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Stock Comparison

ETON vs KALA vs LNTH vs RCKT

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
ETON
Eton Pharmaceuticals, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$839M
5Y Perf.+574.3%
KALA
KALA BIO, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$618K
5Y Perf.-100.0%
LNTH
Lantheus Holdings, Inc.

Drug Manufacturers - Specialty & Generic

HealthcareNASDAQ • US
Market Cap$5.92B
5Y Perf.+562.8%
RCKT
Rocket Pharmaceuticals, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$398M
5Y Perf.-80.5%

ETON vs KALA vs LNTH vs RCKT — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
ETON logoETON
KALA logoKALA
LNTH logoLNTH
RCKT logoRCKT
IndustryBiotechnologyBiotechnologyDrug Manufacturers - Specialty & GenericBiotechnology
Market Cap$839M$618K$5.92B$398M
Revenue (TTM)$80M$254K$1.55B$0.00
Net Income (TTM)$-5M$-36M$279M$-223M
Gross Margin53.5%-3.1%60.5%
Operating Margin-1.1%-150.6%18.8%
Forward P/E37.4x17.5x
Total Debt$9M$32M$738K$25M
Cash & Equiv.$26M$51M$359M$78M

ETON vs KALA vs LNTH vs RCKTLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

ETON
KALA
LNTH
RCKT
StockMay 20May 26Return
Eton Pharmaceutical… (ETON)100674.3+574.3%
KALA BIO, Inc. (KALA)1000.0-100.0%
Lantheus Holdings, … (LNTH)100662.8+562.8%
Rocket Pharmaceutic… (RCKT)10019.5-80.5%

Price return only. Dividends and distributions are not included.

Quick Verdict: ETON vs KALA vs LNTH vs RCKT

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: LNTH leads in 4 of 7 categories, making it the strongest pick for valuation and capital efficiency and profitability and margin quality. Eton Pharmaceuticals, Inc. is the stronger pick specifically for recent price momentum and sentiment. KALA also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
ETON
Eton Pharmaceuticals, Inc.
The Income Pick

ETON is the #2 pick in this set and the best alternative if income & stability is your priority.

  • Dividend streak 1 yrs, beta 0.66
  • +80.0% vs KALA's -97.6%
Best for: income & stability
KALA
KALA BIO, Inc.
The Growth Play

KALA is the clearest fit if your priority is growth exposure.

  • Rev growth 262.9%, EPS growth 59.8%
  • 262.9% revenue growth vs LNTH's 0.5%
Best for: growth exposure
LNTH
Lantheus Holdings, Inc.
The Long-Run Compounder

LNTH carries the broadest edge in this set and is the clearest fit for long-term compounding and sleep-well-at-night.

  • 41.9% 10Y total return vs ETON's 396.3%
  • Lower volatility, beta 0.47, Low D/E 0.1%, current ratio 2.70x
  • Beta 0.47, current ratio 2.70x
  • Better valuation composite
Best for: long-term compounding and sleep-well-at-night
RCKT
Rocket Pharmaceuticals, Inc.
The Secondary Option

RCKT lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
See the full category breakdown
CategoryWinnerWhy
GrowthKALA logoKALA262.9% revenue growth vs LNTH's 0.5%
ValueLNTH logoLNTHBetter valuation composite
Quality / MarginsLNTH logoLNTH18.0% margin vs KALA's -141.1%
Stability / SafetyLNTH logoLNTHBeta 0.47 vs KALA's 2.09, lower leverage
DividendsTieNone of these 4 stocks pay a meaningful dividend
Momentum (1Y)ETON logoETON+80.0% vs KALA's -97.6%
Efficiency (ROA)LNTH logoLNTH12.4% ROA vs KALA's -143.2%

ETON vs KALA vs LNTH vs RCKT — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

ETONEton Pharmaceuticals, Inc.
FY 2025
Product Sales and Royalties
95.9%$77M
License
4.1%$3M
KALAKALA BIO, Inc.

Segment breakdown not available.

LNTHLantheus Holdings, Inc.
FY 2025
Product
33.4%$1.5B
Radiopharmaceutical Oncology
21.9%$989M
PYLARIFY
21.9%$989M
Total Precision Diagnostics
10.9%$493M
DEFINITY
7.3%$330M
Techne Lite
1.9%$87M
Strategic Partnerships And Other
1.3%$59M
Other (2)
1.3%$59M
RCKTRocket Pharmaceuticals, Inc.

Segment breakdown not available.

ETON vs KALA vs LNTH vs RCKT — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLLNTHLAGGINGRCKT

Income & Cash Flow (Last 12 Months)

LNTH leads this category, winning 4 of 6 comparable metrics.

LNTH and RCKT operate at a comparable scale, with $1.5B and $0 in trailing revenue. LNTH is the more profitable business, keeping 18.0% of every revenue dollar as net income compared to KALA's -141.1%. On growth, ETON holds the edge at +82.7% YoY revenue growth, suggesting stronger near-term business momentum.

