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GOVX vs IOVA vs IMVT vs NKTR vs RCUS

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
GOVX
GeoVax Labs, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$2M
5Y Perf.-96.3%
IOVA
Iovance Biotherapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.27B
5Y Perf.-89.2%
IMVT
Immunovant, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$5.53B
5Y Perf.-22.6%
NKTR
Nektar Therapeutics

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.69B
5Y Perf.-66.5%
RCUS
Arcus Biosciences, Inc.

Biotechnology

HealthcareNYSE • US
Market Cap$2.50B
5Y Perf.+44.7%

GOVX vs IOVA vs IMVT vs NKTR vs RCUS — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
GOVX logoGOVX
IOVA logoIOVA
IMVT logoIMVT
NKTR logoNKTR
RCUS logoRCUS
IndustryBiotechnologyBiotechnologyBiotechnologyBiotechnologyBiotechnology
Market Cap$2M$1.27B$5.53B$1.69B$2.50B
Revenue (TTM)$2M$286M$0.00$55M$236M
Net Income (TTM)$-21M$-354M$-464M$-164M$-369M
Gross Margin100.0%114.5%99.6%90.7%
Operating Margin-8.7%-127.2%-237.9%-168.6%
Total Debt$843.17B$48M$98K$149M$99M
Cash & Equiv.$6M$163M$714M$15M$222M

GOVX vs IOVA vs IMVT vs NKTR vs RCUSLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

GOVX
IOVA
IMVT
NKTR
RCUS
StockSep 20May 26Return
GeoVax Labs, Inc. (GOVX)1003.7-96.3%
Iovance Biotherapeu… (IOVA)10010.8-89.2%
Immunovant, Inc. (IMVT)10077.4-22.6%
Nektar Therapeutics (NKTR)10033.5-66.5%
Arcus Biosciences, … (RCUS)100144.7+44.7%

Price return only. Dividends and distributions are not included.

Quick Verdict: GOVX vs IOVA vs IMVT vs NKTR vs RCUS

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: IMVT leads in 2 of 6 categories (5-stock set), making it the strongest pick for profitability and margin quality and capital preservation and lower volatility. GeoVax Labs, Inc. is the stronger pick specifically for operational efficiency and capital deployment. IOVA and NKTR also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
GOVX
GeoVax Labs, Inc.
The Growth Play

GOVX is the #2 pick in this set and the best alternative if growth exposure is your priority.

  • Rev growth -37.1%, EPS growth 81.4%, 3Y rev CAGR 212.5%
  • -0.0% ROA vs NKTR's -62.8%, ROIC -0.0% vs -57.2%
Best for: growth exposure
IOVA
Iovance Biotherapeutics, Inc.
The Growth Leader

IOVA ranks third and is worth considering specifically for growth.

  • 60.6% revenue growth vs NKTR's -43.9%
Best for: growth
IMVT
Immunovant, Inc.
The Income Pick

IMVT carries the broadest edge in this set and is the clearest fit for income & stability and long-term compounding.

  • beta 1.37
  • 173.6% 10Y total return vs RCUS's 45.9%
  • Lower volatility, beta 1.37, Low D/E 0.0%, current ratio 11.16x
  • Beta 1.37, current ratio 11.16x
Best for: income & stability and long-term compounding
NKTR
Nektar Therapeutics
The Momentum Pick

NKTR is the clearest fit if your priority is momentum.

  • +8.2% vs IOVA's +13.4%
Best for: momentum
RCUS
Arcus Biosciences, Inc.
The Healthcare Pick

Among these 5 stocks, RCUS doesn't own a clear edge in any measured category.

