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EWTXEdgewise Therapeutics, Inc.
$45.93$4.9B
Overview & Tools
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EWTX logo

Edgewise Therapeutics, Inc.

EWTX
NASDAQ · Metabolic & Cardiovascular Biotech
$45.93
At close - Nov 13, 4:00 PM EST - USD
Market Cap$4.94B
P/E5.5x
52W High$48.78
Volume1.15M
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q3

Pre-Revenue Biotech Burning Cash Against Thin Liquidity Runway

Edgewise Therapeutics remains pre-revenue across all ten reported quarters, with operating losses widening from roughly -$38.1M in 2024Q2 to -$61.9M in 2026Q2 as R&D climbed from $30.7M to $47.5M per quarter.

GrowthMixed
ProfitabilityNegative
ValuationAttractive
TechnicalsHealthy
Explore valuation models
MARKET ACTION

EWTX price & volume

Price trend, volume and key moving averages

Launch Terminal
Loading chart...
Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

8/12 Beats

EPS beat 8 of last 12 quarters

02

Valuation risk

-87% Peers

P/E is 87% below peer median

03

Market leadership

RS 86 · Leader

High momentum (Outperforming 86% of market)

04

Healthy Uptrend

Uptrend

Price > 50DMA > 200DMA

Next CatalystEstimated earnings · Feb 4

Market performance

Price History →

Trailing total returns as of 11/14/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
EWTX+93.39%
S&P 500 (^GSPC)+10.42%
1-Year Return
EWTX+124.93%
S&P 500 (^GSPC)+12.25%
3-Year Return
EWTX+649.27%
S&P 500 (^GSPC)+72.05%
5-Year Return
EWTX+133.98%
S&P 500 (^GSPC)+58.06%

Growth & profitability

Annual revenue & EPS trend
Revenue FY25
-
Net income FY25
-$168M-25.4% YoY
Free cash flow FY25
-$144M-30.3% YoY
Operating margin FY25
-
ROIC (FY25)-32.4%
Avg ROIC 5Y-28%
ROE (TTM)130.4%
Piotroski Score3 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate8/12 (67%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q4 2026Latest
Nov 4, 2026
$9.65+1914.0%
vs -$0.53
—
vs $119M
Q3 2026
Aug 6, 2026
-$0.53-13.3%
vs -$0.47
—
vs —
Q2 2026
May 7, 2026
-$0.46+8.0%
vs -$0.50
—
vs —
Q1 2026
Feb 26, 2026
-$0.47-9.3%
vs -$0.43
—
vs —
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

4 Stories
PRNewsWire·4d ago
Edgewise Therapeutics to Participate in Upcoming Investor Conferences

BOULDER, Colo., Nov. 9, 2026 /PRNewswire/ -- Edgewise Therapeutics, Inc. (Nasdaq: EWTX), a leading clinical-stage cardiovascular biopharmaceutical company, today announced that management will participate in the following investor conferences: Guggenheim 3rd Annual Healthcare Innovation Conference Fireside chat: Tuesday, November 10, 2026 at 8:00 am ET 2026 Truist Biopharma Symposium Fireside chat: Thursday, November 12, 2026 at 10:30 am ET The webcasts can be found on the Edgewise Events & Presentations page and will be accessible for replay, for a limited time, following the conference.

PRNewsWire·Nov 5, 2026
Edgewise Therapeutics Announces Productive End-of-Phase 2 Meeting with FDA for EDG-7500 in HCM; Phase 3 Protocol Features Tolerability-Based Dose Escalation Without Safety Echo Monitoring

– Following the End-of-Phase 2 meeting, Edgewise has submitted the STRATUS-HCM Phase 3 protocol with dose escalation guided by investigator assessment of tolerability – – STRATUS-HCM includes two independent placebo-controlled studies of symptomatic obstructive and nonobstructive HCM populations under a single master protocol, with peak VO ₂ as the primary endpoint – – STRATUS-HCM on track to start in the fourth quarter of 2026 – BOULDER, Colo., Nov. 5, 2026 /PRNewswire/ -- Edgewise Therapeutics, Inc. (Nasdaq: EWTX), a leading clinical-stage cardiovascular biopharmaceutical company, today announced favorable feedback from its End-of-Phase 2 meeting with the U.S. Food and Drug Administration (FDA) for EDG-7500 in symptomatic obstructive and nonobstructive hypertrophic cardiomyopathy (HCM).

