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Stock Comparison

HROW vs NUVL vs IMVT vs RXRX vs INVA

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
HROW
Harrow Health, Inc.

Drug Manufacturers - Specialty & Generic

HealthcareNASDAQ • US
Market Cap$1.45B
5Y Perf.+337.8%
NUVL
Nuvalent, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$7.53B
5Y Perf.+461.1%
IMVT
Immunovant, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$5.53B
5Y Perf.+160.2%
RXRX
Recursion Pharmaceuticals, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.46B
5Y Perf.-89.2%
INVA
Innoviva, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.93B
5Y Perf.+60.8%

HROW vs NUVL vs IMVT vs RXRX vs INVA — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
HROW logoHROW
NUVL logoNUVL
IMVT logoIMVT
RXRX logoRXRX
INVA logoINVA
IndustryDrug Manufacturers - Specialty & GenericBiotechnologyBiotechnologyBiotechnologyBiotechnology
Market Cap$1.45B$7.53B$5.53B$1.46B$1.93B
Revenue (TTM)$272M$0.00$0.00$66M$424M
Net Income (TTM)$-5M$-450M$-464M$-560M$504M
Gross Margin75.1%-34.4%76.2%
Operating Margin11.2%-8.8%14.8%
Forward P/E82.9x11.9x
Total Debt$252M$0.00$98K$78M$269M
Cash & Equiv.$73M$262M$714M$743M$551M

HROW vs NUVL vs IMVT vs RXRX vs INVALong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

HROW
NUVL
IMVT
RXRX
INVA
StockJul 21May 26Return
Harrow Health, Inc. (HROW)100437.8+337.8%
Nuvalent, Inc. (NUVL)100561.1+461.1%
Immunovant, Inc. (IMVT)100260.2+160.2%
Recursion Pharmaceu… (RXRX)10010.8-89.2%
Innoviva, Inc. (INVA)100160.8+60.8%

Price return only. Dividends and distributions are not included.

Quick Verdict: HROW vs NUVL vs IMVT vs RXRX vs INVA

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: INVA leads in 4 of 7 categories (5-stock set), making it the strongest pick for valuation and capital efficiency and profitability and margin quality. Harrow Health, Inc. is the stronger pick specifically for growth and revenue expansion. IMVT also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
HROW
Harrow Health, Inc.
The Growth Play

HROW is the #2 pick in this set and the best alternative if growth exposure and long-term compounding is your priority.

  • Rev growth 36.4%, EPS growth 71.4%, 3Y rev CAGR 45.4%
  • 9.1% 10Y total return vs NUVL's 446.1%
  • 36.4% revenue growth vs IMVT's -21.3%
Best for: growth exposure and long-term compounding
NUVL
Nuvalent, Inc.
The Healthcare Pick

NUVL lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
IMVT
Immunovant, Inc.
The Momentum Pick

IMVT ranks third and is worth considering specifically for momentum.

  • +96.1% vs RXRX's -22.0%
Best for: momentum
RXRX
Recursion Pharmaceuticals, Inc.
The Growth Angle

Among these 5 stocks, RXRX doesn't own a clear edge in any measured category.

Best for: healthcare exposure
INVA
Innoviva, Inc.
The Income Pick

INVA carries the broadest edge in this set and is the clearest fit for income & stability and sleep-well-at-night.

  • Dividend streak 0 yrs, beta 0.13
  • Lower volatility, beta 0.13, Low D/E 22.9%, current ratio 14.64x
  • Beta 0.13, current ratio 14.64x
  • Better valuation composite
Best for: income & stability and sleep-well-at-night
See the full category breakdown
CategoryWinnerWhy
GrowthHROW logoHROW36.4% revenue growth vs IMVT's -21.3%
ValueINVA logoINVABetter valuation composite
Quality / MarginsINVA logoINVA118.9% margin vs RXRX's -8.4%
Stability / SafetyINVA logoINVABeta 0.13 vs RXRX's 3.18
DividendsTieNone of these 5 stocks pay a meaningful dividend
Momentum (1Y)IMVT logoIMVT+96.1% vs RXRX's -22.0%
Efficiency (ROA)INVA logoINVA32.4% ROA vs IMVT's -44.1%

HROW vs NUVL vs IMVT vs RXRX vs INVA — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

HROWHarrow Health, Inc.
FY 2025
Product Sales Net
99.9%$272M
Other Revenues
0.1%$394,000
NUVLNuvalent, Inc.

