category, winning 4 of 6 comparable metrics.

At 9.1x trailing earnings, CYRX trades at a 70% valuation discount to HOLX's 30.5x P/E. On an enterprise value basis, IART's 13.0x EV/EBITDA is more attractive than HOLX's 17.4x.

MetricCYRX logoCYRXCryoport, Inc.IART logoIARTIntegra LifeScien…HOLX logoHOLXHologic, Inc.LQDA logoLQDALiquidia Corporat…BDX logoBDXBecton, Dickinson…
Market CapShares × price$641M$1.1B$17.0B$3.7B$55.5B
Enterprise ValueMkt cap + debt − cash$621M$2.9B$17.6B$3.6B$73.9B
Trailing P/EPrice ÷ TTM EPS9.11x-2.01x30.53x-25.47x26.29x
Forward P/EPrice ÷ next-FY EPS est.5.77x17.21x17.58x11.90x
PEG RatioP/E ÷ EPS growth rate1.59x
EV / EBITDAEnterprise value multiple13.01x17.39x14.65x
Price / SalesMarket cap ÷ Revenue3.64x0.65x4.14x262.27x2.54x
Price / BookPrice ÷ Book value/share1.27x1.00x3.43x43.06x1.73x
Price / FCFMarket cap ÷ FCF18.44x20.80x
IART leads this category, winning 4 of 6 comparable metrics.

Profitability & Efficiency

HOLX leads this category, winning 4 of 9 comparable metrics.

CYRX delivers a 16.2% return on equity — every $100 of shareholder capital generates $16 in annual profit, vs $-6 for LQDA. CYRX carries lower financial leverage with a 0.46x debt-to-equity ratio, signaling a more conservative balance sheet compared to IART's 1.95x. On the Piotroski fundamental quality scale (0–9), HOLX scores 7/9 vs LQDA's 1/9, reflecting strong financial health.

MetricCYRX logoCYRXCryoport, Inc.IART logoIARTIntegra LifeScien…HOLX logoHOLXHologic, Inc.LQDA logoLQDALiquidia Corporat…BDX logoBDXBecton, Dickinson…
ROE (TTM)Return on equity+16.2%-47.6%+11.0%-5.5%+4.5%
ROA (TTM)Return on assets+10.3%-13.7%+6.1%-44.2%+2.1%
ROICReturn on invested capital-5.1%+1.7%+9.4%-5.0%+4.3%
ROCEReturn on capital employed-6.2%+2.2%+8.8%-84.1%+5.4%
Piotroski ScoreFundamental quality 0–945717
Debt / EquityFinancial leverage0.46x1.95x0.52x1.58x0.76x
Net DebtTotal debt minus cash-$20M$1.8B$667M-$54M$18.3B
Cash & Equiv.Liquid assets$250M$235M$2.0B$176M$851M
Total DebtShort + long-term debt$231M$2.0B$2.6B$122M$19.2B
Interest CoverageEBIT ÷ Interest expense-16.64x-10.36x8.00x-4.63x4.09x
HOLX leads this category, winning 4 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

LQDA leads this category, winning 5 of 6 comparable metrics.

A $10,000 investment in LQDA five years ago would be worth $159,547 today (with dividends reinvested), compared to $1,827 for IART. Over the past 12 months, LQDA leads with a +172.2% total return vs IART's +6.5%. The 3-year compound annual growth rate (CAGR) favors LQDA at 77.2% vs IART's -35.4% — a key indicator of consistent wealth creation.

MetricCYRX logoCYRXCryoport, Inc.IART logoIARTIntegra LifeScien…HOLX logoHOLXHologic, Inc.LQDA logoLQDALiquidia Corporat…BDX logoBDXBecton, Dickinson…
YTD ReturnYear-to-date+33.5%+12.9%+1.9%+34.6%+0.7%
1-Year ReturnPast 12 months+125.4%+6.5%+37.1%+172.2%+51.8%
3-Year ReturnCumulative with dividends-42.5%-73.1%-8.5%+456.3%+5.0%
5-Year ReturnCumulative with dividends-79.8%-81.7%+15.8%+1495.5%+16.9%
10-Year ReturnCumulative with dividends+557.7%-63.0%+124.3%+280.9%+80.2%
CAGR (3Y)Annualised 3-year return-16.9%-35.4%-2.9%+77.2%+1.6%
LQDA leads this category, winning 5 of 6 comparable metrics.

Risk & Volatility

HOLX leads this category, winning 2 of 2 comparable metrics.

HOLX is the less volatile stock with a 0.41 beta — it tends to amplify market swings less than IART's 2.34 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. HOLX currently trades 100.0% from its 52-week high vs BDX's 74.6% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricCYRX logoCYRXCryoport, Inc.IART logoIARTIntegra LifeScien…HOLX logoHOLXHologic, Inc.LQDA logoLQDALiquidia Corporat…BDX logoBDXBecton, Dickinson…
Beta (5Y)Sensitivity to S&P 5001.81x2.39x0.45x1.17x0.62x
52-Week HighHighest price in past year$13.28$16.49$76.04$46.67$205.52
52-Week LowLowest price in past year$5.31$8.70$52.81$11.85$100.31
% of 52W HighCurrent price vs 52-week peak+96.1%+82.2%+100.0%+90.6%+74.6%
RSI (14)Momentum oscillator 0–10077.275.969.165.232.2
Avg Volume (50D)Average daily shares traded468K858K10.0M1.1M2.5M
HOLX leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Evenly matched — CYRX and BDX each lead in 1 of 1 comparable metric.

