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EWTXEdgewise Therapeutics, Inc.
$36.81$4.0B
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EWTX logoEdgewise Therapeutics, Inc.(EWTX)Earnings, Financials & Key Ratios

EWTX•NASDAQ
Price updated Jun 19, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryCommercial Rare Disease Biopharma
AboutEdgewise Therapeutics, Inc., a biopharmaceutical company, develops small molecule therapies for musculoskeletal diseases. The Company's lead product candidate, EDG-5506, is an orally administered small molecule designed to address the root cause of dystrophinopathies including Duchenne muscular dystrophy and Becker muscular dystrophy which has completed Phase 1 clinical trial. It develops a pipeline of precision medicine product candidates that target key muscle proteins and modulators to address genetically defined muscle disorders. Edgewise Therapeutics, Inc. was incorporated in 2017 and is headquartered in Boulder, Colorado.Show more
  • Revenue$0
  • EBITDA-$189M-20.8%
  • Net Income-$168M-25.4%
  • EPS (Diluted)-1.63-12.4%
  • ROE-34.19%+0.6%

EWTX Key Insights

Edgewise Therapeutics, Inc. (EWTX) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Company is almost debt free
  • ✓Momentum leader: RS Rating 90 (top 10%)

✗Weaknesses

  • ✗Profits declining 58.0% over 5 years
  • ✗Weak Piotroski F-Score: 3/9
  • ✗Shares diluted 11.4% in last year
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

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EWTX Price & Volume

Edgewise Therapeutics, Inc. (EWTX) stock price & volume — 10-year historical chart

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EWTX Growth Metrics

Edgewise Therapeutics, Inc. (EWTX) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-20.48%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-7.1%

Return on Capital

10 Years-31.83%
5 Years-31.51%
3 Years-37.7%
Last Year-38.74%

EWTX Recent Earnings

Edgewise Therapeutics, Inc. (EWTX) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 8/12 qtrs (67%)
Q2 2026Latest
May 7, 2026
Metric
Actual
Est
EPS
$0.46+8.0%
$0.50
Rev
—
—
Q1 2026
Feb 26, 2026
Metric
Actual
Est
EPS
$0.47-9.3%
$0.43
Rev
—
—
Q4 2025
Nov 6, 2025
Metric
Actual
Est
EPS
$0.39+2.5%
$0.40
Rev
—
—
Q3 2025
Aug 7, 2025
Metric
Actual
Est
EPS
$0.34+19.0%
$0.42
Rev
—
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 7, 2026
$0.46vs $0.50+8.0%
—
Q1 2026Feb 26, 2026
$0.47vs $0.43-9.3%
—
Q4 2025Nov 6, 2025
$0.39vs $0.40+2.5%
—
Q3 2025Aug 7, 2025
$0.34vs $0.42+19.0%
—
Based on last 12 quarters of dataView full earnings history →

EWTX Peer Comparison

Edgewise Therapeutics, Inc. (EWTX) competitors in Commercial Rare Disease Biopharma — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
Institutional Holdings
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
ACAD logoACADACADIA Pharmaceuticals Inc.Direct Competitor3.7B21.629.4411.87%34.3%35.65%0.04
KYMR logoKYMRKymera Therapeutics, Inc.Direct Competitor7.38B90.43-24.51-16.72%-6.12%-25.02%0.05
CMPS logoCMPSCOMPASS Pathways plcDirect Competitor1.2B12.53-4.07-151.02%
IMVT logoIMVTImmunovant, Inc.Direct Competitor7.26B35.34-12.76-68.16%0.00
ARQT logoARQTArcutis Biotherapeutics, Inc.Direct Competitor3.28B26.21-201.6291.34%-0.57%-1.41%0.03
PRAX logoPRAXPraxis Precision Medicines, Inc.Direct Competitor8.15B282.31-20.94-100%-43.02%0.00
MGTX logoMGTXMeiraGTx Holdings plcProduct Competitor1.05B11.32-7.97144.57%-151.12%-368.19%
MDGL logoMDGLMadrigal Pharmaceuticals, Inc.Product Competitor11.66B505.75-39.36432.05%-27.32%-50.15%0.59

Compare EWTX vs Peers

Edgewise Therapeutics, Inc. (EWTX) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs ACAD

Most directly comparable listed peer for EWTX.

