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Stock Comparison

EBS vs JNJ vs PFE vs MRK vs MCK

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
EBS
Emergent BioSolutions Inc.

Drug Manufacturers - Specialty & Generic

HealthcareNYSE • US
Market Cap$472M
5Y Perf.-88.6%
JNJ
Johnson & Johnson

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$536.23B
5Y Perf.+48.8%
PFE
Pfizer Inc.

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$150.63B
5Y Perf.-29.1%
MRK
Merck & Co., Inc.

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$277.34B
5Y Perf.+44.7%
MCK
McKesson Corporation

Medical - Distribution

HealthcareNYSE • US
Market Cap$92.15B
5Y Perf.+364.2%

EBS vs JNJ vs PFE vs MRK vs MCK — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
EBS logoEBS
JNJ logoJNJ
PFE logoPFE
MRK logoMRK
MCK logoMCK
IndustryDrug Manufacturers - Specialty & GenericDrug Manufacturers - GeneralDrug Manufacturers - GeneralDrug Manufacturers - GeneralMedical - Distribution
Market Cap$472M$536.23B$150.63B$277.34B$92.15B
Revenue (TTM)$743M$92.15B$63.31B$64.93B$403.43B
Net Income (TTM)$53M$25.12B$7.49B$18.25B$4.76B
Gross Margin47.1%68.1%69.3%74.2%3.6%
Operating Margin14.7%26.1%23.4%41.1%1.5%
Forward P/E29.2x19.1x8.7x21.7x16.7x
Total Debt$572M$36.63B$67.42B$50.53B$7.39B
Cash & Equiv.$205M$24.11B$1.14B$14.56B$5.69B

EBS vs JNJ vs PFE vs MRK vs MCKLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

EBS
JNJ
PFE
MRK
MCK
StockMay 20May 26Return
Emergent BioSolutio… (EBS)10011.4-88.6%
Johnson & Johnson (JNJ)100148.8+48.8%
Pfizer Inc. (PFE)10070.9-29.1%
Merck & Co., Inc. (MRK)100144.7+44.7%
McKesson Corporation (MCK)100464.2+364.2%

Price return only. Dividends and distributions are not included.

Quick Verdict: EBS vs JNJ vs PFE vs MRK vs MCK

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: PFE and MRK are tied at the top with 2 categories each (5-stock set) — the right choice depends on your priorities. Merck & Co., Inc. is the stronger pick specifically for profitability and margin quality and operational efficiency and capital deployment. MCK and EBS also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
EBS
Emergent BioSolutions Inc.
The Momentum Pick

EBS is the clearest fit if your priority is momentum.

  • +92.7% vs MCK's +4.6%
Best for: momentum
JNJ
Johnson & Johnson
The Income Pick

JNJ is the clearest fit if your priority is income & stability and sleep-well-at-night.

  • Dividend streak 36 yrs, beta 0.06, yield 2.2%
  • Lower volatility, beta 0.06, Low D/E 51.2%, current ratio 1.11x
Best for: income & stability and sleep-well-at-night
PFE
Pfizer Inc.
The Value Play

PFE has the current edge in this matchup, primarily because of its strength in value and dividends.

  • Lower P/E (8.7x vs 21.7x)
  • 6.5% yield, 15-year raise streak, vs JNJ's 2.2%, (1 stock pays no dividend)
Best for: value and dividends
MRK
Merck & Co., Inc.
The Defensive Pick

MRK is the #2 pick in this set and the best alternative if defensive is your priority.

  • Beta 0.48, yield 2.9%, current ratio 1.54x
  • 28.1% margin vs MCK's 1.2%
  • 14.6% ROA vs PFE's 3.6%, ROIC 22.0% vs 7.5%
Best for: defensive
MCK
McKesson Corporation
The Growth Play

MCK ranks third and is worth considering specifically for growth exposure and long-term compounding.

