Biotechnology
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5 / 10Stock Comparison
FBRX vs ABBV vs PFE vs REGN vs IQV
Revenue, margins, valuation, and 5-year total return — side by side.
Drug Manufacturers - General
Drug Manufacturers - General
Biotechnology
Medical - Diagnostics & Research
FBRX vs ABBV vs PFE vs REGN vs IQV — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Drug Manufacturers - General | Drug Manufacturers - General | Biotechnology | Medical - Diagnostics & Research |
| Market Cap | $70M | $356.49B | $146.02B | $74.28B | $30.33B |
| Revenue (TTM) | $0.00 | $61.16B | $63.31B | $14.92B | $16.63B |
| Net Income (TTM) | $-52M | $4.23B | $7.49B | $4.42B | $1.39B |
| Gross Margin | — | 70.2% | 69.3% | 84.5% | 26.1% |
| Operating Margin | — | 26.7% | 23.4% | 24.3% | 13.9% |
| Forward P/E | — | 14.2x | 8.7x | 15.5x | 14.0x |
| Total Debt | $0.00 | $69.07B | $67.42B | $2.71B | $16.17B |
| Cash & Equiv. | $22M | $5.23B | $1.14B | $3.12B | $1.98B |
FBRX vs ABBV vs PFE vs REGN vs IQV — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Forte Biosciences, … (FBRX) | 100 | 5.3 | -94.7% |
| AbbVie Inc. (ABBV) | 100 | 217.5 | +117.5% |
| Pfizer Inc. (PFE) | 100 | 70.9 | -29.1% |
| Regeneron Pharmaceu… (REGN) | 100 | 116.7 | +16.7% |
| IQVIA Holdings Inc. (IQV) | 100 | 119.5 | +19.5% |
Price return only. Dividends and distributions are not included.
Quick Verdict: FBRX vs ABBV vs PFE vs REGN vs IQV
Each card shows where this stock fits in a portfolio — not just who wins on paper.
FBRX ranks third and is worth considering specifically for momentum.
- +285.6% vs ABBV's +12.2%
ABBV has the current edge in this matchup, primarily because of its strength in growth exposure and long-term compounding.
- Rev growth 8.6%, EPS growth -0.8%, 3Y rev CAGR 1.8%
- 293.8% 10Y total return vs REGN's 91.6%
- 8.6% revenue growth vs FBRX's -51.3%
- Beta 0.28 vs FBRX's 1.47
PFE is the clearest fit if your priority is income & stability and defensive.
- Dividend streak 15 yrs, beta 0.49, yield 6.7%
- Beta 0.49, yield 6.7%, current ratio 1.16x
- 6.7% yield, 15-year raise streak, vs ABBV's 3.3%, (2 stocks pay no dividend)
REGN is the #2 pick in this set and the best alternative if sleep-well-at-night is your priority.
- Lower volatility, beta 0.77, Low D/E 8.7%, current ratio 4.13x
- 29.6% margin vs FBRX's 2.1%
- 11.1% ROA vs FBRX's -53.3%, ROIC 8.9% vs -102.5%
IQV is the clearest fit if your priority is valuation efficiency.
