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FDMT logo4D Molecular Therapeutics, Inc.(FDMT)Earnings, Financials & Key Ratios

FDMT•NASDAQ
$10.42
$600M mkt cap·Price updated May 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryCell and Gene Therapy Developers
About4D Molecular Therapeutics, Inc., a clinical-stage gene therapy company, develops product candidates using its adeno-associated viruses vectors. It develops a portfolio of gene therapy product candidates focuses in three therapeutic areas: ophthalmology, cardiology, and pulmonology. The company has three product candidates that are in clinical trials: 4D-125 that is in a Phase 1/2 clinical trial for the treatment of X-linked retinitis pigmentosa; 4D-110 that is in a Phase 1/2 clinical trial for the treatment of choroideremia; and 4D-310, which is in a Phase 1/2 clinical trial for the treatment of Fabry disease. Its two IND candidates are 4D-150 for the treatment of wet age-related macular degeneration and 4D-710 for the treatment of cystic fibrosis lung disease. 4D Molecular Therapeutics, Inc. has research and collaboration arrangements with uniQure; CRF; Roche; and CFF. The company was founded in 2013 and is headquartered in Emeryville, California.4D Molecular Therapeutics, Inc., a clinical-stage gene therapy company, develops product candidates using its adeno-associated viruses vectors. It develops a portfolio of gene therapy product candidates focuses in three therapeutic areas: ophthalmology, cardiology, and pulmonology. The company has three product candidates that are in clinical trials: 4D-125 that is in a Phase 1/2 clinical trial for the treatment of X-linked retinitis pigmentosa; 4D-110 that is in a Phase 1/2 clinical trial for the treatment of choroideremia; and 4D-310, which is in a Phase 1/2 clinical trial for the treatment of Fabry disease. Its two IND candidates are 4D-150 for the treatment of wet age-related macular degeneration and 4D-710 for the treatment of cystic fibrosis lung disease. 4D Molecular Therapeutics, Inc. has research and collaboration arrangements with uniQure; CRF; Roche; and CFF. The company was founded in 2013 and is headquartered in Emeryville, California.Show more
  • Revenue$85M+230194.6%
  • EBITDA-$152M+16.1%
  • Net Income-$140M+12.9%
  • EPS (Diluted)-2.42+18.8%
  • Gross Margin91.05%-8.9%
  • EBITDA Margin-178.29%+100.0%
  • Operating Margin-187.24%+100.0%
  • Net Margin-164.43%+100.0%
  • ROE-27.57%+29.9%
  • ROIC-28.07%+54.3%
  • Debt/Equity0.04-12.1%
Technical→

FDMT Key Insights

4D Molecular Therapeutics, Inc. (FDMT) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Company is almost debt free
  • ✓Strong 5Y sales CAGR of 44.3%
  • ✓Trading at only 1.2x book value

✗Weaknesses

  • ✗Negative free cash flow
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

FDMT Price & Volume

4D Molecular Therapeutics, Inc. (FDMT) stock price & volume — 10-year historical chart

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FDMT Growth Metrics

4D Molecular Therapeutics, Inc. (FDMT) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years44.32%
3 Years200.86%
TTM230194.59%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM12.9%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM15.77%

Return on Capital

10 Years-39.81%
5 Years-35.07%
3 Years-38.06%
Last Year-30.28%

FDMT Recent Earnings

4D Molecular Therapeutics, Inc. (FDMT) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 5/12 qtrs (42%)●Beat Revenue 3/12 qtrs (25%)
Q2 2026Latest
Mar 18, 2026
EPS
$0.43
Est $0.53
+181.1%
Revenue
$85M
Est $27M
+215.2%
Q4 2025
Nov 10, 2025
EPS
$1.01
Est $1.02
+1.0%
Revenue
$90,000
Est $31M
-99.7%
Q3 2025
Aug 11, 2025
EPS
$0.98
Est $0.88
-11.4%
Revenue
$15,000
Est $4,670
+221.2%
Q2 2025
May 8, 2025
EPS
$0.86
Est $0.84
-2.4%
Revenue
$14,000
Est $537,500
-97.4%
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMar 18, 2026
$0.43vs $0.53+181.1%
$85Mvs $27M+215.2%
Q4 2025Nov 10, 2025
$1.01vs $1.02+1.0%
$90,000vs $31M-99.7%
Q3 2025Aug 11, 2025
$0.98vs $0.88-11.4%
$15,000vs $4,670+221.2%
Q2 2025May 8, 2025
$0.86vs $0.84-2.4%
$14,000vs $537,500-97.4%
Based on last 12 quarters of dataView full earnings history →