  • Rev growth 16.2%, EPS growth 14.9%, 3Y rev CAGR 10.8%
  • 348.1% 10Y total return vs MRK's 166.5%
  • PEG 0.43 vs JNJ's 34.02
  • 16.2% revenue growth vs EBS's -28.8%
Best for: growth exposure and long-term compounding
See the full category breakdown
CategoryWinnerWhy
GrowthMCK logoMCK16.2% revenue growth vs EBS's -28.8%
ValuePFE logoPFELower P/E (8.7x vs 21.7x)
Quality / MarginsMRK logoMRK28.1% margin vs MCK's 1.2%
Stability / SafetyMCK logoMCKBeta 0.04 vs EBS's 1.83
DividendsPFE logoPFE6.5% yield, 15-year raise streak, vs JNJ's 2.2%, (1 stock pays no dividend)
Momentum (1Y)EBS logoEBS+92.7% vs MCK's +4.6%
Efficiency (ROA)MRK logoMRK14.6% ROA vs PFE's 3.6%, ROIC 22.0% vs 7.5%

EBS vs JNJ vs PFE vs MRK vs MCK — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

EBSEmergent BioSolutions Inc.
FY 2025
Product
94.9%$705M
Contracts and Grants
5.1%$38M
JNJJohnson & Johnson
FY 2024
Innovative Medicine
64.1%$57.0B
MedTech
35.9%$31.9B
PFEPfizer Inc.
FY 2025
Biopharma Segment
97.8%$61.2B
Segment Reporting, Reconciling Item, Corporate Nonsegment
2.2%$1.4B
MRKMerck & Co., Inc.
FY 2025
Pharmaceutical segment
89.4%$58.1B
Animal Health segment
9.8%$6.4B
Other Segments
0.8%$515M
MCKMcKesson Corporation
FY 2025
U.S. Pharmaceutical Segment
91.3%$327.7B
International Segment
4.1%$14.7B
Medical-Surgical Solutions Segment
3.2%$11.4B
Prescription Technology Solutions
1.5%$5.2B

EBS vs JNJ vs PFE vs MRK vs MCK — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLEBSLAGGINGPFE

Income & Cash Flow (Last 12 Months)

MRK leads this category, winning 3 of 6 comparable metrics.

MCK is the larger business by revenue, generating $403.4B annually — 543.0x EBS's $743M. MRK is the more profitable business, keeping 28.1% of every revenue dollar as net income compared to MCK's 1.2%. On growth, JNJ holds the edge at +6.8% YoY revenue growth, suggesting stronger near-term business momentum.

MetricEBS logoEBSEmergent BioSolut…JNJ logoJNJJohnson & JohnsonPFE logoPFEPfizer Inc.MRK logoMRKMerck & Co., Inc.MCK logoMCKMcKesson Corporat…
RevenueTrailing 12 months$743M$92.1B$63.3B$64.9B$403.4B
EBITDAEarnings before interest/tax$207M$31.4B$21.0B$32.4B$6.8B
Net IncomeAfter-tax profit$53M$25.1B$7.5B$18.3B$4.8B
Free Cash FlowCash after capex$157M$19.1B$9.5B$12.4B$6.0B
Gross MarginGross profit ÷ Revenue+47.1%+68.1%+69.3%+74.2%+3.6%
Operating MarginEBIT ÷ Revenue+14.7%+26.1%+23.4%+41.1%+1.5%
Net MarginNet income ÷ Revenue+7.1%+27.3%+11.8%+28.1%+1.2%
FCF MarginFCF ÷ Revenue+21.1%+20.7%+15.0%+19.0%+1.5%
Rev. Growth (YoY)Latest quarter vs prior year-23.6%+6.8%+5.4%+4.5%+6.0%
EPS Growth (YoY)Latest quarter vs prior year-76.3%+91.0%-9.5%-19.6%+37.0%
MRK leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

EBS leads this category, winning 4 of 7 comparable metrics.