Analyst consensus: CYRX as "Buy", IART as "Buy", HOLX as "Hold", LQDA as "Buy", BDX as "Hold". Consensus price targets imply 30.1% upside for LQDA (target: $55) vs -11.5% for IART (target: $12). BDX is the only dividend payer here at 2.72% yield — a key consideration for income-focused portfolios.

MetricCYRX logoCYRXCryoport, Inc.IART logoIARTIntegra LifeScien…HOLX logoHOLXHologic, Inc.LQDA logoLQDALiquidia Corporat…BDX logoBDXBecton, Dickinson…
Analyst RatingConsensus buy/hold/sellBuyBuyHoldBuyHold
Price TargetConsensus 12-month target$14.67$12.00$79.00$55.00$172.85
# AnalystsCovering analysts182642734
Dividend YieldAnnual dividend ÷ price+2.7%
Dividend StreakConsecutive years of raises101
Dividend / ShareAnnual DPS$4.17
Buyback YieldShare repurchases ÷ mkt cap+1.6%+0.0%+4.4%0.0%+1.8%
Evenly matched — CYRX and BDX each lead in 1 of 1 comparable metric.
Key Takeaway

LQDA leads in 2 of 6 categories (Income & Cash Flow, Total Returns). HOLX leads in 2 (Profitability & Efficiency, Risk & Volatility). 1 tied.

Best OverallHologic, Inc. (HOLX)Leads 2 of 6 categories
Loading custom metrics...

CYRX vs IART vs HOLX vs LQDA vs BDX: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is CYRX or IART or HOLX or LQDA or BDX a better buy right now?

For growth investors, Becton, Dickinson and Company (BDX) is the stronger pick with 8.

2% revenue growth year-over-year, versus -24. 5% for Cryoport, Inc. (CYRX). Cryoport, Inc. (CYRX) offers the better valuation at 9. 1x trailing P/E, making it the more compelling value choice. Analysts rate Cryoport, Inc. (CYRX) a "Buy" — based on 18 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — CYRX or IART or HOLX or LQDA or BDX?

On trailing P/E, Cryoport, Inc.

(CYRX) is the cheapest at 9. 1x versus Hologic, Inc. at 30. 5x. On forward P/E, Integra LifeSciences Holdings Corporation is actually cheaper at 5. 8x — notably different from the trailing picture, reflecting expected earnings growth.

03

Which is the better long-term investment — CYRX or IART or HOLX or LQDA or BDX?

Over the past 5 years, Liquidia Corporation (LQDA) delivered a total return of +1495%, compared to -81.

7% for Integra LifeSciences Holdings Corporation (IART). Over 10 years, the gap is even starker: CYRX returned +601. 0% versus IART's -62. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — CYRX or IART or HOLX or LQDA or BDX?

By beta (market sensitivity over 5 years), Hologic, Inc.

(HOLX) is the lower-risk stock at 0. 45β versus Integra LifeSciences Holdings Corporation's 2. 39β — meaning IART is approximately 427% more volatile than HOLX relative to the S&P 500. On balance sheet safety, Cryoport, Inc. (CYRX) carries a lower debt/equity ratio of 46% versus 195% for Integra LifeSciences Holdings Corporation — giving it more financial flexibility in a downturn.

05

Which is growing faster — CYRX or IART or HOLX or LQDA or BDX?

By revenue growth (latest reported year), Becton, Dickinson and Company (BDX) is pulling ahead at 8.

2% versus -24. 5% for Cryoport, Inc. (CYRX). On earnings-per-share growth, the picture is similar: Cryoport, Inc. grew EPS 163. 3% year-over-year, compared to -73. 6% for Integra LifeSciences Holdings Corporation. Over a 3-year CAGR, BDX leads at 5. 0% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — CYRX or IART or HOLX or LQDA or BDX?

Cryoport, Inc.

(CYRX) is the more profitable company, earning 39. 9% net margin versus -931. 7% for Liquidia Corporation — meaning it keeps 39. 9% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: HOLX leads at 17. 4% versus -866. 6% for LQDA. At the gross margin level — before operating expenses — HOLX leads at 61. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is CYRX or IART or HOLX or LQDA or BDX more undervalued right now?

On forward earnings alone, Integra LifeSciences Holdings Corporation (IART) trades at 5.

8x forward P/E versus 17. 6x for Liquidia Corporation — 11. 8x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for LQDA: 30. 1% to $55. 00.

08

Which pays a better dividend — CYRX or IART or HOLX or LQDA or BDX?

In this comparison, BDX (2.

7% yield) pays a dividend. CYRX, IART, HOLX, LQDA do not pay a meaningful dividend and should not be held primarily for income.

09

Is CYRX or IART or HOLX or LQDA or BDX better for a retirement portfolio?

For long-horizon retirement investors, Becton, Dickinson and Company (BDX) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

62), 2. 7% yield). Integra LifeSciences Holdings Corporation (IART) carries a higher beta of 2. 39 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (BDX: +76. 4%, IART: -62. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between CYRX and IART and HOLX and LQDA and BDX?

These companies operate in different sectors (CYRX (Industrials) and IART (Healthcare) and HOLX (Healthcare) and LQDA (Healthcare) and BDX (Healthcare)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.

In terms of investment character: CYRX is a small-cap deep-value stock; IART is a small-cap quality compounder stock; HOLX is a mid-cap quality compounder stock; LQDA is a small-cap quality compounder stock; BDX is a mid-cap quality compounder stock. BDX pays a dividend while CYRX, IART, HOLX, LQDA do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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  • Market Cap > $100B
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  • Market Cap > $100B
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  • Revenue Growth > 560%
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BDX

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(CYRX: 16.5% · IART: 2.4%)

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