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FENC vs SNOA vs HALO vs PRGO vs INVA

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
FENC
Fennec Pharmaceuticals Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$194M
5Y Perf.-6.4%
SNOA
Sonoma Pharmaceuticals, Inc.

Drug Manufacturers - Specialty & Generic

HealthcareNASDAQ • US
Market Cap$2M
5Y Perf.-99.4%
HALO
Halozyme Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$7.55B
5Y Perf.+164.2%
PRGO
Perrigo Company plc

Drug Manufacturers - Specialty & Generic

HealthcareNYSE • IE
Market Cap$1.62B
5Y Perf.-78.6%
INVA
Innoviva, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.69B
5Y Perf.+63.9%

FENC vs SNOA vs HALO vs PRGO vs INVA — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
FENC logoFENC
SNOA logoSNOA
HALO logoHALO
PRGO logoPRGO
INVA logoINVA
IndustryBiotechnologyDrug Manufacturers - Specialty & GenericBiotechnologyDrug Manufacturers - Specialty & GenericBiotechnology
Market Cap$194M$2M$7.55B$1.62B$1.69B
Revenue (TTM)$39M$18M$1.40B$4.18B$424M
Net Income (TTM)$-7M$-3M$317M$-1.82B$504M
Gross Margin93.1%38.2%81.9%34.2%76.2%
Operating Margin-12.0%-15.6%58.4%-4.1%14.8%
Forward P/E54.3x8.0x5.5x7.3x
Total Debt$19M$305K$0.00$3.97B$269M
Cash & Equiv.$27M$5M$134M$532M$551M

FENC vs SNOA vs HALO vs PRGO vs INVALong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

FENC
SNOA
HALO
PRGO
INVA
StockMay 20May 26Return
Fennec Pharmaceutic… (FENC)10093.6-6.4%
Sonoma Pharmaceutic… (SNOA)1000.6-99.4%
Halozyme Therapeuti… (HALO)100264.2+164.2%
Perrigo Company plc (PRGO)10021.4-78.6%
Innoviva, Inc. (INVA)100163.9+63.9%

Price return only. Dividends and distributions are not included.

Quick Verdict: FENC vs SNOA vs HALO vs PRGO vs INVA

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: INVA leads in 4 of 7 categories (5-stock set), making it the strongest pick for profitability and margin quality and capital preservation and lower volatility. Fennec Pharmaceuticals Inc. is the stronger pick specifically for growth and revenue expansion. HALO and PRGO also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
FENC
Fennec Pharmaceuticals Inc.
The Growth Leader

FENC is the #2 pick in this set and the best alternative if growth is your priority.

  • 123.7% revenue growth vs PRGO's -2.8%
Best for: growth
SNOA
Sonoma Pharmaceuticals, Inc.
The Healthcare Pick

Among these 5 stocks, SNOA doesn't own a clear edge in any measured category.

Best for: healthcare exposure
HALO
Halozyme Therapeutics, Inc.
The Long-Run Compounder

HALO ranks third and is worth considering specifically for long-term compounding and valuation efficiency.

  • 5.6% 10Y total return vs INVA's 95.6%
  • PEG 0.35 vs INVA's 0.71
  • PEG 0.35 vs 0.71
Best for: long-term compounding and valuation efficiency
PRGO
Perrigo Company plc
The Income Pick

PRGO is the clearest fit if your priority is dividends.

  • 9.8% yield; 10-year raise streak; the other 4 pay no meaningful dividend
Best for: dividends
INVA
Innoviva, Inc.
The Income Pick

INVA carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.

  • Dividend streak 0 yrs, beta 0.11
  • Rev growth 18.5%, EPS growth 8.2%, 3Y rev CAGR 8.7%
  • Lower volatility, beta 0.11, Low D/E 22.9%, current ratio 14.64x
  • Beta 0.11, current ratio 14.64x
Best for: income & stability and growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthFENC logoFENC123.7% revenue growth vs PRGO's -2.8%
ValueHALO logoHALOPEG 0.35 vs 0.71
Quality / MarginsINVA logoINVA118.9% margin vs PRGO's -43.5%
Stability / SafetyINVA logoINVABeta 0.11 vs FENC's 1.78
DividendsPRGO logoPRGO9.8% yield; 10-year raise streak; the other 4 pay no meaningful dividend
Momentum (1Y)INVA logoINVA+23.2% vs SNOA's -62.6%
Efficiency (ROA)INVA logoINVA32.4% ROA vs SNOA's -24.7%, ROIC 14.2% vs -188.1%

FENC vs SNOA vs HALO vs PRGO vs INVA — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

