Biotechnology
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FBIO vs AVXL
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
FBIO vs AVXL — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||
|---|---|---|
| Industry | Biotechnology | Biotechnology |
| Market Cap | $67M | $289M |
| Revenue (TTM) | $62M | $0.00 |
| Net Income (TTM) | $4M | $-40M |
| Gross Margin | 65.8% | — |
| Operating Margin | -149.2% | — |
| Forward P/E | 240.0x | — |
| Total Debt | $76M | $0.00 |
| Cash & Equiv. | $57M | $103M |
FBIO vs AVXL — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Fortress Biotech, I… (FBIO) | 100 | 5.5 | -94.5% |
| Anavex Life Science… (AVXL) | 100 | 75.9 | -24.1% |
Price return only. Dividends and distributions are not included.
Quick Verdict: FBIO vs AVXL
Each card shows where this stock fits in a portfolio — not just who wins on paper.
FBIO carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- Dividend streak 0 yrs, beta 0.97, yield 1.4%
- Rev growth -31.8%, EPS growth 68.2%, 3Y rev CAGR -5.7%
- Lower volatility, beta 0.97, current ratio 1.27x
AVXL is the clearest fit if your priority is long-term compounding.
- -25.7% 10Y total return vs FBIO's -94.8%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | -31.8% revenue growth vs AVXL's -34.9% | |
| Quality / Margins | 6.4% margin vs AVXL's 4.5% | |
| Stability / Safety | Beta 0.97 vs AVXL's 1.51 | |
| Dividends | 1.4% yield; the other pay no meaningful dividend | |
| Momentum (1Y) | +39.5% vs AVXL's -63.2% | |
| Efficiency (ROA) | 2.2% ROA vs AVXL's -30.0% |
FBIO vs AVXL — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
FBIO vs AVXL — Financial Metrics
Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.
Income & Cash Flow (Last 12 Months)
FBIO leads this category, winning 1 of 1 comparable metric.
Income & Cash Flow (Last 12 Months)
FBIO and AVXL operate at a comparable scale, with $62M and $0 in trailing revenue.
| Metric | ||
|---|---|---|
| RevenueTrailing 12 months | $62M | $0 |
| EBITDAEarnings before interest/tax | -$88M | -$30M |
| Net IncomeAfter-tax profit | $4M | -$40M |
| Free Cash FlowCash after capex | -$66M | -$34M |
| Gross MarginGross profit ÷ Revenue | +65.8% | — |
| Operating MarginEBIT ÷ Revenue | -149.2% | — |
| Net MarginNet income ÷ Revenue | +6.4% | — |
| FCF MarginFCF ÷ Revenue | -106.2% | — |
| Rev. Growth (YoY)Latest quarter vs prior year | +20.5% | — |
| EPS Growth (YoY)Latest quarter vs prior year | +114.5% | +54.4% |
Valuation Metrics
AVXL leads this category, winning 1 of 1 comparable metric.
Valuation Metrics
| Metric | ||
|---|---|---|
| Market CapShares × price | $67M | $289M |
| Enterprise ValueMkt cap + debt − cash | $86M | $187M |
| Trailing P/EPrice ÷ TTM EPS | -0.89x | -5.78x |
| Forward P/EPrice ÷ next-FY EPS est. | 240.00x | — |
| PEG RatioP/E ÷ EPS growth rate | — | — |
| EV / EBITDAEnterprise value multiple | — | — |
| Price / SalesMarket cap ÷ Revenue | 1.16x | — |
| Price / BookPrice ÷ Book value/share | — | 2.81x |
| Price / FCFMarket cap ÷ FCF | — | — |
Profitability & Efficiency
AVXL leads this category, winning 4 of 6 comparable metrics.
Profitability & Efficiency
FBIO delivers a 6.1% return on equity — every $100 of shareholder capital generates $6 in annual profit, vs $-32 for AVXL. On the Piotroski fundamental quality scale (0–9), AVXL scores 2/9 vs FBIO's 1/9, reflecting mixed financial health.
