Biotechnology
Compare Stocks
2 / 10Stock Comparison
DYAI vs SEER
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
DYAI vs SEER — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||
|---|---|---|
| Industry | Biotechnology | Biotechnology |
| Market Cap | $27M | $105M |
| Revenue (TTM) | $3M | $16M |
| Net Income (TTM) | $-7M | $-79M |
| Gross Margin | 42.2% | 40.7% |
| Operating Margin | -273.4% | -5.2% |
| Total Debt | $5M | $26M |
| Cash & Equiv. | $7M | $41M |
DYAI vs SEER — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Dec 20 | May 26 | Return |
|---|---|---|---|
| Dyadic Internationa… (DYAI) | 100 | 13.8 | -86.2% |
| Seer, Inc. (SEER) | 100 | 3.3 | -96.7% |
Price return only. Dividends and distributions are not included.
Quick Verdict: DYAI vs SEER
Each card shows where this stock fits in a portfolio — not just who wins on paper.
DYAI is the clearest fit if your priority is growth exposure and long-term compounding.
- Rev growth 20.6%, EPS growth 16.7%, 3Y rev CAGR 13.3%
- -56.4% 10Y total return vs SEER's -96.7%
- 20.6% revenue growth vs SEER's -8.1%
SEER carries the broadest edge in this set and is the clearest fit for income & stability and sleep-well-at-night.
- beta 0.84
- Lower volatility, beta 0.84, Low D/E 7.9%, current ratio 16.53x
- Beta 0.84, current ratio 16.53x
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 20.6% revenue growth vs SEER's -8.1% | |
| Quality / Margins | -279.6% margin vs SEER's -486.0% | |
| Stability / Safety | Beta 0.84 vs DYAI's 0.98, lower leverage | |
| Dividends | Tie | Neither stock pays a meaningful dividend |
| Momentum (1Y) | +1.6% vs DYAI's -31.7% | |
| Efficiency (ROA) | -25.7% ROA vs DYAI's -63.0%, ROIC -21.3% vs -16.7% |
DYAI vs SEER — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
DYAI vs SEER — Financial Metrics
Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.
Income & Cash Flow (Last 12 Months)
DYAI leads this category, winning 4 of 5 comparable metrics.
Income & Cash Flow (Last 12 Months)
SEER is the larger business by revenue, generating $16M annually — 6.2x DYAI's $3M. Profitability is closely matched — net margins range from -2.8% (DYAI) to -4.9% (SEER). On growth, SEER holds the edge at +4.5% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||
|---|---|---|
| RevenueTrailing 12 months | $3M | $16M |
| EBITDAEarnings before interest/tax | -$7M | -$76M |
| Net IncomeAfter-tax profit | -$7M | -$79M |
| Free Cash FlowCash after capex | -$5M | -$46M |
| Gross MarginGross profit ÷ Revenue | +42.2% | +40.7% |
| Operating MarginEBIT ÷ Revenue | -2.7% | -5.2% |
| Net MarginNet income ÷ Revenue | -2.8% | -4.9% |
| FCF MarginFCF ÷ Revenue | -176.1% | -2.8% |
| Rev. Growth (YoY)Latest quarter vs prior year | -40.5% | +4.5% |
| EPS Growth (YoY)Latest quarter vs prior year | — | +8.6% |
Valuation Metrics
SEER leads this category, winning 2 of 3 comparable metrics.
Valuation Metrics
| Metric | ||
|---|---|---|
| Market CapShares × price | $27M | $105M |
| Enterprise ValueMkt cap + debt − cash | $26M | $90M |
| Trailing P/EPrice ÷ TTM EPS | -3.73x | -1.35x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — |
| EV / EBITDAEnterprise value multiple | — | — |
| Price / SalesMarket cap ÷ Revenue | 7.71x | 7.52x |
| Price / BookPrice ÷ Book value/share | 8.84x | 0.36x |
| Price / FCFMarket cap ÷ FCF | — | — |
Profitability & Efficiency
SEER leads this category, winning 7 of 8 comparable metrics.
Profitability & Efficiency
SEER delivers a -29.2% return on equity — every $100 of shareholder capital generates $-29 in annual profit, vs $-3 for DYAI. SEER carries lower financial leverage with a 0.08x debt-to-equity ratio, signaling a more conservative balance sheet compared to DYAI's 2.05x. On the Piotroski fundamental quality scale (0–9), SEER scores 4/9 vs DYAI's 3/9, reflecting mixed financial health.
