Biotechnology
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5 / 10Stock Comparison
HRMY vs DBVT vs PRGO vs IQV vs MCK
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Drug Manufacturers - Specialty & Generic
Medical - Diagnostics & Research
Medical - Distribution
HRMY vs DBVT vs PRGO vs IQV vs MCK — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Drug Manufacturers - Specialty & Generic | Medical - Diagnostics & Research | Medical - Distribution |
| Market Cap | $1.82B | $1712.35T | $1.61B | $30.32B | $92.15B |
| Revenue (TTM) | $899M | $0.00 | $4.18B | $16.63B | $403.43B |
| Net Income (TTM) | $146M | $-168M | $-1.82B | $1.39B | $4.76B |
| Gross Margin | 76.5% | — | 34.2% | 26.1% | 3.6% |
| Operating Margin | 21.1% | — | -4.1% | 13.9% | 1.5% |
| Forward P/E | 9.0x | — | 5.6x | 14.1x | 19.3x |
| Total Debt | $240M | $22M | $3.97B | $16.17B | $7.39B |
| Cash & Equiv. | $753M | $194M | $532M | $1.98B | $5.69B |
HRMY vs DBVT vs PRGO vs IQV vs MCK — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Aug 20 | May 26 | Return |
|---|---|---|---|
| Harmony Biosciences… (HRMY) | 100 | 88.7 | -11.3% |
| DBV Technologies S.… (DBVT) | 100 | 92.5 | -7.5% |
| Perrigo Company plc (PRGO) | 100 | 22.4 | -77.6% |
| IQVIA Holdings Inc. (IQV) | 100 | 109.1 | +9.1% |
| McKesson Corporation (MCK) | 100 | 490.3 | +390.3% |
Price return only. Dividends and distributions are not included.
Quick Verdict: HRMY vs DBVT vs PRGO vs IQV vs MCK
Each card shows where this stock fits in a portfolio — not just who wins on paper.
HRMY carries the broadest edge in this set and is the clearest fit for growth exposure and sleep-well-at-night.
- Rev growth 21.5%, EPS growth 8.0%, 3Y rev CAGR 25.6%
- Lower volatility, beta 0.79, Low D/E 27.5%, current ratio 3.60x
- 21.5% revenue growth vs DBVT's -100.0%
- 16.2% margin vs PRGO's -43.5%
DBVT ranks third and is worth considering specifically for momentum.
- +110.4% vs PRGO's -51.2%
PRGO is the #2 pick in this set and the best alternative if income & stability and defensive is your priority.
- Dividend streak 10 yrs, beta 1.18, yield 9.8%
- Beta 1.18, yield 9.8%, current ratio 2.76x
- Lower P/E (5.6x vs 19.3x)
- 9.8% yield, 10-year raise streak, vs MCK's 0.4%, (3 stocks pay no dividend)
IQV is the clearest fit if your priority is valuation efficiency.
- PEG 0.35 vs MCK's 0.49
MCK is the clearest fit if your priority is long-term compounding.
