Biotechnology
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EVAX vs IOVA
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
EVAX vs IOVA — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||
|---|---|---|
| Industry | Biotechnology | Biotechnology |
| Market Cap | $26M | $1.27B |
| Revenue (TTM) | $8M | $286M |
| Net Income (TTM) | $-8M | $-354M |
| Gross Margin | 99.7% | 114.5% |
| Operating Margin | -122.7% | -127.2% |
| Total Debt | $8M | $48M |
| Cash & Equiv. | $23M | $163M |
EVAX vs IOVA — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Feb 21 | May 26 | Return |
|---|---|---|---|
| Evaxion Biotech A/S (EVAX) | 100 | 1.2 | -98.8% |
| Iovance Biotherapeu… (IOVA) | 100 | 9.5 | -90.5% |
Price return only. Dividends and distributions are not included.
Quick Verdict: EVAX vs IOVA
Each card shows where this stock fits in a portfolio — not just who wins on paper.
EVAX carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- beta 1.29
- Rev growth 125.8%, EPS growth 87.7%
- Lower volatility, beta 1.29, Low D/E 44.0%, current ratio 5.85x
IOVA is the clearest fit if your priority is long-term compounding.
- -34.3% 10Y total return vs EVAX's -99.2%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 125.8% revenue growth vs IOVA's 60.6% | |
| Quality / Margins | -102.4% margin vs IOVA's -123.9% | |
| Stability / Safety | Beta 1.29 vs IOVA's 2.01 | |
| Dividends | Tie | Neither stock pays a meaningful dividend |
| Momentum (1Y) | +175.0% vs IOVA's +13.4% | |
| Efficiency (ROA) | -29.2% ROA vs IOVA's -38.8%, ROIC -295.2% vs -48.9% |
EVAX vs IOVA — Financial Metrics
Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.
Income & Cash Flow (Last 12 Months)
EVAX leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
IOVA is the larger business by revenue, generating $286M annually — 37.8x EVAX's $8M. EVAX is the more profitable business, keeping -102.4% of every revenue dollar as net income compared to IOVA's -123.9%. On growth, IOVA holds the edge at +44.8% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||
|---|---|---|
| RevenueTrailing 12 months | $8M | $286M |
| EBITDAEarnings before interest/tax | -$4M | -$330M |
| Net IncomeAfter-tax profit | -$8M | -$354M |
| Free Cash FlowCash after capex | -$7M | -$305M |
| Gross MarginGross profit ÷ Revenue | +99.7% | +114.5% |
| Operating MarginEBIT ÷ Revenue | -122.7% | -127.2% |
| Net MarginNet income ÷ Revenue | -102.4% | -123.9% |
| FCF MarginFCF ÷ Revenue | -88.2% | -106.8% |
| Rev. Growth (YoY)Latest quarter vs prior year | -81.9% | +44.8% |
| EPS Growth (YoY)Latest quarter vs prior year | +73.8% | +47.2% |
Valuation Metrics
EVAX leads this category, winning 3 of 3 comparable metrics.
Valuation Metrics
| Metric | ||
|---|---|---|
| Market CapShares × price | $26M | $1.3B |
| Enterprise ValueMkt cap + debt − cash | $10M | $1.2B |
| Trailing P/EPrice ÷ TTM EPS | -3.36x | -3.26x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — |
| EV / EBITDAEnterprise value multiple | — | — |
| Price / SalesMarket cap ÷ Revenue | 3.40x | 4.82x |
| Price / BookPrice ÷ Book value/share | 1.53x | 1.82x |
| Price / FCFMarket cap ÷ FCF | — | — |
Profitability & Efficiency
IOVA leads this category, winning 6 of 8 comparable metrics.
Profitability & Efficiency
IOVA delivers a -50.2% return on equity — every $100 of shareholder capital generates $-50 in annual profit, vs $-62 for EVAX. IOVA carries lower financial leverage with a 0.07x debt-to-equity ratio, signaling a more conservative balance sheet compared to EVAX's 0.44x. On the Piotroski fundamental quality scale (0–9), IOVA scores 5/9 vs EVAX's 4/9, reflecting solid financial health.
| Metric | ||
|---|---|---|
| ROE (TTM)Return on equity | -61.6% | -50.2% |
| ROA (TTM)Return on assets | -29.2% | -38.8% |
| ROICReturn on invested capital | -3.0% | -48.9% |
| ROCEReturn on capital employed | -57.4% | -51.6% |
| Piotroski ScoreFundamental quality 0–9 | 4 | 5 |
| Debt / EquityFinancial leverage | 0.44x | 0.07x |
| Net DebtTotal debt minus cash | -$16M | -$115M |
| Cash & Equiv.Liquid assets | $23M | $163M |
| Total DebtShort + long-term debt | $8M | $48M |
| Interest CoverageEBIT ÷ Interest expense | -10.54x | — |
Total Returns (Dividends Reinvested)
IOVA leads this category, winning 5 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in IOVA five years ago would be worth $1,245 today (with dividends reinvested), compared to $123 for EVAX. Over the past 12 months, EVAX leads with a +175.0% total return vs IOVA's +13.4%. The 3-year compound annual growth rate (CAGR) favors IOVA at -20.6% vs EVAX's -62.0% — a key indicator of consistent wealth creation.