Best for: healthcare exposure
See the full category breakdown
CategoryWinnerWhy
GrowthIOVA logoIOVA60.6% revenue growth vs NKTR's -43.9%
Quality / MarginsIMVT logoIMVT3.2% margin vs GOVX's -8.6%
Stability / SafetyIMVT logoIMVTBeta 1.37 vs GOVX's 2.23, lower leverage
DividendsTieNone of these 5 stocks pay a meaningful dividend
Momentum (1Y)NKTR logoNKTR+8.2% vs IOVA's +13.4%
Efficiency (ROA)GOVX logoGOVX-0.0% ROA vs NKTR's -62.8%, ROIC -0.0% vs -57.2%

GOVX vs IOVA vs IMVT vs NKTR vs RCUS — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

GOVXGeoVax Labs, Inc.
FY 2022
NIH Grants
100.0%$81,526
IOVAIovance Biotherapeutics, Inc.

Segment breakdown not available.

IMVTImmunovant, Inc.

Segment breakdown not available.

NKTRNektar Therapeutics
FY 2025
Non Cash Royalty Revenue Related To Sale Of Future Royalties
99.5%$55M
License Collaboration And Other Revenue
0.5%$300,000
RCUSArcus Biosciences, Inc.
FY 2025
License And Development Services
87.4%$221M
Development Services
6.7%$17M
R&D Services
3.2%$8M
License
2.8%$7M

GOVX vs IOVA vs IMVT vs NKTR vs RCUS — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLGOVXLAGGINGRCUS

Income & Cash Flow (Last 12 Months)

IOVA leads this category, winning 5 of 6 comparable metrics.

IOVA and IMVT operate at a comparable scale, with $286M and $0 in trailing revenue. Profitability is closely matched — net margins range from -123.9% (IOVA) to -8.6% (GOVX). On growth, IOVA holds the edge at +44.8% YoY revenue growth, suggesting stronger near-term business momentum.

MetricGOVX logoGOVXGeoVax Labs, Inc.IOVA logoIOVAIovance Biotherap…IMVT logoIMVTImmunovant, Inc.NKTR logoNKTRNektar Therapeuti…RCUS logoRCUSArcus Biosciences…
RevenueTrailing 12 months$2M$286M$0$55M$236M
EBITDAEarnings before interest/tax-$22M-$330M-$487M-$130M-$391M
Net IncomeAfter-tax profit-$21M-$354M-$464M-$164M-$369M
Free Cash FlowCash after capex-$21M-$305M-$423M-$209M-$489M
Gross MarginGross profit ÷ Revenue+100.0%+114.5%+99.6%+90.7%
Operating MarginEBIT ÷ Revenue-8.7%-127.2%-2.4%-168.6%
Net MarginNet income ÷ Revenue-8.6%-123.9%-3.0%-156.4%
FCF MarginFCF ÷ Revenue-8.6%-106.8%-3.8%-2.1%
Rev. Growth (YoY)Latest quarter vs prior year-100.0%+44.8%-25.3%-39.3%
EPS Growth (YoY)Latest quarter vs prior year+86.9%+47.2%+19.7%-4.5%+10.5%
IOVA leads this category, winning 5 of 6 comparable metrics.

Valuation Metrics

GOVX leads this category, winning 2 of 3 comparable metrics.
MetricGOVX logoGOVXGeoVax Labs, Inc.IOVA logoIOVAIovance Biotherap…IMVT logoIMVTImmunovant, Inc.NKTR logoNKTRNektar Therapeuti…RCUS logoRCUSArcus Biosciences…
Market CapShares × price$2M$1.3B$5.5B$1.7B$2.5B
Enterprise ValueMkt cap + debt − cash$843.2B$1.2B$4.8B$1.8B$2.4B
Trailing P/EPrice ÷ TTM EPS-0.08x-3.26x-9.97x-8.57x-7.54x
Forward P/EPrice ÷ next-FY EPS est.
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple
Price / SalesMarket cap ÷ Revenue0.68x4.82x30.64x10.11x
Price / BookPrice ÷ Book value/share0.00x1.82x5.83x15.66x4.22x
Price / FCFMarket cap ÷ FCF
GOVX leads this category, winning 2 of 3 comparable metrics.

Profitability & Efficiency

GOVX leads this category, winning 4 of 9 comparable metrics.