Segment breakdown not available.

IMVTImmunovant, Inc.

Segment breakdown not available.

RXRXRecursion Pharmaceuticals, Inc.
FY 2025
License and Service
99.4%$74M
Grant
0.6%$425,000
INVAInnoviva, Inc.
FY 2025
Royalty
57.5%$236M
Product
41.8%$172M
License And Other Revenue
0.7%$3M

HROW vs NUVL vs IMVT vs RXRX vs INVA — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLINVALAGGINGRXRX

Income & Cash Flow (Last 12 Months)

INVA leads this category, winning 5 of 6 comparable metrics.

INVA and IMVT operate at a comparable scale, with $424M and $0 in trailing revenue. INVA is the more profitable business, keeping 118.9% of every revenue dollar as net income compared to RXRX's -8.4%. On growth, HROW holds the edge at +33.3% YoY revenue growth, suggesting stronger near-term business momentum.

MetricHROW logoHROWHarrow Health, In…NUVL logoNUVLNuvalent, Inc.IMVT logoIMVTImmunovant, Inc.RXRX logoRXRXRecursion Pharmac…INVA logoINVAInnoviva, Inc.
RevenueTrailing 12 months$272M$0$0$66M$424M
EBITDAEarnings before interest/tax$59M-$346M-$487M-$521M$86M
Net IncomeAfter-tax profit-$5M-$450M-$464M-$560M$504M
Free Cash FlowCash after capex$73M-$313M-$423M-$326M$181M
Gross MarginGross profit ÷ Revenue+75.1%-34.4%+76.2%
Operating MarginEBIT ÷ Revenue+11.2%-8.8%+14.8%
Net MarginNet income ÷ Revenue-1.9%-8.4%+118.9%
FCF MarginFCF ÷ Revenue+26.8%-4.9%+42.8%
Rev. Growth (YoY)Latest quarter vs prior year+33.3%-56.1%+10.6%
EPS Growth (YoY)Latest quarter vs prior year-5.3%-17.8%+19.7%+56.0%+4.0%
INVA leads this category, winning 5 of 6 comparable metrics.

Valuation Metrics

INVA leads this category, winning 2 of 4 comparable metrics.
MetricHROW logoHROWHarrow Health, In…NUVL logoNUVLNuvalent, Inc.IMVT logoIMVTImmunovant, Inc.RXRX logoRXRXRecursion Pharmac…INVA logoINVAInnoviva, Inc.
Market CapShares × price$1.5B$7.5B$5.5B$1.5B$1.9B
Enterprise ValueMkt cap + debt − cash$1.6B$7.3B$4.8B$797M$1.7B
Trailing P/EPrice ÷ TTM EPS-278.93x-17.50x-9.97x-2.27x6.91x
Forward P/EPrice ÷ next-FY EPS est.82.86x11.91x
PEG RatioP/E ÷ EPS growth rate0.67x
EV / EBITDAEnterprise value multiple8.10x
Price / SalesMarket cap ÷ Revenue5.34x19.58x4.55x
Price / BookPrice ÷ Book value/share27.56x5.96x5.83x1.29x1.65x
Price / FCFMarket cap ÷ FCF9.88x
INVA leads this category, winning 2 of 4 comparable metrics.

Profitability & Efficiency

INVA leads this category, winning 6 of 9 comparable metrics.

INVA delivers a 46.5% return on equity — every $100 of shareholder capital generates $46 in annual profit, vs $-54 for RXRX. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to HROW's 4.84x. On the Piotroski fundamental quality scale (0–9), INVA scores 5/9 vs NUVL's 1/9, reflecting solid financial health.

