Biotechnology
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5 / 10Stock Comparison
FENC vs SNOA vs HALO vs PRGO vs INVA
Revenue, margins, valuation, and 5-year total return — side by side.
Drug Manufacturers - Specialty & Generic
Biotechnology
Drug Manufacturers - Specialty & Generic
Biotechnology
FENC vs SNOA vs HALO vs PRGO vs INVA — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Drug Manufacturers - Specialty & Generic | Biotechnology | Drug Manufacturers - Specialty & Generic | Biotechnology |
| Market Cap | $194M | $2M | $7.55B | $1.62B | $1.69B |
| Revenue (TTM) | $39M | $18M | $1.40B | $4.18B | $424M |
| Net Income (TTM) | $-7M | $-3M | $317M | $-1.82B | $504M |
| Gross Margin | 93.1% | 38.2% | 81.9% | 34.2% | 76.2% |
| Operating Margin | -12.0% | -15.6% | 58.4% | -4.1% | 14.8% |
| Forward P/E | 54.3x | — | 8.0x | 5.5x | 7.3x |
| Total Debt | $19M | $305K | $0.00 | $3.97B | $269M |
| Cash & Equiv. | $27M | $5M | $134M | $532M | $551M |
FENC vs SNOA vs HALO vs PRGO vs INVA — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Fennec Pharmaceutic… (FENC) | 100 | 93.6 | -6.4% |
| Sonoma Pharmaceutic… (SNOA) | 100 | 0.6 | -99.4% |
| Halozyme Therapeuti… (HALO) | 100 | 264.2 | +164.2% |
| Perrigo Company plc (PRGO) | 100 | 21.4 | -78.6% |
| Innoviva, Inc. (INVA) | 100 | 163.9 | +63.9% |
Price return only. Dividends and distributions are not included.
Quick Verdict: FENC vs SNOA vs HALO vs PRGO vs INVA
Each card shows where this stock fits in a portfolio — not just who wins on paper.
FENC is the #2 pick in this set and the best alternative if growth is your priority.
- 123.7% revenue growth vs PRGO's -2.8%
Among these 5 stocks, SNOA doesn't own a clear edge in any measured category.
HALO ranks third and is worth considering specifically for long-term compounding and valuation efficiency.
- 5.6% 10Y total return vs INVA's 95.6%
- PEG 0.35 vs INVA's 0.71
- PEG 0.35 vs 0.71
PRGO is the clearest fit if your priority is dividends.
- 9.8% yield; 10-year raise streak; the other 4 pay no meaningful dividend
INVA carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- Dividend streak 0 yrs, beta 0.11
- Rev growth 18.5%, EPS growth 8.2%, 3Y rev CAGR 8.7%
- Lower volatility, beta 0.11, Low D/E 22.9%, current ratio 14.64x
- Beta 0.11, current ratio 14.64x
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 123.7% revenue growth vs PRGO's -2.8% | |
| Value | PEG 0.35 vs 0.71 | |
| Quality / Margins | 118.9% margin vs PRGO's -43.5% | |
| Stability / Safety | Beta 0.11 vs FENC's 1.78 | |
| Dividends | 9.8% yield; 10-year raise streak; the other 4 pay no meaningful dividend | |
| Momentum (1Y) | +23.2% vs SNOA's -62.6% | |
| Efficiency (ROA) | 32.4% ROA vs SNOA's -24.7%, ROIC 14.2% vs -188.1% |
FENC vs SNOA vs HALO vs PRGO vs INVA — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
FENC vs SNOA vs HALO vs PRGO vs INVA — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
HALO leads in 1 of 6 categories
INVA leads 1 • PRGO leads 1 • FENC leads 0 • SNOA leads 0 • 3 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
Evenly matched — FENC and HALO and INVA each lead in 2 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
PRGO is the larger business by revenue, generating $4.2B annually — 235.8x SNOA's $18M. INVA is the more profitable business, keeping 118.9% of every revenue dollar as net income compared to PRGO's -43.5%. On growth, FENC holds the edge at +78.7% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $39M | $18M | $1.4B | $4.2B | $424M |
| EBITDAEarnings before interest/tax | -$5M | -$3M | $945M | $58M | $86M |
| Net IncomeAfter-tax profit | -$7M | -$3M | $317M | -$1.8B | $504M |
| Free Cash FlowCash after capex | -$8M | -$3M | $645M | $108M | $181M |
| Gross MarginGross profit ÷ Revenue | +93.1% | +38.2% | +81.9% | +34.2% | +76.2% |
| Operating MarginEBIT ÷ Revenue | -12.0% | -15.6% | +58.4% | -4.1% | +14.8% |
| Net MarginNet income ÷ Revenue | -17.9% | -19.0% | +22.7% | -43.5% | +118.9% |
| FCF MarginFCF ÷ Revenue | -20.6% | -17.0% | +46.2% | +2.6% | +42.6% |
| Rev. Growth (YoY)Latest quarter vs prior year | +78.7% | +22.0% | +51.6% | -7.2% | +10.6% |
| EPS Growth (YoY)Latest quarter vs prior year | +89.1% | +23.8% | -2.1% | -56.4% | +4.0% |
Valuation Metrics
Evenly matched — FENC and SNOA and INVA each lead in 2 of 7 comparable metrics.
