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DYAI logoDyadic International, Inc.(DYAI)Earnings, Financials & Key Ratios

DYAI•NASDAQ
$0.76
$28M mkt cap·Price updated May 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryDrug Discovery and Antibody Platforms
AboutDyadic International, Inc., a biotechnology platform company, develops, produces, and sells enzymes and other proteins in the United States. The company utilizes its patented and proprietary C1 platform and other technologies to conduct research, development, and commercial activities for the development and manufacturing of human and animal vaccines and drugs, such as virus like particles and antigens, monoclonal antibodies, bi/tri-specific antibodies, fab antibody fragments, Fc-fusion proteins, biosimilars and/or biobetters, and other therapeutic enzymes and proteins. It offers DYAI-100, SARS-CoV-2-RBD antigen vaccine candidate towards a first-in-human Phase 1 clinical trial, is to validate to serve as proof of concept for the development of next generation multivariant COVID-19 vaccine candidates. The company has a research and development agreement with VTT Technical Research Centre of Finland, Ltd.; strategic research services agreement with Biotechnology Developments for Industry in Pharmaceuticals, S.L.U.; and collaboration with Syngene International Limited. Dyadic International, Inc. was founded in 1979 and is headquartered in Jupiter, Florida.Show more
  • Revenue$3M+20.6%
  • EBITDA-$5M+34.3%
  • Net Income-$6M+14.5%
  • EPS (Diluted)-0.20+16.7%
  • Gross Margin65.82%+106.7%
  • EBITDA Margin-153.95%+45.5%
  • Operating Margin-168.82%+40.5%
  • Net Margin-166.19%+29.1%
  • ROE-139.16%-73.7%
  • ROIC-1669.28%-548.3%
  • Debt/Equity2.05+8704.6%
  • Interest Coverage-13.79
Technical→

DYAI Key Insights

Dyadic International, Inc. (DYAI) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Strong 5Y sales CAGR of 15.8%

✗Weaknesses

  • ✗High debt to equity ratio of 2.1x
  • ✗Weak Piotroski F-Score: 3/9
  • ✗Negative free cash flow
  • ✗Trading more than 30% below 52-week high

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

DYAI Price & Volume

Dyadic International, Inc. (DYAI) stock price & volume — 10-year historical chart

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DYAI Growth Metrics

Dyadic International, Inc. (DYAI) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-11.98%
5 Years15.77%
3 Years13.29%
TTM-21.88%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-16.08%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-10.08%

Return on Capital

10 Years-41.62%
5 Years-68.92%
3 Years-83.67%
Last Year-87.75%

DYAI Peer Comparison

Dyadic International, Inc. (DYAI) competitors in Drug Discovery and Antibody Platforms — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
CDXS logoCDXSCodexis, Inc.Direct Competitor241.71M2.66-5.3218.61%-62.47%-90.51%1.45
GEVO logoGEVOGevo, Inc.Direct Competitor497.05M2.05-14.648.49%0.75%0.25%0.01
TWST logoTWSTTwist Bioscience CorporationProduct Competitor3.71B59.53-45.7920.32%-19.85%-17.46%0.29
SEER logoSEERSeer, Inc.Product Competitor105.44M1.89-1.36-8.13%-486.02%-29.19%0.08
BEAM logoBEAMBeam Therapeutics Inc.Product Competitor3.32B32.33-39.92120.01%-57.24%-7.31%0.24
BNGO logoBNGOBionano Genomics, Inc.Product Competitor13.64M1.27-0.26-7.37%-92.59%-56.22%0.16
MRK logoMRKMerck & Co., Inc.Supply Chain280.48B113.5615.601.18%28.12%36.14%0.96
PFE logoPFEPfizer Inc.Supply Chain150.77B26.5119.49-1.65%11.83%8.34%0.78

Compare DYAI vs Peers

Dyadic International, Inc. (DYAI) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs CDXS

Most directly comparable listed peer for DYAI.

Scale Benchmark

vs MRK

Larger-name benchmark to compare DYAI against a more recognizable public peer.