At 9.8x trailing earnings, EBS trades at a 74% valuation discount to JNJ's 38.4x P/E. Adjusting for growth (PEG ratio), MRK offers better value at 0.73x vs JNJ's 34.02x — a lower PEG means you pay less per unit of expected earnings growth.

MetricEBS logoEBSEmergent BioSolut…JNJ logoJNJJohnson & JohnsonPFE logoPFEPfizer Inc.MRK logoMRKMerck & Co., Inc.MCK logoMCKMcKesson Corporat…
Market CapShares × price$472M$536.2B$150.6B$277.3B$92.1B
Enterprise ValueMkt cap + debt − cash$838M$548.8B$216.9B$313.3B$93.8B
Trailing P/EPrice ÷ TTM EPS9.82x38.43x19.47x15.42x29.25x
Forward P/EPrice ÷ next-FY EPS est.29.23x19.12x8.66x21.69x16.66x
PEG RatioP/E ÷ EPS growth rate34.02x0.73x0.75x
EV / EBITDAEnterprise value multiple4.02x18.61x10.66x10.68x18.74x
Price / SalesMarket cap ÷ Revenue0.64x6.04x2.41x4.27x0.26x
Price / BookPrice ÷ Book value/share0.99x7.56x1.74x5.35x
Price / FCFMarket cap ÷ FCF3.01x27.02x16.60x22.44x17.63x
EBS leads this category, winning 4 of 7 comparable metrics.

Profitability & Efficiency

Evenly matched — EBS and MCK each lead in 3 of 9 comparable metrics.

MCK delivers a 3.0% return on equity — every $100 of shareholder capital generates $3 in annual profit, vs $8 for PFE. JNJ carries lower financial leverage with a 0.51x debt-to-equity ratio, signaling a more conservative balance sheet compared to EBS's 1.09x. On the Piotroski fundamental quality scale (0–9), EBS scores 7/9 vs MRK's 4/9, reflecting strong financial health.

MetricEBS logoEBSEmergent BioSolut…JNJ logoJNJJohnson & JohnsonPFE logoPFEPfizer Inc.MRK logoMRKMerck & Co., Inc.MCK logoMCKMcKesson Corporat…
ROE (TTM)Return on equity+9.6%+31.7%+8.3%+36.1%+3.0%
ROA (TTM)Return on assets+3.7%+13.0%+3.6%+14.6%+5.7%
ROICReturn on invested capital+8.5%+20.7%+7.5%+22.0%+5.4%
ROCEReturn on capital employed+9.1%+17.6%+9.0%+23.8%+30.5%
Piotroski ScoreFundamental quality 0–975746
Debt / EquityFinancial leverage1.09x0.51x0.78x0.96x
Net DebtTotal debt minus cash$367M$12.5B$66.3B$36.0B$1.7B
Cash & Equiv.Liquid assets$205M$24.1B$1.1B$14.6B$5.7B
Total DebtShort + long-term debt$572M$36.6B$67.4B$50.5B$7.4B
Interest CoverageEBIT ÷ Interest expense1.84x48.23x4.02x19.68x33.79x
Evenly matched — EBS and MCK each lead in 3 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

MCK leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in MCK five years ago would be worth $38,689 today (with dividends reinvested), compared to $1,482 for EBS. Over the past 12 months, EBS leads with a +92.7% total return vs MCK's +4.6%. The 3-year compound annual growth rate (CAGR) favors MCK at 27.3% vs PFE's -6.6% — a key indicator of consistent wealth creation.

MetricEBS logoEBSEmergent BioSolut…JNJ logoJNJJohnson & JohnsonPFE logoPFEPfizer Inc.MRK logoMRKMerck & Co., Inc.MCK logoMCKMcKesson Corporat…
YTD ReturnYear-to-date-27.0%+7.9%+6.9%+6.3%-8.5%
1-Year ReturnPast 12 months+92.7%+44.8%+23.7%+46.1%+4.6%
3-Year ReturnCumulative with dividends+0.2%+46.3%-18.4%+2.9%+106.4%
5-Year ReturnCumulative with dividends-85.2%+46.1%-13.3%+70.2%+286.9%
10-Year ReturnCumulative with dividends-76.6%+132.3%+29.6%+166.5%+348.1%
CAGR (3Y)Annualised 3-year return+0.1%+13.5%-6.6%+0.9%+27.3%
MCK leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — PFE and MCK each lead in 1 of 2 comparable metrics.