Scale Benchmark

vs ABBV

Larger-name benchmark to compare EWTX against a more recognizable public peer.

Peer Set

Compare Top 5

vs ACAD, KYMR, CMPS, IMVT

EWTX Income Statement

Edgewise Therapeutics, Inc. (EWTX) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
MetricDec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Sales/Revenue
00000000
Revenue Growth %
--------
Cost of Goods Sold
123K185K00002.27M590K
COGS % of Revenue
--------
Gross Profit
-123K▲ 0%
-185K▼ 50.4%
0▲ 100.0%
0▲ 0%
0▲ 0%
0▲ 0%
-2.27M▲ 0%
-590K▲ 0%
Gross Margin %
--------
Gross Profit Growth %
--50.41%100%-----
Operating Expenses
9.92M17.01M43.22M71.66M114.36M158.83M189.14M198.97M
OpEx % of Revenue
--------
Selling, General & Admin
1.3M2.21M11.03M17.63M23.45M31.87M40.02M42.28M
SG&A % of Revenue
--------
Research & Development
8.62M14.8M32.19M54.03M90.91M126.97M151.39M157.28M
R&D % of Revenue
--------
Other Operating Expenses
000000-2.27M-590K
Operating Income
-9.92M▲ 0%
-17.19M▼ 73.2%
-43.22M▼ 151.4%
-71.66M▼ 65.8%
-114.36M▼ 59.6%
-158.83M▼ 38.9%
-191.41M▼ 20.5%
-199.56M▲ 0%
Operating Margin %
--------
Operating Income Growth %
--73.24%-151.37%-65.82%-59.59%-38.89%-20.51%-
EBITDA
-9.8M-17.01M-42.94M-71.12M-112.63M-156.54M-189.14M-199.53M
EBITDA Margin %
--------
EBITDA Growth %
--73.52%-152.5%-65.61%-58.36%-38.99%-20.82%-18.96%
D&A (Non-Cash Add-back)
123K185K272K538K1.73M2.29M2.27M36K
EBIT
-9.92M-17.19M-43.22M-71.66M-114.36M-158.83M-167.79M-187.61M
Net Interest Income
219K69K402K-1.35M14.19M25.02M23.61M23.55M
Interest Income
219K69K402K2.66M14.19M25.02M23.61M23.55M
Interest Expense
0004.02M0000
Other Income/Expense
219K69K402K4.02M14.19M25.02M23.61M23.55M
Pretax Income
-9.71M▲ 0%
-17.12M▼ 76.4%
-42.81M▼ 150.0%
-67.64M▼ 58.0%
-100.16M▼ 48.1%
-133.81M▼ 33.6%
-167.79M▼ 25.4%
-176.01M▲ 0%
Pretax Margin %
--------
Income Tax
00000000
Effective Tax Rate %
0%0%0%0%0%0%0%0%
Net Income
-9.49M▲ 0%
-17.05M▼ 79.8%
-42.81M▼ 151.0%
-67.64M▼ 58.0%
-100.16M▼ 48.1%
-133.81M▼ 33.6%
-167.79M▼ 25.4%
-176.01M▲ 0%
Net Margin %
--------
Net Income Growth %
--79.78%-151.04%-57.99%-48.08%-33.6%-25.4%-20.48%
Net Income (Continuing)
-9.71M-17.12M-42.81M-67.64M-100.16M-133.81M-167.79M-176.01M
Discontinued Operations
00000000
Minority Interest
00000000
EPS (Diluted)
-0.19▲ 0%
-0.35▼ 84.2%
-0.86▼ 145.7%
-1.26▼ 46.5%
-1.57▼ 24.6%
-1.45▲ 7.6%
-1.63▼ 12.4%
-1.64▲ 0%
EPS Growth %
--84.21%-145.71%-46.51%-24.6%7.64%-12.41%-7.1%
EPS (Basic)
-0.19-0.35-0.86-1.26-1.57-1.45-1.63-
Diluted Shares Outstanding
49.22M49.22M49.5M53.59M63.72M92.41M102.93M107.12M
Basic Shares Outstanding
49.22M49.22M49.5M53.59M63.72M92.41M102.93M107.12M
Dividend Payout Ratio
--------

EWTX Balance Sheet

Edgewise Therapeutics, Inc. (EWTX) balance sheet — assets, liabilities & shareholders' equity