Peer Set

Compare Top 5

vs CDXS, GEVO, TWST, SEER

DYAI Income Statement

Dyadic International, Inc. (DYAI) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
Line itemDec'16Dec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24TTM
Sales/Revenue592.89K758.42K1.3M1.68M1.6M2.4M2.93M2.9M3.5M2.63M
Revenue Growth %87.79%27.92%70.81%29.77%-4.71%50.06%21.9%-1.07%20.58%-21.88%
Cost of Goods Sold516.16K680.2K1.03M1.46M1.42M1.94M2.12M1.98M1.19M1.52M
COGS % of Revenue87.06%89.69%79.3%86.83%88.95%80.89%72.46%68.16%34.18%-
Gross Profit
76.72K▲ 0%
78.22K▲ 2.0%
268.17K▲ 242.8%
221.38K▼ 17.5%
176.99K▼ 20.0%
459.39K▲ 159.6%
807.11K▲ 75.7%
922.96K▲ 14.4%
2.3M▲ 149.3%
1.11M▲ 0%
Gross Margin %12.94%10.31%20.7%13.17%11.05%19.11%27.54%31.84%65.82%42.22%
Gross Profit Growth %-59.98%1.95%242.83%-17.45%-20.05%159.56%75.69%14.35%149.28%-
Operating Expenses5.88M7.45M7.84M9.5M10.2M15.19M10.97M9.15M8.2M8.3M
OpEx % of Revenue992.54%982.85%605.18%565.35%636.9%631.78%374.46%315.74%234.64%-
Selling, General & Admin4.56M5.03M4.52M5.52M6.08M6.7M6.42M5.82M6.13M5.95M
SG&A % of Revenue769.48%663.27%349.12%328.36%379.84%278.62%219.14%200.67%175.51%-
Research & Development885.6K2.2M3.32M5.42M3.87M8.39M4.5M3.3M2.04M2.02M
R&D % of Revenue149.37%290.48%256.06%322.18%241.47%349.12%153.61%113.75%58.48%-
Other Operating Expenses436.92K220.72K0-1.43M249.73K96.89K49.92K38.42K22.56K318.03K
Operating Income
-5.96M▲ 0%
-7.13M▼ 19.7%
-7.59M▼ 6.5%
-9.28M▼ 22.3%
-10.03M▼ 8.0%
-14.73M▼ 46.9%
-10.17M▲ 31.0%
-8.23M▲ 19.0%
-5.9M▲ 28.3%
-7.19M▲ 0%
Operating Margin %-1004.45%-939.7%-586.09%-552.18%-625.85%-612.67%-346.92%-283.9%-168.82%-273.42%
Operating Income Growth %-63.32%-19.67%-6.53%-22.26%-8%-46.9%30.97%19.04%28.3%-
EBITDA-147.34K249.06K-188.78K-27.73K-9.96M-11.24M-10.12M-8.19M-5.38M-6.91M
EBITDA Margin %-24.85%32.84%-14.57%-1.65%-621.96%-467.48%-345.21%-282.58%-153.95%-262.83%
