Integrated Freight & Logistics
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5 / 10Stock Comparison
CYRX vs IART vs HOLX vs LQDA vs BDX
Revenue, margins, valuation, and 5-year total return — side by side.
Medical - Devices
Medical - Instruments & Supplies
Biotechnology
Medical - Instruments & Supplies
CYRX vs IART vs HOLX vs LQDA vs BDX — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Integrated Freight & Logistics | Medical - Devices | Medical - Instruments & Supplies | Biotechnology | Medical - Instruments & Supplies |
| Market Cap | $641M | $1.06B | $16.97B | $3.67B | $55.53B |
| Revenue (TTM) | $183M | $1.64B | $4.13B | $69M | $21.36B |
| Net Income (TTM) | $77M | $-496M | $544M | $-122M | $1.14B |
| Gross Margin | 47.2% | 39.6% | 52.8% | 89.4% | 46.5% |
| Operating Margin | -20.2% | 5.8% | 17.5% | -155.0% | 10.6% |
| Forward P/E | 9.1x | 5.8x | 17.2x | 17.6x | 11.9x |
| Total Debt | $231M | $2.03B | $2.63B | $122M | $19.18B |
| Cash & Equiv. | $250M | $235M | $1.96B | $176M | $851M |
CYRX vs IART vs HOLX vs LQDA vs BDX — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Cryoport, Inc. (CYRX) | 100 | 55.4 | -44.6% |
| Integra LifeScience… (IART) | 100 | 26.7 | -73.3% |
| Hologic, Inc. (HOLX) | 100 | 142.6 | +42.6% |
| Liquidia Corporation (LQDA) | 100 | 458.7 | +358.7% |
| Becton, Dickinson a… (BDX) | 100 | 100.4 | +0.4% |
Price return only. Dividends and distributions are not included.
Quick Verdict: CYRX vs IART vs HOLX vs LQDA vs BDX
Each card shows where this stock fits in a portfolio — not just who wins on paper.
CYRX has the current edge in this matchup, primarily because of its strength in quality and efficiency.
- 42.2% margin vs LQDA's -176.0%
- 10.3% ROA vs LQDA's -44.2%, ROIC -5.1% vs -5.0%
IART ranks third and is worth considering specifically for value.
- Lower P/E (5.8x vs 11.9x)
HOLX is the clearest fit if your priority is sleep-well-at-night and defensive.
- Lower volatility, beta 0.41, Low D/E 52.0%, current ratio 3.75x
- Beta 0.41, current ratio 3.75x
- Beta 0.41 vs IART's 2.34, lower leverage
LQDA is the clearest fit if your priority is long-term compounding.
- 280.9% 10Y total return vs CYRX's 5.6%
- +172.2% vs IART's +6.5%
BDX is the #2 pick in this set and the best alternative if income & stability and growth exposure is your priority.