| Metric | ||
|---|---|---|
| ROE (TTM)Return on equity | +6.1% | -31.5% |
| ROA (TTM)Return on assets | +2.2% | -30.0% |
| ROICReturn on invested capital | -6.3% | — |
| ROCEReturn on capital employed | -142.0% | -47.8% |
| Piotroski ScoreFundamental quality 0–9 | 1 | 2 |
| Debt / EquityFinancial leverage | — | — |
| Net DebtTotal debt minus cash | $19M | -$103M |
| Cash & Equiv.Liquid assets | $57M | $103M |
| Total DebtShort + long-term debt | $76M | $0 |
| Interest CoverageEBIT ÷ Interest expense | -4.25x | — |
Total Returns (Dividends Reinvested)
AVXL leads this category, winning 5 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in AVXL five years ago would be worth $2,759 today (with dividends reinvested), compared to $406 for FBIO. Over the past 12 months, FBIO leads with a +39.5% total return vs AVXL's -63.2%. The 3-year compound annual growth rate (CAGR) favors AVXL at -28.1% vs FBIO's -40.0% — a key indicator of consistent wealth creation.
| Metric | ||
|---|---|---|
| YTD ReturnYear-to-date | -40.4% | -15.2% |
| 1-Year ReturnPast 12 months | +39.5% | -63.2% |
| 3-Year ReturnCumulative with dividends | -78.4% | -62.9% |
| 5-Year ReturnCumulative with dividends | -95.9% | -72.4% |
| 10-Year ReturnCumulative with dividends | -94.8% | -25.7% |
| CAGR (3Y)Annualised 3-year return | -40.0% | -28.1% |
Risk & Volatility
FBIO leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
FBIO is the less volatile stock with a 0.97 beta — it tends to amplify market swings less than AVXL's 1.51 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. FBIO currently trades 53.0% from its 52-week high vs AVXL's 22.3% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.97x | 1.51x |
| 52-Week HighHighest price in past year | $4.53 | $13.99 |
| 52-Week LowLowest price in past year | $1.60 | $2.61 |
| % of 52W HighCurrent price vs 52-week peak | +53.0% | +22.3% |
| RSI (14)Momentum oscillator 0–100 | 54.7 | 47.0 |
| Avg Volume (50D)Average daily shares traded | 407K | 1.4M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Wall Street rates FBIO as "Buy" and AVXL as "Buy". FBIO is the only dividend payer here at 1.39% yield — a key consideration for income-focused portfolios.
| Metric | ||
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy |
| Price TargetConsensus 12-month target | — | $11.00 |
| # AnalystsCovering analysts | 6 | 13 |
| Dividend YieldAnnual dividend ÷ price | +1.4% | — |
| Dividend StreakConsecutive years of raises | 0 | — |
| Dividend / ShareAnnual DPS | $0.03 | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% |
AVXL leads in 3 of 6 categories (Valuation Metrics, Profitability & Efficiency). FBIO leads in 2 (Income & Cash Flow, Risk & Volatility).
FBIO vs AVXL: Frequently Asked Questions
8 questions · data-driven answers · updated daily
01Is FBIO or AVXL a better buy right now?
Analysts rate Fortress Biotech, Inc.
(FBIO) a "Buy" — based on 6 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — FBIO or AVXL?
Over the past 5 years, Anavex Life Sciences Corp.
(AVXL) delivered a total return of -72. 4%, compared to -95. 9% for Fortress Biotech, Inc. (FBIO). Over 10 years, the gap is even starker: AVXL returned -25. 7% versus FBIO's -94. 8%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — FBIO or AVXL?
By beta (market sensitivity over 5 years), Fortress Biotech, Inc.
(FBIO) is the lower-risk stock at 0. 97β versus Anavex Life Sciences Corp. 's 1. 51β — meaning AVXL is approximately 55% more volatile than FBIO relative to the S&P 500.
04Which is growing faster — FBIO or AVXL?
On earnings-per-share growth, the picture is similar: Fortress Biotech, Inc.
grew EPS 68. 2% year-over-year, compared to -3. 8% for Anavex Life Sciences Corp.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — FBIO or AVXL?
Anavex Life Sciences Corp.
(AVXL) is the more profitable company, earning 0. 0% net margin versus -79. 8% for Fortress Biotech, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: AVXL leads at 0. 0% versus -191. 4% for FBIO. At the gross margin level — before operating expenses — FBIO leads at 63. 8%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — FBIO or AVXL?
In this comparison, FBIO (1.
4% yield) pays a dividend. AVXL does not pay a meaningful dividend and should not be held primarily for income.
07Is FBIO or AVXL better for a retirement portfolio?
For long-horizon retirement investors, Fortress Biotech, Inc.
(FBIO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 97), 1. 4% yield). Anavex Life Sciences Corp. (AVXL) carries a higher beta of 1. 51 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (FBIO: -94. 8%, AVXL: -25. 7%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between FBIO and AVXL?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
FBIO pays a dividend while AVXL does not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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