Valuation Metrics
At 6.9x trailing earnings, INVA trades at a 72% valuation discount to HALO's 25.0x P/E. Adjusting for growth (PEG ratio), INVA offers better value at 0.67x vs HALO's 1.09x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $194M | $2M | $7.6B | $1.6B | $1.7B |
| Enterprise ValueMkt cap + debt − cash | $187M | -$3M | $7.4B | $5.1B | $1.4B |
| Trailing P/EPrice ÷ TTM EPS | -433.13x | -0.43x | 25.05x | -1.14x | 6.94x |
| Forward P/EPrice ÷ next-FY EPS est. | 54.27x | — | 7.96x | 5.53x | 7.31x |
| PEG RatioP/E ÷ EPS growth rate | — | — | 1.09x | — | 0.67x |
| EV / EBITDAEnterprise value multiple | 55.57x | — | 8.20x | 7.43x | 6.90x |
| Price / SalesMarket cap ÷ Revenue | 4.09x | 0.15x | 5.41x | 0.38x | 3.97x |
| Price / BookPrice ÷ Book value/share | — | 0.34x | 162.76x | 0.55x | 1.65x |
| Price / FCFMarket cap ÷ FCF | 7.21x | — | 11.72x | 11.17x | 8.63x |
Profitability & Efficiency
HALO leads this category, winning 4 of 9 comparable metrics.
Profitability & Efficiency
HALO delivers a 6.5% return on equity — every $100 of shareholder capital generates $6 in annual profit, vs $-98 for SNOA. SNOA carries lower financial leverage with a 0.07x debt-to-equity ratio, signaling a more conservative balance sheet compared to PRGO's 1.35x. On the Piotroski fundamental quality scale (0–9), FENC scores 6/9 vs PRGO's 4/9, reflecting solid financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | — | -98.2% | +6.5% | -50.7% | +47.6% |
| ROA (TTM)Return on assets | -15.0% | -24.7% | +12.5% | -19.8% | +32.4% |
| ROICReturn on invested capital | — | -188.1% | +73.4% | +3.7% | +14.2% |
| ROCEReturn on capital employed | +9.0% | -36.0% | +38.2% | +4.3% | +12.4% |
| Piotroski ScoreFundamental quality 0–9 | 6 | 5 | 5 | 4 | 5 |
| Debt / EquityFinancial leverage | — | 0.07x | — | 1.35x | 0.23x |
| Net DebtTotal debt minus cash | -$7M | -$5M | -$134M | $3.4B | -$282M |
| Cash & Equiv.Liquid assets | $27M | $5M | $134M | $532M | $551M |
| Total DebtShort + long-term debt | $19M | $305,000 | $0 | $4.0B | $269M |
| Interest CoverageEBIT ÷ Interest expense | -1.57x | — | 46.08x | -7.20x | 63.45x |
Total Returns (Dividends Reinvested)
Evenly matched — HALO and INVA each lead in 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in INVA five years ago would be worth $19,448 today (with dividends reinvested), compared to $82 for SNOA. Over the past 12 months, INVA leads with a +23.2% total return vs SNOA's -62.6%. The 3-year compound annual growth rate (CAGR) favors HALO at 28.4% vs SNOA's -60.7% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -9.8% | -67.0% | -8.8% | -13.6% | +15.2% |
| 1-Year ReturnPast 12 months | +11.6% | -62.6% | -5.3% | -52.0% | +23.2% |
| 3-Year ReturnCumulative with dividends | -12.8% | -94.0% | +111.8% | -58.1% | +96.0% |
| 5-Year ReturnCumulative with dividends | +15.9% | -99.2% | +39.1% | -60.3% | +94.5% |
| 10-Year ReturnCumulative with dividends | -42.3% | -99.9% | +559.7% | -77.7% | +95.6% |
| CAGR (3Y)Annualised 3-year return | -4.5% | -60.7% | +28.4% | -25.2% | +25.1% |
Risk & Volatility
INVA leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
INVA is the less volatile stock with a 0.11 beta — it tends to amplify market swings less than FENC's 1.78 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. INVA currently trades 91.0% from its 52-week high vs SNOA's 17.3% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.78x | 0.84x | 0.51x | 1.21x | 0.11x |
| 52-Week HighHighest price in past year | $9.92 | $6.92 | $82.22 | $28.44 | $25.15 |
| 52-Week LowLowest price in past year | $5.65 | $0.85 | $47.50 | $9.23 | $16.52 |
| % of 52W HighCurrent price vs 52-week peak | +69.9% | +17.3% | +78.0% | +41.2% | +91.0% |
| RSI (14)Momentum oscillator 0–100 | 53.4 | 31.3 | 47.7 | 53.1 | 44.7 |
| Avg Volume (50D)Average daily shares traded | 177K | 189K | 1.4M | 3.3M | 604K |
Analyst Outlook
PRGO leads this category, winning 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: FENC as "Buy", HALO as "Buy", PRGO as "Hold", INVA as "Buy". Consensus price targets imply 209.1% upside for PRGO (target: $36) vs 17.9% for HALO (target: $76). PRGO is the only dividend payer here at 9.82% yield — a key consideration for income-focused portfolios.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | — | Buy | Hold | Buy |
| Price TargetConsensus 12-month target | $18.00 | — | $75.60 | $36.20 | $40.00 |
| # AnalystsCovering analysts | 7 | — | 27 | 36 | 10 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | +9.8% | — |
| Dividend StreakConsecutive years of raises | — | — | — | 10 | 0 |
| Dividend / ShareAnnual DPS | — | — | — | $1.15 | — |
| Buyback YieldShare repurchases ÷ mkt cap | +0.1% | +0.0% | +4.5% | 0.0% | +0.3% |
HALO leads in 1 of 6 categories (Profitability & Efficiency). INVA leads in 1 (Risk & Volatility). 3 tied.