- Dividend streak 1 yrs, beta 0.66, yield 2.7%
- Rev growth 8.2%, EPS growth -0.5%, 3Y rev CAGR 5.0%
- 8.2% revenue growth vs CYRX's -24.5%
- 2.7% yield; 1-year raise streak; the other 4 pay no meaningful dividend
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 8.2% revenue growth vs CYRX's -24.5% | |
| Value | Lower P/E (5.8x vs 11.9x) | |
| Quality / Margins | 42.2% margin vs LQDA's -176.0% | |
| Stability / Safety | Beta 0.41 vs IART's 2.34, lower leverage | |
| Dividends | 2.7% yield; 1-year raise streak; the other 4 pay no meaningful dividend | |
| Momentum (1Y) | +172.2% vs IART's +6.5% | |
| Efficiency (ROA) | 10.3% ROA vs LQDA's -44.2%, ROIC -5.1% vs -5.0% |
CYRX vs IART vs HOLX vs LQDA vs BDX — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
CYRX vs IART vs HOLX vs LQDA vs BDX — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
LQDA leads in 2 of 6 categories
HOLX leads 2 • IART leads 1 • CYRX leads 0 • BDX leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
LQDA leads this category, winning 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
BDX is the larger business by revenue, generating $21.4B annually — 308.7x LQDA's $69M. CYRX is the more profitable business, keeping 42.2% of every revenue dollar as net income compared to LQDA's -176.0%. On growth, LQDA holds the edge at +11.2% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $183M | $1.6B | $4.1B | $69M | $21.4B |
| EBITDAEarnings before interest/tax | -$10M | $209M | $974M | -$106M | $4.2B |
| Net IncomeAfter-tax profit | $77M | -$496M | $544M | -$122M | $1.1B |
| Free Cash FlowCash after capex | -$18M | -$10M | $1000M | -$108M | $3.1B |
| Gross MarginGross profit ÷ Revenue | +47.2% | +39.6% | +52.8% | +89.4% | +46.5% |
| Operating MarginEBIT ÷ Revenue | -20.2% | +5.8% | +17.5% | -155.0% | +10.6% |
| Net MarginNet income ÷ Revenue | +42.2% | -30.1% | +13.2% | -176.0% | +5.3% |
| FCF MarginFCF ÷ Revenue | -9.7% | -0.6% | +24.2% | -155.8% | +14.7% |
| Rev. Growth (YoY)Latest quarter vs prior year | +16.5% | +2.4% | +2.5% | +11.2% | -10.6% |
| EPS Growth (YoY)Latest quarter vs prior year | +10.7% | +81.8% | -9.2% | +86.4% | -2.0% |
Valuation Metrics
IART leads this category, winning 4 of 6 comparable metrics.
Valuation Metrics
At 9.1x trailing earnings, CYRX trades at a 70% valuation discount to HOLX's 30.5x P/E. On an enterprise value basis, IART's 13.0x EV/EBITDA is more attractive than HOLX's 17.4x.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $641M | $1.1B | $17.0B | $3.7B | $55.5B |
| Enterprise ValueMkt cap + debt − cash | $621M | $2.9B | $17.6B | $3.6B | $73.9B |
| Trailing P/EPrice ÷ TTM EPS | 9.11x | -2.01x | 30.53x | -25.47x | 26.29x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 5.77x | 17.21x | 17.58x | 11.90x |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — | 1.59x |
| EV / EBITDAEnterprise value multiple | — | 13.01x | 17.39x | — | 14.65x |
| Price / SalesMarket cap ÷ Revenue | 3.64x | 0.65x | 4.14x | 262.27x | 2.54x |
| Price / BookPrice ÷ Book value/share | 1.27x | 1.00x | 3.43x | 43.06x | 1.73x |
| Price / FCFMarket cap ÷ FCF | — | — | 18.44x | — | 20.80x |
Profitability & Efficiency
HOLX leads this category, winning 4 of 9 comparable metrics.