- PEG 0.34 vs REGN's 2.44
- Lower P/E (14.0x vs 15.5x), PEG 0.34 vs 2.44
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 8.6% revenue growth vs FBRX's -51.3% | |
| Value | Lower P/E (14.0x vs 15.5x), PEG 0.34 vs 2.44 | |
| Quality / Margins | 29.6% margin vs FBRX's 2.1% | |
| Stability / Safety | Beta 0.28 vs FBRX's 1.47 | |
| Dividends | 6.7% yield, 15-year raise streak, vs ABBV's 3.3%, (2 stocks pay no dividend) | |
| Momentum (1Y) | +285.6% vs ABBV's +12.2% | |
| Efficiency (ROA) | 11.1% ROA vs FBRX's -53.3%, ROIC 8.9% vs -102.5% |
FBRX vs ABBV vs PFE vs REGN vs IQV — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
FBRX vs ABBV vs PFE vs REGN vs IQV — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
IQV leads in 1 of 6 categories
REGN leads 1 • ABBV leads 1 • PFE leads 1 • FBRX leads 0 • 2 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
Evenly matched — ABBV and REGN each lead in 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
PFE and FBRX operate at a comparable scale, with $63.3B and $0 in trailing revenue. REGN is the more profitable business, keeping 29.6% of every revenue dollar as net income compared to ABBV's 6.9%. On growth, REGN holds the edge at +19.0% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $61.2B | $63.3B | $14.9B | $16.6B |
| EBITDAEarnings before interest/tax | -$53M | $24.5B | $21.0B | $4.2B | $3.5B |
| Net IncomeAfter-tax profit | -$52M | $4.2B | $7.5B | $4.4B | $1.4B |
| Free Cash FlowCash after capex | -$45M | $18.7B | $9.5B | $4.2B | $2.7B |
| Gross MarginGross profit ÷ Revenue | — | +70.2% | +69.3% | +84.5% | +26.1% |
| Operating MarginEBIT ÷ Revenue | — | +26.7% | +23.4% | +24.3% | +13.9% |
| Net MarginNet income ÷ Revenue | — | +6.9% | +11.8% | +29.6% | +8.3% |
| FCF MarginFCF ÷ Revenue | — | +30.6% | +15.0% | +27.9% | +16.1% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | +10.0% | +5.4% | +19.0% | +8.4% |
| EPS Growth (YoY)Latest quarter vs prior year | +78.2% | +57.4% | -9.5% | -7.2% | +15.0% |
Valuation Metrics
IQV leads this category, winning 3 of 7 comparable metrics.
Valuation Metrics
At 17.2x trailing earnings, REGN trades at a 80% valuation discount to ABBV's 85.0x P/E. Adjusting for growth (PEG ratio), IQV offers better value at 0.56x vs REGN's 2.72x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $70M | $356.5B | $146.0B | $74.3B | $30.3B |
| Enterprise ValueMkt cap + debt − cash | $48M | $420.3B | $212.3B | $73.9B | $44.5B |
| Trailing P/EPrice ÷ TTM EPS | -1.97x | 85.04x | 18.88x | 17.23x | 22.79x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 14.17x | 8.66x | 15.46x | 13.96x |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | 2.72x | 0.56x |
| EV / EBITDAEnterprise value multiple | — | 14.89x | 10.44x | 17.92x | 12.98x |
| Price / SalesMarket cap ÷ Revenue | — | 5.83x | 2.33x | 5.18x | 1.86x |
| Price / BookPrice ÷ Book value/share | 1.33x | — | 1.68x | 2.48x | 4.68x |
| Price / FCFMarket cap ÷ FCF | — | 20.01x | 16.09x | 18.20x | 14.79x |
Profitability & Efficiency
REGN leads this category, winning 4 of 9 comparable metrics.