MetricHROW logoHROWHarrow Health, In…NUVL logoNUVLNuvalent, Inc.IMVT logoIMVTImmunovant, Inc.RXRX logoRXRXRecursion Pharmac…INVA logoINVAInnoviva, Inc.
ROE (TTM)Return on equity-10.1%-42.8%-47.1%-54.3%+46.5%
ROA (TTM)Return on assets-1.4%-37.8%-44.1%-40.6%+32.4%
ROICReturn on invested capital+9.5%-32.5%-95.8%+14.2%
ROCEReturn on capital employed+10.2%-34.4%-66.1%-50.1%+12.4%
Piotroski ScoreFundamental quality 0–941245
Debt / EquityFinancial leverage4.84x0.00x0.07x0.23x
Net DebtTotal debt minus cash$179M-$262M-$714M-$665M-$282M
Cash & Equiv.Liquid assets$73M$262M$714M$743M$551M
Total DebtShort + long-term debt$252M$0$98,000$78M$269M
Interest CoverageEBIT ÷ Interest expense0.53x-26.85x-336.46x63.45x
INVA leads this category, winning 6 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

NUVL leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in NUVL five years ago would be worth $54,613 today (with dividends reinvested), compared to $1,179 for RXRX. Over the past 12 months, IMVT leads with a +96.1% total return vs RXRX's -22.0%. The 3-year compound annual growth rate (CAGR) favors NUVL at 39.5% vs RXRX's -16.4% — a key indicator of consistent wealth creation.

MetricHROW logoHROWHarrow Health, In…NUVL logoNUVLNuvalent, Inc.IMVT logoIMVTImmunovant, Inc.RXRX logoRXRXRecursion Pharmac…INVA logoINVAInnoviva, Inc.
YTD ReturnYear-to-date-21.8%+1.5%+5.1%-22.1%+14.7%
1-Year ReturnPast 12 months+58.8%+53.5%+96.1%-22.0%+21.7%
3-Year ReturnCumulative with dividends+43.0%+171.2%+40.9%-41.6%+95.2%
5-Year ReturnCumulative with dividends+378.0%+446.1%+62.4%-88.2%+94.4%
10-Year ReturnCumulative with dividends+914.3%+446.1%+173.6%-81.8%+94.9%
CAGR (3Y)Annualised 3-year return+12.7%+39.5%+12.1%-16.4%+25.0%
NUVL leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

INVA leads this category, winning 2 of 2 comparable metrics.

INVA is the less volatile stock with a 0.13 beta — it tends to amplify market swings less than RXRX's 3.18 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. INVA currently trades 90.7% from its 52-week high vs RXRX's 45.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricHROW logoHROWHarrow Health, In…NUVL logoNUVLNuvalent, Inc.IMVT logoIMVTImmunovant, Inc.RXRX logoRXRXRecursion Pharmac…INVA logoINVAInnoviva, Inc.
Beta (5Y)Sensitivity to S&P 5002.13x1.09x1.37x3.18x0.13x
52-Week HighHighest price in past year$54.85$113.02$30.09$7.18$25.15
52-Week LowLowest price in past year$21.12$63.56$13.36$2.80$16.52
% of 52W HighCurrent price vs 52-week peak+71.2%+90.6%+90.5%+45.5%+90.7%
RSI (14)Momentum oscillator 0–10054.652.960.249.539.9
Avg Volume (50D)Average daily shares traded733K544K1.4M12.5M621K
INVA leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: HROW as "Buy", NUVL as "Buy", IMVT as "Buy", RXRX as "Hold", INVA as "Buy". Consensus price targets imply 236.4% upside for RXRX (target: $11) vs 41.0% for NUVL (target: $144).