FENCFennec Pharmaceuticals Inc.
FY 2020
Royalty
100.0%$170,000
SNOASonoma Pharmaceuticals, Inc.
FY 2025
Human Care
84.5%$12M
Animal Care
11.6%$2M
Service And Royalty
3.9%$556,000
HALOHalozyme Therapeutics, Inc.
FY 2025
Royalty
53.6%$868M
Product
23.3%$376M
Collaborative Agreements
9.4%$152M
Bulk rHuPH20
8.2%$133M
Sales-based milestone
4.3%$70M
Upfront Fees
1.1%$18M
PRGOPerrigo Company plc
FY 2025
Consumer Self-Care Americas
60.8%$2.6B
Consumer Self-Care International
39.2%$1.7B
INVAInnoviva, Inc.
FY 2025
Royalty
57.5%$236M
Product
41.8%$172M
License And Other Revenue
0.7%$3M

FENC vs SNOA vs HALO vs PRGO vs INVA — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLHALOLAGGINGSNOA

Income & Cash Flow (Last 12 Months)

Evenly matched — FENC and HALO and INVA each lead in 2 of 6 comparable metrics.

PRGO is the larger business by revenue, generating $4.2B annually — 235.8x SNOA's $18M. INVA is the more profitable business, keeping 118.9% of every revenue dollar as net income compared to PRGO's -43.5%. On growth, FENC holds the edge at +78.7% YoY revenue growth, suggesting stronger near-term business momentum.

MetricFENC logoFENCFennec Pharmaceut…SNOA logoSNOASonoma Pharmaceut…HALO logoHALOHalozyme Therapeu…PRGO logoPRGOPerrigo Company p…INVA logoINVAInnoviva, Inc.
RevenueTrailing 12 months$39M$18M$1.4B$4.2B$424M
EBITDAEarnings before interest/tax-$5M-$3M$945M$58M$86M
Net IncomeAfter-tax profit-$7M-$3M$317M-$1.8B$504M
Free Cash FlowCash after capex-$8M-$3M$645M$108M$181M
Gross MarginGross profit ÷ Revenue+93.1%+38.2%+81.9%+34.2%+76.2%
Operating MarginEBIT ÷ Revenue-12.0%-15.6%+58.4%-4.1%+14.8%
Net MarginNet income ÷ Revenue-17.9%-19.0%+22.7%-43.5%+118.9%
FCF MarginFCF ÷ Revenue-20.6%-17.0%+46.2%+2.6%+42.6%
Rev. Growth (YoY)Latest quarter vs prior year+78.7%+22.0%+51.6%-7.2%+10.6%
EPS Growth (YoY)Latest quarter vs prior year+89.1%+23.8%-2.1%-56.4%+4.0%
Evenly matched — FENC and HALO and INVA each lead in 2 of 6 comparable metrics.

Valuation Metrics

Evenly matched — FENC and SNOA and INVA each lead in 2 of 7 comparable metrics.

At 6.9x trailing earnings, INVA trades at a 72% valuation discount to HALO's 25.0x P/E. Adjusting for growth (PEG ratio), INVA offers better value at 0.67x vs HALO's 1.09x — a lower PEG means you pay less per unit of expected earnings growth.

MetricFENC logoFENCFennec Pharmaceut…SNOA logoSNOASonoma Pharmaceut…HALO logoHALOHalozyme Therapeu…PRGO logoPRGOPerrigo Company p…INVA logoINVAInnoviva, Inc.
Market CapShares × price$194M$2M$7.6B$1.6B$1.7B
Enterprise ValueMkt cap + debt − cash$187M-$3M$7.4B$5.1B$1.4B
Trailing P/EPrice ÷ TTM EPS-433.13x-0.43x25.05x-1.14x6.94x
Forward P/EPrice ÷ next-FY EPS est.54.27x7.96x5.53x7.31x
PEG RatioP/E ÷ EPS growth rate1.09x0.67x
EV / EBITDAEnterprise value multiple55.57x8.20x7.43x6.90x
Price / SalesMarket cap ÷ Revenue4.09x0.15x5.41x0.38x3.97x
Price / BookPrice ÷ Book value/share0.34x162.76x0.55x1.65x
Price / FCFMarket cap ÷ FCF7.21x11.72x11.17x8.63x
Evenly matched — FENC and SNOA and INVA each lead in 2 of 7 comparable metrics.

Profitability & Efficiency

HALO leads this category, winning 4 of 9 comparable metrics.

HALO delivers a 6.5% return on equity — every $100 of shareholder capital generates $6 in annual profit, vs $-98 for SNOA. SNOA carries lower financial leverage with a 0.07x debt-to-equity ratio, signaling a more conservative balance sheet compared to PRGO's 1.35x. On the Piotroski fundamental quality scale (0–9), FENC scores 6/9 vs PRGO's 4/9, reflecting solid financial health.

