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Stock Comparison

FDMT vs QURE vs CRSP vs RCKT vs EDIT

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
FDMT
4D Molecular Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$519M
5Y Perf.-75.5%
QURE
uniQure N.V.

Biotechnology

HealthcareNASDAQ • NL
Market Cap$1.49B
5Y Perf.-23.4%
CRSP
CRISPR Therapeutics AG

Biotechnology

HealthcareNASDAQ • CH
Market Cap$5.06B
5Y Perf.-64.2%
RCKT
Rocket Pharmaceuticals, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$398M
5Y Perf.-93.4%
EDIT
Editas Medicine, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$297M
5Y Perf.-95.6%

FDMT vs QURE vs CRSP vs RCKT vs EDIT — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
FDMT logoFDMT
QURE logoQURE
CRSP logoCRSP
RCKT logoRCKT
EDIT logoEDIT
IndustryBiotechnologyBiotechnologyBiotechnologyBiotechnologyBiotechnology
Market Cap$519M$1.49B$5.06B$398M$297M
Revenue (TTM)$85M$18M$4M$0.00$0.00
Net Income (TTM)$-161M$-209M$-569M$-223M$-160M
Gross Margin-14.1%74.1%-41.7%
Operating Margin-210.7%-10.8%-134.1%
Total Debt$21M$537M$395M$25M$18M
Cash & Equiv.$60M$80M$355M$78M$147M

FDMT vs QURE vs CRSP vs RCKT vs EDITLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

FDMT
QURE
CRSP
RCKT
EDIT
StockDec 20May 26Return
4D Molecular Therap… (FDMT)10024.5-75.5%
uniQure N.V. (QURE)10076.6-23.4%
CRISPR Therapeutics… (CRSP)10035.8-64.2%
Rocket Pharmaceutic… (RCKT)1006.6-93.4%
Editas Medicine, In… (EDIT)1004.4-95.6%

Price return only. Dividends and distributions are not included.

Quick Verdict: FDMT vs QURE vs CRSP vs RCKT vs EDIT

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: FDMT leads in 3 of 6 categories (5-stock set), making it the strongest pick for growth and revenue expansion and profitability and margin quality. uniQure N.V. is the stronger pick specifically for capital preservation and lower volatility. CRSP also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
FDMT
4D Molecular Therapeutics, Inc.
The Growth Play

FDMT carries the broadest edge in this set and is the clearest fit for growth exposure.

  • Rev growth 2.3K%, EPS growth 18.8%, 3Y rev CAGR 200.9%
  • 2.3K% revenue growth vs EDIT's -100.0%
  • -188.9% margin vs CRSP's -138.6%
  • +218.3% vs RCKT's -45.2%
Best for: growth exposure
QURE
uniQure N.V.
The Income Pick

QURE is the #2 pick in this set and the best alternative if income & stability and sleep-well-at-night is your priority.

  • beta 1.26
  • Lower volatility, beta 1.26, current ratio 10.43x
  • Beta 1.26, current ratio 10.43x
  • Beta 1.26 vs EDIT's 2.52
Best for: income & stability and sleep-well-at-night
CRSP
CRISPR Therapeutics AG
The Long-Run Compounder

CRSP ranks third and is worth considering specifically for long-term compounding.

  • 272.0% 10Y total return vs QURE's 86.3%
  • -24.5% ROA vs EDIT's -74.2%
Best for: long-term compounding
RCKT
Rocket Pharmaceuticals, Inc.
The Healthcare Pick

RCKT lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
EDIT
Editas Medicine, Inc.
The Healthcare Pick

Among these 5 stocks, EDIT doesn't own a clear edge in any measured category.