GOVX delivers a -0.0% return on equity — every $100 of shareholder capital generates $-0 in annual profit, vs $-4 for NKTR. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to NKTR's 1.66x. On the Piotroski fundamental quality scale (0–9), IOVA scores 5/9 vs RCUS's 0/9, reflecting solid financial health.

MetricGOVX logoGOVXGeoVax Labs, Inc.IOVA logoIOVAIovance Biotherap…IMVT logoIMVTImmunovant, Inc.NKTR logoNKTRNektar Therapeuti…RCUS logoRCUSArcus Biosciences…
ROE (TTM)Return on equity-0.0%-50.2%-47.1%-4.0%-69.0%
ROA (TTM)Return on assets-0.0%-38.8%-44.1%-62.8%-35.3%
ROICReturn on invested capital-0.0%-48.9%-57.2%-64.1%
ROCEReturn on capital employed-0.0%-51.6%-66.1%-55.7%-42.1%
Piotroski ScoreFundamental quality 0–945220
Debt / EquityFinancial leverage0.22x0.07x0.00x1.66x0.16x
Net DebtTotal debt minus cash$843.2B-$115M-$714M$134M-$123M
Cash & Equiv.Liquid assets$6M$163M$714M$15M$222M
Total DebtShort + long-term debt$843.2B$48M$98,000$149M$99M
Interest CoverageEBIT ÷ Interest expense-4.74x-13.38x
GOVX leads this category, winning 4 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

NKTR leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in IMVT five years ago would be worth $16,241 today (with dividends reinvested), compared to $197 for GOVX. Over the past 12 months, NKTR leads with a +818.2% total return vs IOVA's +13.4%. The 3-year compound annual growth rate (CAGR) favors NKTR at 93.3% vs GOVX's -43.9% — a key indicator of consistent wealth creation.

MetricGOVX logoGOVXGeoVax Labs, Inc.IOVA logoIOVAIovance Biotherap…IMVT logoIMVTImmunovant, Inc.NKTR logoNKTRNektar Therapeuti…RCUS logoRCUSArcus Biosciences…
YTD ReturnYear-to-date+750.2%+40.9%+5.1%+92.0%+6.5%
1-Year ReturnPast 12 months+89.4%+13.4%+96.1%+818.2%+209.6%
3-Year ReturnCumulative with dividends-82.4%-49.9%+40.9%+621.8%+24.9%
5-Year ReturnCumulative with dividends-98.0%-87.6%+62.4%-72.3%-18.6%
10-Year ReturnCumulative with dividends-96.0%-34.3%+173.6%-59.1%+45.9%
CAGR (3Y)Annualised 3-year return-43.9%-20.6%+12.1%+93.3%+7.7%
NKTR leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

IMVT leads this category, winning 2 of 2 comparable metrics.

IMVT is the less volatile stock with a 1.37 beta — it tends to amplify market swings less than GOVX's 2.23 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMVT currently trades 90.5% from its 52-week high vs GOVX's 40.0% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricGOVX logoGOVXGeoVax Labs, Inc.IOVA logoIOVAIovance Biotherap…IMVT logoIMVTImmunovant, Inc.NKTR logoNKTRNektar Therapeuti…RCUS logoRCUSArcus Biosciences…
Beta (5Y)Sensitivity to S&P 5002.23x2.01x1.37x1.85x1.95x
52-Week HighHighest price in past year$4.40$5.63$30.09$109.00$28.72
52-Week LowLowest price in past year$0.12$1.64$13.36$7.99$7.06
% of 52W HighCurrent price vs 52-week peak+40.0%+63.1%+90.5%+76.5%+86.3%
RSI (14)Momentum oscillator 0–10067.863.160.253.460.5
Avg Volume (50D)Average daily shares traded217K16.2M1.4M991K1.2M
IMVT leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: IOVA as "Buy", IMVT as "Buy", NKTR as "Buy", RCUS as "Buy". Consensus price targets imply 67.2% upside for IMVT (target: $46) vs -43.7% for IOVA (target: $2).