Profitability & Efficiency
CYRX delivers a 16.2% return on equity — every $100 of shareholder capital generates $16 in annual profit, vs $-6 for LQDA. CYRX carries lower financial leverage with a 0.46x debt-to-equity ratio, signaling a more conservative balance sheet compared to IART's 1.95x. On the Piotroski fundamental quality scale (0–9), HOLX scores 7/9 vs LQDA's 1/9, reflecting strong financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | +16.2% | -47.6% | +11.0% | -5.5% | +4.5% |
| ROA (TTM)Return on assets | +10.3% | -13.7% | +6.1% | -44.2% | +2.1% |
| ROICReturn on invested capital | -5.1% | +1.7% | +9.4% | -5.0% | +4.3% |
| ROCEReturn on capital employed | -6.2% | +2.2% | +8.8% | -84.1% | +5.4% |
| Piotroski ScoreFundamental quality 0–9 | 4 | 5 | 7 | 1 | 7 |
| Debt / EquityFinancial leverage | 0.46x | 1.95x | 0.52x | 1.58x | 0.76x |
| Net DebtTotal debt minus cash | -$20M | $1.8B | $667M | -$54M | $18.3B |
| Cash & Equiv.Liquid assets | $250M | $235M | $2.0B | $176M | $851M |
| Total DebtShort + long-term debt | $231M | $2.0B | $2.6B | $122M | $19.2B |
| Interest CoverageEBIT ÷ Interest expense | -16.64x | -10.36x | 8.00x | -4.63x | 4.09x |
Total Returns (Dividends Reinvested)
LQDA leads this category, winning 5 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in LQDA five years ago would be worth $159,547 today (with dividends reinvested), compared to $1,827 for IART. Over the past 12 months, LQDA leads with a +172.2% total return vs IART's +6.5%. The 3-year compound annual growth rate (CAGR) favors LQDA at 77.2% vs IART's -35.4% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | +33.5% | +12.9% | +1.9% | +34.6% | +0.7% |
| 1-Year ReturnPast 12 months | +125.4% | +6.5% | +37.1% | +172.2% | +51.8% |
| 3-Year ReturnCumulative with dividends | -42.5% | -73.1% | -8.5% | +456.3% | +5.0% |
| 5-Year ReturnCumulative with dividends | -79.8% | -81.7% | +15.8% | +1495.5% | +16.9% |
| 10-Year ReturnCumulative with dividends | +557.7% | -63.0% | +124.3% | +280.9% | +80.2% |
| CAGR (3Y)Annualised 3-year return | -16.9% | -35.4% | -2.9% | +77.2% | +1.6% |
Risk & Volatility
HOLX leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
HOLX is the less volatile stock with a 0.41 beta — it tends to amplify market swings less than IART's 2.34 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. HOLX currently trades 100.0% from its 52-week high vs BDX's 74.6% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.81x | 2.39x | 0.45x | 1.17x | 0.62x |
| 52-Week HighHighest price in past year | $13.28 | $16.49 | $76.04 | $46.67 | $205.52 |
| 52-Week LowLowest price in past year | $5.31 | $8.70 | $52.81 | $11.85 | $100.31 |
| % of 52W HighCurrent price vs 52-week peak | +96.1% | +82.2% | +100.0% | +90.6% | +74.6% |
| RSI (14)Momentum oscillator 0–100 | 77.2 | 75.9 | 69.1 | 65.2 | 32.2 |
| Avg Volume (50D)Average daily shares traded | 468K | 858K | 10.0M | 1.1M | 2.5M |
Analyst Outlook
Evenly matched — CYRX and BDX each lead in 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: CYRX as "Buy", IART as "Buy", HOLX as "Hold", LQDA as "Buy", BDX as "Hold". Consensus price targets imply 30.1% upside for LQDA (target: $55) vs -11.5% for IART (target: $12). BDX is the only dividend payer here at 2.72% yield — a key consideration for income-focused portfolios.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Hold | Buy | Hold |
| Price TargetConsensus 12-month target | $14.67 | $12.00 | $79.00 | $55.00 | $172.85 |
| # AnalystsCovering analysts | 18 | 26 | 42 | 7 | 34 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — | +2.7% |
| Dividend StreakConsecutive years of raises | 1 | 0 | — | — | 1 |
| Dividend / ShareAnnual DPS | — | — | — | — | $4.17 |
| Buyback YieldShare repurchases ÷ mkt cap | +1.6% | +0.0% | +4.4% | 0.0% | +1.8% |
LQDA leads in 2 of 6 categories (Income & Cash Flow, Total Returns). HOLX leads in 2 (Profitability & Efficiency, Risk & Volatility). 1 tied.
CYRX vs IART vs HOLX vs LQDA vs BDX: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is CYRX or IART or HOLX or LQDA or BDX a better buy right now?
For growth investors, Becton, Dickinson and Company (BDX) is the stronger pick with 8.