Profitability & Efficiency
ABBV delivers a 62.1% return on equity — every $100 of shareholder capital generates $62 in annual profit, vs $-62 for FBRX. REGN carries lower financial leverage with a 0.09x debt-to-equity ratio, signaling a more conservative balance sheet compared to IQV's 2.44x. On the Piotroski fundamental quality scale (0–9), PFE scores 7/9 vs FBRX's 2/9, reflecting strong financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -61.5% | +62.1% | +8.3% | +14.3% | +22.1% |
| ROA (TTM)Return on assets | -53.3% | +3.1% | +3.6% | +11.1% | +4.7% |
| ROICReturn on invested capital | -102.5% | +23.9% | +7.5% | +8.9% | +8.7% |
| ROCEReturn on capital employed | -83.4% | +21.5% | +9.0% | +10.2% | +11.0% |
| Piotroski ScoreFundamental quality 0–9 | 2 | 6 | 7 | 5 | 4 |
| Debt / EquityFinancial leverage | — | — | 0.78x | 0.09x | 2.44x |
| Net DebtTotal debt minus cash | -$22M | $63.8B | $66.3B | -$412M | $14.2B |
| Cash & Equiv.Liquid assets | $22M | $5.2B | $1.1B | $3.1B | $2.0B |
| Total DebtShort + long-term debt | $0 | $69.1B | $67.4B | $2.7B | $16.2B |
| Interest CoverageEBIT ÷ Interest expense | — | 3.28x | 4.02x | 108.44x | 3.10x |
Total Returns (Dividends Reinvested)
ABBV leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ABBV five years ago would be worth $19,956 today (with dividends reinvested), compared to $303 for FBRX. Over the past 12 months, FBRX leads with a +285.6% total return vs ABBV's +12.2%. The 3-year compound annual growth rate (CAGR) favors ABBV at 14.4% vs PFE's -6.9% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | +1.7% | -10.6% | +5.4% | -7.8% | -20.7% |
| 1-Year ReturnPast 12 months | +285.6% | +12.2% | +21.1% | +31.2% | +16.6% |
| 3-Year ReturnCumulative with dividends | -9.4% | +49.7% | -19.4% | -4.4% | -5.9% |
| 5-Year ReturnCumulative with dividends | -97.0% | +99.6% | -14.8% | +43.2% | -22.8% |
| 10-Year ReturnCumulative with dividends | -99.5% | +293.8% | +28.5% | +91.6% | +166.6% |
| CAGR (3Y)Annualised 3-year return | -3.2% | +14.4% | -6.9% | -1.5% | -2.0% |
Risk & Volatility
Evenly matched — ABBV and PFE each lead in 1 of 2 comparable metrics.
Risk & Volatility
ABBV is the less volatile stock with a 0.28 beta — it tends to amplify market swings less than FBRX's 1.47 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. PFE currently trades 89.3% from its 52-week high vs FBRX's 67.1% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.47x | 0.28x | 0.49x | 0.77x | 1.32x |
| 52-Week HighHighest price in past year | $35.80 | $244.81 | $28.75 | $821.11 | $247.05 |
| 52-Week LowLowest price in past year | $6.19 | $176.57 | $21.97 | $476.49 | $134.65 |
| % of 52W HighCurrent price vs 52-week peak | +67.1% | +82.3% | +89.3% | +87.1% | +72.3% |
| RSI (14)Momentum oscillator 0–100 | 43.1 | 43.9 | 43.9 | 41.7 | 60.3 |
| Avg Volume (50D)Average daily shares traded | 274K | 5.8M | 33.3M | 626K | 1.5M |
Analyst Outlook
PFE leads this category, winning 2 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: FBRX as "Buy", ABBV as "Buy", PFE as "Hold", REGN as "Buy", IQV as "Buy". Consensus price targets imply 170.6% upside for FBRX (target: $65) vs 6.7% for PFE (target: $27). For income investors, PFE offers the higher dividend yield at 6.69% vs REGN's 0.48%.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Hold | Buy | Buy |
| Price TargetConsensus 12-month target | $65.00 | $256.69 | $27.40 | $865.68 | $223.75 |
| # AnalystsCovering analysts | 6 | 41 | 39 | 48 | 44 |
| Dividend YieldAnnual dividend ÷ price | — | +3.3% | +6.7% | +0.5% | — |
| Dividend StreakConsecutive years of raises | — | 13 | 15 | 1 | 2 |
| Dividend / ShareAnnual DPS | — | $6.57 | $1.72 | $3.41 | — |
| Buyback YieldShare repurchases ÷ mkt cap | +0.0% | +0.3% | 0.0% | +5.3% | +4.1% |
IQV leads in 1 of 6 categories (Valuation Metrics). REGN leads in 1 (Profitability & Efficiency). 2 tied.
FBRX vs ABBV vs PFE vs REGN vs IQV: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is FBRX or ABBV or PFE or REGN or IQV a better buy right now?
For growth investors, AbbVie Inc.