MetricFENC logoFENCFennec Pharmaceut…SNOA logoSNOASonoma Pharmaceut…HALO logoHALOHalozyme Therapeu…PRGO logoPRGOPerrigo Company p…INVA logoINVAInnoviva, Inc.
ROE (TTM)Return on equity-98.2%+6.5%-50.7%+47.6%
ROA (TTM)Return on assets-15.0%-24.7%+12.5%-19.8%+32.4%
ROICReturn on invested capital-188.1%+73.4%+3.7%+14.2%
ROCEReturn on capital employed+9.0%-36.0%+38.2%+4.3%+12.4%
Piotroski ScoreFundamental quality 0–965545
Debt / EquityFinancial leverage0.07x1.35x0.23x
Net DebtTotal debt minus cash-$7M-$5M-$134M$3.4B-$282M
Cash & Equiv.Liquid assets$27M$5M$134M$532M$551M
Total DebtShort + long-term debt$19M$305,000$0$4.0B$269M
Interest CoverageEBIT ÷ Interest expense-1.57x46.08x-7.20x63.45x
HALO leads this category, winning 4 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

Evenly matched — HALO and INVA each lead in 3 of 6 comparable metrics.

A $10,000 investment in INVA five years ago would be worth $19,448 today (with dividends reinvested), compared to $82 for SNOA. Over the past 12 months, INVA leads with a +23.2% total return vs SNOA's -62.6%. The 3-year compound annual growth rate (CAGR) favors HALO at 28.4% vs SNOA's -60.7% — a key indicator of consistent wealth creation.

MetricFENC logoFENCFennec Pharmaceut…SNOA logoSNOASonoma Pharmaceut…HALO logoHALOHalozyme Therapeu…PRGO logoPRGOPerrigo Company p…INVA logoINVAInnoviva, Inc.
YTD ReturnYear-to-date-9.8%-67.0%-8.8%-13.6%+15.2%
1-Year ReturnPast 12 months+11.6%-62.6%-5.3%-52.0%+23.2%
3-Year ReturnCumulative with dividends-12.8%-94.0%+111.8%-58.1%+96.0%
5-Year ReturnCumulative with dividends+15.9%-99.2%+39.1%-60.3%+94.5%
10-Year ReturnCumulative with dividends-42.3%-99.9%+559.7%-77.7%+95.6%
CAGR (3Y)Annualised 3-year return-4.5%-60.7%+28.4%-25.2%+25.1%
Evenly matched — HALO and INVA each lead in 3 of 6 comparable metrics.

Risk & Volatility

INVA leads this category, winning 2 of 2 comparable metrics.

INVA is the less volatile stock with a 0.11 beta — it tends to amplify market swings less than FENC's 1.78 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. INVA currently trades 91.0% from its 52-week high vs SNOA's 17.3% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricFENC logoFENCFennec Pharmaceut…SNOA logoSNOASonoma Pharmaceut…HALO logoHALOHalozyme Therapeu…PRGO logoPRGOPerrigo Company p…INVA logoINVAInnoviva, Inc.
Beta (5Y)Sensitivity to S&P 5001.78x0.84x0.51x1.21x0.11x
52-Week HighHighest price in past year$9.92$6.92$82.22$28.44$25.15
52-Week LowLowest price in past year$5.65$0.85$47.50$9.23$16.52
% of 52W HighCurrent price vs 52-week peak+69.9%+17.3%+78.0%+41.2%+91.0%
RSI (14)Momentum oscillator 0–10053.431.347.753.144.7
Avg Volume (50D)Average daily shares traded177K189K1.4M3.3M604K
INVA leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

PRGO leads this category, winning 1 of 1 comparable metric.

Analyst consensus: FENC as "Buy", HALO as "Buy", PRGO as "Hold", INVA as "Buy". Consensus price targets imply 209.1% upside for PRGO (target: $36) vs 17.9% for HALO (target: $76). PRGO is the only dividend payer here at 9.82% yield — a key consideration for income-focused portfolios.

MetricFENC logoFENCFennec Pharmaceut…SNOA logoSNOASonoma Pharmaceut…HALO logoHALOHalozyme Therapeu…PRGO logoPRGOPerrigo Company p…INVA logoINVAInnoviva, Inc.
Analyst RatingConsensus buy/hold/sellBuyBuyHoldBuy
Price TargetConsensus 12-month target$18.00$75.60$36.20$40.00
# AnalystsCovering analysts7273610
Dividend YieldAnnual dividend ÷ price+9.8%
Dividend StreakConsecutive years of raises100
Dividend / ShareAnnual DPS$1.15
Buyback YieldShare repurchases ÷ mkt cap+0.1%+0.0%+4.5%0.0%+0.3%
PRGO leads this category, winning 1 of 1 comparable metric.
Key Takeaway

HALO leads in 1 of 6 categories (Profitability & Efficiency). INVA leads in 1 (Risk & Volatility). 3 tied.

