EWTX
Edgewise Therapeutics, Inc.
Biotechnology
Market Cap$3.82B
5Y Perf.+9.5%
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Stock Comparison
EWTX vs CMPS
Revenue, margins, valuation, and 5-year total return — side by side.
CMPS
COMPASS Pathways plc
Medical - Care Facilities
Market Cap$902M
5Y Perf.-74.5%
EWTX vs CMPS — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | EWTX | CMPS |
|---|---|---|
| Industry | Biotechnology | Medical - Care Facilities |
| Market Cap | $3.82B | $902M |
| Revenue (TTM) | $0.00 | $0.00 |
| Net Income (TTM) | $-176M | $-288M |
| Total Debt | $4M | $21M |
| Cash & Equiv. | $61M | $150M |
EWTX vs CMPS — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
EWTX
CMPS
| Stock | Mar 21 | May 26 | Return |
|---|---|---|---|
| Edgewise Therapeuti… (EWTX) | 100 | 109.5 | +9.5% |
| COMPASS Pathways plc (CMPS) | 100 | 25.5 | -74.5% |
Price return only. Dividends and distributions are not included.
Quick Verdict: EWTX vs CMPS
Each card shows where this stock fits in a portfolio — not just who wins on paper.
Bottom line: EWTX leads in 4 of 6 categories, making it the strongest pick for growth and revenue expansion and profitability and margin quality. COMPASS Pathways plc is the stronger pick specifically for recent price momentum and sentiment. As sector peers, any of these can serve as alternatives in the same allocation.
EWTX
Edgewise Therapeutics, Inc.
The Income Pick
EWTX carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- beta 1.09
- EPS growth -12.4%
- 18.6% 10Y total return vs CMPS's -67.6%
Best for: income & stability and growth exposure
CMPS
COMPASS Pathways plc
The Momentum Pick
CMPS is the clearest fit if your priority is momentum.
- +151.1% vs EWTX's +145.0%
Best for: momentum
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | EWTX | -22.4% revenue growth vs CMPS's -85.7% |
| Quality / Margins | EWTX | 4.3% margin vs CMPS's 1.3% |
| Stability / Safety | EWTX | Beta 1.09 vs CMPS's 1.33 |
| Dividends | Tie | Neither stock pays a meaningful dividend |
| Momentum (1Y) | CMPS | +151.1% vs EWTX's +145.0% |
| Efficiency (ROA) | EWTX | -31.0% ROA vs CMPS's -106.8% |
EWTX vs CMPS — Financial Metrics
Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.
BEST OVERALLEWTXLAGGINGCMPS
CMPSCOMPASS Pathways plc
0leads
EWTXEdgewise Therapeutics…
4leads
6 Total Categories
CATEGORYLEADERvs CMPSMETRICS WON
Income & Cash FlowRevenue, margins, and cash flow strength
EWTX1/1
Valuation MetricsMultiples, price ratios, and targets
EWTX1/1
Profitability & EfficiencyROE, ROIC, leverage, and quality scores
EWTX5/6
Total Returns1Y, 3Y, 5Y total returns with dividends
EWTX5/6
Risk & VolatilityBeta, volatility, and downside exposure
Tied
—
Analyst OutlookRatings, price targets, and dividends
—
—
Income & Cash Flow (Last 12 Months)
EWTX leads this category, winning 1 of 1 comparable metric.
Income & Cash Flow (Last 12 Months)
EWTX and CMPS operate at a comparable scale, with $0 and $0 in trailing revenue.
| Metric | EWTXEdgewise Therapeu… | CMPSCOMPASS Pathways … |
|---|---|---|
| RevenueTrailing 12 months | $0 | $0 |
| EBITDAEarnings before interest/tax | -$200M | -$179M |
| Net IncomeAfter-tax profit | -$176M | -$288M |
| Free Cash FlowCash after capex | -$149M | -$157M |
| Gross MarginGross profit ÷ Revenue | — | — |
| Operating MarginEBIT ÷ Revenue | — | — |
| Net MarginNet income ÷ Revenue | — | — |
| FCF MarginFCF ÷ Revenue | — | — |
| Rev. Growth (YoY)Latest quarter vs prior year | — | — |
| EPS Growth (YoY)Latest quarter vs prior year | -7.0% | -58.7% |
EWTX leads this category, winning 1 of 1 comparable metric.
Valuation Metrics
EWTX leads this category, winning 1 of 1 comparable metric.
Valuation Metrics
| Metric | EWTXEdgewise Therapeu… | CMPSCOMPASS Pathways … |
|---|---|---|
| Market CapShares × price | $3.8B | $902M |
| Enterprise ValueMkt cap + debt − cash | $3.8B | $774M |
| Trailing P/EPrice ÷ TTM EPS | -21.83x | -3.05x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — |
| EV / EBITDAEnterprise value multiple | — | — |
| Price / SalesMarket cap ÷ Revenue | — | — |
| Price / BookPrice ÷ Book value/share | 7.01x | — |
| Price / FCFMarket cap ÷ FCF | — | — |
EWTX leads this category, winning 1 of 1 comparable metric.
Profitability & Efficiency
EWTX leads this category, winning 5 of 6 comparable metrics.