MetricETON logoETONEton Pharmaceutic…KALA logoKALAKALA BIO, Inc.LNTH logoLNTHLantheus Holdings…RCKT logoRCKTRocket Pharmaceut…
RevenueTrailing 12 months$80M$254,000$1.5B$0
EBITDAEarnings before interest/tax$2M-$38M$347M-$232M
Net IncomeAfter-tax profit-$5M-$36M$279M-$223M
Free Cash FlowCash after capex-$333,000-$32M$372M-$190M
Gross MarginGross profit ÷ Revenue+53.5%-3.1%+60.5%
Operating MarginEBIT ÷ Revenue-1.1%-150.6%+18.8%
Net MarginNet income ÷ Revenue-5.8%-141.1%+18.0%
FCF MarginFCF ÷ Revenue-0.4%-126.3%+24.0%
Rev. Growth (YoY)Latest quarter vs prior year+82.7%+1.2%
EPS Growth (YoY)Latest quarter vs prior year+3.4%+44.6%+76.5%+38.7%
LNTH leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

LNTH leads this category, winning 3 of 5 comparable metrics.
MetricETON logoETONEton Pharmaceutic…KALA logoKALAKALA BIO, Inc.LNTH logoLNTHLantheus Holdings…RCKT logoRCKTRocket Pharmaceut…
Market CapShares × price$839M$617,676$5.9B$398M
Enterprise ValueMkt cap + debt − cash$822M-$18M$5.6B$345M
Trailing P/EPrice ÷ TTM EPS-182.47x-0.01x26.69x-1.83x
Forward P/EPrice ÷ next-FY EPS est.37.37x17.52x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple14.61x
Price / SalesMarket cap ÷ Revenue10.49x3.84x
Price / BookPrice ÷ Book value/share31.91x0.04x5.72x1.47x
Price / FCFMarket cap ÷ FCF82.33x16.73x
LNTH leads this category, winning 3 of 5 comparable metrics.

Profitability & Efficiency

LNTH leads this category, winning 9 of 9 comparable metrics.

LNTH delivers a 24.3% return on equity — every $100 of shareholder capital generates $24 in annual profit, vs $-4 for KALA. LNTH carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to KALA's 2.62x. On the Piotroski fundamental quality scale (0–9), ETON scores 5/9 vs RCKT's 1/9, reflecting solid financial health.

MetricETON logoETONEton Pharmaceutic…KALA logoKALAKALA BIO, Inc.LNTH logoLNTHLantheus Holdings…RCKT logoRCKTRocket Pharmaceut…
ROE (TTM)Return on equity-18.8%-3.9%+24.3%-80.5%
ROA (TTM)Return on assets-4.8%-143.2%+12.4%-67.5%
ROICReturn on invested capital-2.6%+30.6%-63.2%
ROCEReturn on capital employed-1.5%-95.2%+17.1%-58.9%
Piotroski ScoreFundamental quality 0–95251
Debt / EquityFinancial leverage0.35x2.62x0.00x0.09x
Net DebtTotal debt minus cash-$17M-$19M-$358M-$53M
Cash & Equiv.Liquid assets$26M$51M$359M$78M
Total DebtShort + long-term debt$9M$32M$738,000$25M
Interest CoverageEBIT ÷ Interest expense-1.07x-6.92x11.72x
LNTH leads this category, winning 9 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

ETON leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in LNTH five years ago would be worth $41,420 today (with dividends reinvested), compared to $3 for KALA. Over the past 12 months, ETON leads with a +80.0% total return vs KALA's -97.6%. The 3-year compound annual growth rate (CAGR) favors ETON at 107.5% vs KALA's -82.6% — a key indicator of consistent wealth creation.

MetricETON logoETONEton Pharmaceutic…KALA logoKALAKALA BIO, Inc.LNTH logoLNTHLantheus Holdings…RCKT logoRCKTRocket Pharmaceut…
YTD ReturnYear-to-date+90.8%-86.6%+35.3%+6.1%
1-Year ReturnPast 12 months+80.0%-97.6%+13.1%-45.2%
3-Year ReturnCumulative with dividends+793.9%-99.5%-4.0%-82.8%
5-Year ReturnCumulative with dividends+292.2%-100.0%+314.2%-91.6%
10-Year ReturnCumulative with dividends+396.3%-100.0%+4192.5%-91.3%
CAGR (3Y)Annualised 3-year return+107.5%-82.6%-1.4%-44.4%
ETON leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

LNTH leads this category, winning 2 of 2 comparable metrics.