MetricDec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Total Current Assets
24.04M129.65M283.77M357M327M475.48M543.38M509.79M
Cash & Short-Term Investments
23.65M129.09M280.79M351.95M318.39M470.17M530.11M499.56M
Cash Only
23.65M104.92M15.57M21.99M86.1M41.67M61.15M33.21M
Short-Term Investments
024.18M265.22M329.95M232.3M428.5M468.96M466.35M
Accounts Receivable
00000000
Days Sales Outstanding
--------
Inventory
00000000
Days Inventory Outstanding
--------
Other Current Assets
00008.6M5.31M13.28M10.23M
Total Non-Current Assets
498K1.49M1.46M10.1M13.04M11.33M9.22M8.73M
Property, Plant & Equipment
498K516K912K9.85M12.69M11.07M9.22M8.73M
Fixed Asset Turnover
-------0.00x
Goodwill
00000000
Intangible Assets
00000000
Long-Term Investments
00000000
Other Non-Current Assets
0975K548K251K348K262K00
Total Assets
24.54M▲ 0%
131.14M▲ 434.4%
285.23M▲ 117.5%
367.1M▲ 28.7%
340.04M▼ 7.4%
486.82M▲ 43.2%
552.6M▲ 13.5%
518.52M▲ 0%
Asset Turnover
-------0.00x
Asset Growth %
-434.35%117.51%28.7%-7.37%43.17%13.51%57.11%
Total Current Liabilities
1.13M4.34M10.52M16.59M16.77M23.86M27.37M22.54M
Accounts Payable
667K1.58M3.84M6.11M4.03M5.58M6.01M7.29M
Days Payables Outstanding
1.98K3.12K----967.434.3K
Short-Term Debt
0000001.01M1.02M
Deferred Revenue (Current)
00000000
Other Current Liabilities
333K452K2.8M4.03M5.7M10.06M20.35M14.23M
Current Ratio
21.24x29.86x26.97x21.53x19.50x19.93x19.85x22.61x
Quick Ratio
21.24x29.86x26.97x21.53x19.50x19.93x19.85x22.61x
Cash Conversion Cycle
--------
Total Non-Current Liabilities
40.26M160.21M329K3.8M4.43M3.74M2.98M2.78M
Long-Term Debt
0160.21M00002.98M2.78M
Capital Lease Obligations
0003.8M4.43M3.74M03.37M
Deferred Tax Liabilities
00000000
Other Non-Current Liabilities
40.26M0329K00000
Total Liabilities
41.39M164.56M10.85M20.39M21.2M27.6M30.35M25.32M
Total Debt
0160.21M04.41M5.41M4.74M3.99M3.79M
Net Debt
-23.65M55.3M-15.57M-17.59M-80.68M-36.93M-57.16M-29.42M
Debt / Equity
---0.01x0.02x0.01x0.01x0.01x
Debt / EBITDA
--------0.02x
Net Debt / EBITDA
-------0.15x
Interest Coverage
----17.83x----
Total Equity
-16.85M▲ 0%
-33.42M▼ 98.3%
274.38M▲ 921.0%
346.72M▲ 26.4%
318.83M▼ 8.0%
459.22M▲ 44.0%
522.26M▲ 13.7%
493.2M▲ 0%
Equity Growth %
--98.3%921.01%26.36%-8.04%44.03%13.73%58.17%
Book Value per Share
-0.34-0.685.546.475.004.975.074.60
Total Shareholders' Equity
-16.85M-33.42M274.38M346.72M318.83M459.22M522.26M493.2M
Common Stock
005K6K7K9K10K10K
Retained Earnings
-17.02M-34.15M-76.96M-144.6M-244.76M-378.58M-546.37M-595.38M
Treasury Stock
00000000
Accumulated OCI
00-514K-1.35M99K420K677K-252K
Minority Interest
00000000

EWTX Cash Flow Statement

Edgewise Therapeutics, Inc. (EWTX) cash flow — operating, investing & free cash flow history