FENC vs SNOA vs HALO vs PRGO vs INVA: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is FENC or SNOA or HALO or PRGO or INVA a better buy right now?
For growth investors, Fennec Pharmaceuticals Inc.
(FENC) is the stronger pick with 123. 7% revenue growth year-over-year, versus -2. 8% for Perrigo Company plc (PRGO). Innoviva, Inc. (INVA) offers the better valuation at 6. 9x trailing P/E (7. 3x forward), making it the more compelling value choice. Analysts rate Fennec Pharmaceuticals Inc. (FENC) a "Buy" — based on 7 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — FENC or SNOA or HALO or PRGO or INVA?
On trailing P/E, Innoviva, Inc.
(INVA) is the cheapest at 6. 9x versus Halozyme Therapeutics, Inc. at 25. 0x. On forward P/E, Perrigo Company plc is actually cheaper at 5. 5x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Halozyme Therapeutics, Inc. wins at 0. 35x versus Innoviva, Inc. 's 0. 71x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.
03Which is the better long-term investment — FENC or SNOA or HALO or PRGO or INVA?
Over the past 5 years, Innoviva, Inc.
(INVA) delivered a total return of +94. 5%, compared to -99. 2% for Sonoma Pharmaceuticals, Inc. (SNOA). Over 10 years, the gap is even starker: HALO returned +559. 7% versus SNOA's -99. 9%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — FENC or SNOA or HALO or PRGO or INVA?
By beta (market sensitivity over 5 years), Innoviva, Inc.
(INVA) is the lower-risk stock at 0. 11β versus Fennec Pharmaceuticals Inc. 's 1. 78β — meaning FENC is approximately 1462% more volatile than INVA relative to the S&P 500. On balance sheet safety, Sonoma Pharmaceuticals, Inc. (SNOA) carries a lower debt/equity ratio of 7% versus 135% for Perrigo Company plc — giving it more financial flexibility in a downturn.
05Which is growing faster — FENC or SNOA or HALO or PRGO or INVA?
By revenue growth (latest reported year), Fennec Pharmaceuticals Inc.
(FENC) is pulling ahead at 123. 7% versus -2. 8% for Perrigo Company plc (PRGO). On earnings-per-share growth, the picture is similar: Innoviva, Inc. grew EPS 816. 7% year-over-year, compared to -723. 2% for Perrigo Company plc. Over a 3-year CAGR, HALO leads at 28. 4% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — FENC or SNOA or HALO or PRGO or INVA?
Innoviva, Inc.
(INVA) is the more profitable company, earning 63. 8% net margin versus -33. 5% for Perrigo Company plc — meaning it keeps 63. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: HALO leads at 58. 4% versus -26. 0% for SNOA. At the gross margin level — before operating expenses — FENC leads at 93. 3%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is FENC or SNOA or HALO or PRGO or INVA more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, Halozyme Therapeutics, Inc. (HALO) is the more undervalued stock at a PEG of 0. 35x versus Innoviva, Inc. 's 0. 71x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Perrigo Company plc (PRGO) trades at 5. 5x forward P/E versus 54. 3x for Fennec Pharmaceuticals Inc. — 48. 7x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for PRGO: 209. 1% to $36. 20.
08Which pays a better dividend — FENC or SNOA or HALO or PRGO or INVA?
In this comparison, PRGO (9.
8% yield) pays a dividend. FENC, SNOA, HALO, INVA do not pay a meaningful dividend and should not be held primarily for income.
09Is FENC or SNOA or HALO or PRGO or INVA better for a retirement portfolio?
For long-horizon retirement investors, Innoviva, Inc.
(INVA) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 11)). Fennec Pharmaceuticals Inc. (FENC) carries a higher beta of 1. 78 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (INVA: +95. 6%, FENC: -42. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between FENC and SNOA and HALO and PRGO and INVA?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: FENC is a small-cap high-growth stock; SNOA is a small-cap quality compounder stock; HALO is a small-cap high-growth stock; PRGO is a small-cap income-oriented stock; INVA is a small-cap high-growth stock. PRGO pays a dividend while FENC, SNOA, HALO, INVA do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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