Best for: healthcare exposure
See the full category breakdown
CategoryWinnerWhy
GrowthFDMT logoFDMT2.3K% revenue growth vs EDIT's -100.0%
Quality / MarginsFDMT logoFDMT-188.9% margin vs CRSP's -138.6%
Stability / SafetyQURE logoQUREBeta 1.26 vs EDIT's 2.52
DividendsTieNone of these 5 stocks pay a meaningful dividend
Momentum (1Y)FDMT logoFDMT+218.3% vs RCKT's -45.2%
Efficiency (ROA)CRSP logoCRSP-24.5% ROA vs EDIT's -74.2%

FDMT vs QURE vs CRSP vs RCKT vs EDIT — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

FDMT4D Molecular Therapeutics, Inc.
FY 2025
Collaboration And License Revenue
100.0%$85M
QUREuniQure N.V.
FY 2025
License revenues
99.0%$16M
Collaboration revenues
1.0%$164,000
CRSPCRISPR Therapeutics AG
FY 2025
Grant
100.0%$4M
RCKTRocket Pharmaceuticals, Inc.

Segment breakdown not available.

EDITEditas Medicine, Inc.
FY 2025
Reportable Segment
100.0%$41M

FDMT vs QURE vs CRSP vs RCKT vs EDIT — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLFDMTLAGGINGEDIT

Income & Cash Flow (Last 12 Months)

FDMT leads this category, winning 3 of 6 comparable metrics.

FDMT and EDIT operate at a comparable scale, with $85M and $0 in trailing revenue. Profitability is closely matched — net margins range from -188.9% (FDMT) to -138.6% (CRSP). On growth, QURE holds the edge at +127.3% YoY revenue growth, suggesting stronger near-term business momentum.

MetricFDMT logoFDMT4D Molecular Ther…QURE logoQUREuniQure N.V.CRSP logoCRSPCRISPR Therapeuti…RCKT logoRCKTRocket Pharmaceut…EDIT logoEDITEditas Medicine, …
RevenueTrailing 12 months$85M$18M$4M$0$0
EBITDAEarnings before interest/tax-$181M-$183M-$535M-$232M$0
Net IncomeAfter-tax profit-$161M-$209M-$569M-$223M-$160M
Free Cash FlowCash after capex-$130M-$172M-$401M-$190M-$166M
Gross MarginGross profit ÷ Revenue-14.1%+74.1%-41.7%
Operating MarginEBIT ÷ Revenue-2.1%-10.8%-134.1%
Net MarginNet income ÷ Revenue-188.9%-11.5%-138.6%
FCF MarginFCF ÷ Revenue-152.7%-9.5%-97.8%
Rev. Growth (YoY)Latest quarter vs prior year-100.0%+127.3%+68.6%-151.6%
EPS Growth (YoY)Latest quarter vs prior year-17.4%-3.7%+19.0%+38.7%+105.5%
FDMT leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

FDMT leads this category, winning 2 of 3 comparable metrics.
MetricFDMT logoFDMT4D Molecular Ther…QURE logoQUREuniQure N.V.CRSP logoCRSPCRISPR Therapeuti…RCKT logoRCKTRocket Pharmaceut…EDIT logoEDITEditas Medicine, …
Market CapShares × price$519M$1.5B$5.1B$398M$297M
Enterprise ValueMkt cap + debt − cash$480M$1.9B$5.1B$345M$168M
Trailing P/EPrice ÷ TTM EPS-4.10x-6.98x-8.10x-1.83x-1.68x
Forward P/EPrice ÷ next-FY EPS est.
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple
Price / SalesMarket cap ÷ Revenue6.09x92.42x1440.41x
Price / BookPrice ÷ Book value/share1.14x6.98x2.45x1.47x9.85x
Price / FCFMarket cap ÷ FCF
FDMT leads this category, winning 2 of 3 comparable metrics.

Profitability & Efficiency

CRSP leads this category, winning 4 of 8 comparable metrics.