EBITDA Growth %97.47%269.04%-175.8%85.31%-35836.22%-12.79%9.98%19.02%34.31%-74.61%
D&A (Non-Cash Add-back)5.81M7.38M7.4M9.25M03.49M038.42K00
EBIT-5.81M-7.38M-7.57M-9.25M-9.96M-14.63M-10.12M-8.19M-5.38M-6.91M
Net Interest Income484.58K566.15K894.53K984.93K447K51.7K180.42K416.69K29.02K-134.76K
Interest Income485.49K00984.93K447K51.7K180.42K416.69K456.99K304.8K
Interest Expense909566.15K894.53K00000427.97K439.56K
Other Income/Expense2.58M4.92M894.53K984.93K731.71K1.66M430.42K1.43M91.66K-161.27K
Pretax Income
-3.37M▲ 0%
-2.2M▲ 34.7%
-6.7M▼ 204.1%
-8.3M▼ 23.9%
-9.29M▼ 12.0%
-13.07M▼ 40.6%
-9.74M▲ 25.5%
-6.8M▲ 30.2%
-5.81M▲ 14.5%
-7.35M▲ 0%
Pretax Margin %-568.52%-290.41%-517.03%-493.59%-580.18%-543.73%-332.23%-234.42%-166.19%-279.56%
Income Tax238.07K-66.69K-1.01M10.31K31.32K00000
Effective Tax Rate %-7.06%3.03%15.02%-0.12%-0.34%0%0%0%0%0%
Net Income
-3.61M▲ 0%
-2.14M▲ 40.8%
-5.69M▼ 166.5%
-8.31M▼ 46.0%
-9.33M▼ 12.2%
-13.07M▼ 40.2%
-9.74M▲ 25.5%
-6.8M▲ 30.2%
-5.81M▲ 14.5%
-7.35M▲ 0%
Net Margin %-608.67%-281.61%-439.36%-494.21%-582.13%-543.73%-332.23%-234.42%-166.19%-279.56%
Net Income Growth %-105.49%40.82%-166.49%-45.96%-12.25%-40.16%25.52%30.2%14.51%-16.08%
Net Income (Continuing)-3.61M-2.14M-5.69M-8.31M-9.33M-13.07M-9.74M-6.8M-5.81M-7.35M
Discontinued Operations0000000000
Minority Interest0000000000
EPS (Diluted)
-0.10▲ 0%
-0.07▲ 25.2%
-0.21▼ 184.2%
-0.31▼ 47.6%
-0.34▼ 9.7%
-0.47▼ 38.2%
-0.34▲ 27.7%
-0.24▲ 29.4%
-0.20▲ 16.7%
-0.21▲ 0%
EPS Growth %-105.17%25.2%-184.17%-47.62%-9.68%-38.24%27.66%29.41%16.67%-10.08%
EPS (Basic)-0.10-0.07-0.21-0.31-0.34-0.47-0.34-0.24-0.20-
Diluted Shares Outstanding36.54M28.92M27.67M27M27.47M27.84M28.36M28.8M29.32M34.51M
Basic Shares Outstanding36.54M28.92M27.67M27M27.47M27.84M28.36M28.8M29.32M34.51M
Dividend Payout Ratio----------