LNTH is the less volatile stock with a 0.47 beta — it tends to amplify market swings less than KALA's 2.09 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. LNTH currently trades 97.8% from its 52-week high vs KALA's 0.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricETON logoETONEton Pharmaceutic…KALA logoKALAKALA BIO, Inc.LNTH logoLNTHLantheus Holdings…RCKT logoRCKTRocket Pharmaceut…
Beta (5Y)Sensitivity to S&P 5000.66x2.09x0.47x1.31x
52-Week HighHighest price in past year$32.30$20.60$93.00$7.39
52-Week LowLowest price in past year$13.09$0.08$47.25$2.19
% of 52W HighCurrent price vs 52-week peak+96.0%+0.4%+97.8%+49.7%
RSI (14)Momentum oscillator 0–10071.730.161.254.4
Avg Volume (50D)Average daily shares traded392K9.2M886K3.5M
LNTH leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

ETON leads this category, winning 1 of 1 comparable metric.

Analyst consensus: ETON as "Buy", KALA as "Buy", LNTH as "Buy", RCKT as "Buy". Consensus price targets imply 21861.5% upside for KALA (target: $18) vs -19.4% for ETON (target: $25).

MetricETON logoETONEton Pharmaceutic…KALA logoKALAKALA BIO, Inc.LNTH logoLNTHLantheus Holdings…RCKT logoRCKTRocket Pharmaceut…
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuy
Price TargetConsensus 12-month target$25.00$18.25$101.00$5.00
# AnalystsCovering analysts691719
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises10
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%+5.1%0.0%
ETON leads this category, winning 1 of 1 comparable metric.
Key Takeaway

LNTH leads in 4 of 6 categories (Income & Cash Flow, Valuation Metrics). ETON leads in 2 (Total Returns, Analyst Outlook).

Best OverallLantheus Holdings, Inc. (LNTH)Leads 4 of 6 categories
Loading custom metrics...

ETON vs KALA vs LNTH vs RCKT: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is ETON or KALA or LNTH or RCKT a better buy right now?

For growth investors, Eton Pharmaceuticals, Inc.

(ETON) is the stronger pick with 104. 9% revenue growth year-over-year, versus 0. 5% for Lantheus Holdings, Inc. (LNTH). Lantheus Holdings, Inc. (LNTH) offers the better valuation at 26. 7x trailing P/E (17. 5x forward), making it the more compelling value choice. Analysts rate Eton Pharmaceuticals, Inc. (ETON) a "Buy" — based on 6 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — ETON or KALA or LNTH or RCKT?

On forward P/E, Lantheus Holdings, Inc.

is actually cheaper at 17. 5x.

03

Which is the better long-term investment — ETON or KALA or LNTH or RCKT?

Over the past 5 years, Lantheus Holdings, Inc.

(LNTH) delivered a total return of +314. 2%, compared to -100. 0% for KALA BIO, Inc. (KALA). Over 10 years, the gap is even starker: LNTH returned +41. 9% versus KALA's -100. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — ETON or KALA or LNTH or RCKT?

By beta (market sensitivity over 5 years), Lantheus Holdings, Inc.

(LNTH) is the lower-risk stock at 0. 47β versus KALA BIO, Inc. 's 2. 09β — meaning KALA is approximately 346% more volatile than LNTH relative to the S&P 500. On balance sheet safety, Lantheus Holdings, Inc. (LNTH) carries a lower debt/equity ratio of 0% versus 3% for KALA BIO, Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — ETON or KALA or LNTH or RCKT?

By revenue growth (latest reported year), Eton Pharmaceuticals, Inc.

(ETON) is pulling ahead at 104. 9% versus 0. 5% for Lantheus Holdings, Inc. (LNTH). On earnings-per-share growth, the picture is similar: KALA BIO, Inc. grew EPS 59. 8% year-over-year, compared to -21. 8% for Lantheus Holdings, Inc.. Over a 3-year CAGR, ETON leads at 55. 5% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — ETON or KALA or LNTH or RCKT?

Lantheus Holdings, Inc.

(LNTH) is the more profitable company, earning 15. 2% net margin versus -141. 1% for KALA BIO, Inc. — meaning it keeps 15. 2% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: LNTH leads at 20. 2% versus -150. 6% for KALA. At the gross margin level — before operating expenses — LNTH leads at 61. 1%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is ETON or KALA or LNTH or RCKT more undervalued right now?

On forward earnings alone, Lantheus Holdings, Inc.

(LNTH) trades at 17. 5x forward P/E versus 37. 4x for Eton Pharmaceuticals, Inc. — 19. 9x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for KALA: 21861. 5% to $18. 25.

08

Which pays a better dividend — ETON or KALA or LNTH or RCKT?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

09

Is ETON or KALA or LNTH or RCKT better for a retirement portfolio?

For long-horizon retirement investors, Eton Pharmaceuticals, Inc.

(ETON) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 66), +396. 3% 10Y return). KALA BIO, Inc. (KALA) carries a higher beta of 2. 09 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ETON: +396. 3%, KALA: -100. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between ETON and KALA and LNTH and RCKT?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: ETON is a small-cap high-growth stock; KALA is a small-cap quality compounder stock; LNTH is a small-cap quality compounder stock; RCKT is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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