CRSP delivers a -30.9% return on equity — every $100 of shareholder capital generates $-31 in annual profit, vs $-5 for EDIT. FDMT carries lower financial leverage with a 0.04x debt-to-equity ratio, signaling a more conservative balance sheet compared to QURE's 2.70x. On the Piotroski fundamental quality scale (0–9), FDMT scores 4/9 vs EDIT's 1/9, reflecting mixed financial health.

MetricFDMT logoFDMT4D Molecular Ther…QURE logoQUREuniQure N.V.CRSP logoCRSPCRISPR Therapeuti…RCKT logoRCKTRocket Pharmaceut…EDIT logoEDITEditas Medicine, …
ROE (TTM)Return on equity-36.8%-145.8%-30.9%-80.5%-5.2%
ROA (TTM)Return on assets-32.5%-27.2%-24.5%-67.5%-74.2%
ROICReturn on invested capital-28.1%-50.7%-22.3%-63.2%
ROCEReturn on capital employed-30.3%-29.4%-26.6%-58.9%
Piotroski ScoreFundamental quality 0–944111
Debt / EquityFinancial leverage0.04x2.70x0.21x0.09x0.66x
Net DebtTotal debt minus cash-$39M$456M$40M-$53M-$129M
Cash & Equiv.Liquid assets$60M$80M$355M$78M$147M
Total DebtShort + long-term debt$21M$537M$395M$25M$18M
Interest CoverageEBIT ÷ Interest expense-2.92x
CRSP leads this category, winning 4 of 8 comparable metrics.

Total Returns (Dividends Reinvested)

QURE leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in QURE five years ago would be worth $7,419 today (with dividends reinvested), compared to $838 for RCKT. Over the past 12 months, FDMT leads with a +218.3% total return vs RCKT's -45.2%. The 3-year compound annual growth rate (CAGR) favors QURE at 3.8% vs RCKT's -44.4% — a key indicator of consistent wealth creation.

MetricFDMT logoFDMT4D Molecular Ther…QURE logoQUREuniQure N.V.CRSP logoCRSPCRISPR Therapeuti…RCKT logoRCKTRocket Pharmaceut…EDIT logoEDITEditas Medicine, …
YTD ReturnYear-to-date+35.7%+3.2%-2.5%+6.1%+47.8%
1-Year ReturnPast 12 months+218.3%+140.1%+53.1%-45.2%+127.8%
3-Year ReturnCumulative with dividends-39.9%+11.7%-6.3%-82.8%-68.5%
5-Year ReturnCumulative with dividends-69.7%-25.8%-51.3%-91.6%-91.1%
10-Year ReturnCumulative with dividends-75.5%+86.3%+272.0%-91.3%-90.0%
CAGR (3Y)Annualised 3-year return-15.6%+3.8%-2.2%-44.4%-32.0%
QURE leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

Evenly matched — FDMT and RCKT each lead in 1 of 2 comparable metrics.

QURE is the less volatile stock with a 1.26 beta — it tends to amplify market swings less than EDIT's 2.52 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. FDMT currently trades 80.5% from its 52-week high vs QURE's 33.8% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricFDMT logoFDMT4D Molecular Ther…QURE logoQUREuniQure N.V.CRSP logoCRSPCRISPR Therapeuti…RCKT logoRCKTRocket Pharmaceut…EDIT logoEDITEditas Medicine, …
Beta (5Y)Sensitivity to S&P 5001.35x1.26x1.87x1.21x2.45x
52-Week HighHighest price in past year$12.34$71.50$78.48$7.39$4.54
52-Week LowLowest price in past year$3.00$8.73$33.50$2.19$1.29
% of 52W HighCurrent price vs 52-week peak+80.5%+33.8%+66.8%+49.7%+66.7%
RSI (14)Momentum oscillator 0–10061.068.055.554.457.5
Avg Volume (50D)Average daily shares traded737K3.3M2.0M3.5M1.6M
Evenly matched — FDMT and RCKT each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: FDMT as "Buy", QURE as "Buy", CRSP as "Buy", RCKT as "Buy", EDIT as "Buy". Consensus price targets imply 232.3% upside for FDMT (target: $33) vs 20.2% for CRSP (target: $63).