MCK is the less volatile stock with a 0.04 beta — it tends to amplify market swings less than EBS's 1.83 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. PFE currently trades 92.1% from its 52-week high vs EBS's 65.0% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricEBS logoEBSEmergent BioSolut…JNJ logoJNJJohnson & JohnsonPFE logoPFEPfizer Inc.MRK logoMRKMerck & Co., Inc.MCK logoMCKMcKesson Corporat…
Beta (5Y)Sensitivity to S&P 5001.68x0.04x0.49x0.45x-0.02x
52-Week HighHighest price in past year$14.06$251.71$28.75$125.14$999.00
52-Week LowLowest price in past year$4.72$146.12$21.97$73.31$637.00
% of 52W HighCurrent price vs 52-week peak+65.0%+88.4%+92.1%+89.7%+75.3%
RSI (14)Momentum oscillator 0–10061.437.144.246.716.2
Avg Volume (50D)Average daily shares traded873K7.0M33.3M7.3M757K
Evenly matched — PFE and MCK each lead in 1 of 2 comparable metrics.

Analyst Outlook

Evenly matched — JNJ and PFE each lead in 1 of 2 comparable metrics.

Analyst consensus: EBS as "Buy", JNJ as "Buy", PFE as "Hold", MRK as "Buy", MCK as "Buy". Consensus price targets imply 32.2% upside for MCK (target: $995) vs 3.5% for PFE (target: $27). For income investors, PFE offers the higher dividend yield at 6.49% vs MCK's 0.36%.

MetricEBS logoEBSEmergent BioSolut…JNJ logoJNJJohnson & JohnsonPFE logoPFEPfizer Inc.MRK logoMRKMerck & Co., Inc.MCK logoMCKMcKesson Corporat…
Analyst RatingConsensus buy/hold/sellBuyBuyHoldBuyBuy
Price TargetConsensus 12-month target$12.00$249.27$27.40$129.31$994.86
# AnalystsCovering analysts1540393731
Dividend YieldAnnual dividend ÷ price+2.2%+6.5%+2.9%+0.4%
Dividend StreakConsecutive years of raises136151417
Dividend / ShareAnnual DPS$4.87$1.72$3.26$2.69
Buyback YieldShare repurchases ÷ mkt cap+5.3%+0.5%0.0%+1.8%+3.4%
Evenly matched — JNJ and PFE each lead in 1 of 2 comparable metrics.
Key Takeaway

MRK leads in 1 of 6 categories (Income & Cash Flow). EBS leads in 1 (Valuation Metrics). 3 tied.

Best OverallEmergent BioSolutions Inc. (EBS)Leads 1 of 6 categories
Loading custom metrics...

EBS vs JNJ vs PFE vs MRK vs MCK: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is EBS or JNJ or PFE or MRK or MCK a better buy right now?

For growth investors, McKesson Corporation (MCK) is the stronger pick with 16.

2% revenue growth year-over-year, versus -28. 8% for Emergent BioSolutions Inc. (EBS). Emergent BioSolutions Inc. (EBS) offers the better valuation at 9. 8x trailing P/E (29. 2x forward), making it the more compelling value choice. Analysts rate Emergent BioSolutions Inc. (EBS) a "Buy" — based on 15 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — EBS or JNJ or PFE or MRK or MCK?

On trailing P/E, Emergent BioSolutions Inc.

(EBS) is the cheapest at 9. 8x versus Johnson & Johnson at 38. 4x. On forward P/E, Pfizer Inc. is actually cheaper at 8. 7x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: McKesson Corporation wins at 0. 43x versus Johnson & Johnson's 34. 02x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.