- 348.1% 10Y total return vs IQV's 166.5%
- Beta 0.04 vs IQV's 1.33
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 21.5% revenue growth vs DBVT's -100.0% | |
| Value | Lower P/E (5.6x vs 19.3x) | |
| Quality / Margins | 16.2% margin vs PRGO's -43.5% | |
| Stability / Safety | Beta 0.04 vs IQV's 1.33 | |
| Dividends | 9.8% yield, 10-year raise streak, vs MCK's 0.4%, (3 stocks pay no dividend) | |
| Momentum (1Y) | +110.4% vs PRGO's -51.2% | |
| Efficiency (ROA) | 12.0% ROA vs DBVT's -89.0% |
HRMY vs DBVT vs PRGO vs IQV vs MCK — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
HRMY vs DBVT vs PRGO vs IQV vs MCK — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
MCK leads in 2 of 6 categories
HRMY leads 1 • PRGO leads 1 • DBVT leads 0 • IQV leads 0 • 2 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
HRMY leads this category, winning 5 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
MCK and DBVT operate at a comparable scale, with $403.4B and $0 in trailing revenue. HRMY is the more profitable business, keeping 16.2% of every revenue dollar as net income compared to PRGO's -43.5%. On growth, HRMY holds the edge at +16.6% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $899M | $0 | $4.2B | $16.6B | $403.4B |
| EBITDAEarnings before interest/tax | $209M | -$112M | $58M | $3.5B | $6.8B |
| Net IncomeAfter-tax profit | $146M | -$168M | -$1.8B | $1.4B | $4.8B |
| Free Cash FlowCash after capex | $342M | -$151M | $108M | $2.7B | $6.0B |
| Gross MarginGross profit ÷ Revenue | +76.5% | — | +34.2% | +26.1% | +3.6% |
| Operating MarginEBIT ÷ Revenue | +21.1% | — | -4.1% | +13.9% | +1.5% |
| Net MarginNet income ÷ Revenue | +16.2% | — | -43.5% | +8.3% | +1.2% |
| FCF MarginFCF ÷ Revenue | +38.0% | — | +2.6% | +16.1% | +1.5% |
| Rev. Growth (YoY)Latest quarter vs prior year | +16.6% | — | -7.2% | +8.4% | +6.0% |
| EPS Growth (YoY)Latest quarter vs prior year | -29.5% | +91.5% | -56.4% | +15.0% | +37.0% |
Valuation Metrics
PRGO leads this category, winning 3 of 7 comparable metrics.
Valuation Metrics
At 11.6x trailing earnings, HRMY trades at a 60% valuation discount to MCK's 29.2x P/E. Adjusting for growth (PEG ratio), IQV offers better value at 0.56x vs MCK's 0.75x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $1.8B | $1712.35T | $1.6B | $30.3B | $92.1B |
| Enterprise ValueMkt cap + debt − cash | $1.3B | $1712.35T | $5.1B | $44.5B | $93.8B |
| Trailing P/EPrice ÷ TTM EPS | 11.59x | -0.76x | -1.14x | 22.79x | 29.25x |
| Forward P/EPrice ÷ next-FY EPS est. | 8.95x | — | 5.56x | 14.06x | 19.28x |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | 0.56x | 0.75x |
| EV / EBITDAEnterprise value multiple | 5.58x | — | 7.42x | 12.97x | 18.74x |
| Price / SalesMarket cap ÷ Revenue | 2.09x | — | 0.38x | 1.86x | 0.26x |
| Price / BookPrice ÷ Book value/share | 2.11x | 0.66x | 0.55x | 4.67x | — |
| Price / FCFMarket cap ÷ FCF | 5.23x | — | 11.12x | 14.78x | 17.63x |
Profitability & Efficiency
MCK leads this category, winning 5 of 9 comparable metrics.