Profitability & Efficiency
EWTX delivers a -32.5% return on equity — every $100 of shareholder capital generates $-33 in annual profit, vs $-3 for CMPS. On the Piotroski fundamental quality scale (0–9), EWTX scores 3/9 vs CMPS's 2/9, reflecting mixed financial health.
| Metric | EWTXEdgewise Therapeu… | CMPSCOMPASS Pathways … |
|---|---|---|
| ROE (TTM)Return on equity | -32.5% | -3.4% |
| ROA (TTM)Return on assets | -31.0% | -106.8% |
| ROICReturn on invested capital | -32.4% | — |
| ROCEReturn on capital employed | -38.7% | -2.5% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 2 |
| Debt / EquityFinancial leverage | 0.01x | — |
| Net DebtTotal debt minus cash | -$57M | -$129M |
| Cash & Equiv.Liquid assets | $61M | $150M |
| Total DebtShort + long-term debt | $4M | $21M |
| Interest CoverageEBIT ÷ Interest expense | — | -52.40x |
EWTX leads this category, winning 5 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
EWTX leads this category, winning 5 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in EWTX five years ago would be worth $12,168 today (with dividends reinvested), compared to $2,756 for CMPS. Over the past 12 months, CMPS leads with a +151.1% total return vs EWTX's +145.0%. The 3-year compound annual growth rate (CAGR) favors EWTX at 53.3% vs CMPS's 3.5% — a key indicator of consistent wealth creation.
| Metric | EWTXEdgewise Therapeu… | CMPSCOMPASS Pathways … |
|---|---|---|
| YTD ReturnYear-to-date | +49.8% | +43.4% |
| 1-Year ReturnPast 12 months | +145.0% | +151.1% |
| 3-Year ReturnCumulative with dividends | +260.1% | +11.0% |
| 5-Year ReturnCumulative with dividends | +21.7% | -72.4% |
| 10-Year ReturnCumulative with dividends | +18.6% | -67.6% |
| CAGR (3Y)Annualised 3-year return | +53.3% | +3.5% |
EWTX leads this category, winning 5 of 6 comparable metrics.
Risk & Volatility
Evenly matched — EWTX and CMPS each lead in 1 of 2 comparable metrics.
Risk & Volatility
EWTX is the less volatile stock with a 1.09 beta — it tends to amplify market swings less than CMPS's 1.33 beta. A beta below 1.0 means the stock typically moves less than the S&P 500.
| Metric | EWTXEdgewise Therapeu… | CMPSCOMPASS Pathways … |
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.09x | 1.33x |
| 52-Week HighHighest price in past year | $39.96 | $10.21 |
| 52-Week LowLowest price in past year | $12.15 | $2.25 |
| % of 52W HighCurrent price vs 52-week peak | +89.0% | +92.0% |
| RSI (14)Momentum oscillator 0–100 | 66.1 | 68.1 |
| Avg Volume (50D)Average daily shares traded | 919K | 3.7M |
Evenly matched — EWTX and CMPS each lead in 1 of 2 comparable metrics.
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Wall Street rates EWTX as "Buy" and CMPS as "Buy". Consensus price targets imply 89.9% upside for CMPS (target: $18) vs 8.7% for EWTX (target: $39).
| Metric | EWTXEdgewise Therapeu… | CMPSCOMPASS Pathways … |
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy |
| Price TargetConsensus 12-month target | $38.67 | $17.83 |
| # AnalystsCovering analysts | 9 | 13 |
| Dividend YieldAnnual dividend ÷ price | — | — |
| Dividend StreakConsecutive years of raises | — | — |
| Dividend / ShareAnnual DPS | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% |
Insufficient data to determine a leader in this category.
Key Takeaway
EWTX leads in 4 of 6 categories — strongest in Income & Cash Flow and Valuation Metrics. 1 category is tied.
Best OverallEdgewise Therapeutics, Inc. (EWTX)Leads 4 of 6 categories
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EWTX vs CMPS: Frequently Asked Questions
8 questions · data-driven answers · updated daily
01Is EWTX or CMPS a better buy right now?
Analysts rate Edgewise Therapeutics, Inc.
(EWTX) a "Buy" — based on 9 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — EWTX or CMPS?
Over the past 5 years, Edgewise Therapeutics, Inc.
(EWTX) delivered a total return of +21. 7%, compared to -72. 4% for COMPASS Pathways plc (CMPS). Over 10 years, the gap is even starker: EWTX returned +18. 6% versus CMPS's -67. 6%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — EWTX or CMPS?
By beta (market sensitivity over 5 years), Edgewise Therapeutics, Inc.
(EWTX) is the lower-risk stock at 1. 09β versus COMPASS Pathways plc's 1. 33β — meaning CMPS is approximately 22% more volatile than EWTX relative to the S&P 500.
04Which is growing faster — EWTX or CMPS?
On earnings-per-share growth, the picture is similar: Edgewise Therapeutics, Inc.
grew EPS -12. 4% year-over-year, compared to -33. 9% for COMPASS Pathways plc. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — EWTX or CMPS?
Edgewise Therapeutics, Inc.
(EWTX) is the more profitable company, earning 0. 0% net margin versus 0. 0% for COMPASS Pathways plc — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: EWTX leads at 0. 0% versus 0. 0% for CMPS. At the gross margin level — before operating expenses — EWTX leads at 0. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — EWTX or CMPS?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is EWTX or CMPS better for a retirement portfolio?
For long-horizon retirement investors, Edgewise Therapeutics, Inc.
(EWTX) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 09)). Both have compounded well over 10 years (EWTX: +18. 6%, CMPS: -67. 6%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between EWTX and CMPS?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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