FDMT Peer Comparison

4D Molecular Therapeutics, Inc. (FDMT) competitors in Cell and Gene Therapy Developers — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
OCGN logoOCGNOcugen, Inc.Direct Competitor492.54M1.46-6.338.83%-15.37%-26.26%
KRYS logoKRYSKrystal Biotech, Inc.Direct Competitor8.52B288.9042.2433.94%53.92%19.25%0.01
RCKT logoRCKTRocket Pharmaceuticals, Inc.Direct Competitor418.11M3.86-1.92-80.49%0.09
QURE logoQUREuniQure N.V.Direct Competitor1.41B22.82-6.60-40.64%-11.54%-145.81%2.70
EDIT logoEDITEditas Medicine, Inc.Product Competitor310.73M3.18-1.76-100%-5.23%0.66
NTLA logoNTLAIntellia Therapeutics, Inc.Product Competitor1.61B13.85-3.64-100%-61.47%0.14
BEAM logoBEAMBeam Therapeutics Inc.Product Competitor3.32B32.33-39.92120.01%-57.24%-7.31%0.24
CRSP logoCRSPCRISPR Therapeutics AGProduct Competitor5.31B55.08-8.51-89.97%-138.57%-30.88%0.21

Compare FDMT vs Peers

4D Molecular Therapeutics, Inc. (FDMT) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs OCGN

Most directly comparable listed peer for FDMT.

Scale Benchmark

vs REGN

Larger-name benchmark to compare FDMT against a more recognizable public peer.