Profitability & Efficiency
MCK delivers a 3.0% return on equity — every $100 of shareholder capital generates $3 in annual profit, vs $-130 for DBVT. DBVT carries lower financial leverage with a 0.13x debt-to-equity ratio, signaling a more conservative balance sheet compared to IQV's 2.44x. On the Piotroski fundamental quality scale (0–9), MCK scores 6/9 vs IQV's 4/9, reflecting solid financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | +17.2% | -130.2% | -50.7% | +22.1% | +3.0% |
| ROA (TTM)Return on assets | +12.0% | -89.0% | -19.8% | +4.7% | +5.7% |
| ROICReturn on invested capital | +42.0% | — | +3.7% | +8.7% | +5.4% |
| ROCEReturn on capital employed | +22.6% | -145.7% | +4.3% | +11.0% | +30.5% |
| Piotroski ScoreFundamental quality 0–9 | 4 | 4 | 4 | 4 | 6 |
| Debt / EquityFinancial leverage | 0.28x | 0.13x | 1.35x | 2.44x | — |
| Net DebtTotal debt minus cash | -$513M | -$172M | $3.4B | $14.2B | $1.7B |
| Cash & Equiv.Liquid assets | $753M | $194M | $532M | $2.0B | $5.7B |
| Total DebtShort + long-term debt | $240M | $22M | $4.0B | $16.2B | $7.4B |
| Interest CoverageEBIT ÷ Interest expense | 21.78x | -189.82x | -7.20x | 3.10x | 33.79x |
Total Returns (Dividends Reinvested)
MCK leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in MCK five years ago would be worth $38,689 today (with dividends reinvested), compared to $3,090 for DBVT. Over the past 12 months, DBVT leads with a +110.4% total return vs PRGO's -51.2%. The 3-year compound annual growth rate (CAGR) favors MCK at 27.3% vs PRGO's -25.2% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -15.9% | +4.9% | -13.5% | -20.7% | -8.5% |
| 1-Year ReturnPast 12 months | -6.0% | +110.4% | -51.2% | +16.5% | +4.6% |
| 3-Year ReturnCumulative with dividends | -12.8% | +19.7% | -58.1% | -5.9% | +106.4% |
| 5-Year ReturnCumulative with dividends | +13.3% | -69.1% | -60.1% | -23.8% | +286.9% |
| 10-Year ReturnCumulative with dividends | -15.1% | -87.0% | -77.7% | +166.5% | +348.1% |
| CAGR (3Y)Annualised 3-year return | -4.5% | +6.2% | -25.2% | -2.0% | +27.3% |
Risk & Volatility
Evenly matched — HRMY and MCK each lead in 1 of 2 comparable metrics.
Risk & Volatility
MCK is the less volatile stock with a 0.04 beta — it tends to amplify market swings less than IQV's 1.33 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. HRMY currently trades 76.9% from its 52-week high vs PRGO's 41.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.79x | 1.26x | 1.18x | 1.33x | 0.04x |
| 52-Week HighHighest price in past year | $40.87 | $26.18 | $28.44 | $247.05 | $999.00 |
| 52-Week LowLowest price in past year | $25.52 | $7.53 | $9.23 | $134.65 | $637.00 |
| % of 52W HighCurrent price vs 52-week peak | +76.9% | +76.3% | +41.2% | +72.3% | +75.3% |
| RSI (14)Momentum oscillator 0–100 | 67.6 | 48.1 | 60.9 | 58.5 | 16.2 |
| Avg Volume (50D)Average daily shares traded | 791K | 252K | 3.4M | 1.6M | 757K |
Analyst Outlook
Evenly matched — PRGO and MCK each lead in 1 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: HRMY as "Buy", DBVT as "Buy", PRGO as "Hold", IQV as "Buy", MCK as "Buy". Consensus price targets imply 131.8% upside for DBVT (target: $46) vs 26.3% for IQV (target: $226). For income investors, PRGO offers the higher dividend yield at 9.81% vs MCK's 0.36%.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Hold | Buy | Buy |
| Price TargetConsensus 12-month target | $46.80 | $46.33 | $20.00 | $225.63 | $1006.50 |
| # AnalystsCovering analysts | 13 | 15 | 36 | 44 | 31 |
| Dividend YieldAnnual dividend ÷ price | — | — | +9.8% | — | +0.4% |
| Dividend StreakConsecutive years of raises | — | 0 | 10 | 2 | 17 |
| Dividend / ShareAnnual DPS | — | — | $1.15 | — | $2.69 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | +4.1% | +3.4% |
MCK leads in 2 of 6 categories (Profitability & Efficiency, Total Returns). HRMY leads in 1 (Income & Cash Flow). 2 tied.
HRMY vs DBVT vs PRGO vs IQV vs MCK: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is HRMY or DBVT or PRGO or IQV or MCK a better buy right now?