2% revenue growth year-over-year, versus -24. 5% for Cryoport, Inc. (CYRX). Cryoport, Inc. (CYRX) offers the better valuation at 9. 1x trailing P/E, making it the more compelling value choice. Analysts rate Cryoport, Inc. (CYRX) a "Buy" — based on 18 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — CYRX or IART or HOLX or LQDA or BDX?
On trailing P/E, Cryoport, Inc.
(CYRX) is the cheapest at 9. 1x versus Hologic, Inc. at 30. 5x. On forward P/E, Integra LifeSciences Holdings Corporation is actually cheaper at 5. 8x — notably different from the trailing picture, reflecting expected earnings growth.
03Which is the better long-term investment — CYRX or IART or HOLX or LQDA or BDX?
Over the past 5 years, Liquidia Corporation (LQDA) delivered a total return of +1495%, compared to -81.
7% for Integra LifeSciences Holdings Corporation (IART). Over 10 years, the gap is even starker: CYRX returned +601. 0% versus IART's -62. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — CYRX or IART or HOLX or LQDA or BDX?
By beta (market sensitivity over 5 years), Hologic, Inc.
(HOLX) is the lower-risk stock at 0. 45β versus Integra LifeSciences Holdings Corporation's 2. 39β — meaning IART is approximately 427% more volatile than HOLX relative to the S&P 500. On balance sheet safety, Cryoport, Inc. (CYRX) carries a lower debt/equity ratio of 46% versus 195% for Integra LifeSciences Holdings Corporation — giving it more financial flexibility in a downturn.
05Which is growing faster — CYRX or IART or HOLX or LQDA or BDX?
By revenue growth (latest reported year), Becton, Dickinson and Company (BDX) is pulling ahead at 8.
2% versus -24. 5% for Cryoport, Inc. (CYRX). On earnings-per-share growth, the picture is similar: Cryoport, Inc. grew EPS 163. 3% year-over-year, compared to -73. 6% for Integra LifeSciences Holdings Corporation. Over a 3-year CAGR, BDX leads at 5. 0% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — CYRX or IART or HOLX or LQDA or BDX?
Cryoport, Inc.
(CYRX) is the more profitable company, earning 39. 9% net margin versus -931. 7% for Liquidia Corporation — meaning it keeps 39. 9% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: HOLX leads at 17. 4% versus -866. 6% for LQDA. At the gross margin level — before operating expenses — HOLX leads at 61. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is CYRX or IART or HOLX or LQDA or BDX more undervalued right now?
On forward earnings alone, Integra LifeSciences Holdings Corporation (IART) trades at 5.
8x forward P/E versus 17. 6x for Liquidia Corporation — 11. 8x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for LQDA: 30. 1% to $55. 00.
08Which pays a better dividend — CYRX or IART or HOLX or LQDA or BDX?
In this comparison, BDX (2.
7% yield) pays a dividend. CYRX, IART, HOLX, LQDA do not pay a meaningful dividend and should not be held primarily for income.
09Is CYRX or IART or HOLX or LQDA or BDX better for a retirement portfolio?
For long-horizon retirement investors, Becton, Dickinson and Company (BDX) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.
62), 2. 7% yield). Integra LifeSciences Holdings Corporation (IART) carries a higher beta of 2. 39 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (BDX: +76. 4%, IART: -62. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between CYRX and IART and HOLX and LQDA and BDX?
These companies operate in different sectors (CYRX (Industrials) and IART (Healthcare) and HOLX (Healthcare) and LQDA (Healthcare) and BDX (Healthcare)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.
In terms of investment character: CYRX is a small-cap deep-value stock; IART is a small-cap quality compounder stock; HOLX is a mid-cap quality compounder stock; LQDA is a small-cap quality compounder stock; BDX is a mid-cap quality compounder stock. BDX pays a dividend while CYRX, IART, HOLX, LQDA do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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