(ABBV) is the stronger pick with 8. 6% revenue growth year-over-year, versus -1. 6% for Pfizer Inc. (PFE). Regeneron Pharmaceuticals, Inc. (REGN) offers the better valuation at 17. 2x trailing P/E (15. 5x forward), making it the more compelling value choice. Analysts rate Forte Biosciences, Inc. (FBRX) a "Buy" — based on 6 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — FBRX or ABBV or PFE or REGN or IQV?
On trailing P/E, Regeneron Pharmaceuticals, Inc.
(REGN) is the cheapest at 17. 2x versus AbbVie Inc. at 85. 0x. On forward P/E, Pfizer Inc. is actually cheaper at 8. 7x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: IQVIA Holdings Inc. wins at 0. 34x versus Regeneron Pharmaceuticals, Inc. 's 2. 44x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.
03Which is the better long-term investment — FBRX or ABBV or PFE or REGN or IQV?
Over the past 5 years, AbbVie Inc.
(ABBV) delivered a total return of +99. 6%, compared to -97. 0% for Forte Biosciences, Inc. (FBRX). Over 10 years, the gap is even starker: ABBV returned +293. 8% versus FBRX's -99. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — FBRX or ABBV or PFE or REGN or IQV?
By beta (market sensitivity over 5 years), AbbVie Inc.
(ABBV) is the lower-risk stock at 0. 28β versus Forte Biosciences, Inc. 's 1. 47β — meaning FBRX is approximately 433% more volatile than ABBV relative to the S&P 500. On balance sheet safety, Regeneron Pharmaceuticals, Inc. (REGN) carries a lower debt/equity ratio of 9% versus 2% for IQVIA Holdings Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — FBRX or ABBV or PFE or REGN or IQV?
By revenue growth (latest reported year), AbbVie Inc.
(ABBV) is pulling ahead at 8. 6% versus -1. 6% for Pfizer Inc. (PFE). On earnings-per-share growth, the picture is similar: Forte Biosciences, Inc. grew EPS 51. 2% year-over-year, compared to -3. 5% for Pfizer Inc.. Over a 3-year CAGR, REGN leads at 5. 6% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — FBRX or ABBV or PFE or REGN or IQV?
Regeneron Pharmaceuticals, Inc.
(REGN) is the more profitable company, earning 31. 4% net margin versus 0. 0% for Forte Biosciences, Inc. — meaning it keeps 31. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ABBV leads at 32. 8% versus 0. 0% for FBRX. At the gross margin level — before operating expenses — REGN leads at 85. 4%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is FBRX or ABBV or PFE or REGN or IQV more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, IQVIA Holdings Inc. (IQV) is the more undervalued stock at a PEG of 0. 34x versus Regeneron Pharmaceuticals, Inc. 's 2. 44x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Pfizer Inc. (PFE) trades at 8. 7x forward P/E versus 15. 5x for Regeneron Pharmaceuticals, Inc. — 6. 8x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for FBRX: 170. 6% to $65. 00.
08Which pays a better dividend — FBRX or ABBV or PFE or REGN or IQV?
In this comparison, PFE (6.
7% yield), ABBV (3. 3% yield), REGN (0. 5% yield) pay a dividend. FBRX, IQV do not pay a meaningful dividend and should not be held primarily for income.
09Is FBRX or ABBV or PFE or REGN or IQV better for a retirement portfolio?
For long-horizon retirement investors, AbbVie Inc.
(ABBV) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 28), 3. 3% yield, +293. 8% 10Y return). Both have compounded well over 10 years (ABBV: +293. 8%, FBRX: -99. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between FBRX and ABBV and PFE and REGN and IQV?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: FBRX is a small-cap quality compounder stock; ABBV is a large-cap income-oriented stock; PFE is a mid-cap income-oriented stock; REGN is a mid-cap deep-value stock; IQV is a mid-cap quality compounder stock. ABBV, PFE pay a dividend while FBRX, REGN, IQV do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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