MetricHROW logoHROWHarrow Health, In…NUVL logoNUVLNuvalent, Inc.IMVT logoIMVTImmunovant, Inc.RXRX logoRXRXRecursion Pharmac…INVA logoINVAInnoviva, Inc.
Analyst RatingConsensus buy/hold/sellBuyBuyBuyHoldBuy
Price TargetConsensus 12-month target$75.67$144.40$45.50$11.00$37.67
# AnalystsCovering analysts1014231010
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises00
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%0.0%+0.2%
Insufficient data to determine a leader in this category.
Key Takeaway

INVA leads in 4 of 6 categories (Income & Cash Flow, Valuation Metrics). NUVL leads in 1 (Total Returns).

Best OverallInnoviva, Inc. (INVA)Leads 4 of 6 categories
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HROW vs NUVL vs IMVT vs RXRX vs INVA: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is HROW or NUVL or IMVT or RXRX or INVA a better buy right now?

For growth investors, Harrow Health, Inc.

(HROW) is the stronger pick with 36. 4% revenue growth year-over-year, versus 18. 5% for Innoviva, Inc. (INVA). Innoviva, Inc. (INVA) offers the better valuation at 6. 9x trailing P/E (11. 9x forward), making it the more compelling value choice. Analysts rate Harrow Health, Inc. (HROW) a "Buy" — based on 10 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — HROW or NUVL or IMVT or RXRX or INVA?

On forward P/E, Innoviva, Inc.

is actually cheaper at 11. 9x.

03

Which is the better long-term investment — HROW or NUVL or IMVT or RXRX or INVA?

Over the past 5 years, Nuvalent, Inc.

(NUVL) delivered a total return of +446. 1%, compared to -88. 2% for Recursion Pharmaceuticals, Inc. (RXRX). Over 10 years, the gap is even starker: HROW returned +914. 3% versus RXRX's -81. 8%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — HROW or NUVL or IMVT or RXRX or INVA?

By beta (market sensitivity over 5 years), Innoviva, Inc.

(INVA) is the lower-risk stock at 0. 13β versus Recursion Pharmaceuticals, Inc. 's 3. 18β — meaning RXRX is approximately 2419% more volatile than INVA relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 5% for Harrow Health, Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — HROW or NUVL or IMVT or RXRX or INVA?

By revenue growth (latest reported year), Harrow Health, Inc.

(HROW) is pulling ahead at 36. 4% versus 18. 5% for Innoviva, Inc. (INVA). On earnings-per-share growth, the picture is similar: Innoviva, Inc. grew EPS 816. 7% year-over-year, compared to -48. 9% for Nuvalent, Inc.. Over a 3-year CAGR, HROW leads at 45. 4% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — HROW or NUVL or IMVT or RXRX or INVA?

Innoviva, Inc.

(INVA) is the more profitable company, earning 63. 8% net margin versus -863. 4% for Recursion Pharmaceuticals, Inc. — meaning it keeps 63. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: INVA leads at 38. 5% versus -867. 9% for RXRX. At the gross margin level — before operating expenses — HROW leads at 75. 1%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is HROW or NUVL or IMVT or RXRX or INVA more undervalued right now?

On forward earnings alone, Innoviva, Inc.

(INVA) trades at 11. 9x forward P/E versus 82. 9x for Harrow Health, Inc. — 70. 9x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for RXRX: 236. 4% to $11. 00.

08

Which pays a better dividend — HROW or NUVL or IMVT or RXRX or INVA?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

09

Is HROW or NUVL or IMVT or RXRX or INVA better for a retirement portfolio?

For long-horizon retirement investors, Innoviva, Inc.

(INVA) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 13)). Recursion Pharmaceuticals, Inc. (RXRX) carries a higher beta of 3. 18 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (INVA: +94. 9%, RXRX: -81. 8%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between HROW and NUVL and IMVT and RXRX and INVA?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: HROW is a small-cap high-growth stock; NUVL is a small-cap quality compounder stock; IMVT is a small-cap quality compounder stock; RXRX is a small-cap high-growth stock; INVA is a small-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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