Peer Set

Compare Top 5

vs OCGN, KRYS, RCKT, QURE

FDMT Income Statement

4D Molecular Therapeutics, Inc. (FDMT) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Sales/Revenue5.79M14.13M6.99M13.61M18.04M3.13M20.72M37K85.21M
Revenue Growth %-144.04%-50.56%94.85%32.52%-82.65%562.29%-99.82%230194.59%
Cost of Goods Sold13.57M18.36M38.72M53.04M61.36M80.25M97.1M07.63M
COGS % of Revenue234.42%129.95%554.22%389.64%340.17%2564.81%468.54%-8.95%
Gross Profit
-7.78M▲ 0%
-4.23M▲ 45.6%
-31.73M▼ 649.8%
-39.43M▼ 24.2%
-43.32M▼ 9.9%
-77.12M▼ 78.0%
-76.37M▲ 1.0%
37K▲ 100.0%
77.58M▲ 209586.5%
Gross Margin %-134.42%-29.95%-454.22%-289.64%-240.17%-2464.81%-368.54%100%91.05%
Gross Profit Growth %-45.63%-649.81%-24.25%-9.88%-78.03%0.97%100.05%209586.49%
Operating Expenses17.06M24.53M19.03M17.24M28.01M32.91M36.49M187.88M237.13M
OpEx % of Revenue294.68%173.6%272.43%126.64%155.29%1051.71%176.1%507778.38%278.29%
Selling, General & Admin3.49M6.17M13.89M17.24M28.01M32.91M36.49M46.58M49.06M
SG&A % of Revenue60.26%43.64%198.9%126.64%155.29%1051.71%176.1%125889.19%57.58%
Research & Development13.57M18.36M43.85M53.04M61.36M80.25M97.1M141.3M195.7M
R&D % of Revenue234.42%129.95%627.76%389.64%340.17%2564.81%468.54%381889.19%229.67%
Other Operating Expenses-40K-2K-38.72M-53.04M-61.36M-80.25M-97.1M0-7.63M
Operating Income
-11.27M▲ 0%
-10.4M▲ 7.7%
-50.76M▼ 388.2%
-56.66M▼ 11.6%
-71.33M▼ 25.9%
-110.03M▼ 54.3%
-112.87M▼ 2.6%
-187.84M▼ 66.4%
-159.55M▲ 15.1%
Operating Margin %-194.68%-73.6%-726.65%-416.28%-395.46%-3516.52%-544.65%-507678.38%-187.24%
Operating Income Growth %-7.74%-388.16%-11.62%-25.89%-54.25%-2.58%-66.43%15.06%
EBITDA-10.65M-9.7M-49.76M-55.22M-69.81M-107.63M-108.66M-181.14M-151.92M
EBITDA Margin %-183.87%-68.66%-712.28%-405.68%-387.02%-3439.73%-524.36%-489556.76%-178.29%
EBITDA Growth %-8.87%-412.88%-10.97%-26.42%-54.17%-0.96%-66.7%16.13%
D&A (Non-Cash Add-back)626K697K1M1.44M1.52M2.4M4.2M6.71M7.63M
EBIT-11.27M-10.4M-45.63M-56.66M-71.33M-110.03M-112.87M-187.84M-159.55M
Net Interest Income89K850K1.5M152K137K2.57M12.21M27.05M19.48M
Interest Income89K850K1.5M152K137K2.57M12.21M27.05M19.48M
Interest Expense000000000
Other Income/Expense49K848K1.46M-29K16K2.54M12.03M26.97M19.44M
Pretax Income
-11.22M▲ 0%
-9.55M▲ 14.9%
-49.31M▼ 416.2%
-56.69M▼ 15.0%
-71.32M▼ 25.8%
-107.49M▼ 50.7%
-100.84M▲ 6.2%
-160.87M▼ 59.5%
-140.11M▲ 12.9%
Pretax Margin %-193.83%-67.59%-705.78%-416.49%-395.37%-3435.41%-486.59%-434778.38%-164.43%
Income Tax-89K00000000
Effective Tax Rate %0.79%0%0%0%0%0%0%0%0%
Net Income
-11.22M▲ 0%
-9.55M▲ 14.9%
-49.31M▼ 416.2%
-56.69M▼ 15.0%
-71.32M▼ 25.8%
-107.49M▼ 50.7%
-100.84M▲ 6.2%
-160.87M▼ 59.5%
-140.11M▲ 12.9%
Net Margin %-193.83%-67.59%-705.78%-416.49%-395.37%-3435.41%-486.59%-434778.38%-164.43%
Net Income Growth %-14.9%-416.24%-14.98%-25.8%-50.73%6.19%-59.53%12.9%
Net Income (Continuing)-11.22M-9.55M-49.31M-56.69M-71.32M-107.49M-100.84M-160.87M-140.11M
Discontinued Operations000000000
Minority Interest000000000
EPS (Diluted)
-0.76▲ 0%
-0.76▲ 0.0%
-2.00▼ 163.2%
-2.12▼ 6.0%
-2.46▼ 16.0%
-3.12▼ 26.8%
-2.58▲ 17.3%
-2.98▼ 15.5%
-2.42▲ 18.8%
EPS Growth %-0%-163.16%-6%-16.04%-26.83%17.31%-15.5%18.79%
EPS (Basic)-0.76-0.76-2.00-2.12-2.46-3.12-2.58-2.98-2.42
Diluted Shares Outstanding14.84M12.52M26.49M26.68M27.73M32.35M39.13M53.94M57.93M
Basic Shares Outstanding14.84M12.52M26.49M26.68M27.73M32.35M39.13M53.94M57.93M
Dividend Payout Ratio---------

FDMT Balance Sheet

4D Molecular Therapeutics, Inc. (FDMT) balance sheet — assets, liabilities & shareholders' equity

Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Total Current Assets24.5M94.07M52.51M282.66M256.28M220.51M296.59M434.93M413.13M
Cash & Short-Term Investments23.85M91.76M49.65M276.73M247.78M213.55M288.23M424.88M402.65M
Cash Only23.85M91.76M49.65M276.73M153M52.35M249.11M149.34M60.24M
Short-Term Investments000094.78M161.2M39.12M275.54M342.41M
Accounts Receivable321K1.12M978K1.49M47K700K000
Days Sales Outstanding20.2429.0351.139.850.9581.66---
Inventory000000000
Days Inventory Outstanding---------
Other Current Assets0004.44M06.26M8.36M10.05M10.48M
Total Non-Current Assets2.82M2.9M5.73M5.67M97.21M41.34M43.3M125.45M153.58M
Property, Plant & Equipment2.72M2.47M5.05M5.07M28.95M35.35M31.66M40.61M33.01M
Fixed Asset Turnover2.13x5.72x1.38x2.68x0.62x0.09x0.65x0.00x2.58x
Goodwill000000000
Intangible Assets000000000
Long-Term Investments000067.65M4.91M10.95M80.58M0
Other Non-Current Assets105K429K677K602K602K1.08M684K4.26M120.57M
Total Assets
27.32M▲ 0%
96.97M▲ 254.9%
58.23M▼ 39.9%
288.33M▲ 395.1%
353.49M▲ 22.6%
261.85M▼ 25.9%
339.89M▲ 29.8%
560.38M▲ 64.9%
566.71M▲ 1.1%
Asset Turnover0.21x0.15x0.12x0.05x0.05x0.01x0.06x0.00x0.15x
Asset Growth %-254.94%-39.95%395.12%22.6%-25.92%29.81%64.87%1.13%
Total Current Liabilities5.91M8.05M12.96M16.74M16.34M15.73M18.95M29.15M43.98M
Accounts Payable460K954K1.74M1.79M4.76M3.32M3.52M4.39M11.16M
Days Payables Outstanding12.3718.9616.4412.328.3415.1113.21-534.17
Short-Term Debt000002.65M005.59M
Deferred Revenue (Current)4.38M4.91M5.86M6.59M2.6M884K273K257K360K
Other Current Liabilities279K00003.18M3.87M026.87M
Current Ratio4.15x11.68x4.05x16.88x15.69x14.02x15.65x14.92x9.39x
Quick Ratio4.15x11.68x4.05x16.88x15.69x14.02x15.65x14.92x9.39x
Cash Conversion Cycle---------
Total Non-Current Liabilities41M116.5M118.25M15.2M18.04M14.78M13.11M20.63M17.06M
Long-Term Debt0000000015.82M
Capital Lease Obligations000015.22M13.47M11.52M18.97M0
Deferred Tax Liabilities000000000
Other Non-Current Liabilities18.81M103.43M104.65M1.97M334K233K617K603K496K
Total Liabilities46.91M124.56M131.2M31.94M34.38M30.51M32.06M49.78M61.05M
Total Debt000016.45M16.12M14.67M24.61M21.41M
Net Debt-23.85M-91.76M-49.65M-276.73M-136.55M-36.23M-234.44M-124.73M-38.83M
Debt / Equity----0.05x0.07x0.05x0.05x0.04x
Debt / EBITDA---------
Net Debt / EBITDA---------
Interest Coverage---------
Total Equity
-19.59M▲ 0%
-27.59M▼ 40.8%
-72.97M▼ 164.5%
256.39M▲ 451.4%
319.11M▲ 24.5%
231.34M▼ 27.5%
307.83M▲ 33.1%
510.61M▲ 65.9%
505.66M▼ 1.0%
Equity Growth %--40.82%-164.51%451.36%24.46%-27.5%33.07%65.87%-0.97%
Book Value per Share-1.32-2.20-2.759.6111.517.157.879.478.73
Total Shareholders' Equity-19.59M-27.59M-72.97M256.39M319.11M231.34M307.83M510.61M505.66M
Common Stock1K1K1K3K3K3K4K5K6K
Retained Earnings-20.48M-30.03M-79.03M-135.68M-207M-314.49M-415.33M-576.2M-716.3M
Treasury Stock000000000
Accumulated OCI-18.51M-102.98M-102.98M-288.33M-423K-1.2M16K229K727K
Minority Interest000000000

FDMT Cash Flow Statement

4D Molecular Therapeutics, Inc. (FDMT) cash flow — operating, investing & free cash flow history

Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Cash from Operations8.24M-16.25M-36.71M-50.91M-69.13M-86.69M-75.79M-134.59M-109.08M
Operating CF Margin %142.26%-115.02%-525.49%-374%-383.27%-2770.37%-365.74%-363743.24%-128.02%
Operating CF Growth %--297.3%-125.89%-38.68%-35.8%-25.39%12.57%-77.57%18.95%
Net Income-11.22M-9.55M-49.31M-56.69M-71.32M-107.49M-100.84M-160.87M-140.11M
Depreciation & Amortization626K697K1M1.44M3.02M3.88M5.75M6.71M7.63M
Stock-Based Compensation256K1.38M3.54M4.98M13.8M17.12M19.66M26.12M22.02M
Deferred Taxes000000000
Other Non-Cash Items39K2K7.79M69K898K1.14M-999K-7.08M-4.79M
Working Capital Changes18.54M-8.78M259K-712K-15.53M-1.34M630K537K6.17M
Change in Receivables-320K-803K146K-508K1.44M47K000
Change in Inventory-53K175K00-4.54M0000
Change in Payables-114K438K533K43K2.29M-1.64M896K871K6.77M
Cash from Investing7.67M-414K-3.2M-1M-172.68M-17.05M115.72M-302.44M-92.97M
Capital Expenditures-573K-414K-3.2M-1M-9.11M-11.54M-2.77M-3.79M-536K
CapEx % of Revenue9.9%2.93%45.85%7.35%50.5%368.68%13.37%10232.43%0.63%
Acquisitions24K0009.11M0000
Investments---------
Other Investing24K000-9.11M0173.29M00
Cash from Financing16K84.58M-2.19M278.98M118.09M3.08M156.83M337.25M112.96M
Debt Issued (Net)000000000
Equity Issued (Net)16K0-1000K1000K1000K1000K1000K1000K1000K
Dividends Paid000000000
Share Repurchases000000000
Other Financing084.58M0857K3.79M08.49M5.84M0
Net Change in Cash
15.93M▲ 0%
67.91M▲ 326.4%
-42.11M▼ 162.0%
227.07M▲ 639.3%
-123.72M▼ 154.5%
-100.65M▲ 18.7%
196.76M▲ 295.5%
-99.77M▼ 150.7%
-89.09M▲ 10.7%
Free Cash Flow
7.66M▲ 0%
-16.67M▼ 317.5%
-39.91M▼ 139.5%
-51.91M▼ 30.1%
-78.24M▼ 50.7%
-98.22M▼ 25.5%
-78.56M▲ 20.0%
-138.37M▼ 76.1%
-109.08M▲ 21.2%
FCF Margin %132.37%-117.95%-571.34%-381.35%-433.77%-3139.05%-379.11%-373975.68%-128.02%
FCF Growth %--317.46%-139.49%-30.05%-50.73%-25.53%20.01%-76.13%21.17%
FCF per Share0.52-1.33-1.51-1.95-2.82-3.04-2.01-2.57-1.88
FCF Conversion (FCF/Net Income)-0.73x1.70x0.74x0.90x0.97x0.81x0.75x0.84x0.78x
Interest Paid000000000
Taxes Paid000000000

FDMT Key Ratios

4D Molecular Therapeutics, Inc. (FDMT) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric201720182019202020212022202320242025
Return on Equity (ROE)----61.82%-24.78%-39.06%-37.4%-39.31%-27.57%
Return on Invested Capital (ROIC)-----65.96%-43.7%-63.05%-61.35%-28.07%
Gross Margin-134.42%-29.95%-454.22%-289.64%-240.17%-2464.81%-368.54%100%91.05%
Net Margin-193.83%-67.59%-705.78%-416.49%-395.37%-3435.41%-486.59%-434778.38%-164.43%
Debt / Equity----0.05x0.07x0.05x0.05x0.04x
FCF Conversion-0.73x1.70x0.74x0.90x0.97x0.81x0.75x0.84x0.78x
Revenue Growth-144.04%-50.56%94.85%32.52%-82.65%562.29%-99.82%230194.59%

FDMT SEC Filings & Documents

4D Molecular Therapeutics, Inc. (FDMT) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Mar 30, 2026·SEC

Material company update

Mar 18, 2026·SEC

Material company update

Jan 26, 2026·SEC

10-K Annual Reports

3
FY 2026

Mar 18, 2026·SEC

FY 2025

Feb 28, 2025·SEC

FY 2024

Feb 29, 2024·SEC

10-Q Quarterly Reports

6
FY 2025

Nov 10, 2025·SEC

FY 2025

Aug 11, 2025·SEC

FY 2025

May 8, 2025·SEC

FDMT Frequently Asked Questions

4D Molecular Therapeutics, Inc. (FDMT) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

4D Molecular Therapeutics, Inc. (FDMT) reported $85.2M in revenue for fiscal year 2025. This represents a 1372% increase from $5.8M in 2017.

4D Molecular Therapeutics, Inc. (FDMT) grew revenue by 230194.6% over the past year. This is strong growth.

4D Molecular Therapeutics, Inc. (FDMT) reported a net loss of $140.1M for fiscal year 2025.

Dividend & Returns

4D Molecular Therapeutics, Inc. (FDMT) has a return on equity (ROE) of -27.6%. Negative ROE indicates the company is unprofitable.

4D Molecular Therapeutics, Inc. (FDMT) had negative free cash flow of $110.3M in fiscal year 2025, likely due to heavy capital investments.

Explore More FDMT

4D Molecular Therapeutics, Inc. (FDMT) financial analysis — history, returns, DCA and operating performance tools

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Historical returns with dividends reinvested

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Dividend History

Yield, growth, payout safety & DRIP

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Earnings History

EPS trends, net income & profitability

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Price History

Long-term charts & historical price data

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Revenue History

Sales growth patterns & revenue breakdown

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Financial Ratios

30 years of market, efficiency and balance-sheet ratios

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Valuation

DCF intrinsic value, peer multiples & estimates

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