Best OverallHalozyme Therapeutics, Inc. (HALO)Leads 1 of 6 categories
Loading custom metrics...

FENC vs SNOA vs HALO vs PRGO vs INVA: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is FENC or SNOA or HALO or PRGO or INVA a better buy right now?

For growth investors, Fennec Pharmaceuticals Inc.

(FENC) is the stronger pick with 123. 7% revenue growth year-over-year, versus -2. 8% for Perrigo Company plc (PRGO). Innoviva, Inc. (INVA) offers the better valuation at 6. 9x trailing P/E (7. 3x forward), making it the more compelling value choice. Analysts rate Fennec Pharmaceuticals Inc. (FENC) a "Buy" — based on 7 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — FENC or SNOA or HALO or PRGO or INVA?

On trailing P/E, Innoviva, Inc.

(INVA) is the cheapest at 6. 9x versus Halozyme Therapeutics, Inc. at 25. 0x. On forward P/E, Perrigo Company plc is actually cheaper at 5. 5x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Halozyme Therapeutics, Inc. wins at 0. 35x versus Innoviva, Inc. 's 0. 71x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.

03

Which is the better long-term investment — FENC or SNOA or HALO or PRGO or INVA?

Over the past 5 years, Innoviva, Inc.

(INVA) delivered a total return of +94. 5%, compared to -99. 2% for Sonoma Pharmaceuticals, Inc. (SNOA). Over 10 years, the gap is even starker: HALO returned +559. 7% versus SNOA's -99. 9%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — FENC or SNOA or HALO or PRGO or INVA?

By beta (market sensitivity over 5 years), Innoviva, Inc.

(INVA) is the lower-risk stock at 0. 11β versus Fennec Pharmaceuticals Inc. 's 1. 78β — meaning FENC is approximately 1462% more volatile than INVA relative to the S&P 500. On balance sheet safety, Sonoma Pharmaceuticals, Inc. (SNOA) carries a lower debt/equity ratio of 7% versus 135% for Perrigo Company plc — giving it more financial flexibility in a downturn.

05

Which is growing faster — FENC or SNOA or HALO or PRGO or INVA?

By revenue growth (latest reported year), Fennec Pharmaceuticals Inc.

(FENC) is pulling ahead at 123. 7% versus -2. 8% for Perrigo Company plc (PRGO). On earnings-per-share growth, the picture is similar: Innoviva, Inc. grew EPS 816. 7% year-over-year, compared to -723. 2% for Perrigo Company plc. Over a 3-year CAGR, HALO leads at 28. 4% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — FENC or SNOA or HALO or PRGO or INVA?

Innoviva, Inc.

(INVA) is the more profitable company, earning 63. 8% net margin versus -33. 5% for Perrigo Company plc — meaning it keeps 63. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: HALO leads at 58. 4% versus -26. 0% for SNOA. At the gross margin level — before operating expenses — FENC leads at 93. 3%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is FENC or SNOA or HALO or PRGO or INVA more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, Halozyme Therapeutics, Inc. (HALO) is the more undervalued stock at a PEG of 0. 35x versus Innoviva, Inc. 's 0. 71x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Perrigo Company plc (PRGO) trades at 5. 5x forward P/E versus 54. 3x for Fennec Pharmaceuticals Inc. — 48. 7x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for PRGO: 209. 1% to $36. 20.

08

Which pays a better dividend — FENC or SNOA or HALO or PRGO or INVA?

In this comparison, PRGO (9.

8% yield) pays a dividend. FENC, SNOA, HALO, INVA do not pay a meaningful dividend and should not be held primarily for income.

09

Is FENC or SNOA or HALO or PRGO or INVA better for a retirement portfolio?

For long-horizon retirement investors, Innoviva, Inc.

(INVA) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 11)). Fennec Pharmaceuticals Inc. (FENC) carries a higher beta of 1. 78 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (INVA: +95. 6%, FENC: -42. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between FENC and SNOA and HALO and PRGO and INVA?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: FENC is a small-cap high-growth stock; SNOA is a small-cap quality compounder stock; HALO is a small-cap high-growth stock; PRGO is a small-cap income-oriented stock; INVA is a small-cap high-growth stock. PRGO pays a dividend while FENC, SNOA, HALO, INVA do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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Revenue Growth>
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(FENC: 78.7% · SNOA: 22.0%)

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