For growth investors, Harmony Biosciences Holdings, Inc.
(HRMY) is the stronger pick with 21. 5% revenue growth year-over-year, versus -2. 8% for Perrigo Company plc (PRGO). Harmony Biosciences Holdings, Inc. (HRMY) offers the better valuation at 11. 6x trailing P/E (9. 0x forward), making it the more compelling value choice. Analysts rate Harmony Biosciences Holdings, Inc. (HRMY) a "Buy" — based on 13 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — HRMY or DBVT or PRGO or IQV or MCK?
On trailing P/E, Harmony Biosciences Holdings, Inc.
(HRMY) is the cheapest at 11. 6x versus McKesson Corporation at 29. 2x. On forward P/E, Perrigo Company plc is actually cheaper at 5. 6x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: IQVIA Holdings Inc. wins at 0. 35x versus McKesson Corporation's 0. 49x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.
03Which is the better long-term investment — HRMY or DBVT or PRGO or IQV or MCK?
Over the past 5 years, McKesson Corporation (MCK) delivered a total return of +286.
9%, compared to -69. 1% for DBV Technologies S. A. (DBVT). Over 10 years, the gap is even starker: MCK returned +348. 1% versus DBVT's -87. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — HRMY or DBVT or PRGO or IQV or MCK?
By beta (market sensitivity over 5 years), McKesson Corporation (MCK) is the lower-risk stock at 0.
04β versus IQVIA Holdings Inc. 's 1. 33β — meaning IQV is approximately 2991% more volatile than MCK relative to the S&P 500. On balance sheet safety, DBV Technologies S. A. (DBVT) carries a lower debt/equity ratio of 13% versus 2% for IQVIA Holdings Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — HRMY or DBVT or PRGO or IQV or MCK?
By revenue growth (latest reported year), Harmony Biosciences Holdings, Inc.
(HRMY) is pulling ahead at 21. 5% versus -2. 8% for Perrigo Company plc (PRGO). On earnings-per-share growth, the picture is similar: McKesson Corporation grew EPS 14. 9% year-over-year, compared to -723. 2% for Perrigo Company plc. Over a 3-year CAGR, HRMY leads at 25. 6% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — HRMY or DBVT or PRGO or IQV or MCK?
Harmony Biosciences Holdings, Inc.
(HRMY) is the more profitable company, earning 18. 3% net margin versus -33. 5% for Perrigo Company plc — meaning it keeps 18. 3% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: HRMY leads at 24. 0% versus 0. 0% for DBVT. At the gross margin level — before operating expenses — HRMY leads at 77. 2%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is HRMY or DBVT or PRGO or IQV or MCK more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, IQVIA Holdings Inc. (IQV) is the more undervalued stock at a PEG of 0. 35x versus McKesson Corporation's 0. 49x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Perrigo Company plc (PRGO) trades at 5. 6x forward P/E versus 19. 3x for McKesson Corporation — 13. 7x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for DBVT: 131. 8% to $46. 33.
08Which pays a better dividend — HRMY or DBVT or PRGO or IQV or MCK?
In this comparison, PRGO (9.
8% yield), MCK (0. 4% yield) pay a dividend. HRMY, DBVT, IQV do not pay a meaningful dividend and should not be held primarily for income.
09Is HRMY or DBVT or PRGO or IQV or MCK better for a retirement portfolio?
For long-horizon retirement investors, McKesson Corporation (MCK) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.
04), +348. 1% 10Y return). Both have compounded well over 10 years (MCK: +348. 1%, DBVT: -87. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between HRMY and DBVT and PRGO and IQV and MCK?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: HRMY is a small-cap high-growth stock; DBVT is a mega-cap quality compounder stock; PRGO is a small-cap income-oriented stock; IQV is a mid-cap quality compounder stock; MCK is a mid-cap high-growth stock. PRGO pays a dividend while HRMY, DBVT, IQV, MCK do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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