03

Which is the better long-term investment — EBS or JNJ or PFE or MRK or MCK?

Over the past 5 years, McKesson Corporation (MCK) delivered a total return of +286.

9%, compared to -85. 2% for Emergent BioSolutions Inc. (EBS). Over 10 years, the gap is even starker: MCK returned +339. 0% versus EBS's -75. 7%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — EBS or JNJ or PFE or MRK or MCK?

By beta (market sensitivity over 5 years), McKesson Corporation (MCK) is the lower-risk stock at -0.

02β versus Emergent BioSolutions Inc. 's 1. 68β — meaning EBS is approximately -10355% more volatile than MCK relative to the S&P 500. On balance sheet safety, Johnson & Johnson (JNJ) carries a lower debt/equity ratio of 51% versus 109% for Emergent BioSolutions Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — EBS or JNJ or PFE or MRK or MCK?

By revenue growth (latest reported year), McKesson Corporation (MCK) is pulling ahead at 16.

2% versus -28. 8% for Emergent BioSolutions Inc. (EBS). On earnings-per-share growth, the picture is similar: Emergent BioSolutions Inc. grew EPS 125. 8% year-over-year, compared to -57. 8% for Johnson & Johnson. Over a 3-year CAGR, MCK leads at 10. 8% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — EBS or JNJ or PFE or MRK or MCK?

Merck & Co.

, Inc. (MRK) is the more profitable company, earning 28. 1% net margin versus 0. 9% for McKesson Corporation — meaning it keeps 28. 1% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: MRK leads at 36. 2% versus 1. 2% for MCK. At the gross margin level — before operating expenses — MRK leads at 72. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is EBS or JNJ or PFE or MRK or MCK more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, McKesson Corporation (MCK) is the more undervalued stock at a PEG of 0. 43x versus Johnson & Johnson's 34. 02x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Pfizer Inc. (PFE) trades at 8. 7x forward P/E versus 29. 2x for Emergent BioSolutions Inc. — 20. 6x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for MCK: 32. 2% to $994. 86.

08

Which pays a better dividend — EBS or JNJ or PFE or MRK or MCK?

In this comparison, PFE (6.

5% yield), MRK (2. 9% yield), JNJ (2. 2% yield), MCK (0. 4% yield) pay a dividend. EBS does not pay a meaningful dividend and should not be held primarily for income.

09

Is EBS or JNJ or PFE or MRK or MCK better for a retirement portfolio?

For long-horizon retirement investors, Johnson & Johnson (JNJ) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

04), 2. 2% yield, +131. 3% 10Y return). Emergent BioSolutions Inc. (EBS) carries a higher beta of 1. 68 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (JNJ: +131. 3%, EBS: -75. 7%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between EBS and JNJ and PFE and MRK and MCK?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: EBS is a small-cap deep-value stock; JNJ is a large-cap quality compounder stock; PFE is a mid-cap income-oriented stock; MRK is a large-cap deep-value stock; MCK is a mid-cap high-growth stock. JNJ, PFE, MRK pay a dividend while EBS, MCK do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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EBS

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Net Margin > 5%
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JNJ

Dividend Mega-Cap Quality

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 5%
  • Net Margin > 16%
Run This Screen
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PFE

Income & Dividend Stock

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 5%
  • Net Margin > 7%
Run This Screen
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MRK

Dividend Mega-Cap Quality

  • Sector: Healthcare
  • Market Cap > $100B
  • Net Margin > 16%
  • Dividend Yield > 1.1%
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MCK

Stable Dividend Mega-Cap

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 5%
  • Dividend Yield > 0.5%
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Beat Both

Find stocks that outperform EBS and JNJ and PFE and MRK and MCK on the metrics below

Revenue Growth>
%
(EBS: -23.6% · JNJ: 6.8%)
Net Margin>
%
(EBS: 7.1% · JNJ: 27.3%)
P/E Ratio<
x
(EBS: 9.8x · JNJ: 38.4x)

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