MetricFDMT logoFDMT4D Molecular Ther…QURE logoQUREuniQure N.V.CRSP logoCRSPCRISPR Therapeuti…RCKT logoRCKTRocket Pharmaceut…EDIT logoEDITEditas Medicine, …
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuyBuy
Price TargetConsensus 12-month target$33.00$36.11$63.00$5.00$5.00
# AnalystsCovering analysts1436381925
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

FDMT leads in 2 of 6 categories (Income & Cash Flow, Valuation Metrics). CRSP leads in 1 (Profitability & Efficiency). 1 tied.

Best Overall4D Molecular Therapeutics, … (FDMT)Leads 2 of 6 categories
Loading custom metrics...

FDMT vs QURE vs CRSP vs RCKT vs EDIT: Key Questions Answered

8 questions · data-driven answers · updated daily

01

Is FDMT or QURE or CRSP or RCKT or EDIT a better buy right now?

For growth investors, 4D Molecular Therapeutics, Inc.

(FDMT) is the stronger pick with 2302% revenue growth year-over-year, versus -100. 0% for Editas Medicine, Inc. (EDIT). Analysts rate 4D Molecular Therapeutics, Inc. (FDMT) a "Buy" — based on 14 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — FDMT or QURE or CRSP or RCKT or EDIT?

Over the past 5 years, uniQure N.

V. (QURE) delivered a total return of -25. 8%, compared to -91. 6% for Rocket Pharmaceuticals, Inc. (RCKT). Over 10 years, the gap is even starker: CRSP returned +289. 1% versus RCKT's -91. 4%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — FDMT or QURE or CRSP or RCKT or EDIT?

By beta (market sensitivity over 5 years), Rocket Pharmaceuticals, Inc.

(RCKT) is the lower-risk stock at 1. 21β versus Editas Medicine, Inc. 's 2. 45β — meaning EDIT is approximately 102% more volatile than RCKT relative to the S&P 500. On balance sheet safety, 4D Molecular Therapeutics, Inc. (FDMT) carries a lower debt/equity ratio of 4% versus 3% for uniQure N. V. — giving it more financial flexibility in a downturn.

04

Which is growing faster — FDMT or QURE or CRSP or RCKT or EDIT?

By revenue growth (latest reported year), 4D Molecular Therapeutics, Inc.

(FDMT) is pulling ahead at 2302% versus -100. 0% for Editas Medicine, Inc. (EDIT). On earnings-per-share growth, the picture is similar: Editas Medicine, Inc. grew EPS 37. 5% year-over-year, compared to -49. 1% for CRISPR Therapeutics AG. Over a 3-year CAGR, FDMT leads at 200. 9% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — FDMT or QURE or CRSP or RCKT or EDIT?

Rocket Pharmaceuticals, Inc.

(RCKT) is the more profitable company, earning 0. 0% net margin versus -165. 7% for CRISPR Therapeutics AG — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: RCKT leads at 0. 0% versus -161. 9% for CRSP. At the gross margin level — before operating expenses — FDMT leads at 91. 1%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Which pays a better dividend — FDMT or QURE or CRSP or RCKT or EDIT?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

07

Is FDMT or QURE or CRSP or RCKT or EDIT better for a retirement portfolio?

For long-horizon retirement investors, uniQure N.

V. (QURE) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 26)). Editas Medicine, Inc. (EDIT) carries a higher beta of 2. 45 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (QURE: +86. 3%, EDIT: -89. 7%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

08

What are the main differences between FDMT and QURE and CRSP and RCKT and EDIT?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: FDMT is a small-cap high-growth stock; QURE is a small-cap quality compounder stock; CRSP is a small-cap quality compounder stock; RCKT is a small-cap quality compounder stock; EDIT is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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