DYAI Balance Sheet

Dyadic International, Inc. (DYAI) balance sheet — assets, liabilities & shareholders' equity

Line itemDec'16Dec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24TTM
Total Current Assets57.63M49.62M42.75M35.64M29.78M21.01M13.42M8.07M9.83M11.55M
Cash & Short-Term Investments48.94M47.69M41.2M34.22M29.09M20.26M12.64M7.26M9.26M10.25M
Cash Only6.89M5.79M2.39M4.82M20.64M15.75M5.79M6.52M6.51M7.16M
Short-Term Investments42.05M41.9M38.82M29.4M8.46M4.51M6.85M748.29K2.76M3.1M
Accounts Receivable1.08M760.87K1.12M1.14M294.2K372.21K330K466.16K237.03K950.69K
Days Sales Outstanding665.72366.18315.52247.2167.0356.5241.1158.724.7573.76
Inventory7.36M1.02M253.45K0000000
Days Inventory Outstanding5.21K544.7690.05-------
Other Current Assets0000112.25K058.28K10.08K24.25K339.94K
Total Non-Current Assets1.07M1.13M552.75K1.81M290.93K290.83K290.75K151.9K102.61K127.5K
Property, Plant & Equipment0000000141.44K92.21K52.4K
Fixed Asset Turnover-------20.50x37.91x36.28x
Goodwill0000000000
Intangible Assets0000000000
Long-Term Investments1.07M922.65K500.62K1.76M284.71K284.71K284.71K00474.23K
Other Non-Current Assets5.85K205.74K52.14K51.31K6.22K6.12K6.04K10.46K10.4K287.04K
Total Assets
58.7M▲ 0%
50.74M▼ 13.6%
43.3M▼ 14.7%
37.45M▼ 13.5%
30.07M▼ 19.7%
21.3M▼ 29.2%
13.71M▼ 35.6%
8.22M▼ 40.1%
9.93M▲ 20.8%
11.67M▲ 0%
Asset Turnover0.01x0.01x0.03x0.04x0.05x0.11x0.21x0.35x0.35x0.28x
Asset Growth %-23.43%-13.55%-14.67%-13.51%-19.71%-29.17%-35.62%-40.06%20.82%-32.35%
Total Current Liabilities1.01M768.89K849.64K1.59M1.63M2.56M2.45M2.25M2.45M4.05M
Accounts Payable279.06K520.26K309.06K793K1.01M1.55M1.28M656.45K482.32K705.83K
Days Payables Outstanding197.33279.18109.81198.29259.51290.57219.41121.27147.37142.71
Short-Term Debt00000000048.93K
Deferred Revenue (Current)216.32K0141K78.64K0147.06K0001.34M
Other Current Liabilities515.56K100.67K141K242K123.02K151.15K217.21K490.11K833.81K1.47M
Current Ratio57.04x64.53x50.31x22.44x18.32x8.22x5.48x3.58x4.01x4.01x
Quick Ratio49.75x63.21x50.01x22.44x18.32x8.22x5.48x3.58x4.01x4.01x
Cash Conversion Cycle5.68K631.76295.76-------68.95
Total Non-Current Liabilities495.38K520.26K309.06K00352.94K176.47K88.87K5.01M5.01M
Long-Term Debt000000004.98M5.01M
Capital Lease Obligations000000088.87K34.62K59.67K
Deferred Tax Liabilities0000000000
Other Non-Current Liabilities000000176.47K00-1
Total Liabilities1.01M768.89K849.64K1.59M1.63M2.91M2.63M2.34M7.46M9.07M
Total Debt0000000136.93K5.07M5.06M
Net Debt-6.89M-5.79M-2.39M-4.82M-20.64M-15.75M-5.79M-6.38M-1.44M-2.09M
Debt / Equity-------0.02x2.05x2.05x
Debt / EBITDA----------0.73x
Net Debt / EBITDA--23.23x-------0.30x
Interest Coverage-6551.43x-12.59x-8.49x------13.79x-15.72x
Total Equity
57.69M▲ 0%
49.98M▼ 13.4%
42.45M▼ 15.1%
35.86M▼ 15.5%
28.45M▼ 20.7%
18.39M▼ 35.4%
11.09M▼ 39.7%
5.88M▼ 47.0%
2.47M▼ 58.0%
2.61M▲ 0%
Equity Growth %-21.82%-13.37%-15.06%-15.52%-20.68%-35.35%-39.71%-46.98%-57.98%-277.83%
Book Value per Share1.581.731.531.331.040.660.390.200.080.08
Total Shareholders' Equity57.69M49.98M42.45M35.86M28.45M18.39M11.09M5.88M2.47M2.61M
Common Stock38.93K38.94K38.97K39.61K39.75K40.48K40.82K41.06K42.09K48.44K
Retained Earnings-25.2M-27.35M-33.04M-41.35M-50.68M-63.75M-73.48M-80.28M-86.09M-91.88M
Treasury Stock-10.4M-16.63M-18.93M-18.93M-18.93M-18.93M-18.93M-18.93M-18.93M-18.93M
Accumulated OCI0000000000
Minority Interest0000000000

DYAI Cash Flow Statement

Dyadic International, Inc. (DYAI) cash flow — operating, investing & free cash flow history