| Metric | ||
|---|---|---|
| ROE (TTM)Return on equity | -2.8% | -29.2% |
| ROA (TTM)Return on assets | -63.0% | -25.7% |
| ROICReturn on invested capital | -16.7% | -21.3% |
| ROCEReturn on capital employed | -87.7% | -25.9% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 4 |
| Debt / EquityFinancial leverage | 2.05x | 0.08x |
| Net DebtTotal debt minus cash | -$1M | -$15M |
| Cash & Equiv.Liquid assets | $7M | $41M |
| Total DebtShort + long-term debt | $5M | $26M |
| Interest CoverageEBIT ÷ Interest expense | -15.72x | — |
Total Returns (Dividends Reinvested)
SEER leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in DYAI five years ago would be worth $1,791 today (with dividends reinvested), compared to $494 for SEER. Over the past 12 months, SEER leads with a +1.6% total return vs DYAI's -31.7%. The 3-year compound annual growth rate (CAGR) favors SEER at -19.2% vs DYAI's -24.7% — a key indicator of consistent wealth creation.
| Metric | ||
|---|---|---|
| YTD ReturnYear-to-date | -20.7% | +3.3% |
| 1-Year ReturnPast 12 months | -31.7% | +1.6% |
| 3-Year ReturnCumulative with dividends | -57.4% | -47.2% |
| 5-Year ReturnCumulative with dividends | -82.1% | -95.1% |
| 10-Year ReturnCumulative with dividends | -56.4% | -96.7% |
| CAGR (3Y)Annualised 3-year return | -24.7% | -19.2% |
Risk & Volatility
SEER leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
SEER is the less volatile stock with a 0.84 beta — it tends to amplify market swings less than DYAI's 0.98 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. SEER currently trades 78.0% from its 52-week high vs DYAI's 55.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.98x | 0.84x |
| 52-Week HighHighest price in past year | $1.35 | $2.41 |
| 52-Week LowLowest price in past year | $0.66 | $1.65 |
| % of 52W HighCurrent price vs 52-week peak | +55.2% | +78.0% |
| RSI (14)Momentum oscillator 0–100 | 41.4 | 49.8 |
| Avg Volume (50D)Average daily shares traded | 75K | 401K |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
| Metric | ||
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Hold |
| Price TargetConsensus 12-month target | — | — |
| # AnalystsCovering analysts | — | 4 |
| Dividend YieldAnnual dividend ÷ price | — | — |
| Dividend StreakConsecutive years of raises | — | — |
| Dividend / ShareAnnual DPS | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +11.3% |
SEER leads in 4 of 6 categories (Valuation Metrics, Profitability & Efficiency). DYAI leads in 1 (Income & Cash Flow).
DYAI vs SEER: Frequently Asked Questions
8 questions · data-driven answers · updated daily
01Is DYAI or SEER a better buy right now?
For growth investors, Dyadic International, Inc.
(DYAI) is the stronger pick with 20. 6% revenue growth year-over-year, versus -8. 1% for Seer, Inc. (SEER). Analysts rate Seer, Inc. (SEER) a "Hold" — based on 4 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — DYAI or SEER?
Over the past 5 years, Dyadic International, Inc.
(DYAI) delivered a total return of -82. 1%, compared to -95. 1% for Seer, Inc. (SEER). Over 10 years, the gap is even starker: DYAI returned -56. 4% versus SEER's -96. 7%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — DYAI or SEER?
By beta (market sensitivity over 5 years), Seer, Inc.
(SEER) is the lower-risk stock at 0. 84β versus Dyadic International, Inc. 's 0. 98β — meaning DYAI is approximately 17% more volatile than SEER relative to the S&P 500. On balance sheet safety, Seer, Inc. (SEER) carries a lower debt/equity ratio of 8% versus 2% for Dyadic International, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — DYAI or SEER?
By revenue growth (latest reported year), Dyadic International, Inc.
(DYAI) is pulling ahead at 20. 6% versus -8. 1% for Seer, Inc. (SEER). On earnings-per-share growth, the picture is similar: Dyadic International, Inc. grew EPS 16. 7% year-over-year, compared to -3. 0% for Seer, Inc.. Over a 3-year CAGR, SEER leads at 29. 7% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — DYAI or SEER?
Dyadic International, Inc.
(DYAI) is the more profitable company, earning -166. 2% net margin versus -620. 9% for Seer, Inc. — meaning it keeps -166. 2% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: DYAI leads at -168. 8% versus -717. 7% for SEER. At the gross margin level — before operating expenses — DYAI leads at 65. 8%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — DYAI or SEER?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is DYAI or SEER better for a retirement portfolio?
For long-horizon retirement investors, Seer, Inc.
(SEER) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 84)). Both have compounded well over 10 years (SEER: -96. 7%, DYAI: -56. 4%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between DYAI and SEER?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: DYAI is a small-cap high-growth stock; SEER is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
Find Stocks Like These
Explore pre-built screens for each stock's profile, or build a custom screen to find stocks that outperform both.
You Might Also Compare
Based on how these companies actually compete and overlap — not just which sector they're filed under.