MetricDec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Cash from Operations
-9.17M-14.63M-33.51M-52.63M-91.95M-109.03M-143.82M-148.49M
Operating CF Margin %
--------
Operating CF Growth %
--59.57%-128.97%-57.09%-74.69%-18.58%-31.91%-107.39%
Net Income
-9.71M-17.12M-42.81M-67.64M-100.16M-133.81M-167.79M-176.01M
Depreciation & Amortization
123K185K272K538K1.73M2.29M2.27M36K
Stock-Based Compensation
77K354K4.4M10.92M17.56M24.71M0-9.06M
Deferred Taxes
00-2.29M00000
Other Non-Cash Items
002.29M-543K-9.52M-12.54M27.09M-130.95M
Working Capital Changes
334K1.95M4.63M4.09M-1.56M10.33M-5.37M-306K
Change in Receivables
00000000
Change in Inventory
00000000
Change in Payables
275K521K2.65M47K-92K1.74M272K992K
Cash from Investing
-180K-24.38M-242.23M-70.58M102.89M-184.66M-32.79M-74.25M
Capital Expenditures
-180K-203K-668K-5.55M-5.75M-1.31M-256K-216K
CapEx % of Revenue
--------
Acquisitions
00241.56K65.03K0000
Investments
--------
Other Investing
00-241.56K-65.03K0003.02M
Cash from Financing
24.8M120.28M186.38M129.64M53.17M249.25M196.09M206.04M
Debt Issued (Net)
00000000
Equity Issued (Net)
24.78M120.08M186.15M129.16M52.62M239.15M196.09M204.11M
Dividends Paid
00000000
Share Repurchases
00000000
Other Financing
22K202K236K474K548K10.11M01.93M
Net Change in Cash
15.45M▲ 0%
81.26M▲ 426.0%
-89.35M▼ 210.0%
6.43M▲ 107.2%
64.1M▲ 897.4%
-44.43M▼ 169.3%
19.48M▲ 143.8%
-16.71M▲ 0%
Free Cash Flow
-9.35M▲ 0%
-14.84M▼ 58.7%
-34.17M▼ 130.3%
-58.18M▼ 70.2%
-97.69M▼ 67.9%
-110.34M▼ 12.9%
-143.82M▼ 30.3%
-148.71M▲ 0%
FCF Margin %
--------
FCF Growth %
--58.67%-130.34%-70.24%-67.91%-12.95%-30.34%-24.59%
FCF per Share
-0.19-0.30-0.69-1.09-1.53-1.19-1.40-1.39
FCF Conversion (FCF/Net Income)
0.97x0.86x0.78x0.78x0.92x0.81x0.86x0.84x
Interest Paid
00000000
Taxes Paid
00000000

EWTX Key Ratios

Edgewise Therapeutics, Inc. (EWTX) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric202020212022202320242025TTM
Return on Equity (ROE)
--35.53%-21.78%-30.1%-34.4%-34.19%-32.55%
Return on Invested Capital (ROIC)
--23.09%-18.28%-30.24%-36.07%-32.35%-30%
Debt / Equity
--0.01x0.02x0.01x0.01x0.01x
Interest Coverage
---17.83x----
FCF Conversion
0.86x0.78x0.78x0.92x0.81x0.86x0.84x
Related:EWTX Dividend History·EWTX Revenue History·EWTX Price History·EWTX P/E History·EWTX Financial Ratios·EWTX Institutional Holders

EWTX SEC Filings & Documents

Edgewise Therapeutics, Inc. (EWTX) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 7, 2026·SEC

Material company update

Feb 26, 2026·SEC

Material company update

Nov 20, 2025·SEC

10-K Annual Reports

4
FY 2026

Feb 26, 2026·SEC

FY 2025

Mar 3, 2025·SEC

FY 2024

Feb 22, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 7, 2026·SEC

FY 2025

Nov 6, 2025·SEC

FY 2025

Aug 7, 2025·SEC

EWTX Frequently Asked Questions

Edgewise Therapeutics, Inc. (EWTX) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Edgewise Therapeutics, Inc. (EWTX) grew revenue by 0.0% over the past year. Growth has been modest.

Edgewise Therapeutics, Inc. (EWTX) reported a net loss of $176.0M for fiscal year 2025.

Dividend & Returns

Edgewise Therapeutics, Inc. (EWTX) has a return on equity (ROE) of -34.2%. Negative ROE indicates the company is unprofitable.

Edgewise Therapeutics, Inc. (EWTX) had negative free cash flow of $148.7M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in EWTX back in 2019?

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