MetricGOVX logoGOVXGeoVax Labs, Inc.IOVA logoIOVAIovance Biotherap…IMVT logoIMVTImmunovant, Inc.NKTR logoNKTRNektar Therapeuti…RCUS logoRCUSArcus Biosciences…
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuy
Price TargetConsensus 12-month target$2.00$45.50$132.83$30.00
# AnalystsCovering analysts20233318
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises1
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

GOVX leads in 2 of 6 categories (Valuation Metrics, Profitability & Efficiency). IOVA leads in 1 (Income & Cash Flow).

Best OverallGeoVax Labs, Inc. (GOVX)Leads 2 of 6 categories
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GOVX vs IOVA vs IMVT vs NKTR vs RCUS: Key Questions Answered

8 questions · data-driven answers · updated daily

01

Is GOVX or IOVA or IMVT or NKTR or RCUS a better buy right now?

For growth investors, Iovance Biotherapeutics, Inc.

(IOVA) is the stronger pick with 60. 6% revenue growth year-over-year, versus -43. 9% for Nektar Therapeutics (NKTR). Analysts rate Iovance Biotherapeutics, Inc. (IOVA) a "Buy" — based on 20 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — GOVX or IOVA or IMVT or NKTR or RCUS?

Over the past 5 years, Immunovant, Inc.

(IMVT) delivered a total return of +62. 4%, compared to -98. 0% for GeoVax Labs, Inc. (GOVX). Over 10 years, the gap is even starker: IMVT returned +173. 6% versus GOVX's -96. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — GOVX or IOVA or IMVT or NKTR or RCUS?

By beta (market sensitivity over 5 years), Immunovant, Inc.

(IMVT) is the lower-risk stock at 1. 37β versus GeoVax Labs, Inc. 's 2. 23β — meaning GOVX is approximately 62% more volatile than IMVT relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 166% for Nektar Therapeutics — giving it more financial flexibility in a downturn.

04

Which is growing faster — GOVX or IOVA or IMVT or NKTR or RCUS?

By revenue growth (latest reported year), Iovance Biotherapeutics, Inc.

(IOVA) is pulling ahead at 60. 6% versus -43. 9% for Nektar Therapeutics (NKTR). On earnings-per-share growth, the picture is similar: GeoVax Labs, Inc. grew EPS 81. 4% year-over-year, compared to -45. 2% for Immunovant, Inc.. Over a 3-year CAGR, GOVX leads at 212. 5% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — GOVX or IOVA or IMVT or NKTR or RCUS?

Immunovant, Inc.

(IMVT) is the more profitable company, earning 0. 0% net margin versus -862. 3% for GeoVax Labs, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: IMVT leads at 0. 0% versus -869. 3% for GOVX. At the gross margin level — before operating expenses — GOVX leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Which pays a better dividend — GOVX or IOVA or IMVT or NKTR or RCUS?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

07

Is GOVX or IOVA or IMVT or NKTR or RCUS better for a retirement portfolio?

For long-horizon retirement investors, Immunovant, Inc.

(IMVT) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (+173. 6% 10Y return). GeoVax Labs, Inc. (GOVX) carries a higher beta of 2. 23 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (IMVT: +173. 6%, GOVX: -96. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

08

What are the main differences between GOVX and IOVA and IMVT and NKTR and RCUS?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: GOVX is a small-cap quality compounder stock; IOVA is a small-cap high-growth stock; IMVT is a small-cap quality compounder stock; NKTR is a small-cap quality compounder stock; RCUS is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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  • Market Cap > $100B
  • Gross Margin > 60%
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High-Growth Disruptor

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 22%
  • Gross Margin > 68%
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IMVT

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NKTR

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  • Market Cap > $100B
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RCUS

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  • Market Cap > $100B
  • Gross Margin > 54%
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(GOVX: -100.0% · IOVA: 44.8%)

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