Line itemDec'16Dec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24TTM
Cash from Operations-6.04M-2.61M-4.41M-5.78M-6.57M-11.28M-8.08M-6.73M-3.97M-3.97M
Operating CF Margin %-1017.97%-343.64%-340.2%-344%-410.41%-469.12%-275.87%-232.05%-113.72%-
Operating CF Growth %-651.91%56.82%-69.1%-31.21%-13.69%-71.53%28.32%16.79%40.91%-778.53%
Net Income-3.61M-2.14M-5.69M-8.31M-9.33M-13.07M-9.74M-6.8M-5.81M-7.35M
Depreciation & Amortization00676.64K00000010.34K
Stock-Based Compensation624.81K643.43K467.2K001.78M1.89M1.24M0840.3K
Deferred Taxes00-676.64K0000000
Other Non-Cash Items-359.59K-273.09K697.42K1.4M1.76M-1.18M83.71K-1.03M1.08M221.85K
Working Capital Changes-2.69M-840.78K119.94K1.13M990.08K1.19M-321.17K-143.21K754.53K1.65M
Change in Receivables-513.47K333.02K-59.98K218.62K1.08M-13.92K-47.17K-93.13K205.26K-561.97K
Change in Inventory-1.96M-1.21M234.68K0000000
Change in Payables-339.74K207.43K-195.75K657.66K-53.2K549.56K-248.13K-651.17K-180.18K610.79K
Cash from Investing-42.56M103K3.33M7.71M22.12M5.22M-2.37M7.45M-1.88M877.2K
Capital Expenditures000000000-5
CapEx % of Revenue---0%0%---0%-
Acquisitions0000000000
Investments----------
Other Investing-42.56M-812.08K3.33M0000005
Cash from Financing-13.12M-6.22M-2.3M550.19K255.47K1.23M543.59K05.85M4.99M
Debt Issued (Net)000000005.82M-5.82M
Equity Issued (Net)-1000K-1000K-1000K550.19K255.47K00024.25K1.05M
Dividends Paid0000000000
Share Repurchases-13.29M-6.22M-2.3M0000000
Other Financing66.13K1.44K4.5K001.23M543.59K005.82M
Net Change in Cash
-61.71M▲ 0%
-8.47M▲ 86.3%
-3.4M▲ 59.8%
2.44M▲ 171.7%
15.81M▲ 548.8%
-4.89M▼ 130.9%
-9.95M▼ 103.6%
720.76K▲ 107.2%
-8.28K▼ 101.1%
1.48M▲ 0%
Free Cash Flow
-6.04M▲ 0%
-2.61M▲ 56.8%
-4.41M▼ 69.1%
-5.78M▼ 31.2%
-6.57M▼ 13.7%
-11.28M▼ 71.5%
-8.08M▲ 28.3%
-6.73M▲ 16.8%
-3.97M▲ 40.9%
-4.63M▲ 0%
FCF Margin %-1017.97%-343.64%-340.2%-344%-410.41%-469.12%-275.87%-232.05%-113.72%-176.09%
FCF Growth %-651.91%56.82%-69.1%-31.21%-13.69%-71.53%28.32%16.79%40.91%-10.16%
FCF per Share-0.17-0.09-0.16-0.21-0.24-0.41-0.28-0.23-0.14-0.14
FCF Conversion (FCF/Net Income)1.67x1.22x0.77x0.70x0.71x0.86x0.83x0.99x0.68x0.63x
Interest Paid90900000000108K
Taxes Paid11.5K000000000

DYAI Key Ratios

Dyadic International, Inc. (DYAI) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric201620172018201920202021202220232024TTM
Return on Equity (ROE)-5.49%-3.97%-12.32%-21.22%-29%-55.81%-66.05%-80.11%-139.16%-281.83%
Return on Invested Capital (ROIC)-15.95%-11.25%-13.52%-19.58%-38.71%-211.37%-192.16%-257.5%-1669.28%-1669.28%
Gross Margin12.94%10.31%20.7%13.17%11.05%19.11%27.54%31.84%65.82%42.22%
Net Margin-608.67%-281.61%-439.36%-494.21%-582.13%-543.73%-332.23%-234.42%-166.19%-279.56%
Debt / Equity-------0.02x2.05x2.05x
Interest Coverage-6551.43x-12.59x-8.49x------13.79x-15.72x
FCF Conversion1.67x1.22x0.77x0.70x0.71x0.86x0.83x0.99x0.68x0.63x
Revenue Growth87.79%27.92%70.81%29.77%-4.71%50.06%21.9%-1.07%20.58%-21.88%

DYAI Frequently Asked Questions

Dyadic International, Inc. (DYAI) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Dyadic International, Inc. (DYAI) reported $2.6M in revenue for fiscal year 2024. This represents a 1144% increase from $0.2M in 2003.

Dyadic International, Inc. (DYAI) grew revenue by 20.6% over the past year. This is strong growth.

Dyadic International, Inc. (DYAI) reported a net loss of $7.3M for fiscal year 2024.

Dividend & Returns

Dyadic International, Inc. (DYAI) has a return on equity (ROE) of -139.2%. Negative ROE indicates the company is unprofitable.

Dyadic International, Inc. (DYAI) had negative free cash flow of $4.6M in fiscal year 2024, likely due to heavy capital investments.

Explore More DYAI

Dyadic International, Inc. (DYAI) financial analysis — history, returns, DCA and operating performance tools

Total Return Calculator

Historical returns with dividends reinvested

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DCA Calculator

Dollar cost averaging vs lump sum

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Dividend History

Yield, growth, payout safety & DRIP

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Earnings History

EPS trends, net income & profitability

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Price History

Long-term charts & historical price data

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Revenue History

Sales growth patterns & revenue breakdown

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Financial Ratios

30 years of market, efficiency and balance-sheet ratios

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Valuation

DCF intrinsic value, peer multiples & estimates

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