| Metric | ||
|---|---|---|
| YTD ReturnYear-to-date | -13.6% | +40.9% |
| 1-Year ReturnPast 12 months | +175.0% | +13.4% |
| 3-Year ReturnCumulative with dividends | -94.5% | -49.9% |
| 5-Year ReturnCumulative with dividends | -98.8% | -87.6% |
| 10-Year ReturnCumulative with dividends | -99.2% | -34.3% |
| CAGR (3Y)Annualised 3-year return | -62.0% | -20.6% |
Risk & Volatility
Evenly matched — EVAX and IOVA each lead in 1 of 2 comparable metrics.
Risk & Volatility
EVAX is the less volatile stock with a 1.29 beta — it tends to amplify market swings less than IOVA's 2.01 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IOVA currently trades 63.1% from its 52-week high vs EVAX's 33.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.29x | 2.01x |
| 52-Week HighHighest price in past year | $12.15 | $5.63 |
| 52-Week LowLowest price in past year | $1.43 | $1.64 |
| % of 52W HighCurrent price vs 52-week peak | +33.5% | +63.1% |
| RSI (14)Momentum oscillator 0–100 | 56.5 | 63.1 |
| Avg Volume (50D)Average daily shares traded | 32K | 16.2M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
| Metric | ||
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy |
| Price TargetConsensus 12-month target | — | $2.00 |
| # AnalystsCovering analysts | — | 20 |
| Dividend YieldAnnual dividend ÷ price | — | — |
| Dividend StreakConsecutive years of raises | — | 1 |
| Dividend / ShareAnnual DPS | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% |
EVAX leads in 2 of 6 categories (Income & Cash Flow, Valuation Metrics). IOVA leads in 2 (Profitability & Efficiency, Total Returns). 1 tied.
EVAX vs IOVA: Frequently Asked Questions
8 questions · data-driven answers · updated daily
01Is EVAX or IOVA a better buy right now?
For growth investors, Evaxion Biotech A/S (EVAX) is the stronger pick with 125.
8% revenue growth year-over-year, versus 60. 6% for Iovance Biotherapeutics, Inc. (IOVA). Analysts rate Iovance Biotherapeutics, Inc. (IOVA) a "Buy" — based on 20 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — EVAX or IOVA?
Over the past 5 years, Iovance Biotherapeutics, Inc.
(IOVA) delivered a total return of -87. 6%, compared to -98. 8% for Evaxion Biotech A/S (EVAX). Over 10 years, the gap is even starker: IOVA returned -34. 3% versus EVAX's -99. 2%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — EVAX or IOVA?
By beta (market sensitivity over 5 years), Evaxion Biotech A/S (EVAX) is the lower-risk stock at 1.
29β versus Iovance Biotherapeutics, Inc. 's 2. 01β — meaning IOVA is approximately 56% more volatile than EVAX relative to the S&P 500. On balance sheet safety, Iovance Biotherapeutics, Inc. (IOVA) carries a lower debt/equity ratio of 7% versus 44% for Evaxion Biotech A/S — giving it more financial flexibility in a downturn.
04Which is growing faster — EVAX or IOVA?
By revenue growth (latest reported year), Evaxion Biotech A/S (EVAX) is pulling ahead at 125.
8% versus 60. 6% for Iovance Biotherapeutics, Inc. (IOVA). On earnings-per-share growth, the picture is similar: Evaxion Biotech A/S grew EPS 87. 7% year-over-year, compared to 14. 8% for Iovance Biotherapeutics, Inc.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — EVAX or IOVA?
Evaxion Biotech A/S (EVAX) is the more profitable company, earning -102.
4% net margin versus -148. 4% for Iovance Biotherapeutics, Inc. — meaning it keeps -102. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: EVAX leads at -122. 7% versus -153. 1% for IOVA. At the gross margin level — before operating expenses — EVAX leads at 99. 7%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — EVAX or IOVA?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is EVAX or IOVA better for a retirement portfolio?
For long-horizon retirement investors, Evaxion Biotech A/S (EVAX) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1.
29)). Iovance Biotherapeutics, Inc. (IOVA) carries a higher beta of 2. 01 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (EVAX: -99. 2%, IOVA: -34. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between EVAX and IOVA?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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