PRNewsWire·Nov 4, 2026
Edgewise Therapeutics Reports Third Quarter 2026 Financial Results

–  Published the differentiated mechanism of action of EDG-7500 that targets the regulatory light chain – –  Phase 3 trial for EDG-7500 in obstructive and nonobstructive hypertrophic cardiomyopathy (HCM) on track to initiate by year-end 2026 – –  Dosed first patient in Phase 2 EQUINOX-HFpEF trial of EDG-15400 in heart failure with preserved ejection fraction (HFpEF) – BOULDER, Colo., Nov. 4, 2026 /PRNewswire/ -- Edgewise Therapeutics, Inc. (Nasdaq: EWTX), a leading clinical-stage cardiovascular biopharmaceutical company, today reported financial results for the third quarter of 2026 and recent business highlights.

PRNewsWire·Nov 2, 2026
Edgewise Therapeutics Reports Inducement Grants as permitted by the Nasdaq Listing Rules

BOULDER, Colo., Nov. 2, 2026 /PRNewswire/ -- Edgewise Therapeutics, Inc. ("Edgewise" or the "Company"), (Nasdaq: EWTX), a leading clinical-stage cardiovascular biopharmaceutical company, today announced that on October 30, 2026, Edgewise granted inducement stock options to purchase a total of 17,250 shares of Edgewise's common stock and awards of inducement restricted stock units (each, an "RSU award") covering a total of 8,626 shares of Edgewise's common stock to 2 new non-executive employees in connection with the commencement of their employment, pursuant to Edgewise's 2024 Inducement Equity Incentive Plan (the "Inducement Plan").

Filtered for Edgewise Therapeutics, Inc.More Headlines
04

Compare before deciding

Benchmark EWTX against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Edgewise Therapeutics, Inc. (EWTX)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
EWTX logoEWTXEdgewise Therapeutics, Inc.Current
$45.93$4.94B5.50——130.43%—
ACAD logoACADACADIA Pharmaceuticals Inc.
$18.75$3.21B9.0811.87%30.13%28.03%—
KYMR logoKYMRKymera Therapeutics, Inc.
$127.57$10.49B-36.54-16.72%-341.87%-22.39%—
CMPS logoCMPSCOMPASS Pathways plc
$9.01$1.22B-5.50——-212.85%—
IMVT logoIMVTImmunovant, Inc.
$34.18$7.05B-13.88—-7173.52%-63.01%—
ARQT logoARQTArcutis Biotherapeutics, Inc.
$28.26$3.53B129.2891.34%5.88%14.18%—

Compare EWTX vs Peers

Edgewise Therapeutics, Inc. (EWTX) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs ACAD

Most directly comparable listed peer for EWTX.

Scale Benchmark

vs ABBV

Larger-name benchmark to compare EWTX against a more recognizable public peer.

Peer Set

Compare Top 5

vs ACAD, KYMR, CMPS, IMVT

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

EWTX SEC Filings & Documents

Edgewise Therapeutics, Inc. (EWTX) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Nov 4, 2026·SEC

Material company update

Aug 6, 2026·SEC

Material company update

Jul 13, 2026·SEC

10-K Annual Reports

3
FY 2026

Feb 26, 2026·SEC

FY 2025

Mar 3, 2025·SEC

FY 2024

Feb 22, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

Nov 4, 2026·SEC

FY 2026

Aug 6, 2026·SEC

FY 2026

May 7, 2026·SEC

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EWTX Frequently Asked Questions

Edgewise Therapeutics, Inc. (EWTX) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
Is EWTX profitable?

Yes. Edgewise Therapeutics, Inc. (EWTX) earned $1.01B in net income over the trailing twelve months.

Dividend & Returns
What is EWTX's return on equity?

Edgewise Therapeutics, Inc. (EWTX) had a return on equity (ROE) of 130.4% over the trailing twelve months. That is well above the market's typical 10-15%.

What is Edgewise Therapeutics, Inc.'s free cash flow?

Edgewise Therapeutics, Inc. (EWTX) had negative free cash flow of $202.0M over the trailing twelve months.

What if you invested $1,000 in EWTX back in 2019?

Total return calculator · dividends reinvested · 7+ years of data

See returns →